
Find hotels in Southeast Missouri, MO from ¥8,910
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Our top choices for Southeast Missouri hotels

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,001 reviews)
The price is ¥17,741
¥20,399 total
includes taxes & fees
Jun 21 - Jun 22

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,006 reviews)
The price is ¥16,447
¥18,554 total
includes taxes & fees
Jun 25 - Jun 26

Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (876 reviews)
The price is ¥15,822
¥17,716 total
includes taxes & fees
Jul 20 - Jul 21

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (921 reviews)
The price is ¥16,287
¥18,401 total
includes taxes & fees
Jun 28 - Jun 29

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (469 reviews)
The price is ¥17,255
¥19,537 total
includes taxes & fees
Jul 19 - Jul 20

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (93 reviews)
The price is ¥17,739
¥20,085 total
includes taxes & fees
Jun 28 - Jun 29

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (786 reviews)
The price is ¥14,941
¥16,169 total
includes taxes & fees
Jun 23 - Jun 24

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (137 reviews)
The price is ¥14,413
¥16,404 total
includes taxes & fees
Jul 1 - Jul 2

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (578 reviews)
The price is ¥16,712
¥18,922 total
includes taxes & fees
Jul 19 - Jul 20

The Farmstead Hotel
The Farmstead HotelCaruthersville
8.6 out of 10, Excellent, (563 reviews)
The price is ¥13,025
¥14,812 total
includes taxes & fees
Jun 22 - Jun 23

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,001 reviews)
The price is ¥15,157
¥16,026 total
includes taxes & fees
Jul 8 - Jul 9

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (520 reviews)
The price is ¥20,174
¥22,860 total
includes taxes & fees
Jul 3 - Jul 4

Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (363 reviews)
The price is ¥15,965
¥17,308 total
includes taxes & fees
Jun 28 - Jun 29

Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (631 reviews)
The price is ¥17,687
¥19,252 total
includes taxes & fees
Jul 21 - Jul 22

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
The price is ¥16,937
¥19,106 total
includes taxes & fees
Jun 25 - Jun 26

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (202 reviews)
The price is ¥14,941
¥16,856 total
includes taxes & fees
Jul 5 - Jul 6

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (601 reviews)
The price is ¥18,240
¥20,578 total
includes taxes & fees
Jun 24 - Jun 25

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis SouthFestus
8.0 out of 10, Very Good, (1,001 reviews)
The price is ¥14,368
¥16,431 total
includes taxes & fees
Jun 22 - Jun 23

Madison Inn Lodge
Madison Inn LodgeFredericktown
7.6 out of 10, Good, (303 reviews)
The price is ¥14,115
¥15,418 total
includes taxes & fees
Jun 22 - Jun 23

Super 8 by Wyndham Perryville
Super 8 by Wyndham PerryvillePerryville
8.4 out of 10, Very Good, (1,000 reviews)
The price is ¥11,377
¥13,024 total
includes taxes & fees
Jun 28 - Jun 29
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Southeast Missouri
Cabin

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (79 reviews)
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Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Walnut Hollow Lake to K Bridge Recreation Area.

Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Jackson MO
10/10 Excellent
More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is ¥10,452 per night from Jun 21 to Jun 22
¥10,452
¥11,376 total
Jun 21 - Jun 22
includes taxes & fees
8/10 Very Good! (1,008 reviews)
Hotels in Southeast Missouri with star-rating

4 Star Hotels
2 properties
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