A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
Aug 28 - Aug 29
Tomorrow
Aug 29 - Aug 30
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Our top choices for Key Largo luxury hotels

1. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
¥37,765
¥51,272 total
includes taxes & fees
Sep 28 - Sep 29
Baker's Cay Resort Key Largo, Curio Collection by Hilton

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
¥39,340
¥53,038 total
includes taxes & fees
Sep 20 - Sep 21
Playa Largo Resort & Spa, Autograph Collection

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
¥34,880
¥45,612 total
includes taxes & fees
Sep 3 - Sep 4
Reefhouse Resort & Marina

4. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
¥23,731
¥38,344 total
includes taxes & fees
Sep 8 - Sep 9
Cheeca Lodge & Spa

5. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
¥57,337
¥74,430 total
includes taxes & fees
Aug 29 - Aug 30
The Islands of Islamorada

6. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
¥38,085
¥53,595 total
includes taxes & fees
Sep 22 - Sep 23
Islander Resort

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
¥27,920
¥43,065 total
includes taxes & fees
Sep 7 - Sep 8
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

8. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
¥21,438
¥35,772 total
includes taxes & fees
Aug 30 - Aug 31
Amara Cay Resort

9. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
¥21,394
¥35,715 total
includes taxes & fees
Sep 3 - Sep 4
La Siesta Resort & Villas

10. Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
Homestead
¥23,094
¥51,332 total
includes taxes & fees
Aug 30 - Aug 31
Find Peace - Tiny House in Japanese Garden
View all properties

Top Key Largo Hotel Reviews

The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

8/10 Good
"Poca iluminación en las habitaciones"
Gleiny 1-night trip
Posted 2 hours ago
The Pelican Key Largo Cottages
Azul del Mar

Azul del Mar

10/10 Excellent
"Quick communication. Great location. Large room. Well stocked kitchen. Put the sign on the door for cleaning and returned to fresh towels and empty trash. Quiet. Would stay again."
Nancy 2-night trip
Posted 3 hours ago
Azul del Mar
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Great place to stay, the bartender at the tiki hut was amazing."
Patrick 2-night trip
Posted 6 hours ago
Hampton Inn Key Largo Manatee Bay
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Excellent, but Hard beds"
Michael 3-night trip
Posted 13 hours ago
Bayside Inn Key Largo
Gilbert's Resort

Gilbert's Resort

10/10 Excellent
"Amazing staff and great place to stay for families."
Mel 6-night trip
Posted 17 hours ago
Gilbert's Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"This is our second visit to Baker's Cay, and it's a total go-to resort for our family. Highly recommend!"
Melissa 5-night trip
Posted 17 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"Me encantó la verdad. Fuimos un grupo familiar todos. Pero el echo de la cocina. El barbecue abajo. La piscina calentica. La verdad a nosotros nos encantó."
Rene 2-night trip
Posted 18 hours ago
Waterside Suites & Marina
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"The property was situated to make you feel like you were in a tropical paradise tucked away from the rest of the key. Very clean and nice. The staff was amazing and the private beach was one of the best."
Preston 2-night trip
Posted 2 days ago
Playa Largo Resort & Spa, Autograph Collection
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"The beach is private which adds a level of safety. The proximity of the pool to the beach front was very convenient. We had a great time at the Reefhouse and I will stay there again if I get back to Key Largo."
Gwen 6-night trip
Posted 3 days ago
Reefhouse Resort & Marina

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Bluefin Rock Harbor Marina, and John Pennekamp Coral Reef State Park. If you have a little extra time during your trip, you might want to make a stop at MarineLab Undersea Laboratory and Caribbean Club Bar.

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