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Oct 16 - Oct 18
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Oct 23 - Oct 25

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Our top choices for Sant' Ambrogio hotels

An outdoor patio with tables and chairs, surrounded by greenery and a pergola with lights.

1. Hotel Regency

Hotel Regency
5.0 star property
Sant' Ambrogio
9.4 out of 10, Exceptional, (465 reviews)
"Great hotel. About 20 min walk to the duomo"
United States
Dylan
The price is ￥52,712
￥60,820 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Regency
A spacious lobby with high ceilings, arched windows, and a variety of seating arrangements including sofas and chairs.

2. The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
5.0 star property
Sant' Ambrogio
10.0 out of 10, Exceptional, (26 reviews)
"Lovely stay. Highly recommend it!"
United States
GOLNAZ
The price is ￥90,213
￥102,072 total
includes taxes & fees
Nov 9 - Nov 10
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
A hotel room with a large bed, two bedside tables, a headboard with a mural, and a window with curtains.

3. Palazzo Monnalisa

Palazzo Monnalisa
4.0 star property
Sant' Ambrogio
9.0 out of 10, Wonderful, (810 reviews)
"We loved our stay! The breakfast was amazing"
United States
Laura
The price is ￥47,245
￥54,451 total
includes taxes & fees
Oct 18 - Oct 19
Palazzo Monnalisa
A hotel room with a bed, pillows, a wall-mounted lamp, and a framed picture.

4. Anchor Santa Croce

Anchor Santa Croce
Sant' Ambrogio
9.8 out of 10, Exceptional, (7 reviews)
"Staff was very helpful and attentive. Location was perfect, within walking distance to many restaurants, piazza’s, shops."
United States
Franie
The price is ￥20,892
￥25,109 total
includes taxes & fees
Nov 6 - Nov 7
Anchor Santa Croce
A rectangular pool with wooden deck and lounge chairs, surrounded by greenery and a white wall.

5. Villa Tortorelli

Villa Tortorelli
Sant' Ambrogio
9.4 out of 10, Exceptional, (89 reviews)
"The staff was excellent and very friendly. Breakfast was great with lots of choices, and the room was nice and large. The pool was a great spot and rare to find in other places in this area Only con is that the check in instructions can be difficult to find/follow, and there is no staff present after 3pm so it’s all self service."
United States
Raul
The price is ￥20,373
￥24,539 total
includes taxes & fees
Nov 10 - Nov 11
Villa Tortorelli
An open balcony with a table and two chairs, a view of a garden with various plants and flowers, and a white door frame.

6. Hotel Villa Liana

Hotel Villa Liana
3.0 star property
Sant' Ambrogio
8.8 out of 10, Excellent, (371 reviews)
"A vey beautiful place, the people are very friendly, and the breakfast is really good."
Mexico
Emilio
The price is ￥16,341
￥20,103 total
includes taxes & fees
Nov 10 - Nov 11
Hotel Villa Liana
A hallway with a red sofa, a large mirror, and a lamp.

7. Dimora del Cardinale - Residenza d'epoca

Dimora del Cardinale - Residenza d'epoca
Sant' Ambrogio
9.8 out of 10, Exceptional, (79 reviews)
"My stay here was so relaxing and exactly what I needed to recharge while enjoying my stay in Florence."
United States
Holly
The price is ￥18,420
￥22,390 total
includes taxes & fees
Nov 10 - Nov 11
Dimora del Cardinale - Residenza d'epoca
A person serving at an outdoor café with multiple tables and chairs, surrounded by greenery.

8. Hotel Bodoni

Hotel Bodoni
2.0 star property
Sant' Ambrogio
8.2 out of 10, Very good, (880 reviews)
"great stay"
Canada
Ethan
The price is ￥11,316
￥14,044 total
includes taxes & fees
Nov 8 - Nov 9
Hotel Bodoni
A room with a bed, a TV, a sofa, a staircase, and a view of greenery outside.

9. Firenze Suite

Firenze Suite
Sant' Ambrogio
10.0 out of 10, Exceptional, (5 reviews)
"Everything was great"
United States
Chris
The price is ￥21,266
￥25,520 total
includes taxes & fees
Nov 10 - Nov 11
Firenze Suite
A room with a fireplace, bookshelves, framed pictures, and a window with a view of buildings.

