Uptown - Upper Duval, FL
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.
Key West Butterfly and Nature Conservatory
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Miami to Key West Day Trip with Activity Options
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar
Key West Sunset Cruise & Glass Bottom Eco Tour
Key West Sunset Sail with Live Music, Drinks and Appetizers!
Historic Key West Old Town Trolley Hop-On Hop-Off Tour
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
Clean
Reviewed on Nov 18, 2025
The Reach Key West, Curio Collection by Hilton
Spacious room, staff courteous
Reviewed on Nov 20, 2025
The Southernmost Inn - Adults Only
Exceeded expectations
Reviewed on Nov 22, 2025
Southwinds Motel
Clean room, friendly staff, location
Reviewed on Nov 21, 2025
Southernmost House
Hospitality and location
Reviewed on Nov 20, 2025
Santa Maria Suites
Spotless place. Great front desk concierge service. Nice people stayed there when we were there. Loved the accommodations.
Reviewed on Nov 19, 2025
Check Uptown - Upper Duval hotel availability
Other neighborhoods around Uptown - Upper Duval
Old Town Key West
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Bahama Village
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.
Key West Historic District
Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area.
Uptown - Upper Duval, FL
- Southernmost Point
- South Beach
- Key West Butterfly and Nature Conservatory
- Duval Street
- Mallory Square
- Smathers Beach
- Ernest Hemingway Home and Museum
- Fort Zachary Taylor Historic State Park
- Clarence S. Higgs Memorial Beach Park
- Boca Chica Nude Beach
- Harry S. Truman Little White House
- Key West Lighthouse and Keeper's Quarters Museum
- Florida Keys National Marine Sanctuary
- Audubon House and Tropical Gardens
- Key West Shipwreck Museum
- Robbie's
