Find hotels in Serena del Mar, Cartagena

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 27 - Dec 28
Tomorrow
Dec 28 - Dec 29
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Serena del Mar hotels

Restaurant
Varanasi Hotel Boutique

Varanasi Hotel Boutique

Varanasi Hotel Boutique
3.0 star property
Crespo, 8.3 km from Serena del Mar
9.2 out of 10, Wonderful, (581)
"Friendly staff, great stay overall"
United States
April Mafturak
The price is ￥17,995
￥17,995 total
Jan 3 - Jan 4, 2026
Varanasi Hotel Boutique
Outdoor pool, free cabanas, sun loungers
InterContinental Cartagena De Indias by IHG

InterContinental Cartagena De Indias by IHG

InterContinental Cartagena De Indias by IHG
4.0 star property
Bocagrande, 15.3 km from Serena del Mar
9.4 out of 10, Exceptional, (1384)
"Great stay"
United States
Djuan
The price is ￥28,183
￥28,183 total
Jan 24 - Jan 25, 2026
InterContinental Cartagena De Indias by IHG
30-inch flat-screen TV with cable channels, TV
Casa Movida Hostel

Casa Movida Hostel

Casa Movida Hostel
3.0 star property
Cartagena Walled City, 12.5 km from Serena del Mar
8.8 out of 10, Excellent, (179)
"This place is very nice. Highly recommended."
United States
Salvador
The price is ￥10,656
￥10,656 total
Jan 21 - Jan 22, 2026
Casa Movida Hostel
Lobby
Hotel Zuriel Boutique

Hotel Zuriel Boutique

Hotel Zuriel Boutique
3.0 star property
Crespo, 8.1 km from Serena del Mar
9.2 out of 10, Wonderful, (126)
"Good to go"
United States
ONeil
The price is ￥11,079
￥11,079 total
Jan 13 - Jan 14, 2026
Hotel Zuriel Boutique
Outdoor pool
Ermita Cartagena, a Tribute Portfolio Hotel by Marriott

Ermita Cartagena, a Tribute Portfolio Hotel by Marriott

Ermita Cartagena, a Tribute Portfolio Hotel by Marriott
4.0 star property
El Cabrero, 11.4 km from Serena del Mar
9.0 out of 10, Wonderful, (251)
"The staff are amazing. "
United States
Antonio
The price is ￥23,577
￥24,358 total
Jan 27 - Jan 28, 2026
Ermita Cartagena, a Tribute Portfolio Hotel by Marriott
View from room
Hyatt Regency Cartagena

Hyatt Regency Cartagena

Hyatt Regency Cartagena
4.5 star property
Bocagrande, 13.8 km from Serena del Mar
9.4 out of 10, Exceptional, (1433)
"Everything from check in to staff to the food was excellent "
United States
Jerardin L
The price is ￥31,189
￥31,189 total
Jan 21 - Jan 22, 2026
Hyatt Regency Cartagena
View from property
Getsemani Cartagena Luxury Hotel

Getsemani Cartagena Luxury Hotel

Getsemani Cartagena Luxury Hotel
3.5 star property
Getsemani, 12.3 km from Serena del Mar
8.8 out of 10, Excellent, (1003)
"Staff were friendly, room was very clean. The hotel overall is beautiful. Breakfast was excellent. It was amazing to have a Juan Valdez right inside the hotel for the coffee lovers. "
United States
David
The price is ￥14,706
￥14,706 total
Jan 20 - Jan 21, 2026
Getsemani Cartagena Luxury Hotel
Outdoor pool
Palacio del Agua by Faranda Boutique

Palacio del Agua by Faranda Boutique

Palacio del Agua by Faranda Boutique
3.0 star property
Cartagena Centro, 12.9 km from Serena del Mar
10.0 out of 10, Exceptional, (1)
"This was the most beautiful hotel in town! We were the first ones to stay here. The service was excellent and the room was incredible. Super clean, spacious and close to everything in old town Cartagena. We walked everywhere. The staff was amazing! We will definitely come back and stay here again! "
United States
veronica
The price is ￥36,292
￥36,292 total
Jan 26 - Jan 27, 2026
Palacio del Agua by Faranda Boutique
Exterior
Hotel Caribe by Faranda Grand, a member of Radisson Individuals

