Find hotels in Uptown - Upper Duval, Key West from ¥14,578
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Discover 2,793 Uptown - Upper Duval hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Southwinds Motel
Southwinds Motel

Orchid Key Inn - Adults Only
Orchid Key Inn - Adults Only

The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only

Santa Maria Suites
Santa Maria Suites

Douglas House
Douglas House

Kona Kai Oasis
Kona Kai Oasis
Where to stay in Uptown - Upper Duval

Old Town Key West
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.

Key West Historic District
Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.

Beachside
If you're spending some time in Beachside, Smathers Beach and Florida Keys Beaches are top sights worth seeing.

Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

New Town
Though New Town might not have many top sights, you can venture to the surrounding area to see attractions like Smathers Beach and Key West Tropical Forest and Botanical Garden.
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in top Key West neighborhoods
- Hotels in Old Town Key West
- Hotels in Key West Historic District
- Hotels in New Town
- Hotels in Historic Seaport
- Hotels in Truman Annex
- Hotels in Uptown - Upper Duval
- Hotels in Bahama Village
- Hotels in Casa Marina
- Hotels in Midtown
- Hotels in Sunset Key
- Hotels in Meadows
- Hotels in Geiger Key
- Hotels in White Street Gallery District
Hotels near popular Key West Attractions
More Accommodation Types in Uptown - Upper Duval
- Vacation Homes in Key West
- Condo Rentals in Key West
- Apartments in Key West
- Cottages in Key West
- Houseboats in Key West
- Resorts in Key West
- Guest Houses in Key West
- Villas in Key West
- B&B in Key West
- Aparthotels in Key West
- Cabin Rentals in Key West
- Hostels in Key West
- Inns in Key West
- Motels in Key West
Hotels Close to Nearby Airports
Explore more hotels
- Pelican Suite | Cozy Cottage, Hot Tubs, Close to Duval!
- Southernmost Retreat | On Duval! With Hot Tub, Patio, & Private Parking
- Heron Suite | Vibrant Retreat, Hot Tubs, Steps from Duval Street!
- Beachside Resort & Residences
- Hyatt Centric Key West Resort and Spa
- Margaritaville Beach House Key West
- Casa Marina Key West, Curio Collection by Hilton
- Oceans Edge Key West Resort, Hotel & Marina
- Hyatt Vacation Club at Windward Pointe, Key West
- Fairfield Inn and Suites by Marriott Key West
- DoubleTree Resort by Hilton Grand Key - Key West
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