Uptown - Upper Duval, FL
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.
Key West Butterfly and Nature Conservatory
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
Key West Afternoon At The Reef Snorkeling Adventure with Open Bar!
Miami to Key West Day Trip with Activity Options
Key West Sunset Sail with Live Music, Drinks and Appetizers!
Key West Sunset Cruise & Glass Bottom Eco Tour
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
Clean room, great staff, amenities and location.
Reviewed on Feb 23, 2026
The Reach Key West, Curio Collection by Hilton
Clean room great staff
Reviewed on Feb 24, 2026
The Southernmost Inn - Adults Only
The hotel was straight trash, room and hotel was dirty, bathroom had mold, and the shower was disgusting cannot believe that this place was accepting guests or that people would book at this location the worst experience in my life
Reviewed on Feb 24, 2026
Southwinds Motel
Love this place the people Everytgong
Reviewed on Feb 23, 2026
Douglas House
Friendly and knowledgeable staff. The room was clean and spaciousness. Location was perfect. If i return to key west i will stay here!
Reviewed on Feb 23, 2026
Orchid Key Inn - Adults Only
Loved this little hotel. It’s right in the heart of Duval Street, with so much going on, yet we never heard a peep in our room. It was surprisingly quiet and peaceful. We originally booked just one night but ended up adding another. We did have to switch rooms, but the staff had our second room ready ...
Reviewed on Feb 22, 2026
Check Uptown - Upper Duval hotel availability
Other neighborhoods around Uptown - Upper Duval
Old Town Key West
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Bahama Village
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Key West Historic District
Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area.
