A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
Oct 20 - Oct 21
Tomorrow
Oct 21 - Oct 22
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Key Largo luxury hotels

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A spacious living room with large windows, comfortable seating, and decorative plants.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
￥34,606
￥45,254 total
includes taxes & fees
Oct 22 - Oct 23
Reefhouse Resort & Marina
A laundry room with a washing machine and dryer, white cabinets, and a granite countertop.
A beach with clear water, a wooden pier, and lounge chairs under a tree.
A beachside patio with lounge chairs, a table, and a view of the ocean.
An aerial view of a resort with a large pool, palm trees, and a beach.

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
￥47,880
￥62,577 total
includes taxes & fees
Nov 4 - Nov 5
Playa Largo Resort & Spa, Autograph Collection
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A spacious lobby with a seating area, a bar, and a large window providing a view of the outdoors.
A tropical resort with a swimming pool, palm trees, and a waterfall.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.

3. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
￥24,836
￥39,496 total
includes taxes & fees
Oct 22 - Oct 23
Cheeca Lodge & Spa
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A pool area with clear blue water, white lounge chairs, and palm trees.
A resort with multiple white buildings, each featuring balconies and surrounded by lush greenery and palm trees.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
￥75,888
￥95,603 total
includes taxes & fees
Oct 29 - Oct 30
The Islands of Islamorada
View all properties

Top Key Largo Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

8/10 Good
"The property is beautiful, we had a gorgeous view, loved the walkways and facilities. Great location close to great restaurants, shops, snorkeling and kayaking trips. Our room was not ready until close to 5 p.m. when check-in is supposed to be at 4 p.m. Check-in was not welcoming, and the entire time we were there a dog was permitted to swim in the area where people were swimming."
sophia 2-night trip
Posted 1 hour ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Every employee was very nice, tiki bartender was so friendly, the breakfast was amazing, big room with coffee and refrigerator were nice to have, pool, beach and kayaks were fun. easy parking and access right into the room, can’t wait to come back after the remodel. Sunset from the beach was a highlight."
Perry 1-night trip
Posted 7 hours ago
Hampton Inn Key Largo Manatee Bay
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Staff very friendly and helpful"
TIMOTHY 2-night trip
Posted 8 hours ago
Reefhouse Resort & Marina
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"The hotel was conveniently located, close to all the main attractions in Key Largo, which made it easy to get around. The room was cozy and comfortable. The only downside was that the room was on the second floor, which was a bit inconvenient. Overall, it was a nice stay and a good location for exploring the area."
Daniela 2-night trip
Posted 12 hours ago
Waterside Suites & Marina
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

8/10 Good
"The Pelican was nice. It was a little dated. They have a tiki bar but no bar. I think music would be great when you’re sitting out by the dock. We booked 2 days but left after 1. There is not a whole lot to do around the property. No town to go to for restaurants."
Tina 2-night trip
Posted 14 hours ago
The Pelican Key Largo Cottages
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"Great staff, very comfortable, and wonderful amenities. This property is beautiful and right on the water."
Richard 1-night trip
Posted 1 day ago
Sunset Cove Beach Resort

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 4 restaurants and 3 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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