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Compare 358 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Florence hotels

Affordable Suites Florence

2.5 star property
9.2 out of 10, Wonderful, (110)
"Parking was good and quiet spot"
Affordable Suites Florence

Staybridge Suites Florence - Civic Center by IHG

3.0 star property
9.4 out of 10, Exceptional, (897)
"Great bacon"
The price is ¥19,941
¥22,334 total
includes taxes & fees
Sep 28 - Sep 29
Staybridge Suites Florence - Civic Center by IHG

TownePlace Suites by Marriott Florence

3.0 star property
9.0 out of 10, Wonderful, (654)
"We stayed here for a quick night on a long drive home. The staff was professional and welcoming in the room was perfect."
The price is ¥16,425
¥18,396 total
includes taxes & fees
Oct 5 - Oct 6
TownePlace Suites by Marriott Florence

Hyatt Place Florence Downtown

3.0 star property
8.8 out of 10, Excellent, (1006)
"Great location & staff"
The price is ¥15,351
¥17,194 total
includes taxes & fees
Sep 30 - Oct 1
Hyatt Place Florence Downtown

Park Inn by Radisson Florence, SC

2.5 star property
9.0 out of 10, Wonderful, (2149)
"Great stay"
The price is ¥13,146
¥14,724 total
includes taxes & fees
Sep 28 - Sep 29
Park Inn by Radisson Florence, SC

Residence Inn Marriott Florence

3.0 star property
8.8 out of 10, Excellent, (426)
"The staff and the breakfast was amazing!!"
The price is ¥16,414
¥18,384 total
includes taxes & fees
Oct 1 - Oct 2
Residence Inn Marriott Florence

SpringHill Suites by Marriott Florence

3.0 star property
8.6 out of 10, Excellent, (936)
"Great place to stay. "
The price is ¥16,696
¥18,700 total
includes taxes & fees
Sep 28 - Sep 29
SpringHill Suites by Marriott Florence

Comfort Inn & Suites

2.5 star property
9.2 out of 10, Wonderful, (1087)
"Very comfortable beds"
The price is ¥14,159
¥15,857 total
includes taxes & fees
Sep 28 - Sep 29
Comfort Inn & Suites

Hotel Florence, Tapestry Collection by Hilton

3.0 star property
8.8 out of 10, Excellent, (583)
"Very unique property. Great room and bath. No closet but didn’t miss it. It had a hanging trolley. Vicytors restaurant is superb. Staff is more than gracious. "
The price is ¥19,335
¥21,656 total
includes taxes & fees
Oct 2 - Oct 3
Hotel Florence, Tapestry Collection by Hilton

Holiday Inn Express & Suites Latta by IHG

2.5 star property
9.4 out of 10, Exceptional, (512)
"Great place to stay "
The price is ¥17,270
¥18,826 total
includes taxes & fees
Oct 19 - Oct 20
Holiday Inn Express & Suites Latta by IHG

Aloft Florence

3.0 star property
8.4 out of 10, Very Good, (193)
"Great hotel"
The price is ¥17,430
¥19,523 total
includes taxes & fees
Sep 28 - Sep 29
Aloft Florence

Fairfield Inn & Suites by Marriott Florence I-20

2.5 star property
9.0 out of 10, Wonderful, (508)
"Great rest stop"
The price is ¥16,414
¥18,384 total
includes taxes & fees
Oct 6 - Oct 7
Fairfield Inn & Suites by Marriott Florence I-20

Homewood Suites by Hilton Florence

3.0 star property
8.4 out of 10, Very Good, (642)
"Front desk hosts were very nice and helpful."
The price is ¥18,047
¥20,796 total
includes taxes & fees
Oct 7 - Oct 8
Homewood Suites by Hilton Florence

The Mantissa Hotel

3.0 star property
9.2 out of 10, Wonderful, (261)
"Excellent stay"
The price is ¥22,015
¥24,657 total
includes taxes & fees
Oct 5 - Oct 6
The Mantissa Hotel

Hampton Inn & Suites Florence-North-I-95

2.5 star property
9.0 out of 10, Wonderful, (746)
"Enjoyed our stay"
The price is ¥16,813
¥18,831 total
includes taxes & fees
Oct 1 - Oct 2
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Hartsville

2.5 star property
9.2 out of 10, Wonderful, (465)
"The staff is very helpful and respectful. A wonderful place to stay..I will be back soon 😊"
The price is ¥17,911
¥20,059 total
includes taxes & fees
Sep 28 - Sep 29
Hampton Inn & Suites Hartsville

Home2 Suites by Hilton Florence, SC

3.0 star property
8.2 out of 10, Very Good, (1006)
"We stay frequently with our dogs and find it to be the best in Florence. "
The price is ¥16,824
¥18,842 total
includes taxes & fees
Oct 5 - Oct 6
Home2 Suites by Hilton Florence, SC

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 star property
9.2 out of 10, Wonderful, (1006)
"Easy drive right off the interstate. Good dining options nearby."
The price is ¥18,021
¥20,183 total
includes taxes & fees
Sep 28 - Sep 29
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Fairfield Inn by Marriott Hartsville

2.5 star property
8.6 out of 10, Excellent, (659)
"Walking distance to restaurants and bar, quiet area, comfortable beds"
The price is ¥15,155
¥16,974 total
includes taxes & fees
Oct 17 - Oct 18
Fairfield Inn by Marriott Hartsville

Howard Johnson by Wyndham Florence

2.0 star property
8.8 out of 10, Excellent, (2367)
"This is a really nice hotel. Thought the room was like perfect quite honestly and I would definitely stay here again"
The price is ¥10,517
¥11,780 total
includes taxes & fees
Oct 7 - Oct 8
Howard Johnson by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Florence and related destinations

Stroll through the West Broad Street Historic District to soak up local history before exploring the Florence Museum's diverse exhibits. Catch a show at the Florence Civic Center or hunt for bargains at Magnolia Mall for a taste of modern entertainment.

