Photo by Sophia Field

Find hotels in Sant' Ambrogio, Florence from ¥8,868

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Discover 494 Sant' Ambrogio hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Bavaria

1.0 star property
8.2 out of 10, Very Good, (390)
"Lovely hotel in a historical building. "
The price is ¥11,663
¥14,035 total
includes taxes & fees
Aug 24 - Aug 25
Hotel Bavaria

Residenza d'Epoca White Room

7.8 out of 10, Good, (52)
"The location was great, close to so many things. Be prepared to walk up a few flights of stairs, as long as you know whsts coming it is totally worth the climb. "
Residenza d'Epoca White Room

Palazzo dei Ciompi Suites

7.6 out of 10, Good, (385)
"We loved this property, it looked exactly like the photos, the room was very clean, spacious and beautiful. My partner and I had such a wonderful time. Staff was incredible at the front desk with any questions we had as well as booking us a taxi for our early morning train when we left. This hotel was walkable to many incredible restaurants as well as the Duomo in Florence. We will be recommending this Hotel to anyone traveling through Florence. "
Palazzo dei Ciompi Suites

Locanda Orchidea - B&B

9.2 out of 10, Wonderful, (219)
"Convenience"
Locanda Orchidea - B&B

Residenza D'Epoca Sant'Egidio

7.2 out of 10, Good, (85)
"Absolutely loved our stay here. The terrace French doors and the high ceilings made me feel like I a Victorian princess. I loved opening the doors and the patio doors for the view and for breeze. There are stairs to the property and you have to check in a bloc or two away so be prepared to walk but with the stairs came a ton of safety!!! Four locks to get through. Felt super safe here. I also loved how we were in the heart of Florence but from the back patio it was so quiet you didn’t hear any...
The price is ¥8,868
¥11,822 total
includes taxes & fees
Aug 31 - Sep 1
Residenza D'Epoca Sant'Egidio

Hotel Rita Major

2.0 star property
9.2 out of 10, Wonderful, (140)
"Wonderful, spacious room which was clean and comfortable. Staff were lovely and breakfast was great. Location was good for walking and catching transport. Highly recommend."
The price is ¥16,784
¥20,012 total
includes taxes & fees
Sep 1 - Sep 2
Hotel Rita Major

Hotel Dalì

1.0 star property
8.6 out of 10, Excellent, (874)
"Great staff and location."
The price is ¥18,791
¥21,876 total
includes taxes & fees
Aug 18 - Aug 19
Hotel Dalì

Iris Apartments by Mmega

7.8 out of 10, Good, (12)
"Excellent location bit a bit noisy at night."
The price is ¥14,595
¥31,902 total
includes taxes & fees
Aug 18 - Aug 19
Iris Apartments by Mmega

Hotel Bodoni

2.0 star property
8.2 out of 10, Very Good, (749)
"Good location.And very enjoy the morning view."
The price is ¥12,557
¥15,362 total
includes taxes & fees
Aug 24 - Aug 25
Hotel Bodoni

Mamo Florence - Dante & Virgilio Apartments

10.0 out of 10, Exceptional, (6)
"Great location"
The price is ¥18,195
¥39,306 total
includes taxes & fees
Aug 18 - Aug 19
Mamo Florence - Dante & Virgilio Apartments

B&B di Piazza del Duomo

9.0 out of 10, Wonderful, (211)
"I like the place here, very affordable price and also friendly staffs. We enjoyed staying in Florence, beautiful it’s the most iconic sights architecture and culture. "
B&B di Piazza del Duomo

Florence Central Suites by MMega

The price is ¥14,230
¥48,726 total
includes taxes & fees
Aug 18 - Aug 19
Florence Central Suites by MMega

Dimora del Cardinale - Residenza d'epoca

10.0 out of 10, Exceptional, (52)
"The location of this property is perfect. The room mas clean and had a lot of personality. Would 100% stay here again"
The price is ¥19,571
¥23,595 total
includes taxes & fees
Aug 21 - Aug 22
Dimora del Cardinale - Residenza d'epoca

