Photo by Bill Dillard

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Our top choices for Southeast Missouri hotels

The Farmstead Hotel
The Farmstead HotelCaruthersville
8.8 out of 10, Excellent, (480 reviews)
cleanliness Experience a quiet escape at this casino hotel with free parking and WiFi.
The price is ¥11,763
¥13,378 total
includes taxes & fees
Feb 3 - Feb 4

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MOPoplar Bluff
8.0 out of 10, Very Good, (1,003 reviews)
cleanliness Affordable roadside comfort with 24-hour front desk and clean accommodations.
The price is ¥8,654
¥9,129 total
includes taxes & fees
Feb 15 - Feb 16

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very Good, (1,003 reviews)
cleanliness Comfortable stay near Central Park with convenient amenities and friendly staff.
The price is ¥12,364
¥14,093 total
includes taxes & fees
Feb 15 - Feb 16

Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.0 out of 10, Very Good, (45 reviews)
cleanliness Stay at a comfortable hotel in Marston with free full breakfast each morning.
The price is ¥10,030
¥11,456 total
includes taxes & fees
Feb 3 - Feb 4

Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (337 reviews)
cleanliness Discover a cozy retreat in Mountain View with access to hiking trails and fitness.
The price is ¥14,380
¥15,590 total
includes taxes & fees
Feb 15 - Feb 16

New Orleans Inn Portageville
New Orleans Inn PortagevillePortageville
8.0 out of 10, Very Good, (737 reviews)
cleanliness Comfy motel in Portageville with helpful staff and free perks for travelers.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,004 reviews)
cleanliness Explore Cape Girardeau with a central hotel and indoor pool for year-round swims.
The price is ¥14,704
¥16,588 total
includes taxes & fees
Feb 8 - Feb 9

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,005 reviews)
cleanliness Experience peaceful comfort and attentive service at this Jackson escape point.
The price is ¥12,381
¥13,089 total
includes taxes & fees
Feb 8 - Feb 9

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very Good, (733 reviews)
cleanliness Peaceful oasis in Sikeston offering complimentary breakfast and hassle-free parking.
The price is ¥8,818
¥10,050 total
includes taxes & fees
Feb 15 - Feb 16

Super 8 by Wyndham Potosi
Super 8 by Wyndham PotosiPotosi
7.0 out of 10, Good, (383 reviews)
cleanliness Enjoy free breakfast and comfy rooms in this welcoming Potosi hotel.
The price is ¥8,552
¥9,343 total
includes taxes & fees
Feb 3 - Feb 4

The Riverstone Hotel
The Riverstone HotelCharleston
6.8 out of 10, (408 reviews)
cleanliness Stay in a peaceful atmosphere close to Cape Girardeau with daily breakfast.
The price is ¥10,586
¥11,748 total
includes taxes & fees
Feb 15 - Feb 16

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (54 reviews)
cleanliness Enjoy comfort and convenience near Central Park at this modern Sikeston hotel.
The price is ¥16,972
¥19,216 total
includes taxes & fees
Feb 8 - Feb 9

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (108 reviews)
cleanliness Experience comfort at this riverside hotel with indoor pool and free breakfast.
The price is ¥13,834
¥15,746 total
includes taxes & fees
Feb 11 - Feb 12

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (473 reviews)
cleanliness Explore Sikeston with comfort and convenience at this friendly, well-equipped hotel.
The price is ¥14,602
¥16,533 total
includes taxes & fees
Feb 8 - Feb 9

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (698 reviews)
The price is ¥13,025
¥14,097 total
includes taxes & fees
Feb 8 - Feb 9

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (496 reviews)
cleanliness Experience the thrilling casino action at this riverside Cape Girardeau spot.
The price is ¥14,459
¥16,313 total
includes taxes & fees
Feb 16 - Feb 17

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (447 reviews)
cleanliness Stay productive in Sikeston with a modern hotel offering free amenities and fitness.
The price is ¥14,395
¥16,299 total
includes taxes & fees
Feb 8 - Feb 9

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,002 reviews)
cleanliness Experience quiet comfort near restaurants with free breakfast and indoor pool.
The price is ¥13,567
¥15,598 total
includes taxes & fees
Feb 15 - Feb 16

Quality Inn Farmington
Quality Inn FarmingtonFarmington
7.6 out of 10, Good, (867 reviews)
cleanliness Experience outdoor adventures near Wilson Rozier Park from this friendly hotel.
The price is ¥7,953
¥9,495 total
includes taxes & fees
Feb 15 - Feb 16

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (622 reviews)
cleanliness Rest near Charleston with convenient amenities, free breakfast, and parking.
The price is ¥9,612
¥10,666 total
includes taxes & fees
Feb 3 - Feb 4
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Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

Photo by Bill Dillard
Open Photo by Bill Dillard
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Hotels in Southeast Missouri with star-rating

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