Find hotels in Southeast Missouri, MO from ¥9,007
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Compare 606 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.
Our top choices for Southeast Missouri hotels

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1018)
The price is ¥13,283
¥14,983 total
includes taxes & fees
Oct 12 - Oct 13

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
9.6 out of 10, Exceptional, (1016)
The price is ¥13,283
¥14,043 total
includes taxes & fees
Sep 28 - Sep 29

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
9.4 out of 10, Exceptional, (1000)
The price is ¥13,283
¥14,983 total
includes taxes & fees
Oct 19 - Oct 20

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
9.4 out of 10, Exceptional, (1011)
The price is ¥13,283
¥15,271 total
includes taxes & fees
Oct 19 - Oct 20

EC Reed's Mercantile and Hotel
EC Reed's Mercantile and Hotel
9.6 out of 10, Exceptional, (78)

Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Hayti Caruthersville
9.4 out of 10, Exceptional, (1006)
The price is ¥13,874
¥15,812 total
includes taxes & fees
Sep 28 - Sep 29
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Southeast Missouri, MO
Showing deals for:Oct 3 - Oct 5
Image gallery for Tiny Houses of French Village

Tiny Houses of French Village
French Village
10/10Exceptional (3 reviews)
10% off
Price is ¥35,870
¥84,146 total
includes taxes & fees
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Stay near popular Southeast Missouri attractions
K Bridge Recreation Area
K Bridge Recreation Area
5/5(1 review)
Explore the great outdoors at K Bridge Recreation Area, a lovely green space in Annapolis. While you're in the area, stroll along the riverfront.
Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Sam A. Baker State Park to K Bridge Recreation Area.

Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Sikeston, MO
10/10 Excellent
More cheap stays in Southeast Missouri
More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St, Farmington, MO
The price is ¥7,912 per night from Oct 19 to Oct 20
¥7,912
¥9,007 total
Oct 19 - Oct 20
includes taxes & fees
8/10 Very Good! (1,012 reviews)
Hotels in Southeast Missouri with star-rating
Hotels in Southeast Missouri with star-rating

4 Star Hotels
1 properties
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Hotels in Southeast Missouri Neighborhoods
Stay near popular Southeast Missouri attractions
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Southeast Missouri Hotels by Brand
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