
Uptown - Upper Duval Vacations
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Where to stay in Uptown - Upper Duval
Find the best Uptown - Upper Duval areas and neighborhoods for the activities you enjoy most. Learn more about Uptown - Upper Duval

Old Town Key West
4 out of top 10 points of interest in this area
4.5/5(226 area reviews)
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Uptown - Upper Duval Hotel Deals

Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
Fully refundableReserve now, pay when you stay
The price is ¥27,348 per night from Nov 30 to Dec 1
¥27,348
¥42,204 total
Nov 30 - Dec 1
includes taxes & fees
8.6/10 Excellent! (2,881 reviews)
A1
Reviewed on Nov 24, 2025

The Reach Key West, Curio Collection by Hilton
1435 Simonton Street Key West FL
Fully refundableReserve now, pay when you stay
The price is ¥35,783 per night from Dec 17 to Dec 18
¥35,783
¥49,641 total
Dec 17 - Dec 18
includes taxes & fees
8.4/10 Very Good! (1,005 reviews)
Spacious room, staff courteous
Reviewed on Nov 20, 2025

The Southernmost Inn - Adults Only
525 United Street Key West FL
Fully refundableReserve now, pay when you stay
The price is ¥20,177 per night from Dec 7 to Dec 8
¥20,177
¥29,736 total
Dec 7 - Dec 8
includes taxes & fees
8.2/10 Very Good! (1,195 reviews)
Exceeded expectations
Reviewed on Nov 22, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Uptown - Upper Duval

Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.

South Beach
The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

Key West Butterfly and Nature Conservatory
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do

Miami to Key West Day Trip with Activity Options
¥5,954
per adult
84% of travellers recommend

Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
¥7,625
per adult
92% of travellers recommend

Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar
¥4,189
per adult
80% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.



