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Find hotels in Southeast Missouri, MO from ￥9,542

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Our top choices for Southeast Missouri hotels

Desk, laptop workspace, free WiFi, bed sheets
Motel 6 Bonne Terre, MO

Motel 6 Bonne Terre, MO

Motel 6 Bonne Terre, MO
2.0 star property
Bonne Terre
7.0 out of 10, Good, (27)
"Clean, was perfect for my one night stay in the area"
United States
Dave
The price is ￥10,207
￥11,161 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Motel 6 Bonne Terre, MO
Lobby
Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre
2.0 star property
Bonne Terre
7.0 out of 10, Good, (540)
"The room was spacious and very clean. The parking was free and close to the entrance, excellent water pressure for the shower, and the staff was friendly and professional."
United States
Raymond
The price is ￥7,842
￥8,575 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Super 8 by Wyndham Bonne Terre
Front of property
Echo Bluff State Park

Echo Bluff State Park

Echo Bluff State Park
2.5 star property
Eminence
9.6 out of 10, Exceptional, (217)
"The cabin was beautiful, comfy, & private! The park was FANTASTIC for hiking & scenery! We hope to return and maybe bring family or friends. The staff were all friendly too! :)"
United States
Joanne
The price is ￥24,301
￥25,692 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Echo Bluff State Park
Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi
Rockwood Inn

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (19)
"My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! "
United States
Kim
The price is ￥23,722
￥26,762 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Rockwood Inn
Reception
OYO Malden Airport Inn

OYO Malden Airport Inn

OYO Malden Airport Inn
2.5 star property
Malden
7.0 out of 10, Good, (68)
"Clean room, quiet. "
United States
Jennifer
The price is ￥7,624
￥9,185 total
includes taxes & fees
Jan 5 - Jan 6, 2026
OYO Malden Airport Inn
Lobby
Econo Lodge Kennett

Econo Lodge Kennett

Econo Lodge Kennett
2.0 star property
Kennett
5.4 out of 10, (170)
"Yes. It Was All Good "
United States
Stephanie
The price is ￥8,107
￥9,254 total
includes taxes & fees
Jan 31 - Feb 1, 2026
Econo Lodge Kennett
Desk, free WiFi
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.0 out of 10, (206)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is ￥8,578
￥10,021 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Town House Inn Cape Giradreau
Desk, iron/ironing board, free WiFi, bed sheets
Econo Lodge Dexter

Econo Lodge Dexter

Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (253)
"The stay was very nice. Animal friendly, staff is super nice and house keeping is very respectful. I appreciate everyone. "
United States
Michelle
The price is ￥9,303
￥10,447 total
includes taxes & fees
Jan 29 - Jan 30, 2026
Econo Lodge Dexter
Breakfast, lunch, dinner served; American cuisine
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (390)
"Clean room, friendly staff and quiet stay."
United States
Margo
The price is ￥12,049
￥13,530 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Travelodge by Wyndham Dexter
Lobby
Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
9.0 out of 10, Wonderful, (577)
"Clean, friendly staff enjoyed the stay"
United States
John
The price is ￥20,120
￥22,909 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Crown Pointe Lodge, BW Signature Collection
Room, 2 Queen Beds
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (104)
"It was a nice stay"
United States
Douglas
The price is ￥13,941
￥15,867 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Tru By Hilton Cape Girardeau
Business center
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1003)
"Awesome stay!"
United States
Breckin
The price is ￥14,036
￥15,833 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Drury Inn & Suites Cape Girardeau
Premium bedding, desk, iron/ironing board, free cribs/infant beds
Quality Inn Farmington

Quality Inn Farmington

Quality Inn Farmington
2.5 star property
Farmington
7.6 out of 10, Good, (863)
"The staff was friendly. We had a few issues with our stay but overall was good. Love there breakfast variety "
United States
edith
The price is ￥8,049
￥9,609 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Quality Inn Farmington
Studio, 1 King Bed
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
10.0 out of 10, Exceptional, (5)
"Great stay "
United States
Ashley
The price is ￥16,499
￥18,527 total
includes taxes & fees
Jan 30 - Jan 31, 2026
Hampton Inn By Hilton Dexter
Exterior
OYO Hickory House Inn

OYO Hickory House Inn

OYO Hickory House Inn
2.5 star property
Dexter
5.6 out of 10, (134)
"We enjoyed every moment of our stay. Wonderful service—everyone was friendly and helpful."
United States
Albert
The price is ￥6,978
￥8,774 total
includes taxes & fees
Jan 29 - Jan 30, 2026
OYO Hickory House Inn
Exterior
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (886)
"Room was clean and spacious."
United States
George
The price is ￥10,947
￥13,209 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Candlewood Suites Cape Girardeau by IHG
Courtyard
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (785)
"Excellent stay"
United States
Christina
The price is ￥16,499
￥18,613 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hampton Inn Cape Girardeau I 55 East
Business center
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very Good, (1001)
"The staff were welcoming everything was clean and updated"
United States
Danielle
The price is ￥8,382
￥9,542 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Baymont Inn and Suites by Wyndham Farmington, MO
Seasonal outdoor pool, open 10:00 AM to 9:00 PM, pool umbrellas
Dexter Inn

Dexter Inn

Dexter Inn
2.5 star property
Dexter
7.0 out of 10, Good, (333)
"Room was nice and spacious."
United States
Rebecca
The price is ￥10,165
￥11,414 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Dexter Inn
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (145)
"Lovely staff clean hotel comfortable beds "
United States
Kastriot
The price is ￥13,725
￥15,483 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Fairfield Inn & Suites by Marriott Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:Jan 9 - Jan 11

Image gallery for Johnson's Shut-ins State Park

Full-size fridge, microwave, oven, stovetop

Johnson's Shut-ins State Park

3.0 star property
Middle Brook
10/10Exceptional (1 review)
Member Price available
Price is ￥41,597
￥87,958 total
includes taxes & fees
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Johnson's Shut-ins State Park
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Stay near popular Central United States attractions

Panorama of Academic Hall, Southeast Missouri State University

Southeast Missouri State University

4.4/5 (137 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
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A huge granite boulder located in Elephant Rocks State Park
Photo by Pat Long
Open Photo by Pat Long

Elephant Rocks State Park

4.8/5 (52 reviews)
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
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Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri
Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg: Moark Regional Railroad Museum HOURS: Saturdays 1 p.m. - 4 p.m. It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history. This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! #MTTS2014 #minitakesthestates #go11 #train
Photo by Bill Dillard
Open Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"This Drury is our preferred place to stay when visiting family in Cape Girardeau. The hotel Staff is always warm and small town friendly! The hotel is nice and the breakfast buffet is outstanding!! "
Michael 2-night trip
Posted 2 days ago
Drury Plaza Hotel Cape Girardeau Conference Center

More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St Farmington MO
The price is ￥8,382 per night from Jan 9 to Jan 10
￥8,382
￥9,542 total
Jan 9 - Jan 10, 2026
includes taxes & fees
7.8/10 Good! (1,002 reviews)

Hotels in Southeast Missouri with star-rating