Florence Vacation Rentals from ￥8,049: Search Short-Term Rentals

Q: What are some of the best vacation rentals in Florence?

Perfect Get-Away In The Heart Of Downtown Florence : Visitors give good reviews to this Florence vacation home rental, which has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a stovetop, and a microwave, so you can cook with friends or family. Our travelers also rate Walking distance from one of South Carolina's top Medical centers. as a favorite home for rent in Florence.

A calm lake surrounded by trees with autumn foliage.

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Our top choices for Florence vacation rentals

A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.

1. The Urban Flats

Florence

￥62,918 total

includes taxes & fees

Nov 24 - Nov 25

A modern kitchen with a flat-screen TV mounted on a wooden backsplash, a built-in oven, and a dining area with a white table.

2. The Pinecone Retreat - Only 1 mile from i95

Latta

Nita S.

￥22,109 total

includes taxes & fees

Nov 24 - Nov 25

A room with a window, a television, and a cabinet.

3. The Sunny Cottage minutes to downtown

Florence

Lowlan B.

￥31,840 total

includes taxes & fees

Dec 13 - Dec 14

A dining area with a wooden table and chairs, a chandelier, and a large mirror on the wall.

4. Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.

Florence

Bonney W.

￥78,348 total

includes taxes & fees

Nov 15 - Nov 16

A spacious living room with a large leather sofa, a coffee table, and a rug. There is a dining area with a table and chairs, and a kitchen area with a countertop and appliances.

5. Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Florence

Taryn S.

￥43,371 total

includes taxes & fees

Nov 23 - Nov 24

A modern kitchen with white cabinetry, a central island, and stainless steel appliances. There is a dining area with a table and chairs, and a cozy seating area with a sofa and a fireplace.

6. Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Florence

jim j.

￥47,402 total

includes taxes & fees

Dec 3 - Dec 4

A green house with a porch and a chimney.

7. Burn Cottage 1840

Society Hill

Rachel H.

￥32,728 total

includes taxes & fees

Nov 16 - Nov 17

A wooden cabin with a balcony overlooking a river, surrounded by trees.

8. Hideaway Haven – A Private Retreat on 100 Acres

Marion

Josh R.

￥75,118 total

includes taxes & fees

Nov 23 - Nov 24

A dining area with a white table, black chairs, a woven basket, and a teal armchair.

9. Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

Marion

Cindy N.

￥90,698 total

includes taxes & fees

Nov 20 - Nov 21

A cozy living room with a sectional sofa, wooden floors, a ceiling fan, and a door with a window.

10. Peaceful Farm Getaway

Mullins

Ron D.

￥32,206 total

includes taxes & fees

Nov 22 - Nov 23

A dining area with a wooden table and bench, a dark wooden dresser, and two wall-mounted paintings.

11. Peaceful Retreat at Crawford Farms – Quiet and Comfortable for Work or Relaxing.

Marion

Mary h.

￥19,845 total

includes taxes & fees

Dec 14 - Dec 15

A wooden sauna with a view of a lake, featuring a central firebox and benches.

12. Horizons Sandhills

Patrick

￥43,678 total

includes taxes & fees

Nov 23 - Nov 24

A white metal archway surrounded by greenery, with a house in the background.

13. The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet

Bennettsville

robert m.

￥11,519 total

includes taxes & fees

Nov 18 - Nov 19

A room with a desk cluttered with papers, a computer, and various items. There are two white doors and a window with blinds.

14. Queen Bed Non-Smoking

Chesterfield, SC

Anonymous traveler

￥11,707 total

includes taxes & fees

Nov 20 - Nov 21

A brick pathway leading to a white building with a porch and a door labeled "Around Entrance."

15. Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.

Camden

Brent U.

￥22,538 total

includes taxes & fees

Nov 28 - Nov 29

A compact kitchen with white cabinets, a wooden countertop, a built-in microwave, and a refrigerator.

16. Pet-Friendly Hunt Country Cottage with Pool on 7.5 Acres

Camden

Paul C.

A kitchen with a wooden island, white cabinetry, and a stainless steel refrigerator.

17. Family Laurinburg Home w/ Private Yard & BBQ

Laurinburg

Daniel B.

￥129,113 total

includes taxes & fees

Nov 15 - Nov 16

A kitchen with white cabinets, a granite countertop, a stainless steel oven, and two wooden bar stools.

18. 12 Acre Pond House in Chesterfield - come fish and paddle board! 2BR 2B

Chesterfield

Michael Z.

￥47,003 total

includes taxes & fees

Dec 13 - Dec 14

A round wooden table with a white lantern, green leaves, and a tray. A dark blue sofa with patterned pillows is in the background.

19. "Cozy 3-Bedroom House in Fabulous Conway – Comfort, AC, and Relaxation Await!"

Conway

Andrea T.

￥56,347 total

includes taxes & fees

Dec 15 - Dec 16

A hotel room with a bed, bedside table, and a window with curtains.

20. 1 King Bed | Non-Smoking

Lugoff

Anonymous traveler

￥10,644 total

includes taxes & fees

Nov 16 - Nov 17

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Find vacation rentals that suit your style

Top Florence Hotel Reviews

A two-story house with a wrap-around porch, brick exterior, and a front entrance with steps.

1912 Bed and Breakfast

Sumter

10/10 Excellent

Sherise L.

A hotel entrance with a covered walkway, a brick pathway, and a well-maintained garden.

