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Discover 4,700 Mission Bay hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

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Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay
Learn more about Mission Bay
Fisherman\'s Wharf featuring a bay or harbor
Fisherman's Wharf map

Fisherman's Wharf

1 out of top 10 points of interest in this area

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

Union Square which includes a high rise building and a city
Union Square map

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco featuring railway items
Downtown San Francisco map

Downtown San Francisco

6 out of top 10 points of interest in this area

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

South of Market featuring skyline, a city and city views
South of Market map

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill showing a city and street scenes
Nob Hill map

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Top Mission Bay Hotel Reviews

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

10/10 Excellent
"Loved everything. Hotel in very convenient location. Very friendly staff. Clean rooms. "
Pawel 3-night trip
Posted 6 hours ago
Hotel Caza Fisherman's Wharf

Frequently asked questions

What is Mission Bay like?

Travelers will be sure to enjoy their time in San Francisco's Mission Bay neighborhood. Looking for sights you might find in a travel guide about Mission Bay? Consider a visit to Chase Center while you're in the neighborhood.

Where is the best place to stay in Mission Bay?

Based on Expedia customer reviews, LUMA Hotel San Francisco is the highest ranked property in Mission Bay. This hotel is a short 5-minute walk from Oracle Park, and it offers a restaurant and a fitness center.

How many hotels are there in Mission Bay?

When you want to kick up your feet after a day of exploring the sights in San Francisco, you can choose from 14 Expedia hotels and other accommodations in Mission Bay.

If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then filter by "fully refundable" to get the best deals in Mission Bay.

Where can I learn more about changing or cancelling my trip to Mission Bay?

To access more information about changing or cancelling your trip to Mission Bay, head over to our customer service page.

What are the top things to see and do in Mission Bay?

Chase Center, Lefty O'Doul Bridge, and Lucky Strike San Francisco are just a few attractions to check out in Mission Bay. While you're out sightseeing, Pier 39 and Oracle Park are a couple of additional sights to visit in San Francisco.

How can I get around Mission Bay and the greater San Francisco area?

For a quick way to explore the city, catch a ride on metro transit at Mission Rock Station, UCSF/Chase Center Stop, or UCSF Mission Bay Stop. To venture out of town, take a train from San Francisco Station.