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Our top choices for Florence hotels

Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1179)
Located near Florence Veterans Park and Magnolia Mall, this welcoming hotel offers free breakfast and WiFi. Guests love the comfortable beds and can enjoy the 24-hour fitness center or seasonal outdoor pool after exploring nearby attractions.
"Great location, friendly staff. "
United States
Defelicio
The price is ￥15,425
￥17,275 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Comfort Inn & Suites Florence Center Area
Exterior
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2214)
Experience comfort and convenience at this Florence hotel, just minutes from the train station. Enjoy a daily buffet breakfast, free WiFi, and well-equipped fitness center. Nearby attractions include Dr. Eddie Floyd Tennis Center and Palmetto Shores Lake.
"Clean room and friendly staff!"
United States
Daria
The price is ￥13,246
￥14,837 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Park Inn by Radisson Florence, SC
Exterior
Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.6 out of 10, Exceptional, (535)
Enjoy complimentary full breakfast each morning before exploring this charming South Carolina destination. Free parking adds convenience while the helpful staff ensures a pleasant stay. Clean, comfortable rooms provide the perfect retreat after a day of adventure.
"The staff was great and the room was very clean"
United States
Mark Whitehurst
The price is ￥17,536
￥19,115 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Latta by IHG
Exterior
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
8.0 out of 10, Very Good, (1675)
Located in a prime spot near highways and restaurants, this welcoming hotel offers free breakfast, WiFi, and parking. The seasonal outdoor pool and fitness center enhance your stay while the peaceful atmosphere ensures relaxation after exploring nearby attractions.
"Staff was great, breakfast was well stocked "
United States
constance
The price is ￥14,639
￥16,397 total
includes taxes & fees
Dec 30 - Dec 31
La Quinta Inn & Suites by Wyndham Florence
Lobby
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2526)
Enjoy a serene experience at this motel with minimal noise in all rooms. Located within a 15-minute drive of Darlington Raceway, with free breakfast, WiFi, and parking. The helpful staff and convenient access to restaurants earn praise from travelers.
"Great room and staff."
United States
LEE
The price is ￥9,864
￥11,049 total
includes taxes & fees
Dec 30 - Dec 31
Howard Johnson by Wyndham Florence
Front of property - evening/night
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1004)
Embrace comfort in this downtown Florence hotel with an outdoor pool, restaurant, and 24-hour fitness center. Just 5 minutes from Florence Regional Airport and a 16-minute walk to Florence Station, you'll find sofa beds and refrigerators in each clean, well-appointed room.
"Great experience in a nice hotel in downtown."
United States
HATIM
The price is ￥15,657
￥17,536 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hyatt Place Florence Downtown
Exterior
Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (934)
Enjoy convenient amenities at this Florence hotel featuring an outdoor pool and children's pool. The restaurant serves tasty meals, while rooms include refrigerators and microwaves. Located close to Regal Swamp Fox and Florence Veterans Park with free WiFi and parking.
"Great front desk Room was spotless "
United States
Lawrence
The price is ￥21,137
￥23,672 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Staybridge Suites Florence - Civic Center by IHG
Reception
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (826)
"My go to stay while in Fairfax. "
United States
Gregory
The price is ￥15,278
￥17,112 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hampton Inn & Suites Florence Center
Terrace/patio
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1002)
This Florence hotel offers convenience with an indoor pool, fitness center, and in-room refrigerators. Just 15 minutes from Darlington Raceway and close to Palmetto Shores Lake, guests appreciate the helpful staff, clean rooms, and complimentary parking.
"We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. "
United States
Marita
The price is ￥14,636
￥16,940 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Tru by Hilton Florence I-95
Front of property
Best Western Inn

