Mission Bay Vacations from ¥387,061

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ¥109,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Mission Bay Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Marbella Lane - 3BR Designer Near Valley Fair

Marbella Lane - 3BR Designer Near Valley Fair

¥387,061
per person
Dec 27 - Jan 1
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to San Jose (SJC)
No reviews
 The Huntington Hotel

The Huntington Hotel

Downtown San Francisco
Save 100% on your flight
¥424,139
per person
Nov 26 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Francisco (SFO)
9.4/10 Exceptional! (36 reviews)
1 Hotel San Francisco

1 Hotel San Francisco

Downtown San Francisco
¥435,850
per person
Dec 29 - Jan 4
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Francisco (SFO)
9.2/10 Wonderful! (621 reviews)
Fairmont Heritage Place, Ghirardelli Square

Fairmont Heritage Place, Ghirardelli Square

Fisherman's Wharf
Save 100% on your flight
¥650,570
per person
Dec 29 - Jan 4
found 11 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Francisco (SFO)
9.4/10 Exceptional! (415 reviews)
@ Marbella Lane - SJ Designer Home 3BR Ldry+p

@ Marbella Lane - SJ Designer Home 3BR Ldry+p

¥412,110
per person
Dec 27 - Jan 1
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to San Jose (SJC)
No reviews

Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay
A cityscape with tall buildings, palm trees, and red double-decker buses.

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

3 out of top 10 points of interest in this area

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

A marina with various boats docked, including a yellow and white boat named 'Golden Gate'.

Fisherman's Wharf

1 out of top 10 points of interest in this area

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

A cityscape with a prominent skyscraper, a bridge, and a mix of modern and historic buildings.

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Mission Bay Hotel Deals

LUMA Hotel San Francisco

LUMA Hotel San Francisco

100 Channel Street San Francisco CA
Fully refundableReserve now, pay when you stay
¥40,310
¥47,444 total
Nov 8 - Nov 9
includes taxes & fees
LUMA Hotel San Francisco
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
¥20,692
¥24,353 total
Nov 8 - Nov 9
includes taxes & fees
Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
¥17,763
¥27,419 total
Nov 9 - Nov 10
includes taxes & fees
9/10 Wonderful! (7,705 reviews)
"The facility was great, the staff was very courteous and great to be around. The breakfast was very good. The gas fires outside were terrific. Great location, close to so much activities. We did not have anything we were not happy with,"

Reviewed on Oct 15, 2026

Hotel Riu Plaza Fisherman's Wharf
See all 4,348 properties in Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission Bay vacation package cost?
Custom make your Mission Bay vacation package from as low as ¥387,061. Pick from any combination of hotels, flights and rental cars to build the getaway you've been dreaming of. Be sure to add on a few activities!
How do I get a cheap travel package to Mission Bay?
Bundle your flights and hotels, throw in extras such as activities or a rental car, and save with a Mission Bay vacation package. You won't just pick up big discounts on your adventure — you'll have a world of choice too. When you book with Expedia, you'll have your pick of over 550 airlines and 1,000,000 hotels all over the world. Your next epic adventure begins right here, right now!
Where should I stay in Mission Bay?
A trip to Mission Bay isn't complete without seeing Pier 39 and Alcatraz Island. Reserve a room close by and easily access these popular tourist attractions.
How far in advance should I book my Mission Bay vacation?
Smart travelers often book as early as possible. You can usually compare international fares on Expedia up to 12 months before your flight. If you've left booking to the last minute, fear not. Budget prices sometimes appear just weeks before departure dates.
What does an Expedia Mission Bay travel package include?
Choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can also add on activities and tours. Want to pick your airfare class? That's possible too. The choice is all yours when it comes to putting together your perfect Mission Bay trip.
What should I know before booking a Mission Bay travel package?
You'll pick up great savings when you bundle your flights, hotels and rental cars into a package. Not only that, booking everything in one place makes trip planning much easier. So why waste your time or money? Whether you're organizing an upscale romantic escape or a budget solo adventure, explore our package deals today.
Can I choose my airline with a Mission Bay Expedia vacation package?
You can, and with more than 550 airlines to choose from worldwide, you're not short on choice. Scroll through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Mission Bay vacation package?
Plans can change unexpectedly, so yes, you can. You may be able to cancel and rebook your Mission Bay vacation package for free within 24 hours of booking. For bookings made more than 24 hours ago, you can still make the necessary changes, but your airline, hotel or car rental company may impose a fee. Want more information? Take a look at our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.

Stay near popular Mission Bay attractions

Chase Center

8.8/10 (1,176 reviews)
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its fascinating museums.
See properties

Mission Bay Conference Center at UCSF

Learn about the events happening at Mission Bay Conference Center at UCSF during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its acclaimed art scene.
See properties

PIER 48 - Lot #39

After visiting PIER 48 - Lot #39, make a plan to see the other sights and activities in San Francisco. Amble around this vibrant area's Chinatown, or seek out the local tours.
See properties

Lefty O'Doul Bridge

You can find out about the history of San Francisco with a trip to Lefty O'Doul Bridge. Take in the acclaimed theater scene and beautiful sunsets in this vibrant area.
See properties

Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

¥7,687
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Alcatraz Inside tour with Round trip ferry & Audio App Packages

Alcatraz Inside tour with Round trip ferry & Audio App Packages

¥13,492
per adult
94% of travellers recommend
Alcatraz Inside tour with Round trip ferry & Audio App Packages
San Francisco Sunset Cruise

San Francisco Sunset Cruise

¥6,118
per adult
San Francisco Sunset Cruise
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.