Staybridge Suites Florence - Civic Center by IHG

Florence

10/10 Excellent

William

An outdoor patio area with a fire pit, seating, and a covered section with a grill.

TownePlace Suites by Marriott Sumter

Sumter

10/10 Excellent

Shalaqua

A modern bar area with a long counter, multiple bar stools, and pendant lighting.

Springhill Suites by Marriott Cheraw

Cheraw

10/10 Excellent

Darlene E

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

Park Inn by Radisson Florence, SC

Florence

10/10 Excellent

Nichole

A hotel lobby with a reception desk, seating area, and a television screen.

Comfort Inn & Suites Florence Center Area

Florence

10/10 Excellent

Roland

A spacious restaurant with high ceilings, hanging crystal chandeliers, and a variety of seating options including tables and booths.

Hampton Inn & Suites Hartsville

Hartsville

10/10 Excellent

Sean

A modern lobby with a reception desk, comfortable seating areas, and a large screen TV.

SpringHill Suites Sumter

Sumter

10/10 Excellent

Anonymous traveler

A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.

Affordable Suites Florence

Florence

10/10 Excellent

MY CL

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

Hampton Inn & Suites Florence Center

Florence

10/10 Excellent

Shawn

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

TownePlace Suites by Marriott Florence

Florence

10/10 Excellent

Celia

A hotel entrance with a covered walkway, columns, and a number '340' sign.

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Florence

10/10 Excellent

Tammie

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

Hampton Inn & Suites Florence-North-I-95

Florence

10/10 Excellent

I chose Hampton Inn in Florence because, overall, in the past I have had excellent experiences with this chain. I was very pleasantly treated to a very beautifully appointed hotel setting, it was also very clean. I saw staff picking up small items or pieces of paper that had been left or dropped by a visitor. My room itself was very clean and the bed was very comfortable and the room had it's own thermostat so the temperature and whether you wished heat or air could be selected for...

Anonymous traveler

An outdoor patio with wicker furniture, a fire feature, and string lights.

The Mantissa Hotel

Hartsville

10/10 Excellent

Kiana

A hotel entrance with a stone facade, glass doors, and a number '501' above.

Fairfield Inn & Suites by Marriott Florence I-20

Florence

10/10 Excellent

Anonymous traveler

Hyatt Place Sumter / Downtown

Sumter

10/10 Excellent

To avoid the "usual" motel/hotels in close proximity to i 95 corridor, I searched and found this gem of a place about 20 miles off the mainline; it was well worth the extra drive. The hotel was immaculate, appointed beautifully, and staffed with efficient, knowledgeable, and kind folks. My room was the same. I was greatly relieved and did not feel the need to do my usual inspection. I introduced myself by tripping at the entrance due to imbalance of my own making, carrying too many...

Linda

Find out more about Florence

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Frequently Asked Questions

Can I find vacation rentals in Florence?

Yes, we have vacation rentals in Florence close to Eastern Carolina Agricultural Fairgrounds, or you can choose a secluded option if you'd like a relaxing place to stay. Tourists like the array of shops and top-notch restaurants in Florence. You can also check out the entertainment venues while you're visiting.

What are some of the best vacation rentals in Florence?

Perfect Get-Away In The Heart Of Downtown Florence: Visitors give good reviews to this Florence vacation home rental, which has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a stovetop, and a microwave, so you can cook with friends or family. Our travelers also rate Walking distance from one of South Carolina's top Medical centers. as a favorite home for rent in Florence.

How many vacation rentals will I find in Florence?

Choose from 39 Expedia vacation rentals in Florence for a memorable vacation.

What can I see and do in Florence?

Enjoy the outdoors at Palmetto Shores Lake and Florence Veterans Park, or simply take in cultural attractions like Florence County Museum and FMU Performing Arts Center. Other places in town to visit include Dr. Eddie Floyd Tennis Center and Magnolia Mall.

What are vacation rentals like in Florence?

Vacation rentals are privately owned accommodations you can reserve for a couple days or more in Florence. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll have a home away from home. If you're concerned about cleanliness, a vacation rental can provide a sense of privacy away from public hotel elevators and busy concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for a family trip or a small group gathering.

Florence Vacation Rentals

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Florence vacation rentals

1. The Urban Flats

2. The Pinecone Retreat - Only 1 mile from i95

3. The Sunny Cottage minutes to downtown

4. Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.

5. Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

6. Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

7. Burn Cottage 1840

8. Hideaway Haven – A Private Retreat on 100 Acres

9. Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

10. Peaceful Farm Getaway

11. Peaceful Retreat at Crawford Farms – Quiet and Comfortable for Work or Relaxing.

12. Horizons Sandhills

13. The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet

14. Queen Bed Non-Smoking

15. Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.

16. Pet-Friendly Hunt Country Cottage with Pool on 7.5 Acres

17. Family Laurinburg Home w/ Private Yard & BBQ

18. 12 Acre Pond House in Chesterfield - come fish and paddle board! 2BR 2B

19. "Cozy 3-Bedroom House in Fabulous Conway – Comfort, AC, and Relaxation Await!"

20. 1 King Bed | Non-Smoking

Find vacation rentals that suit your style

Top Florence Hotel Reviews

1912 Bed and Breakfast

10/10 Excellent

Find out more about Florence

Frequently Asked Questions

Can I find vacation rentals in Florence?

What are some of the best vacation rentals in Florence?

How many vacation rentals will I find in Florence?

What can I see and do in Florence?

What are vacation rentals like in Florence?