Top Florence Hotel Reviews

More cheap stays in Florence

More cheap stays in Florence

Frequently asked questions

What's the best place to stay in Florence?

Staybridge Suites Florence - Civic Center by IHG is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Reviews from our site also recommend Fairfield Inn & Suites by Marriott Florence I-20 and Comfort Inn & Suites as top options for your trip. See all available top hotels, or vacation rentals in Florence.

What's the top vacation rental that Florence has to offer?

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's: This highly rated vacation home rental in Florence is equipped with a fireplace, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Some other top choices in Florence are Jacqueline Estates and Walking distance from one of South Carolina's top Medical centers.. See all vacation rentals in Florence.

If I need to cancel my hotel reservation in Florence, will I receive a refund?

Yes, you'll find most hotel reservations are refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Florence.

Where can I learn more about changing or cancelling my trip to Florence?

For more details about rescheduling or cancelling your trip to Florence, head over to our customer service page.

What's the best budget-friendly accommodation in Florence?

Based on reviews, Park Inn by Radisson Florence, SC is a popular hotel for our travelers who want a more economical choice, and features free buffet breakfast and free WiFi. Other good choices to stay on the cheap include La Quinta Inn & Suites by Wyndham Florence and Howard Johnson by Wyndham Florence. View all budget hotels in Florence.

What's the best place to stay for a family trip to Florence?

La Quinta Inn & Suites by Wyndham Florence is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families. Other good options for your family trip include Howard Johnson by Wyndham Florence and Aloft Florence. Find more child-friendly accommodations in Florence.

What is the favorite LGBTQ-friendly accommodation in Florence?

TownePlace Suites by Marriott Florence is a top LGBTQ-friendly hotel that features free breakfast and free parking. Tru by Hilton Florence I-95 and Courtyard by Marriott Florence are other good choices for your vacation. See all available hotels listed as LGBTQ-friendly in Florence.

What's the best pet-friendly accommodation in Florence?

Park Inn by Radisson Florence, SC is a top hotel for people traveling with their pets, and offers a 24-hour fitness center and free WiFi for its human guests. Other good choices for you and your pet include Comfort Inn & Suites and La Quinta Inn & Suites by Wyndham Florence. See more pet-friendly hotel accommodations in Florence.

Where is the best place to stay with easy access to Florence Civic Center?

Adjacent to Florence Civic Center, Home2 Suites by Hilton Florence, SC is one of the top choices for your stay based on our traveler data, and this 3-star aparthotel offers free breakfast and an indoor pool. Other good options close by include Homewood Suites by Hilton Florence and Comfort Inn & Suites.

What about the best place to stay close to Magnolia Mall?

One of the top choices for your stay is Red Roof Inn Florence - Civic Center, located next to Magnolia Mall, and this hotel offers free parking and free WiFi. Home2 Suites by Hilton Florence, SC and Homewood Suites by Hilton Florence are two other good choices in the immediate area.

What are some accommodations with pools in Florence?

Hyatt Place Florence Downtown is a top hotel with an outdoor pool, free breakfast, and free WiFi. A couple of other options that offer an onsite pool include Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG and Homewood Suites by Hilton Florence. View all hotels with pools in Florence.

What is the best spa hotel in Florence?

Hotel Florence, Tapestry Collection by Hilton is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Enjoy a facial, detox wrap, or Swedish massage at the onsite spa. See all spa hotels in Florence.

What is the best accommodation for staying close to Florence Regional Airport (FLO)?

Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular 3-star hotel featuring a restaurant and an outdoor pool. It's located 2.2 mi (3.5 km) from Florence Regional Airport. Other good choices near the airport include Hotel Florence, an Ascend Hotel Collection Member and Baymont Inn & Suites Florence by Wyndham.

What is staying in Florence like?

Families will find kid-friendly activities in Florence, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its entertainment choices. In Florence, there are 100 hotels and other accommodations to choose from. Find out more about Florence.

What should I see while I'm in Florence?

Landmarks like Mcleod Regional Medical Center, Florence National Cemetery, and Florence Veterans Park might be worth a visit. The picturesque setting of Palmetto Shores Lake and Greenwood Baseball Park and Playground exemplify the area's natural beauty. A couple of additional sights to add to your agenda are Florence Museum and Magnolia Mall. Check out what more to see and do in Expedia's Florence guide.

What's the best way to get around Florence?

If you want to venture outside of the area, hop aboard a train at Florence Station. If you want to venture out around the area, you may want a rental car in Florence for your journey.

What's the weather like in Florence?

The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.

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