Find hotels in Southeast Missouri, MO from ￥8,165

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Aug 19 - Aug 20
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Aug 22 - Aug 24
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Compare 585 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Postcard Cabins St. Francois
Exterior

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (27)
"Sweet cabin"
The price is ￥13,100
￥19,639 total
includes taxes & fees
Aug 20 - Aug 21
Postcard Cabins St. Francois
The Farmstead Hotel
Front of property

The Farmstead Hotel

2.5 star property
8.8 out of 10, Excellent, (403)
"Great place. "
The price is ￥12,140
￥13,806 total
includes taxes & fees
Sep 19 - Sep 20
The Farmstead Hotel
Super 8 by Wyndham Farmington
Exterior

Super 8 by Wyndham Farmington

2.0 star property
8.0 out of 10, Very Good, (577)
"Very friendly staff who make sure guests are taken care of! Clean, great location, and safe place to stay. "
The price is ￥8,758
￥9,972 total
includes taxes & fees
Aug 31 - Sep 1
Super 8 by Wyndham Farmington
Drury Inn & Suites Jackson MO
Lobby

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1004)
"We had a last minute reservation here. The staff was very pleasant, helpful and wonderful overall!!"
The price is ￥13,246
￥14,004 total
includes taxes & fees
Aug 26 - Aug 27
Drury Inn & Suites Jackson MO
Baymont Inn and Suites by Wyndham Farmington, MO
Business center

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very Good, (1005)
"Nice stay for the price!"
The price is ￥8,165
￥9,296 total
includes taxes & fees
Sep 1 - Sep 2
Baymont Inn and Suites by Wyndham Farmington, MO
Pear Tree Inn Cape Girardeau West
Lobby

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1006)
"We enjoyed the quick check in and how quiet the property was. "
The price is ￥10,302
￥11,622 total
includes taxes & fees
Aug 20 - Aug 21
Pear Tree Inn Cape Girardeau West
Super 8 by Wyndham Perryville
Exterior

Super 8 by Wyndham Perryville

2.0 star property
8.4 out of 10, Very Good, (898)
" Love the stay and staff was great "
The price is ￥9,429
￥10,794 total
includes taxes & fees
Sep 1 - Sep 2
Super 8 by Wyndham Perryville
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (982)
"Easy access and parking"
The price is ￥13,246
￥14,942 total
includes taxes & fees
Sep 1 - Sep 2
Drury Inn & Suites Cape Girardeau
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Free buffet breakfast

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 star property
9.4 out of 10, Exceptional, (670)
"Love staying at the holiday inn ans suites "
The price is ￥17,453
￥19,959 total
includes taxes & fees
Aug 24 - Aug 25
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Holiday Inn Express & Suites Perryville by IHG
Exterior

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (497)
"Have stayed here the past 3 years during the Laid Back on I-55 Truck Show! Great place to stay! The breakfast is fantastic!! The staff does not disappoint!! "
The price is ￥14,051
￥16,086 total
includes taxes & fees
Aug 31 - Sep 1
Holiday Inn Express & Suites Perryville by IHG
Drury Inn & Suites Hayti Caruthersville
Lobby

Drury Inn & Suites Hayti Caruthersville

3.0 star property
9.4 out of 10, Exceptional, (1002)
"We enjoyed our stay."
The price is ￥13,834
￥15,767 total
includes taxes & fees
Aug 23 - Aug 24
Drury Inn & Suites Hayti Caruthersville
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1003)
"The hotel was very nice and the staff were super helpful. I would stay here again!"
The price is ￥15,161
￥17,103 total
includes taxes & fees
Sep 1 - Sep 2
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Excellent place to stay "
The price is ￥10,302
￥11,622 total
includes taxes & fees
Aug 21 - Aug 22
Pear Tree Inn Cape Girardeau Near the Medical Center
The Riverview
Grand Riverview Two Queen Room | 1 bedroom, premium bedding, pillowtop beds, in-room safe

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (392)
"Nice place to stay! everything was fun and clean."
The price is ￥15,574
￥17,569 total
includes taxes & fees
Aug 20 - Aug 21
The Riverview
Comfort Inn Festus - St Louis South
Lobby sitting area

Comfort Inn Festus - St Louis South

2.5 star property
8.0 out of 10, Very Good, (862)
"Good stay!"
The price is ￥11,441
￥13,368 total
includes taxes & fees
Sep 14 - Sep 15
Comfort Inn Festus - St Louis South
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1011)
"Enjoy my stay here. Very nice room and the breakfast was nice"
The price is ￥13,246
￥14,942 total
includes taxes & fees
Sep 1 - Sep 2
Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Poplar Bluff by IHG
Breakfast, lunch, dinner served; Italian cuisine

Holiday Inn Poplar Bluff by IHG

3.0 star property
8.8 out of 10, Excellent, (671)
"Very clean and comfortable property close to dining options. Would definitely stay again "
The price is ￥14,866
￥16,794 total
includes taxes & fees
Aug 24 - Aug 25
Holiday Inn Poplar Bluff by IHG
Festus Inn
Banquet hall

Festus Inn

2.0 star property
5.6 out of 10, (28)
"Good price and great location. "
The price is ￥13,202
￥15,096 total
includes taxes & fees
Aug 21 - Aug 22
Festus Inn
Drury Inn & Suites Sikeston, MO
Property amenity

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1005)
"Great location "
The price is ￥13,246
￥15,229 total
includes taxes & fees
Aug 24 - Aug 25
Drury Inn & Suites Sikeston, MO
Echo Bluff State Park
Front of property

Echo Bluff State Park

2.5 star property
9.4 out of 10, Exceptional, (207)
"Beautiful location & very friendly staff!"
The price is ￥27,819
￥29,412 total
includes taxes & fees
Sep 3 - Sep 4
Echo Bluff State Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:Aug 29 - Aug 31

Image gallery for Tiny Houses of French Village

House | Living area

Tiny Houses of French Village

2.5 star property
French Village
10/10Exceptional (3 reviews)
10% off
Price is ￥35,942
￥99,104 total
includes taxes & fees
Tiny Houses of French Village
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Stay near popular Southeast Missouri attractions

K Bridge Recreation Area

K Bridge Recreation Area

Explore the great outdoors at K Bridge Recreation Area, a lovely green space in Annapolis. While you're in the area, stroll along the riverfront.

See properties in K Bridge Recreation Area

Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Sam A. Baker State Park to K Bridge Recreation Area.

See all hotels in Southeast Missouri

Top Southeast Missouri Hotel Reviews

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

10/10 Excellent
"This place is amazing. Employees are always friendly and treat you like family not like just another guest. "
Jonathan 1-night trip
Posted 9 hours ago
Motel 6 Poplar Bluff, MO