A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Find Luxury Hotels in Key Largo, FL

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Check availability on Key Largo Luxury Hotels

Tonight
Aug 24 - Aug 25
Tomorrow
Aug 25 - Aug 26
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Our top choices for Key Largo luxury hotels

1. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
¥40,275
¥54,073 total
includes taxes & fees
Sep 21 - Sep 22
Baker's Cay Resort Key Largo, Curio Collection by Hilton

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
¥39,261
¥52,931 total
includes taxes & fees
Sep 20 - Sep 21
Playa Largo Resort & Spa, Autograph Collection

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
¥34,810
¥45,520 total
includes taxes & fees
Aug 25 - Aug 26
Reefhouse Resort & Marina

4. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
¥23,684
¥38,269 total
includes taxes & fees
Aug 27 - Aug 28
Cheeca Lodge & Spa

5. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
¥56,078
¥72,973 total
includes taxes & fees
Aug 25 - Aug 26
The Islands of Islamorada

6. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
¥34,537
¥49,583 total
includes taxes & fees
Sep 2 - Sep 3
Islander Resort

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
¥32,934
¥48,674 total
includes taxes & fees
Aug 31 - Sep 1
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

8. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
¥24,579
¥39,275 total
includes taxes & fees
Aug 30 - Aug 31
Amara Cay Resort

9. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
¥24,570
¥39,265 total
includes taxes & fees
Aug 26 - Aug 27
La Siesta Resort & Villas

10. Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
Homestead
¥17,326
¥44,763 total
includes taxes & fees
Aug 25 - Aug 26
Find Peace - Tiny House in Japanese Garden
View all properties

Top Key Largo Hotel Reviews

Gilbert's Resort

Gilbert's Resort

8/10 Good
"Reviewed the time to be a little more up to date. Not bad, but not what I’m used to from a proper on the water. Great views though"
Princess 1-night trip
Posted 1 hour ago
Gilbert's Resort
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"is really amazing very good and really closed to many restaurants ,you'll love it"
Clara 2-night trip
Posted 4 hours ago
Waterside Suites & Marina
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"Espectacular"
Angélica Maria 1-night trip
Posted 17 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"Excellent service from the cleaning staff and reception; a wonderful place to relax and enjoy days of sun and beach. Easy access to local restaurants. We love it and will return whenever we can—thanks to the entire staff."
luis 3-night trip
Posted 23 hours ago
The Pelican Key Largo Cottages
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Excellent room clean and staff was wonderful pool was perfect and water temp was cool for how warm it is"
Robert 2-night trip
Posted 2 days ago
Playa Largo Resort & Spa, Autograph Collection
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

10/10 Excellent
"Excellent property all the way around. Will be returning next year for sure!!"
Michael 5-night trip
Posted 3 days ago
Holiday Inn Key Largo by IHG

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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