Pamplico Vacation Rentals

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Check prices for these dates

In two weeks
Jan 9 - Jan 11
In two months
Feb 20 - Feb 22
In three months
Mar 20 - Mar 22
In four months
Apr 17 - Apr 19

Our top choices for Pamplico vacation rentals

Fridge, microwave, stovetop, coffee/tea maker
Charming Cottage with easy access to local attractions-pet and kid friendly

Cottage in Sellers

Charming Cottage with easy access to local attractions-pet and kid friendly
9.4 out of 10, Exceptional, (18)
"So charming. The hostess is very accommodating and willing. We felt very welcome. All the accoutrements are tasteful. We had plenty of what we needed for our little celebration. Not too far of a skirt to Flo-town for a bite and some dessert. "
United States
Benjamin
The price is ￥14,736
￥30,511 total
includes taxes & fees
Dec 29 - Dec 30
Charming Cottage with easy access to local attractions-pet and kid friendly
Fridge, microwave, oven, stovetop
Peaceful Farm Getaway

Vacation Home in Mullins

Peaceful Farm Getaway
10.0 out of 10, Exceptional, (31)
"Clean comfortable home on a working farm. The McRae’s are wonderful host/hostess! Enjoyed every minute there."
United States
Christopher P.
The price is ￥21,052
￥32,465 total
includes taxes & fees
Dec 29 - Dec 30
Peaceful Farm Getaway
Fridge, microwave, oven, stovetop
Walking distance from one of South Carolina's top Medical centers.

Vacation Home in Florence

Walking distance from one of South Carolina's top Medical centers.
9.8 out of 10, Exceptional, (42)
"The house was beautiful. We would stay there again!!"
United States
Stephanie L.
The price is ￥20,912
￥36,345 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Walking distance from one of South Carolina's top Medical centers.
Exterior detail
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Vacation Home in Florence

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
2.0 star property
10.0 out of 10, Exceptional, (2)
"It was perfect! And the host was the best everrrr I loved every second I will be returning! "
United States
Kimesha C.
The price is ￥33,445
￥41,655 total
includes taxes & fees
Dec 29 - Dec 30
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Exterior
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

Vacation Home in Marion

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
9.0 out of 10, Wonderful, (6)
"It was a great place. "
United States
Cindy N.
The price is ￥31,188
￥91,446 total
includes taxes & fees
Dec 27 - Dec 28
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Fridge, microwave, oven, stovetop
Lovely upscale 3-bedroom Loft apartment downtown Marion

Apartment in Marion

Lovely upscale 3-bedroom Loft apartment downtown Marion
2.0 star property
The price is ￥28,105
￥34,038 total
includes taxes & fees
Dec 29 - Dec 30
Lovely upscale 3-bedroom Loft apartment downtown Marion
Interior
Secret SC Cabin on 100 acres Hot Tub Large Pond

Cabin in Marion

Secret SC Cabin on 100 acres Hot Tub Large Pond
9.6 out of 10, Exceptional, (175)
"We WILL be back to this cute little cabin! It had everything. Only thing better would be more fish in the pond lol thanks for having us!"
United States
Kimberly L.
The price is ￥31,578
￥73,005 total
includes taxes & fees
Dec 28 - Dec 29
Secret SC Cabin on 100 acres Hot Tub Large Pond
Fridge, microwave, oven, stovetop
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Vacation Home in Florence

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
10.0 out of 10, Exceptional, (37)
"I would definitely stay again! Great location."
United States
LaDara D.
The price is ￥32,436
￥41,044 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pamplico Hotel Reviews

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

10/10 Excellent
"Clean rooms, very convenient location, parking nearby. Very courteous staff. "
Costas 1-night trip
Posted 1 day ago
Hyatt Place Florence Downtown

Find out more about Pamplico

Search for holiday rentals in Pamplico on Expedia! You can easily find your home rentals, villas, holiday apartments in Pamplico using one of the methods below:

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Look no further and take a look at our great range of rental properties in Pamplico!

Frequently asked questions

Are there vacation rentals in Pamplico?

Yes, we give you a choice of vacation rentals near top sights in Pamplico, or you can go with a secluded option if you're looking for relaxation.

What are some of the best vacation rentals in Pamplico?

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington: This vacation home rental near Pamplico offers a fireplace, a hot tub, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a stovetop, and a microwave.

What’s there to see and do in Pamplico?

While you're exploring the area, Greenwood Baseball Park and Playground and Lions Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Eastern Carolina Agricultural Fairgrounds and Francis Marion University.

What’s a vacation rental in Pamplico like?

Vacation rentals are private properties you can stay in for several days or longer in Pamplico. Vacation rentals offer amenities like laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of privacy away from public hotel elevators and lobbies packed with people while still allowing you a great travel experience. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive choice for a family getaway.