Hotel Caribe by Faranda Grand, a member of Radisson Individuals

Hotel Caribe by Faranda Grand, a member of Radisson Individuals
5.0 star property
Bocagrande, 15.5 km from Serena del Mar
8.8 out of 10, Excellent, (1001)
"Lodging at Hotel Caribe in the Bocagrande neighborhood of Cartagena de Indias, Colombia."
United States
Andrzej
The price is ￥21,137
￥21,137 total
Jan 13 - Jan 14, 2026
Hotel Caribe by Faranda Grand, a member of Radisson Individuals
Seasonal outdoor pool
Wyndham Garden Cartagena

Wyndham Garden Cartagena

Wyndham Garden Cartagena
3.5 star property
9.2 km from Serena del Mar
8.8 out of 10, Excellent, (1408)
"We would like to thank you for the great service. We really enjoyed our stay."
United States
Acuario
The price is ￥18,737
￥18,737 total
Jan 23 - Jan 24, 2026
Wyndham Garden Cartagena
3 outdoor pools, open 6:00 AM to 10:00 PM, sun loungers
Soy Local Insignia

Soy Local Insignia

Soy Local Insignia
3.0 star property
Getsemani, 12.4 km from Serena del Mar
8.6 out of 10, Excellent, (267)
"Everything was Great. "
United States
Anthony
The price is ￥9,145
￥9,145 total
Jan 21 - Jan 22, 2026
Soy Local Insignia
On the beach, white sand, beach cabanas, sun loungers
Hotel Fenix Beach Cartagena

Hotel Fenix Beach Cartagena

Hotel Fenix Beach Cartagena
4.0 star property
17.8 km from Serena del Mar
8.8 out of 10, Excellent, (604)
"Beach view was amazing and the food options were delicious."
United Kingdom
Alexandra
The price is ￥22,921
￥23,428 total
Jan 7 - Jan 8, 2026
Hotel Fenix Beach Cartagena
Exterior
ibis Cartagena Marbella

ibis Cartagena Marbella

ibis Cartagena Marbella
3.0 star property
Marbella, 10.5 km from Serena del Mar
8.2 out of 10, Very Good, (1006)
"Excellent hotel "
Canada
Nizar
The price is ￥11,043
￥11,043 total
Jan 16 - Jan 17, 2026
ibis Cartagena Marbella
Outdoor spa tub
Múcura Hotel & Spa

Múcura Hotel & Spa

Múcura Hotel & Spa
3.0 star property
8.7 km from Serena del Mar
8.6 out of 10, Excellent, (97)
"Erica at reception was very helpful and made out stay a success. The breakfast was delicious and the ladies who serves were very nice."
United States
Maria
The price is ￥12,859
￥12,859 total
Jan 21 - Jan 22, 2026
Múcura Hotel & Spa
5 outdoor pools, free cabanas, pool umbrellas
Hotel Las Americas Torre del Mar

Hotel Las Americas Torre del Mar

Hotel Las Americas Torre del Mar
4.5 star property
La Boquilla, 6.4 km from Serena del Mar
9.0 out of 10, Wonderful, (1002)
"The rooms were clean, and the staff was courteous. "
United States
Herbert
The price is ￥27,196
￥27,196 total
Jan 26 - Jan 27, 2026
Hotel Las Americas Torre del Mar
Exterior
Holiday Inn Express Cartagena Manga by IHG

Holiday Inn Express Cartagena Manga by IHG

Holiday Inn Express Cartagena Manga by IHG
3.5 star property
Manga, 12.7 km from Serena del Mar
8.8 out of 10, Excellent, (223)
"Excellent Service"
United States
Stephen
The price is ￥16,753
￥16,753 total
Jan 17 - Jan 18, 2026
Holiday Inn Express Cartagena Manga by IHG
Outdoor pool
Hotel Summer Frente Al Mar

