A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Find Luxury Hotels in Key Largo, FL

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Check availability on Key Largo Luxury Hotels

Tonight
Aug 21 - Aug 22
Tomorrow
Aug 22 - Aug 23
This weekend
Aug 21 - Aug 23
Next weekend
Aug 28 - Aug 30

Our top choices for Key Largo luxury hotels

1. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
¥40,277
¥54,075 total
includes taxes & fees
Sep 21 - Sep 22
Baker's Cay Resort Key Largo, Curio Collection by Hilton

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
¥37,817
¥51,267 total
includes taxes & fees
Sep 3 - Sep 4
Playa Largo Resort & Spa, Autograph Collection

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
¥34,652
¥45,313 total
includes taxes & fees
Aug 27 - Aug 28
Reefhouse Resort & Marina

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
¥55,824
¥72,640 total
includes taxes & fees
Aug 27 - Aug 28
The Islands of Islamorada

5. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
¥34,381
¥49,359 total
includes taxes & fees
Sep 2 - Sep 3
Islander Resort

6. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
¥32,786
¥48,456 total
includes taxes & fees
Aug 27 - Aug 28
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

7. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
¥23,576
¥38,094 total
includes taxes & fees
Sep 2 - Sep 3
Cheeca Lodge & Spa

8. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
¥24,732
¥39,395 total
includes taxes & fees
Aug 30 - Aug 31
Amara Cay Resort

9. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
¥24,458
¥39,086 total
includes taxes & fees
Aug 26 - Aug 27
La Siesta Resort & Villas
View all properties

Top Key Largo Hotel Reviews

Amoray Dive Resort

Amoray Dive Resort

8/10 Good
"Really nice dive hotel."
Paul 1-night trip
Posted 10 hours ago
Amoray Dive Resort
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Superb location. Great Tiki bar!"
John 1-night trip
Posted 2 days ago
Hampton Inn Key Largo Manatee Bay
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"The room we stayed was completely renovated very clean and bug free The grounds were well maintained The staff is very friendly and helpful We will be staying here again asap"
Walter 2-night trip
Posted 2 days ago
Sunset Cove Beach Resort
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"Great one night stay. Property was clean and convenient!"
Jennifer 1-night trip
Posted 2 days ago
Waterside Suites & Marina
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

8/10 Good
"Todo excelente y económico"
Yoel 1-night trip
Posted 3 days ago
Marina Del Mar Resort and Marina
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"Recommend!"
Fares 2-night trip
Posted 3 days ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Reefhouse Resort & Marina is a luxury hotel with a private beach and 3 restaurants, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Playa Largo Resort & Spa, Autograph Collection.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and John Pennekamp Coral Reef State Park. If you have a little extra time during your trip, you might want to make a stop at MarineLab Undersea Laboratory and Caribbean Club Bar.

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