A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
Oct 26 - Oct 27
Tomorrow
Oct 27 - Oct 28
This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Key Largo luxury hotels

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
An aerial view of a resort with a large pool, sun loungers, and palm trees.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
￥34,355
￥44,925 total
includes taxes & fees
Oct 28 - Oct 29
Reefhouse Resort & Marina
An aerial view of a resort with a large pool, palm trees, and a beach.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.
A beachside patio with lounge chairs, a table, and a view of the ocean.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
￥47,532
￥62,121 total
includes taxes & fees
Nov 9 - Nov 10
Playa Largo Resort & Spa, Autograph Collection
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A spacious lobby with a seating area, a bar, and a large window providing a view of the outdoors.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A tropical resort with a swimming pool, palm trees, and a waterfall.

3. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
￥29,032
￥44,133 total
includes taxes & fees
Nov 1 - Nov 2
Cheeca Lodge & Spa
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A gated entrance to a resort with palm trees and a clear sky.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.
A pool area with clear blue water, white lounge chairs, and palm trees.

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
￥76,155
￥95,845 total
includes taxes & fees
Oct 28 - Oct 29
The Islands of Islamorada
View all properties

Top Key Largo Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"Amazing hotel with lots of on-site amenities and options for dinner. Loved the fishing in the morning."
Forrest 2-night trip
Posted 7 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"Absolutely loved our trip. The pelican reef was wonderful. The staff was excellent. It was clean comfortable and we really enjoyed the time we spent there."
kathy 7-night trip
Posted 13 hours ago
The Pelican Key Largo Cottages
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"I had a wonderful 7 day stay. The staff was outstanding. The breakfast buffet was good. The workers were prompt in maintaining the breakfast bar and quick to clean off a table. My room was clean and comfortable. The beach area could have used more sand because it had ruts in it from water flow, but there was ample seating. The pool area was nice. Lounge chairs, tables and chairs in good condition. Very nice outside tiki bar with plenty of seating as well. The sunsets from the beach area were amazing! If I ever travel back to Key Largo, I will stay here again."
Valerie 6-night trip
Posted 16 hours ago
Hampton Inn Key Largo Manatee Bay
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"Unique location and pet friendly"
JACQUELINE 2-night trip
Posted 22 hours ago
Sunset Cove Beach Resort
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Great location. Pool was extremely warm and a bit cloudy due to suntan lotion. Floor in the suite was also dirty as in your feet will be covered in minutes"
Richard 2-night trip
Posted 1 day ago
Bayside Inn Key Largo
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"😍"
Lisset 3-night trip
Posted 2 days ago
Waterside Suites & Marina
Azul del Mar

Azul del Mar

8/10 Good
"Property needs some maintenance"
DIANE 2-night trip
Posted 2 days ago
Azul del Mar
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"This place was awesome. Location, staff, property itself, all was excellent. Absolutely would come back and would highly recommend"
Rodrigo 1-night trip
Posted 2 days ago
Amoray Dive Resort

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 4 restaurants and 3 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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