Sant' Ambrogio Vacations from ￥484,132
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The Latest Sant' Ambrogio Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Palazzo Firenze by Baglioni Hotels & Resorts
Historic Centre of Florence
￥886,714
per person
Sep 17 - Sep 24
found 8 hours ago
Roundtrip flight included
Tokyo (HND) to Florence (FLR)
9.4/10 Exceptional! (239 reviews)
L’hôtel est sensationnel et le service offert par le personnel est impeccable. Merci !
Reviewed on Aug 1, 2026
Where to stay in Sant' Ambrogio
Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most. Learn more about Sant' Ambrogio
Historic Centre of Florence
10 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Duomo
Piazza del Duomo and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
Santa Croce
Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.
Sant' Ambrogio Hotel Deals
Hotel Regency
Piazza M. D'Azeglio, 3 Florence FI
Fully refundableReserve now, pay when you stay
￥55,133
￥63,595 total
Aug 20 - Aug 21
includes taxes & fees
Hotel Bodoni
Via Martiri del Popolo, 27 Florence FI
Fully refundableReserve now, pay when you stay
￥14,184
￥17,262 total
Aug 18 - Aug 19
includes taxes & fees
8.2/10 Very Good! (857 reviews)
"Great location close to everything with plenty of good restaurants, trattorias etc nearby. The breakfast was spot on for a great start to each day. The lift was a must as there was plenty of up and down different levels required as the reception dining area was on the top floor. Friendly and very ..."
Reviewed on Aug 17, 2026
Hotel Bavaria
Borgo Albizi 26 Florence FI
Fully refundableReserve now, pay when you stay
￥12,449
￥14,984 total
Aug 24 - Aug 25
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Sant Ambrogio vacation package cost?
Maybe less than you might think — from just ￥484,132, in fact! By combining hotels, flights and car rentals into your own custom-built travel package, your getaway to Sant Ambrogio is only clicks away.
How do I get a cheap travel package to Sant Ambrogio?
Combining your flight and hotel with Expedia won't just save precious time — it'll save you a nice amount too. A Sant Ambrogio vacation package makes it simple to arrange your perfect trip. With more than 550 airlines throughout the world to choose from, finding flights that suit your busy schedule won't be hard. On top of that, we've got over 1,000,000 hotel options globally to choose from. Talk about choice! No matter who you are, Expedia can show you the world.
Where should I stay in Sant Ambrogio?
A trip to Sant Ambrogio isn't complete until you've seen Cathedral of Santa Maria del Fiore and Ponte Vecchio. Book somewhere nearby for easy access to these popular attractions.
What are the top hotels in Sant Ambrogio?
Reserve a room at New Alfani. It's one of the area's most popular hotels. Another reputable option in Sant Ambrogio is Wine Apartments Florence Sangiovese.
How far in advance should I book my Sant Ambrogio vacation?
Travelers are generally able to compare international airfares on Expedia within 12 months of departure. Booking at the last minute? With a bit of luck, it's still possible to purchase an affordable ticket only weeks before your flight.
What does an Expedia Sant Ambrogio travel package include?
Expedia has everything you need to organize your Sant Ambrogio trip, but what your package looks like is your call. Choose from any combination of flights, hotels and rental cars. Searching for some activities to keep you on the move? Once you've made your booking, you can add them too. No matter your budget or style, there's a package deal to match your needs.
What should I know before booking a Sant Ambrogio travel package?
A travel package can be more affordable than individually booking everything you need for your escape. For example, combine your flights, hotels and rental cars and save a pretty penny. Whatever kind of vacation you're planning, you'll find a package that fits your budget.
Can I choose my airline with a Sant Ambrogio Expedia vacation package?
Yes, the choice is yours. We have access to over 550 airlines throughout the world, so you can tailor your Sant Ambrogio vacation according to your budget and needs.
If I'm not able to travel, can I cancel my Sant Ambrogio vacation package?
Don't worry if you're rethinking your Sant Ambrogio vacation package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We realize life can sometimes throw you a curveball, so look up our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.
Stay near popular Sant' Ambrogio attractions
Great Synagogue of Florence
9.0/10 (6 reviews)
Great Synagogue of Florence is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Experience the fascinating museums and acclaimed art scene in this vibrant area.
Church of Sant'Ambrogio
9.0/10 (13 reviews)
After visiting Church of Sant'Ambrogio, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or visit the churches in this vibrant area.
Mercato di Sant'Ambrogio
10.0/10 (1 review)
You can browse for the perfect souvenirs at Mercato di Sant'Ambrogio during your trip to Florence. Discover the fascinating museums and notable monuments in this vibrant area.
Piazza Massimo D'Azeglio
Find out about the history of Florence when you take a trip to Piazza Massimo D'Azeglio. Stroll along the riverfront or visit the notable monuments in this vibrant area.
Piazza Donatello
You can learn about the history of Florence with a stop at Piazza Donatello. Stroll along the riverfront or visit the churches in this vibrant area.
Church of Santa Maria Maddalena dei Pazzi
8.0/10 (2 reviews)
You can learn about the history of Florence when you stop by Church of Santa Maria Maddalena dei Pazzi. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Jewish Museum
8.8/10 (16 reviews)
You can study the exhibits at Jewish Museum, a museum with a storied past, during your trip to Florence. Experience the fascinating museums and acclaimed art scene in this vibrant area.
FiesoleBike Day Tours
You can take time to visit FiesoleBike Day Tours during your travels to Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.
Things to do
City Sightseeing Florence Hop-on Hop-off Bus Tour
￥4,536
per adult
76% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
￥21,532
per adult
100% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
￥3,322
per adult
80% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.