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.6 out of 10, Good, (1004)
Serene atmosphere and helpful staff make this Florence hotel an ideal base. Enjoy the seasonal outdoor pool, free continental breakfast, and easy access to Dr. Eddie Floyd Tennis Center. Just 9 minutes from Florence Regional Airport with complimentary WiFi and parking.
"very clean and quiet"
United States
Marissa
The price is ￥13,935
￥15,608 total
includes taxes & fees
Dec 30 - Dec 31
Best Western Inn
View from property
Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
2.5 star property
Florence
9.0 out of 10, Wonderful, (560)
Conveniently located near Florence Veterans Park and Magnolia Mall, this hotel offers free breakfast and WiFi. The indoor pool provides year-round relaxation, while the attentive staff ensures a pleasant stay for business travelers.
"Clean room, professional and courteous staff. "
United States
Felicia
The price is ￥17,168
￥19,227 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Fairfield Inn & Suites by Marriott Florence I-20
View from property
Residence Inn Marriott Florence

Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
Florence
8.8 out of 10, Excellent, (489)
Enjoy the outdoor pool at this hotel close to Florence Veterans Park and Magnolia Mall. The fitness center keeps workouts on track, while free parking, WiFi, and breakfast add value. Business travelers appreciate the convenient location and helpful staff.
"Yes our stay was great big variety on breakfast clean hotel rooms nice to have a kitchen had a great day"
United States
Marialinda
The price is ￥15,532
￥17,397 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Residence Inn Marriott Florence
Indoor pool
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1005)
Located in Florence near Regal Swamp Fox and Florence Veterans Park, this welcoming hotel offers a refreshing indoor pool experience. Free breakfast, WiFi, and parking complement the business-friendly amenities and attentive staff that guests consistently praise.
"Very good breakfast & convenient location"
United States
Diedre
The price is ￥17,223
￥19,291 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Free daily on-the-go breakfast
Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence
3.0 star property
Florence
8.4 out of 10, Very Good, (660)
Offering a 24-hour fitness center and complimentary breakfast, this hotel sits conveniently close to Regal Swamp Fox and Florence Veterans Park. Clean rooms, free WiFi and parking complement the exceptional staff service that guests consistently praise.
"Room was great, breakfast was great, people were friendly "
United States
Elizabeth
The price is ￥15,278
￥17,730 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Homewood Suites by Hilton Florence
Lobby sitting area
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very Good, (31)
"Friendly staff and clean environment "
United States
john
The price is ￥15,278
￥17,730 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Spark by Hilton Florence North I-95, SC
Desk, blackout drapes, iron/ironing board, free WiFi
SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
3.0 star property
Florence
8.6 out of 10, Excellent, (976)
Set in a peaceful location near Magnolia Mall and Florence Veterans Park, this hotel offers a tranquil retreat. Enjoy complimentary breakfast, WiFi, and parking, plus in-room refrigerators and sofa beds. The indoor pool, fitness center, and attentive staff create a relaxing atmosphere for business or leisure.
"Room is great, and front desk staff were wonderful"
United States
Caroll
The price is ￥16,861
￥18,884 total
includes taxes & fees
Jan 7 - Jan 8, 2026
SpringHill Suites by Marriott Florence
Premium bedding, in-room safe, desk, iron/ironing board
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
7.8 out of 10, Good, (1262)
This quiet Florence hotel offers a seasonal outdoor pool and fitness center near Magnolia Mall. Comfortable beds and helpful staff enhance the relaxing experience, while free breakfast, WiFi, and parking add value. Numerous restaurants within walking distance make dining convenient.
"Room was spotless and the staff was friendly..."
United States
Randy
The price is ￥12,338
￥13,819 total
includes taxes & fees
Jan 28 - Jan 29, 2026
Quality Inn & Suites Florence Civic Center
Exterior
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (826)
Located just 10 minutes from Florence Regional Airport, this welcoming hotel offers free breakfast and parking. Unwind in the hot tub after working out in the fitness center, or enjoy a refreshing drink at the coffee shop. Palmetto Shores Lake and tennis center are nearby attractions.
"We had our dog and the room was good and dog amenities helpful."
United States
Cynthia
The price is ￥17,937
￥20,090 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Hampton Inn & Suites Florence-North-I-95
Exterior
The Inn at the Crossroads

