Photo by Sophia Field

Find hotels in Sant' Ambrogio, Florence from ￥7,801

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 29 - Aug 30
Tomorrow
Aug 30 - Aug 31
This weekend
Aug 29 - Aug 31
Next weekend
Sep 5 - Sep 7

Filter by

Guest rating
Guest rating
Star rating

Discover 492 Sant' Ambrogio hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Sant' Ambrogio hotels

Art Hotel Villa Agape
Exterior detail

Art Hotel Villa Agape

4.0 star property
9.8 out of 10, Exceptional, (1004)
"Comfortable bed, amazing views, wonderful staff."
The price is ￥40,756
￥47,233 total
includes taxes & fees
Sep 1 - Sep 2
Art Hotel Villa Agape
Wyndham Garden Florence
Daily buffet breakfast (EUR 15 per person)

Wyndham Garden Florence

4.0 star property
8.6 out of 10, Excellent, (518)
"Lovely place to stay very nice staff rooms where lovely "
The price is ￥7,801
￥10,985 total
includes taxes & fees
Aug 31 - Sep 1
Wyndham Garden Florence
Hotel Collodi
Rooftop terrace

Hotel Collodi

2.0 star property
9.6 out of 10, Exceptional, (930)
"Great location, Spacious Room, Nice rooftop, Friendly Service!"
The price is ￥15,266
￥18,336 total
includes taxes & fees
Aug 30 - Aug 31
Hotel Collodi
B&B di Piazza del Duomo
Deluxe Double Room, Non Smoking, Ensuite (Vista Duomo) | In-room safe, blackout drapes, soundproofing, free WiFi

B&B di Piazza del Duomo

9.0 out of 10, Wonderful, (212)
"I like the place here, very affordable price and also friendly staffs. We enjoyed staying in Florence, beautiful it’s the most iconic sights architecture and culture. "
B&B di Piazza del Duomo
Locanda Orchidea - B&B
Daily buffet breakfast (EUR 7.00 per person)

Locanda Orchidea - B&B

9.2 out of 10, Wonderful, (219)
"Convenience"
Locanda Orchidea - B&B
Hotel Bavaria
Interior entrance

Hotel Bavaria

1.0 star property
8.2 out of 10, Very Good, (392)
"Lovely hotel in a historical building. "
The price is ￥12,600
￥15,062 total
includes taxes & fees
Aug 30 - Aug 31
Hotel Bavaria
Ciompi Prestige by Mmega
Premium Apartment | Living area | 40-inch flat-screen TV with digital channels, TV

Ciompi Prestige by Mmega

9.0 out of 10, Wonderful, (2)
The price is ￥27,268
￥49,219 total
includes taxes & fees
Sep 4 - Sep 5
Ciompi Prestige by Mmega
Iris Apartments by Mmega
City view

Iris Apartments by Mmega

7.8 out of 10, Good, (12)
"Excellent location bit a bit noisy at night."
The price is ￥16,361
￥33,788 total
includes taxes & fees
Aug 30 - Aug 31
Iris Apartments by Mmega
Hotel Bodoni
Restaurant

Hotel Bodoni

2.0 star property
8.2 out of 10, Very Good, (752)
"Good location.And very enjoy the morning view."
The price is ￥16,416
￥19,600 total
includes taxes & fees
Sep 2 - Sep 3
Hotel Bodoni
Hotel Villa Liana
Interior entrance

Hotel Villa Liana

3.0 star property
8.6 out of 10, Excellent, (330)
"Very nice, clean large room, friendly staff. The building has an authentic Tuscan charm of 19th century. Very good breakfast. Walking distance from all the main sights of Florence e.g. Santa Maria de Florine. "
Hotel Villa Liana
Hotel Rita Major
Garden

Hotel Rita Major

2.0 star property
9.2 out of 10, Wonderful, (142)
"Wonderful, spacious room which was clean and comfortable. Staff were lovely and breakfast was great. Location was good for walking and catching transport. Highly recommend."
The price is ￥14,729
￥17,745 total
includes taxes & fees
Sep 1 - Sep 2
Hotel Rita Major
Dimora del Cardinale - Residenza d'epoca
Classic Room | Terrace/patio

Dimora del Cardinale - Residenza d'epoca

10.0 out of 10, Exceptional, (53)
"Most memorable magical stay staff was extremely helpful. Place was beautiful beyond our expectations area was perfect to walk to everything. Highly recommend this location. "
The price is ￥22,063
￥26,329 total
includes taxes & fees
Aug 30 - Aug 31
Dimora del Cardinale - Residenza d'epoca
I Quattro Poeti
Exterior

I Quattro Poeti

8.8 out of 10, Excellent, (146)
"Great location and nice room. Great communication from agents "
I Quattro Poeti
Residenza D'Epoca Sant'Egidio
Property entrance

