Florence Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
May 29 - May 31
In two months
Jul 10 - Jul 12
In three months
Aug 7 - Aug 9
In four months
Sep 4 - Sep 6

Our top choices for Florence vacation rentals

Microwave, oven, stovetop, dishwasher

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
Hartsville
10.0 out of 10, Exceptional, (12 reviews)
"Very clean, stayed here for work. Would definitely book again if in the area. "
United States
Kacey
The price is ￥11,429
￥24,569 total
includes taxes & fees
May 18 - May 19
Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
1 bedroom, iron/ironing board, travel crib, free WiFi

Charming Cottage with easy access to local attractions-pet and kid friendly

Charming Cottage with easy access to local attractions-pet and kid friendly
Sellers
9.6 out of 10, Exceptional, (25 reviews)
"A great place to stay with our two dogs. We will be back again soon."
United States
Marianne P.
The price is ￥15,001
￥31,059 total
includes taxes & fees
May 19 - May 20
Charming Cottage with easy access to local attractions-pet and kid friendly
Smart TV, books

Peaceful Farm Getaway

Peaceful Farm Getaway
Mullins
10.0 out of 10, Exceptional, (34 reviews)
"Awesome location near family for the holiday. I can’t wait to book again "
United States
sheliars1 ..
The price is ￥21,381
￥33,318 total
includes taxes & fees
May 18 - May 19
Peaceful Farm Getaway
Interior

Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.
Florence
9.8 out of 10, Exceptional, (52 reviews)
"Our third time staying at this home and always have had a great experience. Such a comfy home and very well stocked. Great hosts!"
United States
Kelly W.
The price is ￥21,287
￥36,464 total
includes taxes & fees
May 18 - May 19
Walking distance from one of South Carolina's top Medical centers.
1 bedroom, free WiFi, bed sheets

imperial motel

imperial motel
Mullins
The price is ￥12,858
￥18,860 total
includes taxes & fees
Jun 10 - Jun 11
imperial motel
Outdoor pool

Private Pool house in Mullins

Private Pool house in Mullins
Mullins
9.2 out of 10, Wonderful, (7 reviews)
"Great stay in Mullins. We enjoyed family time at the pool and had everything we needed. "
United States
Carla H.
The price is ￥26,133
￥39,188 total
includes taxes & fees
May 29 - May 30
Private Pool house in Mullins
2 bedrooms, WiFi, bed sheets

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
Hartsville
8.0 out of 10, Very Good, (1 review)
"The stay was fine , with no problems."
United States
Mark H.
The price is ￥10,715
￥23,792 total
includes taxes & fees
May 17 - May 18
Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
Fridge, microwave, oven, stovetop

The Pinecone Retreat - Only 1 mile from i95

The Pinecone Retreat - Only 1 mile from i95
Latta
10.0 out of 10, Exceptional, (2 reviews)
"So comfy and cozy but plenty of room for our family of four!"
United States
Nita S.
The price is ￥17,422
￥22,443 total
includes taxes & fees
May 24 - May 25
The Pinecone Retreat - Only 1 mile from i95
Dining

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Marion
9.0 out of 10, Wonderful, (6 reviews)
"It was a great place. "
United States
Cindy N.
The price is ￥31,676
￥94,776 total
includes taxes & fees
May 17 - May 18
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Interior

Secret SC Cabin on 100 acres Hot Tub Large Pond

Secret SC Cabin on 100 acres Hot Tub Large Pond
Marion
9.6 out of 10, Exceptional, (184 reviews)
"Great location and house and the host was excellent!"
United States
Josh R.
The price is ￥32,145
￥74,662 total
includes taxes & fees
May 24 - May 25
Secret SC Cabin on 100 acres Hot Tub Large Pond
Dining

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Florence
8.6 out of 10, Excellent, (4 reviews)
"Convenient location"
United States
Bonney W.
The price is ￥23,652
￥80,005 total
includes taxes & fees
Jun 15 - Jun 16
Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Interior

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Florence
10.0 out of 10, Exceptional, (53 reviews)
"Beautiful home and the hosts were so accommodating!!"
United States
Judith S.
The price is ￥32,573
￥40,926 total
includes taxes & fees
May 17 - May 18
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Interior

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Florence
9.8 out of 10, Exceptional, (10 reviews)
"It was perfect! And the host was the best everrrr I loved every second I will be returning! "
United States
Kimesha C.
The price is ￥32,573
￥40,926 total
includes taxes & fees
May 17 - May 18
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
2 bedrooms, WiFi, bed sheets