The Inn at the Crossroads

The Inn at the Crossroads
2.0 star property
Lake City
9.4 out of 10, Exceptional, (833)
Enjoy a peaceful stay at this quiet hotel near Lake City's shopping and dining spots. Complete with 24-hour fitness center, American cuisine at Lake City Bistro, and convenient amenities like free breakfast, WiFi, and parking. The helpful staff ensures a comfortable experience.
"Awesome hotel stay "
United States
Jerry
The price is ￥18,057
￥20,223 total
includes taxes & fees
Jan 20 - Jan 21, 2026
The Inn at the Crossroads
Lobby
Best Western Executive Inn

Best Western Executive Inn

Best Western Executive Inn
2.5 star property
Latta
8.2 out of 10, Very Good, (938)
Located in a tranquil area, this hotel offers a refreshing indoor pool and fitness center for active travelers. Enjoy convenient amenities like free breakfast, WiFi and parking. Just 22 minutes from Florence Regional Airport and praised for clean accommodations.
"Would definitely stay again !!!"
United States
Tracy
The price is ￥11,976
￥13,055 total
includes taxes & fees
Jan 22 - Jan 23, 2026
Best Western Executive Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Great weekend hotel deals in Florence, SC

Showing deals for:Jan 9 - Jan 11

Image gallery for Stunning historic home w/ large rooms. Close to attractions. Kid & pet friendly!

Fridge, microwave, oven, stovetop

Stunning historic home w/ large rooms. Close to attractions. Kid & pet friendly!

Sellers
10/10Exceptional (18 reviews)
10% off
Price is ￥42,274
￥154,107 total
includes taxes & fees
Stunning historic home w/ large rooms. Close to attractions. Kid & pet friendly!
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Stay near popular Florence attractions

Florence_FlorenceCivicCenter_6165605_0005

Florence Civic Center

4.0/5 (308 reviews)
The Florence Center hosts everything from electrifying concerts to expansive trade shows in its modern South Carolina venue. Arrive early to navigate security and enjoy the state-of-the-art facilities.
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Florence_MagnoliaMall_6165602_0005

Magnolia Mall

4.0/5 (410 reviews)
This spacious retail hub at the crossroads of two major interstates is Florence's premier shopping destination. Browse national retailers, enjoy diverse dining, or entertain the family at Tilt Studio.
See properties

Florence and related destinations

Stroll through the West Broad Street Historic District to soak up local history before exploring the Florence Museum's diverse exhibits. Catch a show at the Florence Civic Center or hunt for bargains at Magnolia Mall for a taste of modern entertainment.

See all hotels in Florence
Wyche Pavilion Greenville South Carolina

Top Florence Hotel Reviews

Residence Inn Marriott Florence

Residence Inn Marriott Florence

10/10 Excellent
"Staff was very friendly The room Is spacious and very clean . There is plenty of green space outside for our dog !"
Harriet 1-night trip
Posted 2 days ago
Residence Inn Marriott Florence

More cheap stays in Florence

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
The price is ￥9,864 per night from Dec 30 to Dec 31
￥9,864
￥11,049 total
Dec 30 - Dec 31
includes taxes & fees
8.6/10 Excellent! (2,506 reviews)

