Find Resorts & Hotels with Spas in Little Italy, CA

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Little Italy Resorts & Hotels with Spas

Tonight
Jan 7 - Jan 8
Tomorrow
Jan 8 - Jan 9
This weekend
Jan 9 - Jan 11
Next weekend
Jan 16 - Jan 18

Our top choices for Little Italy hotels with a spa

Exterior
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1597)
"Great staff"
United States
Samuel
The price is ￥22,409
￥34,044 total
includes taxes & fees
Jan 22 - Jan 23
Hyatt Regency Mission Bay Spa and Marina
Hot stone massages, prenatal massages, sports massages, body scrubs
San Diego Mission Bay Resort

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1331)
"Loved the bay front room with the large grass area right out the door!"
United States
Todd and Danielle
The price is ￥23,819
￥35,660 total
includes taxes & fees
Feb 2 - Feb 3
San Diego Mission Bay Resort
Couples treatment rooms, sauna, hot tub, steam room, body treatments
Loews Coronado Bay Resort

Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
Silver Strand
8.8 out of 10, Excellent, (1062)
"The staff and amenities were spectacular. "
United States
Andrew
The price is ￥31,163
￥42,234 total
includes taxes & fees
Jan 8 - Jan 9
Loews Coronado Bay Resort
Couples treatment rooms, body treatments, hot stone massages
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2962)
"Enjoyed my stay. Clean rooms, nice staff, will come back again "
United States
Oscar
Legacy Resort Hotel & Spa
Body treatments, aromatherapy, body wraps, body scrubs, facials
Hilton San Diego Bayfront

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1907)
"Beautiful hotel "
United States
Crystal
The price is ￥28,072
￥40,207 total
includes taxes & fees
Jan 10 - Jan 11
Hilton San Diego Bayfront
Property grounds
Paradise Point Resort & Spa

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.6 out of 10, Excellent, (2376)
"Great facility and amenities. We look forward to taking our family back again. "
United States
Andy
The price is ￥17,268
￥28,136 total
includes taxes & fees
Jan 19 - Jan 20
Paradise Point Resort & Spa
Body treatments, hydrotherapy, aromatherapy, hot stone massages
Westgate Hotel

Westgate Hotel

Westgate Hotel
4.5 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1001)
"Loved this stay, they were very accommodating "
United States
Maurizio
Westgate Hotel
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
National City
9.2 out of 10, Wonderful, (3611)
"The hotel and staff were great. "
United States
Rosa
The price is ￥20,201
￥22,260 total
includes taxes & fees
Jan 8 - Jan 9
Best Western Plus Marina Gateway Hotel
Dinner served
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2065)
"Great room great location"
United States
Ramin
The price is ￥29,601
￥41,402 total
includes taxes & fees
Jan 8 - Jan 9
Omni San Diego Hotel at the Ballpark
Premier Room, 1 King Bed | Premium bedding, in-room safe, desk, blackout drapes
Handlery Hotel

Handlery Hotel

Handlery Hotel
3.5 star property
Mission Valley
8.2 out of 10, Very Good, (2275)
"Room and staff were excellent"
United States
Bryant
Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Little Italy Hotel Reviews

Best Western Seven Seas

Best Western Seven Seas

10/10 Excellent
"Great experience I plan to stay here. "
Esteban 1-night trip
Posted 11 hours ago
Best Western Seven Seas

Frequently asked questions

Looking to vacation at a spa hotel in Little Italy?
Treat yourself to some pampering and book a hotel with a spa. Travelers highly recommend the restaurants in Little Italy. Enjoy the museums and cafes during your vacation. Spa hotels are a great way to take a break from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Little Italy?
When you're in Little Italy, enjoy exploring the sights and attractions here including Maritime Museum of San Diego, San Diego Bay, and Star of India. If you have a little extra time during your trip, you might want to make a stop at San Diego Zoo and Mission Bay.
What is a Little Italy spa hotel?
Spa hotels in Little Italy feature full on-site spas and offer services such as couples massages and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

Explore a world of travel with Expedia