A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
Aug 31 - Sep 1
Tomorrow
Sep 1 - Sep 2
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Our top choices for Key Largo luxury hotels

An aerial view of a resort with a large pool, palm trees, and a beach.
A beach with clear water, a wooden pier, and lounge chairs under a tree.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.

1. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
￥40,823
￥54,751 total
includes taxes & fees
Sep 14 - Sep 15
Playa Largo Resort & Spa, Autograph Collection
A hammock on a sandy beach with a view of the sea and a tree overhead.
A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.
A coconut drink with a straw, a cherry, and a slice of fruit on a table by a pool with a waterfall and palm trees in the background.
A spacious dining area with high ceilings, wicker furniture, and large windows.

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
￥37,938
￥51,506 total
includes taxes & fees
Sep 28 - Sep 29
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A spacious living room with large windows, comfortable seating, and decorative plants.

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
￥35,060
￥45,847 total
includes taxes & fees
Sep 1 - Sep 2
Reefhouse Resort & Marina
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A tropical resort with a swimming pool, palm trees, and a waterfall.
A spacious lobby with a seating area, a bar, and a large window providing a view of the outdoors.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.

4. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
￥23,853
￥38,542 total
includes taxes & fees
Sep 7 - Sep 8
Cheeca Lodge & Spa
A balcony with wicker chairs, a small table with drinks, and a view of the beach and ocean.
A resort with a pool, beach, and ocean view.
An outdoor dining area with round tables and chairs, a thatched roof, and a view of the sea.
A coastal resort with a beach, a swimming pool, and multiple buildings.

5. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
￥28,048
￥43,261 total
includes taxes & fees
Sep 7 - Sep 8
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.
An aerial view of a resort with a swimming pool, palm trees, and a dock.
A resort pool with palm trees, beach chairs, and umbrellas.
A beach with palm trees, a dock, and lounge chairs.

6. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
￥21,773
￥36,202 total
includes taxes & fees
Sep 2 - Sep 3
Amara Cay Resort
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
A wooden pier leading to a beach with palm trees and a row of beach huts.
A beachside patio with wooden furniture, a thatched roof, and a view of the ocean.
A paved pathway leading to a beach with palm trees and a view of the ocean.

7. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
￥37,109
￥52,553 total
includes taxes & fees
Sep 22 - Sep 23
Islander Resort
A row of beachside cottages with colorful exteriors, each with a beach chair and umbrella.
A row of colorful beach huts with palm trees in the background.
A beach with colorful buildings, kayaks, and lounge chairs.
A resort with a pool surrounded by palm trees and a view of the ocean.

8. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
￥21,504
￥35,899 total
includes taxes & fees
Sep 2 - Sep 3
La Siesta Resort & Villas
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A gated entrance to a resort with palm trees and a clear sky.
A pool area with clear blue water, white lounge chairs, and palm trees.
A resort with multiple white buildings, each featuring balconies and surrounded by lush greenery and palm trees.

9. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
￥57,632
￥74,814 total
includes taxes & fees
Sep 1 - Sep 2
The Islands of Islamorada
A wooden deck with a pergola, surrounded by lush greenery and a sandy area.
A wooden bridge over a pond with a gazebo and lush greenery.
A modern interior with a red sofa, wooden flooring, stone wall, and a kitchen area.
A two-story house with a wooden deck leading to the entrance, surrounded by large trees and potted plants.

10. Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
Homestead
￥72,841
￥107,676 total
includes taxes & fees
Sep 1 - Sep 2
Find Peace - Tiny House in Japanese Garden
View all properties

Top Key Largo Hotel Reviews

Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Excellent"
Ernestina 2-night trip
Posted 8 hours ago
Bayside Inn Key Largo
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

10/10 Excellent
"This was a perfect spot to stay, very convenient. Within walking distance to the dive shop we used."
Alyssa 4-night trip
Posted 10 hours ago
Holiday Inn Key Largo by IHG
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"A hidden gem in Key Largo ! The grounds and fun and the beach is heavenly. The rooms are clean and the staff is amazing ! I give Sunset Cove Beach Resort a (((10)))"
Anna 2-night trip
Posted 10 hours ago
Sunset Cove Beach Resort
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"Room was old"
Douglas 2-night trip
Posted 10 hours ago
The Pelican Key Largo Cottages
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

8/10 Good
"El aire acondicionado muy bueno frente a la marina esa vista me gustó"
Iraida moro 2-night trip
Posted 11 hours ago
Marina Del Mar Resort and Marina
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

8/10 Good
"I believe if they weren't in the midst of redecorating the rooms the scores would have been higher. They did a very good job of keeping the disruption to a minimum as well as keeping the grounds and parking as maintained as possible considering they had a lot of building supplies all around the property to accomplish the renovations. All-in all it was very good stay."
Jeff 2-night trip
Posted 12 hours ago
Hampton Inn Key Largo Manatee Bay
Azul del Mar

Azul del Mar

10/10 Excellent
"A amazing location with private beach swimming pool next door and restaurants nearby Ideal chill out spot"
Stephen 2-night trip
Posted 2 days ago
Azul del Mar

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Bluefin Rock Harbor Marina, and John Pennekamp Coral Reef State Park. If you have a little extra time during your trip, you might want to make a stop at MarineLab Undersea Laboratory and Caribbean Club Bar.

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