A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Find Luxury Hotels in Key Largo, FL

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Check availability on Key Largo Luxury Hotels

Tonight
Oct 18 - Oct 19
Tomorrow
Oct 19 - Oct 20
Next weekend
Oct 23 - Oct 25
In two weeks
Oct 30 - Nov 1

Our top choices for Key Largo luxury hotels

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
¥31,446
¥41,699 total
includes taxes & fees
Oct 19 - Oct 20
Reefhouse Resort & Marina

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
¥47,880
¥62,577 total
includes taxes & fees
Nov 2 - Nov 3
Playa Largo Resort & Spa, Autograph Collection

3. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
¥27,672
¥42,686 total
includes taxes & fees
Oct 20 - Oct 21
Cheeca Lodge & Spa

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
¥75,888
¥95,603 total
includes taxes & fees
Oct 20 - Oct 21
The Islands of Islamorada
View all properties

Top Key Largo Hotel Reviews

Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"The room was very clean and comfortable. Best shower ever! Nice shampoo, conditioner, and body lotion. Great fluffy towels, and ice cold air conditioning… What more could you want? Great location next to snooks restaurant/bar. Refreshing little pool next to a beach if you wanna sit in the sand. Cute chickens, roosters, and iguanas roaming around. Walking distance to Burger King, Starbucks, sandal, factory, Walgreens… Just a great hotel and a great location!"
Susan 7-night trip
Posted 10 hours ago
Bayside Inn Key Largo
Gilbert's Resort

Gilbert's Resort

10/10 Excellent
"Good stay. Breakfast was good and the staff are very friendly."
Ran 2-night trip
Posted 17 hours ago
Gilbert's Resort
Reefhouse Resort & Marina

Reefhouse Resort & Marina

8/10 Good
"Room are a little dated but overall nice. Pool and beach area were well maintained. We got couples massages and those were great. Pricing for them was reasonable. We would come back again!"
Austin 3-night trip
Posted 18 hours ago
Reefhouse Resort & Marina
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"Cute little place. Beautiful and convenient location near the state park and walkable to restaurants."
Kirsten 2-night trip
Posted 4 days ago
Amoray Dive Resort
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"Esther was really helpful. Very nice and professional. Room was spotless!! Balcony with a beautiful view."
Manuel 1-night trip
Posted 4 days ago
Waterside Suites & Marina
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"Everything was wonderful, clean room, nice and cool. Beach area had floats and paddle boards for guest use. Enjoyed a short walk to a great restaurant."
Tracy 1-night trip
Posted 6 days ago
Sunset Cove Beach Resort

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 4 restaurants and 3 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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