A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
Oct 20 - Oct 21
Tomorrow
Oct 21 - Oct 22
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Key Largo luxury hotels

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A spacious living room with large windows, comfortable seating, and decorative plants.
A poolside area with blue chairs and a thatched-roof structure.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
￥34,714
￥45,394 total
includes taxes & fees
Oct 22 - Oct 23
Reefhouse Resort & Marina
An aerial view of a resort with a large pool, palm trees, and a beach.
A beachside patio with lounge chairs, a table, and a view of the ocean.
A beach with clear water, a wooden pier, and lounge chairs under a tree.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
￥47,959
￥62,679 total
includes taxes & fees
Nov 4 - Nov 5
Playa Largo Resort & Spa, Autograph Collection
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A tropical resort with a swimming pool, palm trees, and a waterfall.

3. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
￥29,608
￥44,884 total
includes taxes & fees
Nov 19 - Nov 20
Cheeca Lodge & Spa
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A pool area with clear blue water, white lounge chairs, and palm trees.
A gated entrance to a resort with palm trees and a clear sky.
A resort with multiple white buildings, each featuring balconies and surrounded by lush greenery and palm trees.

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
￥82,622
￥103,327 total
includes taxes & fees
Oct 28 - Oct 29
The Islands of Islamorada
View all properties

Top Key Largo Hotel Reviews

Reefhouse Resort & Marina

Reefhouse Resort & Marina

8/10 Good
"The hotel needs more amenities and activities."
Jorge 4-night trip
Posted 13 hours ago
Reefhouse Resort & Marina
Bayside Inn Key Largo

Bayside Inn Key Largo

8/10 Good
"I rented a suite (# 401), supposed to be the best. The problem is that I found a lot of deficiencies inside. First fan and light bulb in the room wasn’t working, no light bulb in the lamp corner of the room. Fan and light bulb not working either in dining table. The sofa was broken on the left side. My wife had to clean the stove and top of the refrigerator because too much dust and grease. I called maintenance and case was resolved more or less, but believe me for the price you paid for the suite I deserve better. Housekeeping should monitor better and check everything before rent any property. Outside the property was well maintained. Thanks to give me the the opportunity to explain a review of the place. However all staff on premises were very nice, helpful, courteous and friendly. Hope my review will be considered for future reference."
Raimundo 3-night trip
Posted 15 hours ago
Bayside Inn Key Largo
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"Friendly staff and the price is right"
Justin 1-night trip
Posted 22 hours ago
Amoray Dive Resort
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Every employee was very nice, tiki bartender was so friendly, the breakfast was amazing, big room with coffee and refrigerator were nice to have, pool, beach and kayaks were fun. easy parking and access right into the room, can’t wait to come back after the remodel. Sunset from the beach was a highlight."
Perry 1-night trip
Posted 1 day ago
Hampton Inn Key Largo Manatee Bay
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

8/10 Good
"The Pelican was nice. It was a little dated. They have a tiki bar but no bar. I think music would be great when you’re sitting out by the dock. We booked 2 days but left after 1. There is not a whole lot to do around the property. No town to go to for restaurants."
Tina 2-night trip
Posted 2 days ago
The Pelican Key Largo Cottages

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 4 restaurants and 3 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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