Photo by Bill Dillard

Find hotels in Southeast Missouri, MO from ¥7,945
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Southeast Missouri
Cabin
Pet friendly
Check prices for these dates
Our top choices for Southeast Missouri hotels

Motel 6 Bonne Terre, MO
Motel 6 Bonne Terre, MOBonne Terre
6.8 out of 10, (30 reviews)
The price is ¥8,652
¥9,462 total
includes taxes & fees
Feb 22 - Feb 23

Super 8 by Wyndham Bonne Terre
Super 8 by Wyndham Bonne TerreBonne Terre
7.0 out of 10, Good, (547 reviews)
cleanliness Scenic Super 8 motel near outdoor adventures and historic mine tours in Bonne Terre.
The price is ¥8,229
¥8,998 total
includes taxes & fees
Feb 22 - Feb 23

Econo Lodge Kennett
Econo Lodge KennettKennett
5.6 out of 10, (179 reviews)
cleanliness Experience a relaxing golf retreat with convenient on-site pool access in Kennett.
The price is ¥7,933
¥9,056 total
includes taxes & fees
Mar 12 - Mar 13

Echo Bluff State Park
Echo Bluff State ParkEminence
9.4 out of 10, Exceptional, (221 reviews)
cleanliness Beautiful riverside escape with scenic trails and modern comforts in Eminence.
The price is ¥22,554
¥23,846 total
includes taxes & fees
Mar 5 - Mar 6

Rockwood Inn
Rockwood InnCape Girardeau
10.0 out of 10, Exceptional, (19 reviews)
cleanliness Stay close to Show Me Center in this charming Cape Girardeau retreat.
The price is ¥23,499
¥26,510 total
includes taxes & fees
Feb 18 - Feb 19

OYO Malden Airport Inn
OYO Malden Airport InnMalden
7.0 out of 10, Good, (68 reviews)
cleanliness Located close to Morris State Park, this convenient hotel offers free parking and WiFi.
The price is ¥9,641
¥11,355 total
includes taxes & fees
Feb 17 - Feb 18

Econo Lodge Dexter
Econo Lodge DexterDexter
6.8 out of 10, (254 reviews)
cleanliness Unwind in this welcoming Dexter motel with free breakfast and parking options.
The price is ¥9,192
¥10,321 total
includes taxes & fees
Mar 12 - Mar 13

Town House Inn Cape Giradreau
Town House Inn Cape GiradreauCape Girardeau
6.2 out of 10, (210 reviews)
cleanliness Affordable roadside comfort with 24-hour service and nearby attractions.
The price is ¥9,271
¥10,832 total
includes taxes & fees
Mar 8 - Mar 9

Travelodge by Wyndham Dexter
Travelodge by Wyndham DexterDexter
7.6 out of 10, Good, (394 reviews)
cleanliness Convenient hotel near Dexter's Heritage House with Penny's Diner on-site.
The price is ¥12,297
¥13,808 total
includes taxes & fees
Feb 18 - Feb 19

Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (581 reviews)
cleanliness Experience scenic golf views with an indoor pool and hot tub on site.
The price is ¥9,641
¥10,976 total
includes taxes & fees
Mar 5 - Mar 6

Quality Inn Farmington
Quality Inn FarmingtonFarmington
7.6 out of 10, Good, (870 reviews)
cleanliness Experience outdoor adventures near Wilson Rozier Park from this friendly hotel.
The price is ¥8,359
¥9,957 total
includes taxes & fees
Mar 1 - Mar 2

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,006 reviews)
cleanliness Enjoy a quiet retreat with indoor pool and hot tub near shopping in Cape Girardeau.
The price is ¥13,904
¥15,686 total
includes taxes & fees
Feb 16 - Feb 17

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (109 reviews)
cleanliness Experience comfort at this riverside hotel with indoor pool and free breakfast.
The price is ¥13,810
¥15,718 total
includes taxes & fees
Feb 25 - Feb 26

Hampton Inn By Hilton Dexter
Hampton Inn By Hilton DexterDexter
10.0 out of 10, Exceptional, (11 reviews)
The price is ¥16,344
¥18,353 total
includes taxes & fees
Feb 28 - Mar 1

Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
8.2 out of 10, Very Good, (894 reviews)
The price is ¥12,361
¥14,795 total
includes taxes & fees
Feb 22 - Feb 23

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (791 reviews)
cleanliness Cozy riverside retreat with indoor pool and free breakfast for Cape travelers.
The price is ¥16,344
¥18,438 total
includes taxes & fees
Mar 8 - Mar 9

Arcadia Academy
Arcadia AcademyArcadia
9.8 out of 10, Exceptional, (11 reviews)
cleanliness Charming Arcadia B&B offers valley views with free breakfast and garden terrace.
The price is ¥21,040
¥22,824 total
includes taxes & fees
Feb 18 - Feb 19

Dexter Inn
Dexter InnDexter
7.0 out of 10, Good, (335 reviews)
cleanliness Contemporary hotel in Dexter with complimentary WiFi and parking for travelers.
The price is ¥10,985
¥12,335 total
includes taxes & fees
Mar 8 - Mar 9

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (157 reviews)
cleanliness Relax at this contemporary hotel with an indoor pool in Cape Girardeau.
The price is ¥14,369
¥16,211 total
includes taxes & fees
Feb 26 - Feb 27

Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
8.0 out of 10, Very Good, (1,000 reviews)
cleanliness Comfy lodging with convenient dining access and peaceful surroundings.
The price is ¥8,120
¥9,245 total
includes taxes & fees
Feb 22 - Feb 23
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Southeast Missouri
Cabin

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (49 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Central United States attractions
Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Clearwater Lake.

Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Cape Girardeau
10/10 Excellent
More cheap stays in Southeast Missouri

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
The price is ¥7,532 per night from Feb 24 to Feb 25
¥7,532
¥7,945 total
Feb 24 - Feb 25
includes taxes & fees
7.8/10 Good! (1,001 reviews)
Hotels in Southeast Missouri with star-rating

4 Star Hotels
2 properties
Explore a world of travel with Expedia
- Cape Girardeau Hotels
- Guest Houses in Sikeston
- Pet-Friendly Hotels in Farmington
- Rv Parks in Southeast Missouri
- Aparthotels in Ellington
- Luxury Hotels in Belgrade
- Poplar Bluff Hotels
- Motels in Black
- Luxury Hotels in Sikeston
- Bunker Hotels
- Black Hotels
- Luxury Hotels in Bloomfield
- Rv Parks in Black
- B&B in Ste Genevieve
- Hotels near Washington State Park
- Motels in Jackson
- Ski Hotels in Farmington
- Apartments in Cape Girardeau County
- B&B in Annapolis
- Dexter Hotels
- Doniphan Hotels
- Rv Parks in Jackson












































































































