Find Luxury Hotels in Key Largo, FL

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Check availability on Key Largo Luxury Hotels

Tonight
Dec 30 - Dec 31
Tomorrow
Dec 31 - Jan 1
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Key Largo luxury hotels

Outdoor pool, cabanas (surcharge), pool umbrellas
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1003)
"Beautiful location, great views, very clean property, room was great (great bed), friendly staff."
United States
Scott
The price is ￥65,975
￥82,821 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Playa Largo Resort & Spa, Autograph Collection
Marina
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

The Pelican Key Largo Cottages
2.0 star property
Key Largo
9.0 out of 10, Wonderful, (1005)
"Great place"
United States
Marc
The price is ￥22,876
￥25,735 total
includes taxes & fees
Jan 21 - Jan 22, 2026
The Pelican Key Largo Cottages
Terrace/patio
Bayside Inn Key Largo

Bayside Inn Key Largo

Bayside Inn Key Largo
3.0 star property
Key Largo
8.6 out of 10, Excellent, (1630)
"Great location, Relaxing friendly atmosphere. Very basic room amenities but beautiful beach, pool, experience "
United States
Rebecca
The price is ￥9,707
￥14,834 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Bayside Inn Key Largo
Gazebo
Sunset Cove Beach Resort

Sunset Cove Beach Resort

Sunset Cove Beach Resort
2.5 star property
Key Largo
9.0 out of 10, Wonderful, (1005)
"Always a great stay"
United States
Richard
The price is ￥32,442
￥36,497 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Sunset Cove Beach Resort
Exterior
Amoray Dive Resort

Amoray Dive Resort

Amoray Dive Resort
2.0 star property
Key Largo
9.2 out of 10, Wonderful, (1003)
"warm pool, great clean room"
United States
Heidi
The price is ￥19,385
￥26,195 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Amoray Dive Resort
Room, 1 King Bed, Bay View | Beach/ocean view
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay
2.5 star property
Key Largo
8.8 out of 10, Excellent, (1009)
"Great hotel"
United States
Elior
The price is ￥22,804
￥25,654 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hampton Inn Key Largo Manatee Bay
32-inch LCD TV with satellite channels, TV, iPod dock
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.6 out of 10, Excellent, (1002)
"One of the nicest hotels we have stayed at. Amazing staff, food, activities and property "
United States
Sara
The price is ￥53,588
￥68,885 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Baker's Cay Resort Key Largo, Curio Collection by Hilton
On the beach, kayaking
Azul del Mar

Azul del Mar

Azul del Mar
3.5 star property
Key Largo
9.0 out of 10, Wonderful, (805)
"one of the best hotel experiences I've had very quiet and right on the water "
United States
todd
Azul del Mar
Exterior
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina
2.5 star property
Key Largo
8.4 out of 10, Very Good, (1667)
"Excellent staff! Breakfast was outstanding!"
United States
David
The price is ￥19,814
￥26,678 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Marina Del Mar Resort and Marina
Outdoor pool, open 7:00 AM to 11:00 PM, pool umbrellas, sun loungers
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG
3.0 star property
Key Largo
8.6 out of 10, Excellent, (1018)
"Wonderful hotel. Great location Pool is amazing the staff was very friendly In all very good.. highly recommend "
United States
Christopher
The price is ￥29,478
￥33,163 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Key Largo by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Key Largo Hotel Reviews

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Everything was great! Friendly staff, clean rooms and definitely appreciated the little extras like welcome beverage, hot coca in the lobby and s’mores by the fire pit (recommend putting 2 marshmallows on the stick not just one 😉). Will be back in the near future!"
Angel 2-night trip
Posted 3 days ago
Playa Largo Resort & Spa, Autograph Collection

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
Known for its sunsets and boating, Key Largo also has some interesting things to see and do including Everglades National Park, so you may want to take in the local sights during your visit.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Everglades National Park, Jimmy Johnson's Big Chill, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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