Frequently asked questions

What's the best place to stay in Florence?
Staybridge Suites Florence - Civic Center by IHG is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Reviews from our site also recommend Fairfield Inn & Suites by Marriott Florence I-20 and Comfort Inn & Suites Florence Center Area as top options for your trip. See all available top hotels, or vacation rentals in Florence.
What's the top vacation rental that Florence has to offer?
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington: This highly rated vacation home rental in Florence offers a fireplace, a hot tub, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a stovetop, and a microwave. Some other top choices in Florence are Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's and Perfect Get-Away In The Heart Of Downtown Florence. See all vacation rentals in Florence.
If I need to cancel my hotel reservation in Florence, will I receive a refund?
Yes, you'll find most hotel reservations are refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Florence.
Where can I learn more about changing or cancelling my trip to Florence?
For more details about rescheduling or cancelling your trip to Florence, head over to our customer service page.
What's the best budget-friendly accommodation in Florence?
Based on reviews, Park Inn by Radisson Florence, SC is a popular hotel for our travelers who want a more economical choice, and features free buffet breakfast and free WiFi. Other good choices to stay on the cheap include La Quinta Inn & Suites by Wyndham Florence and Howard Johnson by Wyndham Florence. View all budget hotels in Florence.
What's the best place to stay for a family trip to Florence?
La Quinta Inn & Suites by Wyndham Florence is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families. Other good options for your family trip include Howard Johnson by Wyndham Florence and Aloft Florence. Find more child-friendly accommodations in Florence.
What is the favorite LGBTQ-friendly accommodation in Florence?
TownePlace Suites by Marriott Florence is a top LGBTQ-friendly hotel that features free breakfast and free parking. Tru by Hilton Florence I-95 and Courtyard by Marriott Florence are other good choices for your vacation. See all available hotels listed as LGBTQ-friendly in Florence.
What's the best pet-friendly accommodation in Florence?
Park Inn by Radisson Florence, SC is a top hotel for people traveling with their pets, and offers a 24-hour fitness center and free WiFi for its human guests. Other good choices for you and your pet include Comfort Inn & Suites Florence Center Area and La Quinta Inn & Suites by Wyndham Florence. See more pet-friendly hotel accommodations in Florence.
Where is the best place to stay with easy access to Florence Civic Center?
Adjacent to Florence Civic Center, Home2 Suites by Hilton Florence, SC is one of the top choices for your stay based on our traveler data, and this 3-star aparthotel offers free breakfast and an indoor pool. Other good options close by include Homewood Suites by Hilton Florence and Comfort Inn & Suites.
What about the best place to stay close to Magnolia Mall?
One of the top choices for your stay is Red Roof Inn Florence - Civic Center, located next to Magnolia Mall, and this hotel offers free parking and free WiFi. Home2 Suites by Hilton Florence, SC and Homewood Suites by Hilton Florence are two other good choices in the immediate area.
What are some accommodations with pools in Florence?
Hyatt Place Florence Downtown is a top hotel with an outdoor pool, free breakfast, and free WiFi. A couple of other options that offer an onsite pool include Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG and Homewood Suites by Hilton Florence. View all hotels with pools in Florence.
What is the best spa hotel in Florence?
Hotel Florence, Tapestry Collection by Hilton is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Enjoy a facial, detox wrap, or Swedish massage at the onsite spa. See all spa hotels in Florence.
What is the best accommodation for staying close to Florence Regional Airport (FLO)?
Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular 3-star hotel featuring a restaurant and an outdoor pool. It's located 2.2 mi (3.5 km) from Florence Regional Airport. Other good choices near the airport include Hotel Florence, an Ascend Hotel Collection Member and Baymont Inn & Suites Florence by Wyndham.
What is staying in Florence like?
Families will find kid-friendly activities in Florence, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its entertainment choices. In Florence, there are 109 hotels and other accommodations to choose from. Find out more about Florence.
What should I see while I'm in Florence?
Landmarks like Mcleod Regional Medical Center, Florence National Cemetery, and Florence Veterans Park might be worth a visit. The picturesque setting of Palmetto Shores Lake and Greenwood Baseball Park and Playground exemplify the area's natural beauty. A couple of additional sights to add to your agenda are Florence Museum and Dr. Eddie Floyd Tennis Center. Check out what more to see and do in Expedia's Florence guide.
What's the best way to get around Florence?
If you want to venture outside of the area, hop aboard a train at Florence Station. If you want to venture out around the area, you may want a rental car in Florence for your journey.
What's the weather like in Florence?
The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.

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