Hotel Summer Frente Al Mar

Hotel Summer Frente Al Mar
3.0 star property
Cielo Mar, 6.9 km from Serena del Mar
8.2 out of 10, Very Good, (535)
"A very nice stay "
United States
Adriana
Hotel Summer Frente Al Mar
Outdoor pool, sun loungers
Hotel Boutique La Artillería

Hotel Boutique La Artillería

Hotel Boutique La Artillería
3.0 star property
Getsemani, 12.3 km from Serena del Mar
8.6 out of 10, Excellent, (567)
"Nice Hotel… Very comfortable stay !"
United States
Ronald
The price is ￥12,331
￥12,331 total
Jan 15 - Jan 16, 2026
Hotel Boutique La Artillería
Outdoor pool, sun loungers
Hotel Blue Concept

Hotel Blue Concept

Hotel Blue Concept
2.5 star property
Bocagrande, 15 km from Serena del Mar
8.2 out of 10, Very Good, (369)
"Very comfortable hotel, staff were very friendly , the pool is not so big but overall everything was good "
United States
Ana
Hotel Blue Concept
3 outdoor pools, open 9 AM to 8 PM, pool umbrellas, sun loungers
Sonesta Hotel Cartagena

Sonesta Hotel Cartagena

Sonesta Hotel Cartagena
4.0 star property
La Boquilla, 5.3 km from Serena del Mar
8.0 out of 10, Very Good, (1002)
"Everything looked amazing"
United States
Yely
The price is ￥22,162
￥22,162 total
Jan 20 - Jan 21, 2026
Sonesta Hotel Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Serena del Mar

Find the best Serena del Mar areas and neighborhoods for the activities you enjoy most.
Ayala Center featuring modern architecture

Cartagena Walled City

Cartagena Walled City is known for its ample dining options, and you can make a stop by Clock Tower and Bolivar Square while in the area.

Bocagrande

Boasting the city's most prominent hotels, this upscale area offers shopping at Plaza Bocagrande and Nao Mall, and is close to the popular Ciudad Amurallada. Enjoy various dining options and easy access to the Transcaribe station.

Getsemani

Travelers come to Getsemani for its abundant dining options, and you can see top attractions like Plaza de la Trinidad and Los Pegasos Dock while you're in town.

Cartagena Centro

Unique features of Cartagena Centro include the museums and historic sites. Make a stop by Plaza Santo Domingo or Bolivar Square while you're exploring the area.

El Laguito

The beaches and abundant dining options are top of the list for many visitors to El Laguito. A stop by El Laguito Beach or Bocagrande Beach might round out your trip.

Top Serena del Mar Hotel Reviews

Las Americas Casa de Playa

Las Americas Casa de Playa

10/10 Excellent
"Excellent view "
james 7-night trip
Posted 2 days ago
Las Americas Casa de Playa

Frequently asked questions

What is Serena del Mar like?
Travelers to the Serena del Mar neighborhood in Cartagena will be sure to enjoy their stay.
How many hotels will I be able to find in the Serena del Mar area?
Book one of Expedia's 7 hotels and other accommodations in Serena del Mar and start exploring everything Cartagena has to offer.
If I need to cancel my hotel reservation in Serena del Mar, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best options available in Serena del Mar.
Where can I learn more about changing or cancelling my trip to Serena del Mar?
To find more details about picking new dates or cancelling your trip to Serena del Mar, go to https://www.expedia.com/service/.
What is there to do in this Cartagena neighborhood?
Las Ramblas Shopping Center, Playa Manzanillo, and Karibana Golf Club are just a few of the places to visit in and around Serena del Mar. Make a stop at La Boquilla Beach and Las Americas International Convention Center while you're sightseeing around the area.

Explore a world of travel with Expedia