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Discover 1,757 Southhampton hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Red Lion Inn & Suites Pontoon Beach
Relax in a spacious room with a large bed, bedside table, and desk area.

Red Lion Inn & Suites Pontoon Beach

2.5 star property
8.0 out of 10, Very Good, (453)
"Had a great stay here. Room was nice and staff were very friendly. Lots of places to eat within a 15 minute drive and breakfast was very good."
The price is ￥10,137
￥11,474 total
includes taxes & fees
Jul 29 - Jul 30
Red Lion Inn & Suites Pontoon Beach
Pear Tree Inn St. Louis Airport
Relax in a spacious indoor area with comfortable seating options and a reception desk.

Pear Tree Inn St. Louis Airport

2.5 star property
9.4 out of 10, Exceptional, (2648)
"Great location, clean and great breakfast!"
The price is ￥13,179
￥15,515 total
includes taxes & fees
Jul 30 - Jul 31
Pear Tree Inn St. Louis Airport
Best Western Plus St. Louis Airport Hotel
Experience the modern design of this hotel, featuring a prominent entrance with a canopy and stone pillars, surrounded by landscaped gardens and a parking lot.

Best Western Plus St. Louis Airport Hotel

2.5 star property
9.2 out of 10, Wonderful, (1011)
"Easy check in and the rooms were excellent, great value."
The price is ￥16,058
￥19,861 total
includes taxes & fees
Jul 29 - Jul 30
Best Western Plus St. Louis Airport Hotel
The Wildwood Hotel
Enjoy a romantic dinner for two with fine china, linens, and elegant table settings.

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1559)
"Great location for our stay"
The Wildwood Hotel
Wingate by Wyndham St. Louis Airport
Two spacious beds with dark headboards and white linens, accompanied by bedside tables and lamps.

Wingate by Wyndham St. Louis Airport

2.5 star property
9.4 out of 10, Exceptional, (1350)
"Very convenient to the airport and car rental return."
The price is ￥16,754
￥19,725 total
includes taxes & fees
Jul 30 - Jul 31
Wingate by Wyndham St. Louis Airport
The Principal Hotel
The Principal Hotel features a modern facade with a flat roof and large windows, set amidst a landscaped area with parking and shrubs.

The Principal Hotel

3.5 star property
9.8 out of 10, Exceptional, (100)
"Perfect stay! "
The price is ￥15,200
￥16,869 total
includes taxes & fees
Jul 27 - Jul 28
The Principal Hotel
Super 8 by Wyndham Belleville St. Louis Area
Relax in a stylish room with a large bed, blue accent wall, and a framed view of the Gateway Arch.

Super 8 by Wyndham Belleville St. Louis Area

2.0 star property
7.4 out of 10, Good, (811)
"Nice property close to everything in the Belleville area. They have a very nice staff and I enjoyed staying here very much., "
The price is ￥9,336
￥10,641 total
includes taxes & fees
Jul 27 - Jul 28
Super 8 by Wyndham Belleville St. Louis Area
Drury Inn & Suites St. Louis Collinsville
Relax in our spacious lobby with comfortable seating and a view of the outdoors.

Drury Inn & Suites St. Louis Collinsville

3.0 star property
9.6 out of 10, Exceptional, (1005)
"Great place to stay "
The price is ￥16,254
￥18,689 total
includes taxes & fees
Jul 29 - Jul 30
Drury Inn & Suites St. Louis Collinsville
Hyatt Regency St. Louis at The Arch
Relax in the elegant lobby, featuring a comfortable seating area with a sofa and armchairs, a staircase, and a chandelier.

Hyatt Regency St. Louis at The Arch

4.0 star property
8.4 out of 10, Very Good, (3884)
"Wonderful stay! "
The price is ￥15,700
￥18,514 total
includes taxes & fees
Aug 22 - Aug 23
Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch
Relax in style with a cityscape view from this outdoor seating area, featuring wicker chairs and ottomans on a tiled floor.

Drury Plaza Hotel St. Louis at the Arch

3.0 star property
9.4 out of 10, Exceptional, (2879)
"Great place to stay"
The price is ￥20,502
￥23,973 total
includes taxes & fees
Jul 31 - Aug 1
Drury Plaza Hotel St. Louis at the Arch
Super 8 by Wyndham Waterloo
Welcome to our reception area, featuring a comfortable desk, reception counter, and a beautiful potted plant.

Super 8 by Wyndham Waterloo

2.0 star property
7.6 out of 10, Good, (348)
"Very clean and comfortable. "
The price is ￥11,203
￥12,434 total
includes taxes & fees
Jul 30 - Jul 31
Super 8 by Wyndham Waterloo
Drury Inn & Suites St. Louis Airport
Enjoy meals with friends and family in this spacious dining area, featuring wooden tables and comfortable seating.

