A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
Sep 8 - Sep 9
Tomorrow
Sep 9 - Sep 10
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Our top choices for Key Largo luxury hotels

1. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
¥39,199
¥52,574 total
includes taxes & fees
Sep 23 - Sep 24
Playa Largo Resort & Spa, Autograph Collection

2. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
¥33,665
¥44,023 total
includes taxes & fees
Sep 16 - Sep 17
Reefhouse Resort & Marina

3. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
¥36,429
¥49,457 total
includes taxes & fees
Sep 28 - Sep 29
Baker's Cay Resort Key Largo, Curio Collection by Hilton

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
¥62,257
¥79,758 total
includes taxes & fees
Sep 16 - Sep 17
The Islands of Islamorada

5. Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
Homestead
¥70,138
¥103,681 total
includes taxes & fees
Sep 10 - Sep 11
Find Peace - Tiny House in Japanese Garden

6. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
¥30,091
¥44,228 total
includes taxes & fees
Sep 15 - Sep 16
Islander Resort

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
¥28,162
¥42,923 total
includes taxes & fees
Sep 16 - Sep 17
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

8. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
¥22,968
¥37,113 total
includes taxes & fees
Sep 15 - Sep 16
Cheeca Lodge & Spa

9. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
¥22,098
¥36,102 total
includes taxes & fees
Sep 28 - Sep 29
Amara Cay Resort
View all properties

Top Key Largo Hotel Reviews

The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"The staffs are really helpful! Environment is safe with security cameras and Waist band is given for hotel guest to walk in the area. Kayak‘s first 2 hr is free but needs to get it early. The location is great that is close to the greyhound bus station. The only problem bother me is the sound of AC is loud."
Yicheng 3-night trip
Posted 1 hour ago
The Pelican Key Largo Cottages
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Great experience"
Yvon 2-night trip
Posted 10 hours ago
Reefhouse Resort & Marina
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"Amazing"
Leilanis 1-night trip
Posted 14 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"Todo estaba limpio y cómodo..excelente para lugar"
Carlos 1-night trip
Posted 1 day ago
Waterside Suites & Marina
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

8/10 Good
"The room was clean and the staff was kind . Directions of the resort have been given by a map, not really clear without it . I would not suggest you to eat on the premises , the food is not that great , in the Italian restaurant the pizza was Frozen and the lobster pasta with parmesan cheese and not al dente , Italian ?No . Also in the other restaurants the food is décent but doesn’t justify the prices , you pay only for the view and to be in the resort . A family resort more than a solo traveler. Overall a four stars ."
Giulia 1-night trip
Posted 2 days ago
Playa Largo Resort & Spa, Autograph Collection
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"This property was clean and the staff was very friendly. It is a cozy little get away in Key Largo with nice restaurants close by. Would definitely stay again."
P 2-night trip
Posted 7 days ago
Amoray Dive Resort
Azul del Mar

Azul del Mar

10/10 Excellent
"A amazing location with private beach swimming pool next door and restaurants nearby Ideal chill out spot"
Stephen 2-night trip
Posted 10 days ago
Azul del Mar

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Bluefin Rock Harbor Marina, and John Pennekamp Coral Reef State Park. If you have a little extra time during your trip, you might want to make a stop at MarineLab Undersea Laboratory and Caribbean Club Bar.

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