Top 10 Hotels in Pamplico, SC from ￥6,176 - Competitive Prices

Q: What should I see while I'm in Pamplico?

Places to visit in the wider area include Lions Park , Eastern Carolina Agricultural Fairgrounds , and Florence National Cemetery . You'll also find Florence County Museum and Dr. Eddie Floyd Tennis Center in the area. Check out what more to see and do in Expedia's Pamplico guide .

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Our top choices for Pamplico hotels

An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.

1. The Inn at the Crossroads

Lake City

Winston

￥19,194 total

includes taxes & fees

Dec 10 - Dec 11

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

2. Hyatt Place Florence Downtown

Florence

Delouris

￥20,608 total

includes taxes & fees

Nov 15 - Nov 16

A spacious lobby with a chandelier, seating area, and a reception desk.

3. Quality Inn & Suites Lake City

Lake City

Vajannise

￥15,166 total

includes taxes & fees

Nov 30 - Dec 1

A hotel entrance with a stone facade, glass doors, and a number '501' above.

4. Fairfield Inn & Suites by Marriott Florence I-20

Florence

Alma

￥20,971 total

includes taxes & fees

Nov 12 - Nov 13

A Holiday Inn Express & Suites hotel with a covered entrance, multiple windows, and a parking lot.

5. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Florence

Christopher

￥23,935 total

includes taxes & fees

Dec 8 - Dec 9

A restaurant with brick walls, framed awards, and a bar area.

6. Hotel Florence, Tapestry Collection by Hilton

Florence

WILLIE

￥24,597 total

includes taxes & fees

Nov 15 - Nov 16

A hotel lobby with a reception desk, seating area, and a television screen.

7. Comfort Inn & Suites Florence Center Area

Florence

Steven

￥17,954 total

includes taxes & fees

Nov 29 - Nov 30

A spacious lobby with a large seating area, a decorative ceiling light, and a view of the outdoors.

8. Days Inn by Wyndham Lake City

Lake City

BRIANNA

￥17,350 total

includes taxes & fees

Nov 14 - Nov 15

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

9. Howard Johnson by Wyndham Florence

Florence

Carl

￥11,466 total

includes taxes & fees

Nov 10 - Nov 11

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

10. TownePlace Suites by Marriott Florence

Florence

Ralph

￥19,462 total

includes taxes & fees

Nov 10 - Nov 11

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

11. Park Inn by Radisson Florence, SC

Florence

Susan

￥16,019 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor patio area with wicker furniture, a wooden pergola, and a barbecue setup.

12. Homewood Suites by Hilton Florence

Florence

Delita

￥18,167 total

includes taxes & fees

Nov 22 - Nov 23

13. Home2 Suites by Hilton Florence, SC

Florence

Emily

￥21,159 total

includes taxes & fees

Nov 15 - Nov 16

A hotel entrance with a covered walkway, a brick pathway, and a well-maintained garden.

14. Staybridge Suites Florence - Civic Center by IHG

Florence

Zachary

￥21,656 total

includes taxes & fees

Dec 6 - Dec 7

A hotel entrance with a covered walkway, columns, and a number '340' sign.

15. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Florence

HANH

￥20,235 total

includes taxes & fees

Nov 22 - Nov 23

A multi-story hotel with a prominent entrance and signage for Springhill Suites by Marriott.

16. SpringHill Suites by Marriott Florence

Florence

Tom

￥19,154 total

includes taxes & fees

Nov 11 - Nov 12

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

17. Hampton Inn & Suites Florence Center

Florence

NOORUDIN

￥20,216 total

includes taxes & fees

Nov 15 - Nov 16

A spacious lobby with a reception desk, seating area, and large windows.

18. Hilton Garden Inn Florence

Florence

Maria

￥20,216 total

includes taxes & fees

Nov 15 - Nov 16

A modern hotel with a covered entrance, large windows, and a sign indicating it is a hotel.

19. Aloft by Marriott Florence

Florence

Darlene

￥17,839 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

20. Tru by Hilton Florence I-95

Florence

Margarita

￥20,406 total

includes taxes & fees

Nov 15 - Nov 16

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A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

Hampton Inn & Suites Florence-North-I-95

Florence

10/10 Excellent

I chose Hampton Inn in Florence because, overall, in the past I have had excellent experiences with this chain. I was very pleasantly treated to a very beautifully appointed hotel setting, it was also very clean. I saw staff picking up small items or pieces of paper that had been left or dropped by a visitor. My room itself was very clean and the bed was very comfortable and the room had it's own thermostat so the temperature and whether you wished heat or air could be selected for...