Residenza D'Epoca Sant'Egidio

7.2 out of 10, Good, (85)
"Absolutely loved our stay here. The terrace French doors and the high ceilings made me feel like I a Victorian princess. I loved opening the doors and the patio doors for the view and for breeze. There are stairs to the property and you have to check in a bloc or two away so be prepared to walk but with the stairs came a ton of safety!!! Four locks to get through. Felt super safe here. I also loved how we were in the heart of Florence but from the back patio it was so quiet you didn’t hear any...
The price is ￥12,892
￥16,239 total
includes taxes & fees
Aug 30 - Aug 31
Residenza D'Epoca Sant'Egidio
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
Lobby lounge

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

5.0 star property
10.0 out of 10, Exceptional, (2)
"This truly is a boutique hotel - the staff, the attention to detail, the design made for such a wonderful curated experience and memorable stay. We were made to feel so welcome, Manuela the manager is extraordinary! We didn't want to leave and will most certainly be back. "
The price is ￥83,676
￥94,789 total
includes taxes & fees
Aug 31 - Sep 1
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
Borgo Pinti Cozy Flat 
Apartment, 2 Bedrooms | Private kitchen | Full-size fridge, microwave, oven, stovetop

Borgo Pinti Cozy Flat 

9.0 out of 10, Wonderful, (2)
"Excellent property beyond our expectations. After a stressful day of traveling internationally, the key and entry taxed us. The key continued to be an issue for us (skeleton key with 4 locks). But otherwise, it's location and the property itself, awesome!"
The price is ￥30,649
￥46,931 total
includes taxes & fees
Sep 12 - Sep 13
Borgo Pinti Cozy Flat 
Alfieri9
Daily buffet breakfast (EUR 8 per person)

Alfieri9

3.0 star property
9.6 out of 10, Exceptional, (148)
"Room was very comfortable and a short walk away from attractions "
Alfieri9
Gramsci Apartment by Mamo Florence
Apartment | 2 bedrooms, iron/ironing board, free WiFi

Gramsci Apartment by Mamo Florence

The price is ￥23,449
￥46,735 total
includes taxes & fees
Sep 2 - Sep 3
Gramsci Apartment by Mamo Florence
Hotel D'Azeglio
Exterior

Hotel D'Azeglio

2.0 star property
7.8 out of 10, Good, (330)
"Clean place, friendly and helpful staff. Wish they had elevators."
The price is ￥15,166
￥18,228 total
includes taxes & fees
Aug 30 - Aug 31
Hotel D'Azeglio
Florence Central Suites by MMega
Apartment | Private kitchen | Fridge, stovetop, cookware/dishes/utensils

Florence Central Suites by MMega

The price is ￥11,910
￥30,609 total
includes taxes & fees
Aug 31 - Sep 1
Florence Central Suites by MMega
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most.
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

Framed by a magnificent cathedral and charming streets lined with churches and restaurants, this neighborhood rests at the very heart of Florence.

Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

Spend some time in an attractive neighborhood close to the city center that encompasses ancient buildings and churches and a large park of outstanding beauty.

Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

Piazza Santa Croce showing a city and street scenes

Santa Croce

One of the historic districts of Florence has a network of medieval streets lined with opulent churches, leather stores, markets and atmospheric restaurants.

Top Sant' Ambrogio Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Sant' Ambrogio?

Guests are sure to enjoy their time checking out all that Florence's Sant' Ambrogio neighborhood has to offer. Be sure to check out Great Synagogue of Florence and Piazza Massimo D'Azeglio as part of your Sant' Ambrogio travel plans.

What's the best accommodation in Sant' Ambrogio?

Based on Expedia customer reviews, Dimora del Cardinale - Residenza d'epoca is the highest ranked property in Sant' Ambrogio. This B&B is a short 7-minute walk from Cathedral of Santa Maria del Fiore, and it offers free WiFi and comfy beds. Other favorite options in the area include Alfieri9 and Hotel Regency.

How many hotels will I find in Sant' Ambrogio?

If you're searching for places to stay in Florence, Expedia has something to meet your needs with 494 Sant' Ambrogio hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Sant' Ambrogio, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable provided that you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review top deals in Sant' Ambrogio.

Where can I learn more about changing or cancelling my trip to Sant' Ambrogio?

To find more details about rescheduling or cancelling your trip to Sant' Ambrogio, head over to our customer service page.

What is there to do around this Florence neighborhood?

Landmarks in Sant' Ambrogio that you won't want to miss include Great Synagogue of Florence and Church of Santa Maria Maddalena dei Pazzi. Piazza Massimo D'Azeglio and Jewish Museum are also a couple of places to visit in the neighborhood. Cathedral of Santa Maria del Fiore and Uffizi Gallery are some favorite places to visit in the area around Sant' Ambrogio. When you're sightseeing in Florence, Church of Sant'Ambrogio and FiesoleBike Day Tours are also worth a stop.