A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
Sep 25 - Sep 26
Tomorrow
Sep 26 - Sep 27
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Key Largo luxury hotels

An aerial view of a resort with a large pool, palm trees, and a beach.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.
A beachside patio with lounge chairs, a table, and a view of the ocean.
A beach with clear water, a wooden pier, and lounge chairs under a tree.

1. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
￥41,625
￥55,553 total
includes taxes & fees
Oct 8 - Oct 9
Playa Largo Resort & Spa, Autograph Collection
A wooden deck with a view of the ocean and a palm tree.
A coconut drink with a straw, a cherry, and a slice of fruit on a table by a pool with a waterfall and palm trees in the background.
A beach bar with a thatched roof, palm trees, and a view of the sea.
A modern hotel room with a large bed, a desk with a lamp, a chair, and a view of the ocean.

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
￥41,508
￥55,421 total
includes taxes & fees
Sep 29 - Sep 30
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A poolside area with blue chairs and a thatched-roof structure.
A spacious living room with large windows, comfortable seating, and decorative plants.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
￥31,496
￥41,765 total
includes taxes & fees
Sep 27 - Sep 28
Reefhouse Resort & Marina
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A resort with multiple white buildings, each featuring balconies and surrounded by lush greenery and palm trees.
A gated entrance to a resort with palm trees and a clear sky.
A pool area with clear blue water, white lounge chairs, and palm trees.

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
￥64,100
￥82,119 total
includes taxes & fees
Oct 1 - Oct 2
The Islands of Islamorada
A balcony with wicker chairs, a small table with drinks, and a view of the beach and ocean.
An outdoor dining area with round tables and chairs, a thatched roof, and a view of the sea.
A resort with a pool, beach, and ocean view.
A beach with palm trees, a clear blue sky, and a calm sea.

5. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
￥32,893
￥48,614 total
includes taxes & fees
Oct 15 - Oct 16
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
A wooden pier leading to a beach with palm trees and a row of beach huts.
A paved pathway leading to a beach with palm trees and a view of the ocean.
A beachside patio with wooden furniture, a thatched roof, and a view of the ocean.

6. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
￥33,510
￥49,307 total
includes taxes & fees
Oct 7 - Oct 8
Islander Resort
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A spacious lobby with a seating area, a bar, and a large window providing a view of the outdoors.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.

7. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
￥21,695
￥35,981 total
includes taxes & fees
Oct 4 - Oct 5
Cheeca Lodge & Spa
A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.
An aerial view of a resort with a swimming pool, palm trees, and a dock.
A resort pool with palm trees, beach chairs, and umbrellas.
A hotel room with a bed, a sofa, a coffee table, a desk with a lamp, and a view of the ocean.

8. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
￥22,820
￥37,282 total
includes taxes & fees
Oct 18 - Oct 19
Amara Cay Resort
View all properties

Top Key Largo Hotel Reviews

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Amando este lugar muchas gracias Yoli por toda la atención volveremos pronto"
isoruma 1-night trip
Posted 10 hours ago
Playa Largo Resort & Spa, Autograph Collection
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Loved it so much my first trip I booked again! This stay was just as great as my last stay. Rooms were beautifully furnished with amazing views. Staff are super friendly- had another great stay! Will be back soon!"
Jacqueline 4-night trip
Posted 13 hours ago
Reefhouse Resort & Marina
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Great location !!"
Jenny 2-night trip
Posted 19 hours ago
Bayside Inn Key Largo
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"The place had character and culture that modern sterile resorts do not."
Wayne 1-night trip
Posted 1 day ago
The Pelican Key Largo Cottages
Azul del Mar

Azul del Mar

10/10 Excellent
"This was a great place to stay"
Loney 1-night trip
Posted 2 days ago
Azul del Mar
Sunset Cove Beach Resort

Sunset Cove Beach Resort

8/10 Good
"Takes pets for reasonable rate; but no pool"
Deborah 2-night trip
Posted 3 days ago
Sunset Cove Beach Resort
Gilbert's Resort

Gilbert's Resort

10/10 Excellent
"What a great place. Rooms were very spacious for our family of 6 and you really feel in the keys with the decor. Swimming pool was nice and the little beach cove is beautiful. The deck and boats around are nice. The restaurant is very nice too. Would stay again."
Anthony 1-night trip
Posted 3 days ago
Gilbert's Resort
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

10/10 Excellent
"Key Largo is one of our favorite places. We try to stay in this Hotel because is a win win. Exceptional front desk, the hotel is clean and the amenities are wonderful. Thankfully."
Lisette 1-night trip
Posted 4 days ago
Marina Del Mar Resort and Marina
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

8/10 Good
"Decent hotel to stay at. Breakfast was pricey, we searched elsewhere to eat. We couldn’t connect to the WiFi in the room the whole week. Their tech tried to help, but no luck. Close to restaurants and sites that we wanted to go visit."
Ann 5-night trip
Posted 6 days ago
Holiday Inn Key Largo by IHG

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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