Numa Florence Palazzo Haggis

9.0 out of 10, Wonderful, (2)
The price is ¥20,576
¥24,701 total
includes taxes & fees
Aug 18 - Aug 19
Numa Florence Palazzo Haggis

Guest house Biffi Simone

9.6 out of 10, Exceptional, (12)
"Will visit again 10/10"
Guest house Biffi Simone

Mamo Florence - Geordie Apartment

8.0 out of 10, Very Good, (2)
The price is ¥15,139
¥35,945 total
includes taxes & fees
Aug 31 - Sep 1
Mamo Florence - Geordie Apartment

Wine Apartments Florence Ansonica

8.6 out of 10, Excellent, (4)
"Pros: Exactly like the pictures. Friendly and responsive staff. Everything works. Washer in apartment. Market nearby. Cons: bed bugs (totally unacceptable!), noisy district, drunks roaming streeets."
Wine Apartments Florence Ansonica

Santa Croce's Vintage by MMega

The price is ¥10,728
¥44,873 total
includes taxes & fees
Aug 18 - Aug 19
Santa Croce's Vintage by MMega

Mamo Florence - Minnesota Apartment

The price is ¥12,794
¥31,643 total
includes taxes & fees
Aug 27 - Aug 28
Mamo Florence - Minnesota Apartment

Mamo Florence - Donatello Apartment

The price is ¥17,184
¥36,472 total
includes taxes & fees
Aug 22 - Aug 23
Mamo Florence - Donatello Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most.
Historic Centre of Florence map

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo map

Duomo

Framed by a magnificent cathedral and charming streets lined with churches and restaurants, this neighborhood rests at the very heart of Florence.

Santa Maria Novella map

Santa Maria Novella

Spend some time in an attractive neighborhood close to the city center that encompasses ancient buildings and churches and a large park of outstanding beauty.

San Giovanni map

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

Santa Croce map

Santa Croce

One of the historic districts of Florence has a network of medieval streets lined with opulent churches, leather stores, markets and atmospheric restaurants.

Top Sant' Ambrogio Hotel Reviews

Frequently asked questions

What's it like in Sant' Ambrogio?

Guests are sure to enjoy their time checking out all that Florence's Sant' Ambrogio neighborhood has to offer. Be sure to check out Great Synagogue of Florence and Piazza Massimo D'Azeglio as part of your Sant' Ambrogio travel plans.

What's the best accommodation in Sant' Ambrogio?

Based on Expedia customer reviews, Dimora del Cardinale - Residenza d'epoca is the highest ranked property in Sant' Ambrogio. This B&B is a short 7-minute walk from Cathedral of Santa Maria del Fiore, and it offers free WiFi and comfy beds. Other favorite options in the area include Alfieri9 and Hotel Regency.

How many hotels will I find in Sant' Ambrogio?

If you're searching for places to stay in Florence, Expedia has something to meet your needs with 494 Sant' Ambrogio hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Sant' Ambrogio, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable provided that you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review top deals in Sant' Ambrogio.

Where can I learn more about changing or cancelling my trip to Sant' Ambrogio?

To find more details about rescheduling or cancelling your trip to Sant' Ambrogio, head over to our customer service page.

What is there to do around this Florence neighborhood?

Landmarks in Sant' Ambrogio that you won't want to miss include Great Synagogue of Florence and Church of Santa Maria Maddalena dei Pazzi. Piazza Massimo D'Azeglio and Jewish Museum are also a couple of places to visit in the neighborhood. Cathedral of Santa Maria del Fiore and Uffizi Gallery are some favorite places to visit in the area around Sant' Ambrogio. When you're sightseeing in Florence, Church of Sant'Ambrogio and FiesoleBike Day Tours are also worth a stop.