A historic church with intricate architecture and a large open plaza with people.

Find 5 Star Hotels in Santa Maria Novella from ￥14,244

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Our top choices for Santa Maria Novella 5-star hotels

A spacious room with a large window, a chandelier, and a sofa.

1. The St. Regis Florence

The St. Regis Florence
5.0 star property
Historic Centre of Florence
9.6 out of 10, Exceptional, (281 reviews)
"The room was very big and well decorated, the staff was very helpful"
United States
Anna
The price is ￥137,826
￥154,446 total
includes taxes & fees
Nov 12 - Nov 13
The St. Regis Florence
An outdoor seating area with tables and chairs, a large decorative letter, and historic buildings in the background.

2. W Florence

W Florence
5.0 star property
Historic Centre of Florence
9.4 out of 10, Exceptional, (22 reviews)
"Location is great right a few steps to all sites of interest Nice comfortable beds No noise rooms Amazingly helpful and friendly staff 3 min walk from the train station"
United States
lilia
The price is ￥83,823
￥95,042 total
includes taxes & fees
Nov 7 - Nov 8
W Florence
A hotel entrance with a classic arched doorway, green shutters, and a decorative awning.

3. Anglo American Hotel Florence, Curio Collection by Hilton

Anglo American Hotel Florence, Curio Collection by Hilton
5.0 star property
Historic Centre of Florence
8.4 out of 10, Very good, (820 reviews)
"Great location, service and food."
United States
Marina
The price is ￥34,255
￥40,517 total
includes taxes & fees
Nov 3 - Nov 4
Anglo American Hotel Florence, Curio Collection by Hilton
A building with a white facade, multiple arched windows, and a well-maintained garden with outdoor seating.

4. Dimora Palanca Boutique & SPA

Dimora Palanca Boutique & SPA
5.0 star property
Historic Centre of Florence
9.2 out of 10, Wonderful, (77 reviews)
"The accommodation very much complimented our wonderful experience and love for Florence. Our room, the connected amenities and the wonderful attentive service made our trip very memorable."
Australia
Brett
The price is ￥34,018
￥40,256 total
includes taxes & fees
Nov 9 - Nov 10
Dimora Palanca Boutique & SPA
A rooftop terrace with a hot tub, lounge chairs, and ambient lighting.

5. Sina Villa Medici, Autograph Collection

Sina Villa Medici, Autograph Collection
5.0 star property
Historic Centre of Florence
8.6 out of 10, Excellent, (331 reviews)
"Beautiful property and very attentive staff."
Canada
Ruth
The price is ￥67,228
￥76,788 total
includes taxes & fees
Nov 9 - Nov 10
Sina Villa Medici, Autograph Collection
A terrace with chairs and a table, overlooking a river and a cityscape with historic buildings.

6. The Excelsior, a Luxury Collection Hotel, Florence

The Excelsior, a Luxury Collection Hotel, Florence
5.0 star property
Historic Centre of Florence
9.4 out of 10, Exceptional, (373 reviews)
"Stunning hotel"
United Kingdom
Ruth
The price is ￥95,915
￥108,343 total
includes taxes & fees
Nov 12 - Nov 13
The Excelsior, a Luxury Collection Hotel, Florence
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Maria Novella.
The Social Hub Florence Belfiore

The Social Hub Florence Belfiore

Viale Belfiore, 55 Florence FI
The price is ￥10,693 per night from Nov 8 to Nov 9
￥10,693
￥14,244 total
Nov 8 - Nov 9
includes taxes & fees
9.4/10 Exceptional! (781 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santa Maria Novella Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Santa Maria Novella?
According to reviews by Expedia customers, Palazzo Montebello is one of the top-rated retreats for a luxurious stay in the Porta al Prato neighborhood of Santa Maria Novella. Want more 5-star hotels around the area? Sina Villa Medici, Autograph Collection and The St. Regis Florence will cater to your upscale desires.
How much does it cost to stay in a 5-star hotel in Santa Maria Novella?
The amount you pay for a 5-star hotel in Santa Maria Novella can vary based on the time of year you travel and how long you plan to be away, among several factors. Use our price per night filter and other search tools to score the best deal on a high-end stay.

  • Search for the lowest price per night from ￥14,244

What makes a hotel 5 stars in Santa Maria Novella?
In Santa Maria Novella, a hotel needs to provide a certain number of high-end conveniences to earn a 5-star rating. These can include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, luxury bathroom products and more. What also sets 5-star hotels apart is their guest-focused standard of service. You can expect things like nightly turn-down services, concierge services and in-room massages. Some may even offer thoughtful touches such as a welcome gift.