The Best Business Hotels in Key West, FL from ￥23,233 in 2026

A sunny street lined with historic buildings, a 'ONE WAY' sign, and a flagpole with flags.

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Our top choices for Key West business-friendly hotels

A pool area with lounge chairs and umbrellas, surrounded by palm trees.

An outdoor patio area with tables and chairs, a bar area with a counter and bar stools, and a TV mounted on the wall.

A wooden outdoor dining table set with glassware, candles, and lanterns, surrounded by lush greenery.

A hotel room with a large bed, a wooden nightstand, a desk, a chair, and a window with curtains.

1. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

New Town

Brian

￥19,768

￥26,683 total

includes taxes & fees

Oct 25 - Oct 26

A beach with a wooden pier, palm trees, and beach umbrellas.

A modern bar area with a central island, white bar stools, and a view of the ocean.

An outdoor dining area with tables and chairs, overlooking the ocean.

An outdoor dining area with tables set for guests, overlooking a calm sea and a pier.

2. The Reach Key West, Curio Collection by Hilton

Old Town Key West

Darlene

￥24,130

￥37,813 total

includes taxes & fees

Oct 27 - Oct 28

A deck with sun loungers and a railing overlooking the sea.

A poolside area with lounge chairs and umbrellas, palm trees, and a view of the sea.

A beachside hotel with rows of blue lounge chairs and white umbrellas, palm trees, and a clear blue sky.

A beach scene with two people relaxing under a white umbrella, a palm tree, and a clear blue sky.

3. Southernmost Beach Resort and Guesthouses

Old Town Key West

Jacob Stuart

￥27,543

￥42,542 total

includes taxes & fees

Oct 25 - Oct 26

A balcony with a view of a pool area, palm trees, and outdoor seating.

An outdoor patio area with tables and chairs, umbrellas, and palm trees.

A sign for Doubletree by Hilton Grand Key Resort surrounded by lush greenery and palm trees.

A large conference room with round tables, chairs, and a central carpeted area.

4. DoubleTree Resort by Hilton Grand Key - Key West

Key West

Nancy

￥18,836

￥26,524 total

includes taxes & fees

Oct 25 - Oct 26

A pool area with lounge chairs and umbrellas, surrounded by palm trees and a view of the ocean.

A bar area with a thatched roof, wooden chairs, and a poolside view.

A hotel room with a balcony, a bed, a desk, and two chairs.

A modern kitchen with a marble island, wooden cabinets, and pendant lighting.

5. Hampton Inn Key West FL

Key West

Erika

￥26,705

￥30,043 total

includes taxes & fees

Oct 25 - Oct 26

A large, white, two-story building with a balcony and a sign reading "The Marker Resort."

A covered outdoor area with a pool, palm trees, and lounge chairs.

A resort with a swimming pool, lounge chairs, umbrellas, and palm trees.

A marina with various boats docked, including a green and white boat named 'Jolly Roger'.

6. The Marker Key West Harbor Resort

Key West Historic District

Lynne

￥29,755

￥43,430 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel room with a large bed, a nightstand, a bedside table, and a bathroom visible through an open door.

A reception area with a wooden herringbone wall, teal chairs, a wooden bench, and two framed sunset paintings.

A breakfast table with various food items and drinks, a pool in the background, and a tiled wall.

A building with a sign reading "ALMOND Frog & Toad Inn" and a "VACANCY" sign below it.

7. Almond Tree Inn Hotel - Adults Only

Old Town Key West

Teresa

￥43,495

￥48,932 total

includes taxes & fees

Oct 25 - Oct 26

A pool area with lounge chairs and palm trees, surrounded by boats and a sunset in the background.

A hotel room with a large bed, a desk, a chair, a television, and a ceiling fan.

A restaurant with wooden tables and chairs, a counter with seafood signs, and large windows.

A balcony with a wooden table and chairs, overlooking a swimming pool and palm trees.

8. The Perry Hotel & Marina Key West

Stock Island

Jade

￥13,679

￥24,907 total

includes taxes & fees

Nov 2 - Nov 3

View all properties

Top Key West Hotel Reviews

Beachside Resort & Residences

10/10 Excellent

"The resort offers shuttle service into town which made it very easy to explore Key West."