Anonymous traveler

A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

Residence Inn Marriott Florence

Florence

10/10 Excellent

Staff were friendly and nice! Very accommodating to both my dogs. Room was clean and nice. Some wallpaper was bubbling but it honestly didn’t bother me. Loved the secure easy access to the building. Hotel was right next to a beautiful memorial park and very easy to get to the civic center. Pool was beautiful even though I didn’t get to use it due to weather. Looked like the pool was handicap accessible with a lift. Breakfast was amazing every morning with lots to choose from. We definitely will...

Cynthia

Frequently Asked Questions

What are some of the best vacation rentals that Pamplico has to offer?

Stunning historic home w/ large rooms. Close to attractions. Kid & pet friendly!: You might want to consider this vacation home rental near Pamplico, which is located on a lake and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in Pamplico.

If I need to cancel my hotel reservation in Pamplico, will I receive a refund?

Yes, most room reservations are refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Pamplico.

Where can I learn more about changing or cancelling my trip to Pamplico?

To find more details about rescheduling or cancelling your trip to Pamplico, click here.

What's the best accommodation near Florence Regional Airport (FLO)?

Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular 3-star hotel featuring a restaurant and an outdoor pool. It's located 2.2 mi (3.5 km) from Florence Regional Airport. Other good choices near the airport include Hotel Florence, an Ascend Hotel Collection Member and Baymont Inn & Suites Florence by Wyndham.

What is staying in Pamplico like?

Visitors are sure to enjoy all that Pamplico has to offer. There are 166 hotels and other accommodations in the surrounding area. Find out more about Pamplico.

What should I see while I'm in Pamplico?

Places to visit in the wider area include Lions Park, Eastern Carolina Agricultural Fairgrounds, and Florence National Cemetery. You'll also find Florence County Museum and Dr. Eddie Floyd Tennis Center in the area. Check out what more to see and do in Expedia's Pamplico guide.

What's the weather like in Pamplico?

The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Pamplico is 53 inches.

What's the best place for a stay in Pamplico?

Located 20.9 mi (33.7 km) from the heart of Pamplico, Park Inn by Radisson Florence, SC is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Howard Johnson by Wyndham Florence and Quality Inn & Suites Florence Civic Center. See all available top hotels, or vacation rentals in Pamplico.

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Find hotels in Pamplico, SC from ￥6,176

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Treat yourself

Be picky

Go beyond your typical stay in Pamplico

Check prices for these dates

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Our top choices for Pamplico hotels

1. The Inn at the Crossroads

2. Hyatt Place Florence Downtown

3. Quality Inn & Suites Lake City

4. Fairfield Inn & Suites by Marriott Florence I-20

5. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

6. Hotel Florence, Tapestry Collection by Hilton

7. Comfort Inn & Suites Florence Center Area

8. Days Inn by Wyndham Lake City

9. Howard Johnson by Wyndham Florence

10. TownePlace Suites by Marriott Florence

11. Park Inn by Radisson Florence, SC

12. Homewood Suites by Hilton Florence

13. Home2 Suites by Hilton Florence, SC

14. Staybridge Suites Florence - Civic Center by IHG

15. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

16. SpringHill Suites by Marriott Florence

17. Hampton Inn & Suites Florence Center

18. Hilton Garden Inn Florence

19. Aloft by Marriott Florence

20. Tru by Hilton Florence I-95

Top Pamplico Hotel Reviews

Hyatt Place Florence Downtown

10/10 Excellent

Frequently Asked Questions

What are some of the best vacation rentals that Pamplico has to offer?

If I need to cancel my hotel reservation in Pamplico, will I receive a refund?

Where can I learn more about changing or cancelling my trip to Pamplico?

What's the best accommodation near Florence Regional Airport (FLO)?

What is staying in Pamplico like?

What should I see while I'm in Pamplico?

What's the weather like in Pamplico?

What's the best place for a stay in Pamplico?

Explore a world of travel with Expedia