A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Find Luxury Hotels in Key Largo, FL

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Check availability on Key Largo Luxury Hotels

Tonight
Sep 14 - Sep 15
Tomorrow
Sep 15 - Sep 16
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Our top choices for Key Largo luxury hotels

1. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
¥39,171
¥52,537 total
includes taxes & fees
Sep 27 - Sep 28
Playa Largo Resort & Spa, Autograph Collection

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
¥36,402
¥49,422 total
includes taxes & fees
Sep 28 - Sep 29
Baker's Cay Resort Key Largo, Curio Collection by Hilton

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
¥33,641
¥43,991 total
includes taxes & fees
Sep 15 - Sep 16
Reefhouse Resort & Marina

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
¥62,212
¥79,700 total
includes taxes & fees
Sep 21 - Sep 22
The Islands of Islamorada

5. Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
Homestead
¥69,893
¥103,319 total
includes taxes & fees
Sep 15 - Sep 16
Find Peace - Tiny House in Japanese Garden

6. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
¥22,888
¥36,983 total
includes taxes & fees
Sep 15 - Sep 16
Cheeca Lodge & Spa

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
¥28,142
¥42,893 total
includes taxes & fees
Sep 20 - Sep 21
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

8. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
¥32,374
¥46,790 total
includes taxes & fees
Sep 29 - Sep 30
Islander Resort

9. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
¥22,083
¥36,077 total
includes taxes & fees
Sep 21 - Sep 22
Amara Cay Resort
View all properties

Top Key Largo Hotel Reviews

Azul del Mar

Azul del Mar

10/10 Excellent
"I was very happy when I arrived to the hotel. Everything was like brand new and very clean ! The kitchen, which is my favorite part, was spacious and had all the appliances and utensils necessary for my stay. The staff were extremely friendly! I would highly recommend this property if you want to have a relax stay with no issues whatsoever!!"
Celeste 2-night trip
Posted 5 hours ago
Azul del Mar
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"1"
e 1-night trip
Posted 17 hours ago
Waterside Suites & Marina
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"Clean rooms and staff was nice. We really liked the place. Will come back"
Cathy 1-night trip
Posted 23 hours ago
Amoray Dive Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"The hotel is very lovely and cozy, the entire staff is very friendly, and the areas and rooms are very clean; I recommend it."
juan 2-night trip
Posted 1 day ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"It’s the perfect stay for a relaxing beach getaway."
Bonny 1-night trip
Posted 1 day ago
The Pelican Key Largo Cottages
Bayside Inn Key Largo

Bayside Inn Key Largo

8/10 Good
"Clean, overall alright."
Celeuca 3-night trip
Posted 2 days ago
Bayside Inn Key Largo
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"Excellent place!"
Douglas 2-night trip
Posted 2 days ago
Sunset Cove Beach Resort
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

10/10 Excellent
"2 pools and isn’t too far from anywhere"
Abigail 4-night trip
Posted 2 days ago
Holiday Inn Key Largo by IHG
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Super good resorts"
Danilo 2-night trip
Posted 3 days ago
Playa Largo Resort & Spa, Autograph Collection

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Bluefin Rock Harbor Marina, and John Pennekamp Coral Reef State Park. If you have a little extra time during your trip, you might want to make a stop at MarineLab Undersea Laboratory and Caribbean Club Bar.

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