Drury Inn & Suites St. Louis Airport

3.0 star property
9.2 out of 10, Wonderful, (1016)
"Wonderful place to stay very close to the airport! "
The price is ￥16,254
￥19,072 total
includes taxes & fees
Jul 29 - Jul 30
Drury Inn & Suites St. Louis Airport
Drury Inn & Suites St. Louis Fairview Heights
Two beds with classic headboards and bedside tables, a wall-mounted TV, desk, and chair, and a window with curtains.

Drury Inn & Suites St. Louis Fairview Heights

3.0 star property
9.2 out of 10, Wonderful, (1008)
"Nice staff, great breakfast, clean rooms"
The price is ￥13,692
￥15,468 total
includes taxes & fees
Jul 29 - Jul 30
Drury Inn & Suites St. Louis Fairview Heights
Wingate by Wyndham St. Louis/Fenton Route 66
Two single beds with white linens and a patterned bed runner, each with a bedside table and lamp.

Wingate by Wyndham St. Louis/Fenton Route 66

3.0 star property
8.2 out of 10, Very Good, (1025)
"Decent hotel for its price!"
The price is ￥13,070
￥15,095 total
includes taxes & fees
Jul 27 - Jul 28
Wingate by Wyndham St. Louis/Fenton Route 66
Days Inn by Wyndham Collinsville/St. Louis
Relax in comfort with a large bed, bedside tables, and a cityscape artwork above.

Days Inn by Wyndham Collinsville/St. Louis

2.5 star property
7.2 out of 10, Good, (1014)
"Great stay"
The price is ￥8,963
￥10,306 total
includes taxes & fees
Aug 10 - Aug 11
Days Inn by Wyndham Collinsville/St. Louis
Pear Tree Inn St. Louis Arnold
Relax in a spacious room with expansive views of the surrounding landscape, featuring a round table and comfortable seating options.

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1008)
"Nice overnight stay"
The price is ￥13,179
￥15,234 total
includes taxes & fees
Jul 29 - Jul 30
Pear Tree Inn St. Louis Arnold
21C Museum Hotel St Louis
Classic architecture with a grand entrance and evenly spaced windows.

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1267)
"Great place to stay. "
The price is ￥23,527
￥28,243 total
includes taxes & fees
Jul 28 - Jul 29
21C Museum Hotel St Louis
The Knight Center at Washington University
Relax in the elegantly furnished lobby with a central bar, comfortable seating, and classic paneling.

The Knight Center at Washington University

2.5 star property
9.4 out of 10, Exceptional, (355)
"Very nice place to stay and stuff was great "
The price is ￥22,282
￥25,622 total
includes taxes & fees
Aug 7 - Aug 8
The Knight Center at Washington University
Moonrise Hotel
Experience the modern hotel's inviting entrance, complete with a covered walkway and outdoor seating area.

Moonrise Hotel

4.0 star property
9.0 out of 10, Wonderful, (1820)
"Moonrise is always a great stay. Fun hotel that is clean with friendly staff. "
The price is ￥20,957
￥24,924 total
includes taxes & fees
Aug 3 - Aug 4
Moonrise Hotel
St. Louis Airport Hotel
Conveniently located near St. Louis Airport, this hotel offers a range of rooms with balconies and windows, along with a bar, restaurant, and café.

St. Louis Airport Hotel

3.5 star property
7.4 out of 10, Good, (840)
"Good Stay will be back "
The price is ￥11,991
￥14,164 total
includes taxes & fees
Jul 28 - Jul 29
St. Louis Airport Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Southhampton

Find the best Southhampton areas and neighborhoods for the activities you enjoy most.
Meeting of the Waters Fountain showing a statue or sculpture and a fountain
Downtown St. Louis map

Downtown St. Louis

3 out of top 10 points of interest in this area

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Clayton map

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End
Central West End map

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Creve Coeur map

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

St. Louis which includes interior views
Downtown West map

Downtown West

3 out of top 10 points of interest in this area

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Top Southhampton Hotel Reviews

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark

10/10 Excellent
"Staff was wonderful. Room was clean. Valet was great. Bar had good food and drinks. "
Kelsey 1-night trip
Posted 1 day ago
Hilton St. Louis at the Ballpark

Frequently asked questions

What is Southhampton like?

Travelers to the Southhampton neighborhood in St. Louis will be sure to enjoy their stay.

What's a favorite place to stay in Southhampton?

For your stay in Southhampton, ☆Spacious and Comfy☆Central Location☆Near Downtown is one of the top choices based on our traveler data. Another good option for your stay in the neighborhood is Cozy home in the South Hampton / Tower Grove Area.

How many hotels will I find in the Southhampton area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 21 Southhampton hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Southhampton, will I receive a refund?

Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to view the best deals in Southhampton.

Where can I learn more about changing or cancelling my trip to Southhampton?

To find more details about rescheduling or cancelling your trip to Southhampton, click here.

What can I see and do in this St. Louis neighborhood?

A few places to visit in the area around Southhampton include Miniature Museum of Greater St. Louis, Lindenwood Park, and River des Peres Greenway Trailhead. When you're sightseeing in St. Louis, Tower Grove Tennis Center and George Washington Carver Garden are also worth a stop.