Find Luxury Hotels in Florence, SC

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Top Florence Luxury Hotels

The Mantissa Hotel

3.0 star property
9.2 out of 10, Wonderful, (245)
"Enjoyed our stay at the Mantissa! Great roof top bar! Rooms are spacious and very comfy! Nice kitchen too!"
Judy
The price is ¥21,955
¥24,590 total
includes taxes & fees
Jul 22 - Jul 23
The Mantissa Hotel

Days Inn by Wyndham Dillon

2.0 star property
5.4 out of 10, (814)
"This is a great place to stay for a night. The room was clean, sheets laundered, mini fridge clean, however there was mold in the bathroom shower around the floor. "
Vanesse
The price is ¥9,360
¥10,483 total
includes taxes & fees
Jul 24 - Jul 25
Days Inn by Wyndham Dillon

Hotel Florence, Tapestry Collection by Hilton

3.0 star property
8.8 out of 10, Excellent, (574)
"Great staff, extremely comfortable accommodations and love the bar restaurant. "
Richard
The price is ¥19,106
¥21,400 total
includes taxes & fees
Aug 21 - Aug 22
Hotel Florence, Tapestry Collection by Hilton

Days Inn by Wyndham Florence/I-95 North

2.0 star property
6.8 out of 10, (1005)
"VERY clean, nice breakfast, friendly, accommodating people, the most comfortable bed!"
Carolyn
The price is ¥9,107
¥10,199 total
includes taxes & fees
Aug 17 - Aug 18
Days Inn by Wyndham Florence/I-95 North

Baymont Inn & Suites Florence by Wyndham

2.5 star property
5.6 out of 10, (1000)
"My kids and I loved our stay at the Baymont hotel the staff made us feel very comfortable. I would definitely would come back. "
Tiffany
Baymont Inn & Suites Florence by Wyndham

Clarion Inn & Suites

2.5 star property
4.4 out of 10, (274)
"It is just as the images show. Very nice, is very comfortable, clean, I will stay here again!"
Damian
The price is ¥8,726
¥9,774 total
includes taxes & fees
Aug 1 - Aug 2
Clarion Inn & Suites

Red Roof Inn Florence - Civic Center

2.0 star property
6.8 out of 10, (1005)
"Clean rooms, great room service, cable T.V."
Patrick
The price is ¥8,339
¥9,340 total
includes taxes & fees
Jul 24 - Jul 25
Red Roof Inn Florence - Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
6.8 out of 10, (1010)
"Great value for a race weekend . Room comfortable ac unit did great . Had a hand grip to get in and out of tub . Elevator worked well . Could walk to restaurants . Target right there if you needed something."
Steve
The price is ¥9,487
¥10,624 total
includes taxes & fees
Jul 23 - Jul 24
Days Inn by Wyndham Florence Near Civic Center

Quality Inn & Suites

2.5 star property
7.2 out of 10, Good, (707)
"I enjoyed my stay at the Quality Inn. I didn't think it was going to be a nice stay, initially. However, I contacted the office and another microwave was quickly in my room. The breakfast was delicious, albeit the dining area was a bit small for the customers eating. Overall a great experience from check in to check out. The pool was outdoors and enjoyable. "
James
The price is ¥11,763
¥13,174 total
includes taxes & fees
Aug 19 - Aug 20
Quality Inn & Suites

Quality Inn & Suites Florence Civic Center

2.5 star property
7.8 out of 10, Good, (1230)
"This was a great hotel to stop at for a one night break from driving. It was very clean, a bit on the dated side, but comfortable for the amount spent. Breakfast bar had a great variety and the self serve/make waffles were excellent!"
Anonymous traveler
The price is ¥12,647
¥14,165 total
includes taxes & fees
Aug 19 - Aug 20
Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Florence?
Expedia can help you get a flight to Florence, SC (FLO-Florence Regional) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you'd like to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the shopping which Florence is known for.
How many luxury hotels will I be able to find in Florence?
Lie in the lap of luxury during your getaway to Florence in one of Expedia's 20 luxury hotels.
When can I expect good weather in Florence?
Planning for the weather is a good way to make your trip to Florence relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's there to see and do in Florence?
Take in the sights and attractions that Florence offers with a visit to Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you're in the area, you might want to stop by Florence Veterans Park and Florence Civic Center.
How can I get around Florence?
It's easier to get around town in style when you know your options. If you want to venture outside of the area, hop aboard a train at Florence Station.