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Our top choices for Southeast Missouri hotels

The Farmstead Hotel

The Farmstead Hotel
2.5 star property
Caruthersville
8.8 out of 10, Excellent, (480 reviews)
  • cleanliness
    Experience a quiet escape at this casino hotel with free parking and WiFi.
"Clean room, very nice staff"
United States
Mack
The price is ¥11,763
¥13,378 total
includes taxes & fees
Feb 3 - Feb 4
The Farmstead Hotel

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very Good, (1,003 reviews)
  • cleanliness
    Affordable roadside comfort with 24-hour front desk and clean accommodations.
"Very clean and staff was very friendly!"
United States
Sherry
The price is ¥8,654
¥9,129 total
includes taxes & fees
Feb 15 - Feb 16
Motel 6 Poplar Bluff, MO

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,003 reviews)
  • cleanliness
    Comfortable stay near Central Park with convenient amenities and friendly staff.
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is ¥12,364
¥14,093 total
includes taxes & fees
Feb 15 - Feb 16
Best Western Plus Sikeston I-55

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very Good, (45 reviews)
  • cleanliness
    Stay at a comfortable hotel in Marston with free full breakfast each morning.
"Great hotel, great staff"
United States
Dmitry
The price is ¥10,030
¥11,456 total
includes taxes & fees
Feb 3 - Feb 4
Super 8 By Wyndham Marston

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (337 reviews)
  • cleanliness
    Discover a cozy retreat in Mountain View with access to hiking trails and fitness.
"Staff was very friendly."
United States
Joyce
The price is ¥14,380
¥15,590 total
includes taxes & fees
Feb 15 - Feb 16
Honeysuckle Inn - Mountain View

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very Good, (737 reviews)
  • cleanliness
    Comfy motel in Portageville with helpful staff and free perks for travelers.
"Parking was good, staff was great "
United States
Corey
New Orleans Inn Portageville

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,004 reviews)
  • cleanliness
    Explore Cape Girardeau with a central hotel and indoor pool for year-round swims.
"Breakfast was very good and staff was extremely friendly and rooms were very clean "
United States
Rex
The price is ¥14,704
¥16,588 total
includes taxes & fees
Feb 8 - Feb 9
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,005 reviews)
  • cleanliness
    Experience peaceful comfort and attentive service at this Jackson escape point.
"Suited our purpose for overnight on a road trip "
United States
Angela
The price is ¥12,381
¥13,089 total
includes taxes & fees
Feb 8 - Feb 9
Drury Inn & Suites Jackson MO

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (733 reviews)
  • cleanliness
    Peaceful oasis in Sikeston offering complimentary breakfast and hassle-free parking.
"Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ."
United States
Becky
The price is ¥8,818
¥10,050 total
includes taxes & fees
Feb 15 - Feb 16
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi
2.0 star property
Potosi
7.0 out of 10, Good, (383 reviews)
  • cleanliness
    Enjoy free breakfast and comfy rooms in this welcoming Potosi hotel.
" Our stay was good. Employees were nice, room was clean, "
United States
Kenneth
The price is ¥8,552
¥9,343 total
includes taxes & fees
Feb 3 - Feb 4
Super 8 by Wyndham Potosi

The Riverstone Hotel

The Riverstone Hotel
2.5 star property
Charleston
6.8 out of 10, (408 reviews)
  • cleanliness
    Stay in a peaceful atmosphere close to Cape Girardeau with daily breakfast.
"The staff was very friendly and accommodating "
United States
Arturo
The price is ¥10,586
¥11,748 total
includes taxes & fees
Feb 15 - Feb 16
The Riverstone Hotel

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
Sikeston
9.2 out of 10, Wonderful, (54 reviews)
  • cleanliness
    Enjoy comfort and convenience near Central Park at this modern Sikeston hotel.
"Clean rooms great staff"
United States
IRA
The price is ¥16,972
¥19,216 total
includes taxes & fees
Feb 8 - Feb 9
Fairfield Inn & Suites by Marriott Sikeston

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (108 reviews)
  • cleanliness
    Experience comfort at this riverside hotel with indoor pool and free breakfast.
"Very nice room!"
United States
Niki
The price is ¥13,834
¥15,746 total
includes taxes & fees
Feb 11 - Feb 12
Tru By Hilton Cape Girardeau

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (473 reviews)
  • cleanliness
    Explore Sikeston with comfort and convenience at this friendly, well-equipped hotel.
"Great place for an overnight stay. I will be back!"
United States
Jenny
The price is ¥14,602
¥16,533 total
includes taxes & fees
Feb 8 - Feb 9
Hampton Inn Sikeston

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (698 reviews)
"Conveniently located, clean, friendly staff."
United States
Philip
The price is ¥13,025
¥14,097 total
includes taxes & fees
Feb 8 - Feb 9
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (496 reviews)
  • cleanliness
    Experience the thrilling casino action at this riverside Cape Girardeau spot.
"The room was clean and I was able to check in a bit early."
United States
Sara
The price is ¥14,459
¥16,313 total
includes taxes & fees
Feb 16 - Feb 17
The Riverview

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (447 reviews)
  • cleanliness
    Stay productive in Sikeston with a modern hotel offering free amenities and fitness.
"Stay was excellent "
United States
Kourtney
The price is ¥14,395
¥16,299 total
includes taxes & fees
Feb 8 - Feb 9
Holiday Inn Express & Suites Sikeston Southwest by IHG

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Experience quiet comfort near restaurants with free breakfast and indoor pool.
"As always it was a perfect visit"
United States
John
The price is ¥13,567
¥15,598 total
includes taxes & fees
Feb 15 - Feb 16
Drury Inn & Suites Sikeston, MO

Quality Inn Farmington

Quality Inn Farmington
2.5 star property
Farmington
7.6 out of 10, Good, (867 reviews)
  • cleanliness
    Experience outdoor adventures near Wilson Rozier Park from this friendly hotel.
"The staff was friendly. We had a few issues with our stay but overall was good. Love there breakfast variety "
United States
edith
The price is ¥7,953
¥9,495 total
includes taxes & fees
Feb 15 - Feb 16
Quality Inn Farmington

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (622 reviews)
  • cleanliness
    Rest near Charleston with convenient amenities, free breakfast, and parking.
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is ¥9,612
¥10,666 total
includes taxes & fees
Feb 3 - Feb 4
Super 8 by Wyndham Charleston/Sikeston East MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Central United States attractions

Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg:

Moark Regional Railroad Museum
HOURS: Saturdays 1 p.m. - 4 p.m.

It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history.

This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! 

#MTTS2014 #minitakesthestates #go11
#train
Photo by Bill Dillard
Open Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Hotels in Southeast Missouri with star-rating