A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
Aug 27 - Aug 28
Tomorrow
Aug 28 - Aug 29
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Our top choices for Key Largo luxury hotels

1. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
¥39,050
¥52,713 total
includes taxes & fees
Sep 27 - Sep 28
Baker's Cay Resort Key Largo, Curio Collection by Hilton

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
¥39,340
¥53,038 total
includes taxes & fees
Sep 20 - Sep 21
Playa Largo Resort & Spa, Autograph Collection

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
¥34,880
¥45,612 total
includes taxes & fees
Aug 30 - Aug 31
Reefhouse Resort & Marina

4. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
¥23,731
¥38,344 total
includes taxes & fees
Aug 28 - Aug 29
Cheeca Lodge & Spa

5. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
¥56,190
¥73,117 total
includes taxes & fees
Sep 1 - Sep 2
The Islands of Islamorada

6. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
¥38,085
¥53,595 total
includes taxes & fees
Sep 22 - Sep 23
Islander Resort

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
¥27,904
¥43,038 total
includes taxes & fees
Sep 7 - Sep 8
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

8. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
¥21,896
¥36,280 total
includes taxes & fees
Aug 30 - Aug 31
Amara Cay Resort

9. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
¥21,394
¥35,715 total
includes taxes & fees
Aug 30 - Aug 31
La Siesta Resort & Villas

10. Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
Homestead
¥23,094
¥51,332 total
includes taxes & fees
Aug 31 - Sep 1
Find Peace - Tiny House in Japanese Garden
View all properties

Top Key Largo Hotel Reviews

Gilbert's Resort

Gilbert's Resort

10/10 Excellent
"Amazing staff and great place to stay for families."
Mel 6-night trip
Posted 1 hour ago
Gilbert's Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"This is our second visit to Baker's Cay, and it's a total go-to resort for our family. Highly recommend!"
Melissa 5-night trip
Posted 1 hour ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"The property was situated to make you feel like you were in a tropical paradise tucked away from the rest of the key. Very clean and nice. The staff was amazing and the private beach was one of the best."
Preston 2-night trip
Posted 1 day ago
Playa Largo Resort & Spa, Autograph Collection
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

8/10 Good
"Extremely helpful staff, really nice people! Everything was nearby and convenient. You can swim, snorkel, and fish right here! Ice maker was very close too. My only issue was is that I wanted a kitchenette. There were two burners but no stove and the refrigerator didn't work. Staff was very helpful by bringing over a mini frig yet I still got charged for the kitchenette price. I would totally stay here again, but I would check out the unit before completing transaction."
Julie 3-night trip
Posted 2 days ago
The Pelican Key Largo Cottages
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"The beach is private which adds a level of safety. The proximity of the pool to the beach front was very convenient. We had a great time at the Reefhouse and I will stay there again if I get back to Key Largo."
Gwen 6-night trip
Posted 2 days ago
Reefhouse Resort & Marina
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

8/10 Good
"Intercom room door needs some maintenance. Bath tub very old,deteriorat."
Luis 3-night trip
Posted 2 days ago
Holiday Inn Key Largo by IHG
Azul del Mar

Azul del Mar

8/10 Good
"Nothing good to say about the drive and FL. However, the room: clean, comfy. No staff, really- just AI. It was good enough for our diving trip. The room was spacious but had thin walls (we heard the tenants next door all night). The groomed beach and dock wall out front were great."
Edward Patton 2-night trip
Posted 2 days ago
Azul del Mar
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

10/10 Excellent
"My go to spot in Key Largo. Great pool, great quiet location on the canal. Restaurants and bar right there. And free breakfast. 5stars!"
sandra 1-night trip
Posted 2 days ago
Marina Del Mar Resort and Marina

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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