Staying on a working horse farm

Staying on a working horse farm
Rowland
10.0 out of 10, Exceptional, (1 review)
"We loved the serenity of this property! It was we got an opportunity to see the horses and was so quiet! The trailer had everything two horse moving adults can love!! The owners are amazing ! The horses ( 5 of them ) are well taken care of! We had an opportunity to see the horses brought in for the night and let out for the am❤️"
United States
Keith O.
The price is ￥7,919
￥11,864 total
includes taxes & fees
May 24 - May 25
Staying on a working horse farm
Property grounds

The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet

The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet
Bennettsville
9.8 out of 10, Exceptional, (26 reviews)
"Far from the Madding Crowd, this farm property is hidden in a field surrounded by trees. Very quiet."
United States
Anand
The price is ￥8,553
￥13,482 total
includes taxes & fees
May 27 - May 28
The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet
Fridge, microwave, oven, stovetop

Camden Cottage

Camden Cottage
Camden
10.0 out of 10, Exceptional, (61 reviews)
"Needs more stars! Perfect place to stay and owners are fabulous. Clean, spacious, quiet, and private. Its like home. I highly recommend!"
United States
Cass
The price is ￥17,461
￥30,224 total
includes taxes & fees
Jun 3 - Jun 4
Camden Cottage
Smart TV, books

Charming 2-bedroom house with AC, WiFi in the heart of Pembroke

Charming 2-bedroom house with AC, WiFi in the heart of Pembroke
Pembroke
9.8 out of 10, Exceptional, (6 reviews)
"Great location and so much better then staying in a hotel!"
United States
Teresa G.
The price is ￥23,757
￥61,387 total
includes taxes & fees
May 24 - May 25
Charming 2-bedroom house with AC, WiFi in the heart of Pembroke
Property grounds

Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.

Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.
Camden
9.6 out of 10, Exceptional, (5 reviews)
"we did not see or talk directly to the host; the amenities were all in good condition"
United States
George H.
The price is ￥15,680
￥23,770 total
includes taxes & fees
May 17 - May 18
Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.
Fridge, microwave, oven, stovetop

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
Rembert
9.6 out of 10, Exceptional, (34 reviews)
"Would definitely stay here again! This property is very reasonably priced. Host was great in communication. It was just a lovely, peaceful, and safe place to stay! Wish we would have stayed longer! Thank you so very much."
United States
Josh M.
The price is ￥19,287
￥39,382 total
includes taxes & fees
May 18 - May 19
Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
1 bedroom, WiFi, bed sheets

Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE

Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE
Camden
10.0 out of 10, Exceptional, (7 reviews)
"Highly recommend to anyone who is young enough to climb the steps and old enough to appreciate the history of this neighborhood/town. Thoughtfully decorated and very cozy. "
United States
Ivy
The price is ￥19,798
￥32,997 total
includes taxes & fees
May 17 - May 18
Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Florence Hotel Reviews

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

10/10 Excellent
"The property was very nice and in a quiet location while being close to many restaurants and amenities. There is a nice walking trail across from the property. The front desk employee who checked us in was very sweet. The young lady that checked us out was less than friendly and didn't even say thank you! That being said we enjoyed our stay. The hotel was quiet, clean and the breakfast was good. The price was very good too for an overnight stay. I would stay there again if in the area while traveling. "
Francis 1-night trip
Posted 11 hours ago
Comfort Inn & Suites Florence Center Area

Find out more about Florence

Search for holiday rentals in Florence on Expedia! You can easily find your home rentals, villas, holiday apartments in Florence using one of the methods below:

  • View our selection of featured holiday rentals in Florence
  • Use the map to find apartments and other holiday homes in the Florence neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Florence while they last

Look no further and take a look at our great range of rental properties in Florence!

Frequently asked questions

Can I find vacation rentals in Florence?

Yes, we have vacation rentals in Florence close to Eastern Carolina Agricultural Fairgrounds, or you can choose a secluded option if you'd like a relaxing place to stay. Tourists like the array of shops and top-notch restaurants in Florence. You can also check out the entertainment venues while you're visiting.

What are some of the best vacation rentals in Florence?

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.: Visitors give good reviews to this Florence vacation home rental, which has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Other favorite homes for rent in Florence are Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's and Wonderful 2-bedroom house charming ranch style home.

How many vacation rentals will I find in Florence?

Choose from 37 Expedia vacation rentals in Florence for a memorable vacation.

What can I see and do in Florence?

Palmetto Shores Lake and Florence Veterans Park are a couple of scenic spots to enjoy the outdoors, whereas Florence Museum is one of the cultural attractions. Other places in town to visit include Dr. Eddie Floyd Tennis Center and Magnolia Mall.

What are vacation rentals like in Florence?

Vacation rentals are privately owned accommodations you can reserve for a couple days or more in Florence. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll have a home away from home. If you're concerned about cleanliness, a vacation rental can provide a sense of privacy away from public hotel elevators and busy concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for a family trip or a small group gathering.