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Our top choices for Key Largo luxury hotels

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1,001 reviews)
  • cleanliness
    Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
"I enjoyed the spa had a facial with Marlene that was very good as was my message."
United States
Christine
The price is ¥50,778
¥65,902 total
includes taxes & fees
Jun 7 - Jun 8
Playa Largo Resort & Spa, Autograph Collection

Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.4 out of 10, Exceptional, (1,438 reviews)
"Spa was wonderful"
United States
Michelle
The price is ¥34,860
¥45,585 total
includes taxes & fees
Jun 21 - Jun 22
Reefhouse Resort & Marina

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.6 out of 10, Excellent, (1,074 reviews)
  • cleanliness
    Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
"Beautiful, relaxing resort with sandy beaches, great service, and stunning views — a bit pricey but worth it for the luxury and tropical vibe."
United States
ALEJANDRO
The price is ¥44,514
¥58,855 total
includes taxes & fees
Jun 16 - Jun 17
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,312 reviews)
  • cleanliness
    Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
"Loved the stay with two 6 year old boys. There was so much to do on the property we had planned to do more exploring of the keys but found the boys loved being on the dock fishing, on the water kayaking, riding bikes and swimming in the warm pool."
United States
Carol
The price is ¥31,677
¥47,278 total
includes taxes & fees
May 31 - Jun 1
Cheeca Lodge & Spa

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.6 out of 10, Exceptional, (76 reviews)
"Very comfortable and luxurious."
United States
Anze
The price is ¥91,570
¥111,790 total
includes taxes & fees
May 27 - May 28
The Islands of Islamorada

Amara Cay Resort

Amara Cay Resort
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1,274 reviews)
  • cleanliness
    Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
"The other great thing was the resort never felt too busy, making the experience more intimate and luxurious."
United States
Jade
The price is ¥29,556
¥44,892 total
includes taxes & fees
May 27 - May 28
Amara Cay Resort

Islander Resort

Islander Resort
4.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,015 reviews)
  • cleanliness
    Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
"The rooms are consistently comfortable, clean, and beautifully maintained, with lovely views and thoughtful amenities that make our stay special."
United States
francy
The price is ¥39,163
¥54,803 total
includes taxes & fees
Jun 3 - Jun 4
Islander Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
4.0 star property
Islamorada
9.0 out of 10, Wonderful, (198 reviews)
  • cleanliness
    Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
"Love this new resort in my favorite place in Islamorada They have made it a first class experience! Highly recommend. "
United States
Lisa
The price is ¥40,456
¥57,154 total
includes taxes & fees
Jun 10 - Jun 11
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

La Siesta Resort & Villas

La Siesta Resort & Villas
4.0 star property
Matecumbe
8.6 out of 10, Excellent, (1,001 reviews)
"For two people the room was lovely & spacious, with a seperate lounge and dining/kitchen area & a balcony that caught the morning sun."
United Kingdom
Hayley
The price is ¥26,380
¥41,318 total
includes taxes & fees
May 27 - May 28
La Siesta Resort & Villas

Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
4.0 star property
Homestead
9.2 out of 10, Wonderful, (11 reviews)
"The place was amazing, truly a gem. I enjoyed reading my book surrounded by nature. I booked the wrong dates. The team was extremely helpful in getting me reoriented and settled in. I appreciate the flexibility they offered. "
United States
Christine
The price is ¥19,875
¥47,652 total
includes taxes & fees
May 31 - Jun 1
Find Peace - Tiny House in Japanese Garden
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Key Largo Hotel Reviews

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
Known for its sunsets and boating, Key Largo also has some interesting things to see and do including Everglades National Park, so you may want to take in the local sights during your visit.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Everglades National Park, Jimmy Johnson's Big Chill, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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