A historic church with intricate architecture and a large open plaza with people.

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Our top choices for Santa Maria Novella 5-star hotels

A spacious room with a large window, a chandelier, and a sofa.

1. The St. Regis Florence

The St. Regis Florence
5.0 star property
Historic Centre of Florence
9.6 out of 10, Exceptional, (283 reviews)
"The building is absolutely incredible. Beautiful architecture and design. Alexander was a fabulous waiter at the restaurant. The food, the staff and everything was perfect."
United States
Scott
The price is ￥138,038
￥154,682 total
includes taxes & fees
Nov 12 - Nov 13
The St. Regis Florence
An outdoor seating area with tables and chairs, a large decorative letter, and historic buildings in the background.

2. W Florence

W Florence
5.0 star property
Historic Centre of Florence
9.0 out of 10, Wonderful, (25 reviews)
"Very clean comfortable room with great air conditioning. The bed was amazing and allowed us to sleep soundly in the dark room after traveling. The rooftop bar was a plus and and even hotel inside bar was great. Would definitely recommend this newer hotel. Staff were friendly and was in a walkable location to everything."
United States
Heather
The price is ￥83,952
￥95,188 total
includes taxes & fees
Nov 15 - Nov 16
W Florence
A neatly arranged hotel room with a large bed, a bedside table, a small table with books, a red chair, and a painting on the wall.

3. Anglo American Hotel Florence, Curio Collection by Hilton

Anglo American Hotel Florence, Curio Collection by Hilton
5.0 star property
Historic Centre of Florence
8.4 out of 10, Very good, (820 reviews)
"Great location, service and food."
United States
Marina
The price is ￥34,307
￥40,579 total
includes taxes & fees
Nov 8 - Nov 9
Anglo American Hotel Florence, Curio Collection by Hilton
A building with a white facade, multiple arched windows, and a well-maintained garden with outdoor seating.

4. Dimora Palanca Boutique & SPA

Dimora Palanca Boutique & SPA
5.0 star property
Historic Centre of Florence
9.2 out of 10, Wonderful, (78 reviews)
"The accommodation very much complimented our wonderful experience and love for Florence. Our room, the connected amenities and the wonderful attentive service made our trip very memorable."
Australia
Brett
The price is ￥32,008
￥38,050 total
includes taxes & fees
Nov 9 - Nov 10
Dimora Palanca Boutique & SPA
A rooftop terrace with a hot tub, lounge chairs, and ambient lighting.

5. Sina Villa Medici, Autograph Collection

Sina Villa Medici, Autograph Collection
5.0 star property
Historic Centre of Florence
8.6 out of 10, Excellent, (332 reviews)
"Beautiful property and very attentive staff."
Canada
Ruth
The price is ￥67,331
￥76,905 total
includes taxes & fees
Nov 9 - Nov 10
Sina Villa Medici, Autograph Collection
A terrace with chairs and a table, overlooking a river and a cityscape with historic buildings.

6. The Excelsior, a Luxury Collection Hotel, Florence

The Excelsior, a Luxury Collection Hotel, Florence
5.0 star property
Historic Centre of Florence
9.4 out of 10, Exceptional, (374 reviews)
"Stunning hotel"
United Kingdom
Ruth
The price is ￥96,062
￥108,510 total
includes taxes & fees
Nov 12 - Nov 13
The Excelsior, a Luxury Collection Hotel, Florence
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Top Santa Maria Novella Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Santa Maria Novella?
According to reviews by Expedia customers, Palazzo Montebello is one of the top-rated retreats for a luxurious stay in the Porta al Prato neighborhood of Santa Maria Novella. Want more 5-star hotels around the area? Sina Villa Medici, Autograph Collection and The St. Regis Florence will cater to your upscale desires.
How much does it cost to stay in a 5-star hotel in Santa Maria Novella?
The amount you pay for a 5-star hotel in Santa Maria Novella can vary based on the time of year you travel and how long you plan to be away, among several factors. Use our price per night filter and other search tools to score the best deal on a high-end stay.

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What makes a hotel 5 stars in Santa Maria Novella?
In Santa Maria Novella, a hotel needs to provide a certain number of high-end conveniences to earn a 5-star rating. These can include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, luxury bathroom products and more. What also sets 5-star hotels apart is their guest-focused standard of service. You can expect things like nightly turn-down services, concierge services and in-room massages. Some may even offer thoughtful touches such as a welcome gift.