A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
Oct 16 - Oct 17
Tomorrow
Oct 17 - Oct 18
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for Key Largo luxury hotels

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.
A poolside area with blue chairs and a thatched-roof structure.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
￥34,620
￥45,271 total
includes taxes & fees
Oct 18 - Oct 19
Reefhouse Resort & Marina
An aerial view of a resort with a large pool, palm trees, and a beach.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.
A beach with clear water, a wooden pier, and lounge chairs under a tree.

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
￥44,104
￥58,333 total
includes taxes & fees
Nov 1 - Nov 2
Playa Largo Resort & Spa, Autograph Collection
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.
A tropical resort with a swimming pool, palm trees, and a waterfall.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.

3. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
￥29,256
￥44,472 total
includes taxes & fees
Oct 19 - Oct 20
Cheeca Lodge & Spa
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A resort with multiple white buildings, each featuring balconies and surrounded by lush greenery and palm trees.
A gated entrance to a resort with palm trees and a clear sky.
A pool area with clear blue water, white lounge chairs, and palm trees.

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
￥76,741
￥96,584 total
includes taxes & fees
Oct 29 - Oct 30
The Islands of Islamorada
View all properties

Top Key Largo Hotel Reviews

Bayside Inn Key Largo

Bayside Inn Key Largo

8/10 Good
"The lady at the desk TJ was kind and helpful. Very nice room and area"
Anna 1-night trip
Posted 5 hours ago
Bayside Inn Key Largo
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Place was under a little construction, but didn’t effect our stay . Only had a one night stay . Room clean , breakfast had many choices . Staff was very outstanding . Very professional and courteous"
melinda 1-night trip
Posted 6 hours ago
Hampton Inn Key Largo Manatee Bay
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"The room was clean and the property was beautiful."
Darryl 2-night trip
Posted 9 hours ago
Reefhouse Resort & Marina
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"Cute little place. Beautiful and convenient location near the state park and walkable to restaurants."
Kirsten 2-night trip
Posted 1 day ago
Amoray Dive Resort
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"Esther was really helpful. Very nice and professional. Room was spotless!! Balcony with a beautiful view."
Manuel 1-night trip
Posted 2 days ago
Waterside Suites & Marina
Gilbert's Resort

Gilbert's Resort

10/10 Excellent
"La habitación fue un éxito muy linda y limpia grande y no hay de que quejarse, la piscina súper limpia, la atención de los meseros muy amable y atención buena"
Reimundo 1-night trip
Posted 3 days ago
Gilbert's Resort
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Everything was amazing!!! Beautiful hotel and great location."
Jorge 4-night trip
Posted 4 days ago
Playa Largo Resort & Spa, Autograph Collection
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"Everything was wonderful, clean room, nice and cool. Beach area had floats and paddle boards for guest use. Enjoyed a short walk to a great restaurant."
Tracy 1-night trip
Posted 4 days ago
Sunset Cove Beach Resort

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 4 restaurants and 3 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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