10. Alfieri9

Alfieri9
3.0 star property
Sant' Ambrogio
9.6 out of 10, Exceptional, (175 reviews)
"Staff fantastic, clean and beautiful room, lovely fresh breakfast. Great stay , would definitely recommend . "
United Kingdom
Paul
The price is ￥15,025
￥18,655 total
includes taxes & fees
Nov 10 - Nov 11
Alfieri9
A courtyard with purple wisteria vines, potted red and white flowers, and a building with green shutters.

11. Locanda Orchidea - B&B

Locanda Orchidea - B&B
Sant' Ambrogio
9.2 out of 10, Wonderful, (259 reviews)
"Great place"
United States
Patricio
The price is ￥13,996
￥17,523 total
includes taxes & fees
Nov 8 - Nov 9
Locanda Orchidea - B&B
A modern bathroom with a bathtub, a large mirror, and a television.

12. Palazzo dei Ciompi Suites

Palazzo dei Ciompi Suites
Sant' Ambrogio
7.6 out of 10, Good, (418 reviews)
"Very near to all attractions. And places to eat. Safe place and very nice place"
United States
Mrudula
The price is ￥10,977
￥14,203 total
includes taxes & fees
Nov 10 - Nov 11
Palazzo dei Ciompi Suites
A corner with a potted plant, a small table with books and headphones, and a bench.

13. Numa Florence Fiesolana

Numa Florence Fiesolana
Sant' Ambrogio
7.4 out of 10, Good, (3 reviews)
"Great"
United States
Charleston
The price is ￥21,601
￥25,889 total
includes taxes & fees
Nov 12 - Nov 13
Numa Florence Fiesolana
A bedroom with a bed, a chair, a wardrobe, and a window with curtains.

14. Gramsci Apartment by Mamo Florence

Gramsci Apartment by Mamo Florence
Sant' Ambrogio
10.0 out of 10, Exceptional, (2 reviews)
"The apartment is in a good location and really easy to find with the instructions. There was only 3 of us so plenty of space. The beds were comfy, the apartment was clean and even though it’s right on a main road, you couldn’t hear anything from the inside. The only thing was the hot water in the main bathroom was hit and miss. Sometimes showers would be cold, other times there was hot water. The en suite always had hot water. The AC in the living room didn’t feel as cold as the temperature was...
United Kingdom
Rebekah
The price is ￥13,925
￥36,950 total
includes taxes & fees
Nov 11 - Nov 12
Gramsci Apartment by Mamo Florence
A room with a dining table, chairs, a sofa, a lamp, a TV, and a window with curtains.

15. Tosca

Tosca
Sant' Ambrogio
10.0 out of 10, Exceptional, (3 reviews)
"Very clean property, very good communication Good place 👌"
United States
Manolo
The price is ￥10,379
￥18,510 total
includes taxes & fees
Nov 2 - Nov 3
Tosca
A spa room with a hot tub, wooden bench, and a wooden chair.

16. PALAZZO TESTA - LOCAZIONE TURISTICA

PALAZZO TESTA - LOCAZIONE TURISTICA
Sant' Ambrogio
10.0 out of 10, Exceptional, (1 review)
"Great place to stay good location"
United Kingdom
ian
The price is ￥15,300
￥18,958 total
includes taxes & fees
Nov 8 - Nov 9
PALAZZO TESTA - LOCAZIONE TURISTICA
A living room with a sofa, a table, chairs, a fireplace, and a stone wall.

17. Alina Apartment by Mamo Florence

Alina Apartment by Mamo Florence
Sant' Ambrogio
10.0 out of 10, Exceptional, (1 review)
"The property is up three flights of stairs so you need your muscles. But once in, the property feels like home. Ample room for dining and living, and Mamo Apartments couldn't have been more helpful. Tha apartment is located in a good position in town, amenities are excellent. Air conditioners work yet you are able to open windows and feel safe. The area is lively and there is a bit of noise late at night. Coffee is next door downstairs and the owner is lovely. Great place to stay."
Australia
Lee
The price is ￥18,751
￥37,826 total
includes taxes & fees
Oct 23 - Oct 24
Alina Apartment by Mamo Florence
A dining area with tables and chairs, a fireplace, and a large mural on the wall.

