A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
Oct 6 - Oct 7
Tomorrow
Oct 7 - Oct 8
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Key Largo luxury hotels

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A spacious living room with large windows, comfortable seating, and decorative plants.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A poolside area with blue chairs and a thatched-roof structure.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
￥34,569
￥45,205 total
includes taxes & fees
Oct 8 - Oct 9
Reefhouse Resort & Marina
An aerial view of a resort with a large pool, palm trees, and a beach.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.
A beach with clear water, a wooden pier, and lounge chairs under a tree.
A beachside patio with lounge chairs, a table, and a view of the ocean.

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
￥41,530
￥55,427 total
includes taxes & fees
Oct 19 - Oct 20
Playa Largo Resort & Spa, Autograph Collection
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A gated entrance to a resort with palm trees and a clear sky.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.
A pool area with clear blue water, white lounge chairs, and palm trees.

3. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
￥68,416
￥87,041 total
includes taxes & fees
Oct 14 - Oct 15
The Islands of Islamorada
View all properties

Top Key Largo Hotel Reviews

Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"Great place. We stay here every year"
Pamela 2-night trip
Posted less than an hour ago
Waterside Suites & Marina
Gilbert's Resort

Gilbert's Resort

10/10 Excellent
"Amamos Gilber, el lugar es muy familiar"
Ana milena 1-night trip
Posted 13 hours ago
Gilbert's Resort
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

8/10 Good
"We were not aware and can’t see it on the website that the hotel is under an extensive refurbishment. When we pulled into the front car park it looked like a construction zone. The dining area is cut in half with makeshift plastic sheeting separating the breakfast area and the construction. The second floor rooms are also going through a full makeover just over way down the second section. Bearings with all of this, we actually had a pleasant stay. The construction is quite considerate and the builders quite respectful. The breakfast was quite nice, the renovated rooms of a good standard and the pool / Tiki bar area very good. 5 star luxury it’s not, good basic clean accommodation to explore the Keys it certainly is. Would we go back, yes we would so a thumbs up."
Kevin 3-night trip
Posted 14 hours ago
Hampton Inn Key Largo Manatee Bay
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"All together great"
Joshua 1-night trip
Posted 15 hours ago
The Pelican Key Largo Cottages
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Excellent place"
Manny 4-night trip
Posted 18 hours ago
Reefhouse Resort & Marina
Azul del Mar

Azul del Mar

10/10 Excellent
"Nice"
Mickey 4-night trip
Posted 1 day ago
Azul del Mar
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Exactly the experience we wanted. Great views, great location, fishing off the dock."
Jean-luc 2-night trip
Posted 1 day ago
Bayside Inn Key Largo
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

8/10 Good
"Decent hotel to stay at. Breakfast was pricey, we searched elsewhere to eat. We couldn’t connect to the WiFi in the room the whole week. Their tech tried to help, but no luck. Close to restaurants and sites that we wanted to go visit."
Ann 5-night trip
Posted 3 weeks ago
Holiday Inn Key Largo by IHG

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 4 restaurants and 3 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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