DoubleTree Resort by Hilton Grand Key - Key West

10/10 Excellent

"Very nice, would stay again."

Hilton Garden Inn Key West / The Keys Collection

10/10 Excellent

"Clean room"

Southernmost Beach Resort and Guesthouses

10/10 Excellent

"Location, location, location! This resort is on the beach at the southern end of Duval St, next to the buoy. There are 4 pools, two of which have bars with wonderful, friendly tenders. The staff is enthusiastic and attentive."

Pier House Resort & Spa

10/10 Excellent

"Martina and Jolene were amazing at the bar. The place was very clean and the food was good."

The Reach Key West, Curio Collection by Hilton

8/10 Good

"The property was well maintained, and the staff was very friendly"

Ibis Bay Beach Resort

10/10 Excellent

"Todo maravillosamente genial"

Fairfield by Marriott Inn & Suites Key West at The Keys Collection

10/10 Excellent

"Staff was friendly and very helpful. Their shuttle to downtown was excellent"

Opal Key Resort & Marina, Key West

10/10 Excellent

"Never stayed at an Opal resort property before..but will return! Very impressive, great location and a great restaurant!"

Frequently asked questions

How much do business-friendly hotels in Key West cost?

You can expect to pay between ￥23,233 and ￥43,430 per night for business-friendly hotels in Key West. Epic deals on properties that cater to work-related guests are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in Key West?

Key West has multiple business-friendly hotels with a total average guest review rating of 8.9. One of the most popular is The Perry Hotel & Marina Key West. Put your laptop bag down and relax at this 4-stars option, which includes a garden and a dock. Corporate travelers also recommend Silver Palms Inn. It has a 3.5-stars rating and amenities such as pillow top mattresses and a swimming pool.

How many business-friendly hotels are there in Key West?

Key West has 41 hotels that cater to business travelers. Whether your ideal base is having a location closer to the city or amenities like conference rooms and workspaces, you'll find the perfect property on Expedia.

Are there any family-friendly hotels in Key West that are also business friendly?

Taking a trip with the family, and squeezing in some work, is a breeze at Eden House. Make use of amenities including a sauna and WiFi at this favorite 3.5-stars stay in Key West. Also look up Hyatt Centric Key West Resort and Spa. Finish your meetings and then spend quality time with your loved ones at this 4-stars option. A nearby beach and a cafe are two of the conveniences available here. Once you've wrapped up work, there are lots of family-friendly attractions to visit around Key West. Smathers Beach and South Beach guarantee a good time for young and old.

Are there any 5-star business-friendly hotels in Key West?

While there aren't any 5-star business-friendly hotels in Key West, there are some fab 4-star options to select from. Take a look at The Perry Hotel & Marina Key West, located around 6 kilometers from downtown. This stylish stay comes with conveniences like beauty services and a swimming pool. Ocean Key Resort - A Noble House Resort is another 4-star property that caters to those traveling on business. Around 0.80 kilometers from the heart of Key West, it features beauty services and designer toiletries.

Why book your business-friendly hotel in Key West with Expedia?

With top amenities like conference rooms, housekeeping and free parking, our business-friendly accommodations come with everything you'll need to complete the job — and then unwind! Enter your preferred dates and travel destination and we'll help you do the rest.

How can I find cheap business-friendly hotels in Key West?

Expedia can help you easily locate cheap business-friendly hotels in Key West. Simply go to the "traveler experience" filter and click on "business friendly." This will show you properties with amenities designed to help you work and rest comfortably, like free WiFi and included breakfast. You can also choose your budget and hotel star rating to keep costs down.

What is there to do in Key West near my business-friendly hotel?

Key West has enough sights to keep you hopping for weeks, beginning with Smathers Beach. South Beach, Clarence S. Higgs Memorial Beach Park and Boca Chica Nude Beach are other popular attractions. If the business deals are done and you have time to spare, Key West Aquarium and Harry S. Truman Little White House are nice final touches to your itinerary.

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Check availability on Key West Business Hotels

Our top choices for Key West business-friendly hotels

1. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

2. The Reach Key West, Curio Collection by Hilton

3. Southernmost Beach Resort and Guesthouses