18. I Quattro Poeti

I Quattro Poeti
Sant' Ambrogio
8.4 out of 10, Very good, (172 reviews)
"We like our stay and the location is good."
Sweden
joegie
The price is ￥12,763
￥16,168 total
includes taxes & fees
Nov 11 - Nov 12
I Quattro Poeti
A balcony with potted flowers and a view of a historic building with a dome.

19. B&B di Piazza del Duomo

B&B di Piazza del Duomo
Sant' Ambrogio
9.2 out of 10, Wonderful, (297 reviews)
"Wonderful location and spacious room with a balcony with a direct view of the Duomo. AC worked great and the staff provided excellent service."
United States
Ifthikar
The price is ￥21,622
￥25,912 total
includes taxes & fees
Nov 4 - Nov 5
B&B di Piazza del Duomo
Exterior

20. Casa Rovai Guest House

Casa Rovai Guest House
Sant' Ambrogio
8.6 out of 10, Excellent, (121 reviews)
"Amazing location, friendly staff, appreciated being able to keep our luggage there + having a water station."
Canada
John
The price is ￥19,025
￥23,055 total
includes taxes & fees
Nov 5 - Nov 6
Casa Rovai Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Sant' Ambrogio

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A spacious lobby with high ceilings, arched windows, and a variety of seating arrangements including sofas and chairs.
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
5.0 star property
10.0
Exceptional
26 reviews
View
An outdoor patio with tables and chairs, surrounded by greenery and a pergola with lights.
Hotel Regency
5.0 star property
9.4
Exceptional
465 reviews
View
A hotel room with a large bed, two bedside tables, a headboard with a mural, and a window with curtains.
Palazzo Monnalisa
4.0 star property
9.0
Wonderful
810 reviews
View
An open balcony with a table and two chairs, a view of a garden with various plants and flowers, and a white door frame.
Hotel Villa Liana
3.0 star property
8.8
Excellent
371 reviews
View
Outdoor dining
Milu Firenze
3.0 star property
7.8
Good
66 reviews
View

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most.
A river with buildings on the right bank.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Florence.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Piazza del Duomo and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

A grand cathedral with intricate architectural details, including statues and ornate decorations.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Sant' Ambrogio Hotel Reviews

I Quattro Poeti

I Quattro Poeti

8/10 Good
"The stairs is 4th floor , not 3 rd , it’s hard with luggage , good is cross street is a laundry mat , it closed at 8 pm , the only thing I cannot give 5 star is stairs . Room is spacious and mine is with nice view I arrived at 230 pm , I use WhatsApp talk w staff , they show me how to open key box , it’s good"
Diana 3-night trip
Posted 22 hours ago
I Quattro Poeti

Frequently asked questions

What's it like in Sant' Ambrogio?
Guests are sure to enjoy their time checking out all that Florence's Sant' Ambrogio neighborhood has to offer. Be sure to check out Piazza Massimo D'Azeglio and Church of Santa Maria Maddalena dei Pazzi as part of your Sant' Ambrogio travel plans.
What's the best accommodation in Sant' Ambrogio?
Based on our traveler data, Hotel Bodoni is one of the top choices for your stay in Sant' Ambrogio. This hotel is a short 7-minute walk from Piazza del Duomo, and it offers free breakfast and a bar. Other good options for your stay in the neighborhood include Hotel Bavaria and Hotel Regency.
How many hotels will I find in Sant' Ambrogio?
If you're searching for places to stay in Florence, Expedia has something to meet your needs with 549 Sant' Ambrogio hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Sant' Ambrogio, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review top deals in Sant' Ambrogio.
Where can I learn more about changing or cancelling my trip to Sant' Ambrogio?
To find more details about rescheduling or cancelling your trip to Sant' Ambrogio, head over to our customer service page.
What is there to do around this Florence neighborhood?
Landmarks in Sant' Ambrogio that you won't want to miss include Great Synagogue of Florence and Church of Santa Maria Maddalena dei Pazzi. Piazza Massimo D'Azeglio and Mercato di Sant'Ambrogio are also a couple of places to visit in the neighborhood. Piazza del Duomo and Piazza di Santa Maria Novella are some favorite places to visit in the area around Sant' Ambrogio. When you're sightseeing in Florence, Jewish Museum and FiesoleBike Day Tours are also worth a stop.

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