Photo by Michele Butts

Find hotels in La Mesa, CA from ¥10,755

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Compare 7,746 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Exterior
Wyndham San Diego Bayside
4.0 star property
8.2 out of 10, Very Good, (5884)
"The room was veeery dusty "
The price is ¥23,770
¥26,788 total
includes taxes & fees
May 27 - May 28
Wyndham San Diego Bayside
Aerial view
Paradise Point Resort & Spa
4.0 star property
8.4 out of 10, Very Good, (1814)
"We absolutely enjoyed celebrating our anniversary here!"
The price is ¥34,370
¥45,783 total
includes taxes & fees
May 27 - May 28
Paradise Point Resort & Spa
Lobby
Wyndham Garden San Diego Near SeaWorld
3.0 star property
7.2 out of 10, Good, (2627)
"It was convenient to airport and shopping."
The price is ¥18,591
¥20,951 total
includes taxes & fees
May 15 - May 16
Wyndham Garden San Diego Near SeaWorld
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Aerial view
The Dana on Mission Bay
3.5 star property
8.6 out of 10, Excellent, (2431)
"Love that it’s family friendly!"
The price is ¥27,965
¥31,516 total
includes taxes & fees
May 16 - May 17
The Dana on Mission Bay
Exterior
Omni San Diego Hotel
4.0 star property
9.0 out of 10, Wonderful, (1901)
"Great hotel to stay at to catch a baseball game. Close to restaurants. "
The price is ¥32,654
¥42,083 total
includes taxes & fees
May 15 - May 16
Omni San Diego Hotel
Pool
California Suites Hotel
2.0 star property
7.0 out of 10, Good, (1319)
"Everything was nice"
The price is ¥15,373
¥17,294 total
includes taxes & fees
May 15 - May 16
California Suites Hotel
Outdoor pool, sun loungers
Hilton San Diego Bayfront
4.0 star property
8.4 out of 10, Very Good, (1483)
"Perfect location. Within an easy walkable distance from Petco Park, Gaslamp area ( excellent for walking and people are friendly. ) great restaurants for pretty much all tastes. Walk down the pier. Walk past the great convention center. There are music halls across the bay. Clean. Relaxing and low key. The Hilton is the perfect starting point. "
The price is ¥25,497
¥36,161 total
includes taxes & fees
May 27 - May 28
Hilton San Diego Bayfront
Courtyard
DoubleTree by Hilton San Diego - Del Mar
4.0 star property
7.2 out of 10, Good, (1032)
"Staff and room was great. Only one elevator which has been out for months. So long lines coming up or down the elevator. "
The price is ¥19,787
¥22,261 total
includes taxes & fees
May 27 - May 28
DoubleTree by Hilton San Diego - Del Mar
Rooftop terrace
Palihotel San Diego
4.0 star property
8.8 out of 10, Excellent, (505)
"Stayed one night. Room was small, but comfortable. "
The price is ¥17,185
¥23,770 total
includes taxes & fees
May 27 - May 28
Palihotel San Diego
Lobby
Gaslamp Plaza Suites
3.5 star property
8.8 out of 10, Excellent, (1001)
"."
The price is ¥17,029
¥18,817 total
includes taxes & fees
May 15 - May 16
Gaslamp Plaza Suites
Lobby
Catamaran Resort and Spa
4.0 star property
7.8 out of 10, Good, (1102)
"Loved the property! Got a first floor bay front room, totally worth it. Beautiful scenery, walks paths and beach access, food options everywhere. The staff were a little on the grumpy side aside from the bellhop and valet workers...we'll definitely stay again. "
The price is ¥38,901
¥50,773 total
includes taxes & fees
May 19 - May 20
Catamaran Resort and Spa
Seasonal outdoor pool, a heated pool
Ocean Villa Inn
2.5 star property
8.2 out of 10, Very Good, (1000)
"Great if you are traveling with pups "
The price is ¥15,326
¥16,936 total
includes taxes & fees
May 15 - May 16
Ocean Villa Inn
Exterior
Loews Coronado Bay Resort
4.0 star property
8.6 out of 10, Excellent, (1054)
"A quiet and peaceful place to relax"
The price is ¥34,214
¥45,126 total
includes taxes & fees
May 27 - May 28
Loews Coronado Bay Resort
Front of property
Pendry San Diego
5.0 star property
9.2 out of 10, Wonderful, (1000)
"Lots of dining options easy walk from the hotel. Pool area was crowded but it was a Saturday and 5th of May! "
The price is ¥45,814
¥59,384 total
includes taxes & fees
May 28 - May 29
Pendry San Diego
Water view
Kona Kai San Diego
4.0 star property
8.4 out of 10, Very Good, (941)
"Clean, great service"
The price is ¥35,777
¥48,250 total
includes taxes & fees
May 28 - May 29
Kona Kai San Diego
Pillowtop beds, in-room safe, desk, blackout drapes
Holiday Inn Express San Diego Downtown, an IHG Hotel
2.5 star property
8.2 out of 10, Very Good, (1000)
"It had a great breakfast option, and a great walking distance to the petco park !!"
The price is ¥22,442
¥25,291 total
includes taxes & fees
May 22 - May 23
Holiday Inn Express San Diego Downtown, an IHG Hotel
Outdoor pool, pool umbrellas, sun loungers
Handlery Hotel
3.5 star property
7.8 out of 10, Good, (1571)
"I was in a quiet area."
The price is ¥20,154
¥22,712 total
includes taxes & fees
May 15 - May 16
Handlery Hotel
Bar (on property)
Sheraton Mission Valley San Diego Hotel
4.0 star property
8.4 out of 10, Very Good, (1099)
"Great overall experience. "
The price is ¥20,950
¥23,610 total
includes taxes & fees
May 27 - May 28
Sheraton Mission Valley San Diego Hotel
Exterior
Springhill Suites San Diego Downtown/Bayfront
3.5 star property
9.2 out of 10, Wonderful, (1000)
"Clean, beautiful property right in the waterfront and close to many San Diego attractions. Parking is expensive in this area but reasonable and easy at this hotel. Centrally located with easy access either walkable or train ride to the marina, little Italy, and gas lamp district. Breakfast was good quality with lots of options. The front desk staff were very nice, and were able to accommodate a late check out which was nice for our overnight stay. "
The price is ¥34,058
¥38,393 total
includes taxes & fees
May 28 - May 29
Springhill Suites San Diego Downtown/Bayfront
Aerial view
Four Points by Sheraton San Diego Downtown Little Italy
3.0 star property
7.0 out of 10, Good, (1001)
"Very comfortable "
The price is ¥24,059
¥27,113 total
includes taxes & fees
May 22 - May 23
Four Points by Sheraton San Diego Downtown Little Italy
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's the best place for a stay in La Mesa?

Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is a favorite property for Expedia customers. This hotel offers an outdoor pool and a fitness center. Reviews from our site also recommend Best Western Plus La Mesa San Diego and Motel 6 La Mesa, CA as top choices for your visit. See all available top hotels, or vacation rentals in La Mesa.

What's the top vacation rental in La Mesa?

Newly renovated waterfront stay with sweeping views, and a private washer/dryer: You might like this vacation home rental near La Mesa. It is near the beach and offers laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in La Mesa.

If I need to cancel my hotel reservation in La Mesa, will I receive a refund?

Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.

Where can I learn more about changing or cancelling my trip to La Mesa?

To find more details about changing or cancelling your trip to La Mesa, head over to our customer service page.

What's the best place to stay on a budget in La Mesa?

Based on our traveler reviews, Motel 6 La Mesa, CA - San Diego is a top choice for a less expensive stay. View all budget hotels in La Mesa.

What's the best place to stay for a family vacation in La Mesa?

Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is a hotel with an outdoor pool and laundry facilities, and it's a top choice on Expedia for families. The Best of San Diego! Room to Enjoy, Relax and Recharge!! is another good option for your stay with the kids. Kids of all ages will also enjoy a visit to Computer Museum of America. Find more child-friendly accommodations in La Mesa.

What's the best place to stay for a romantic getaway to La Mesa?

The Best of San Diego! Room to Enjoy, Relax and Recharge!! is a favorite guesthouse for couples, and features Smart TVs and refrigerators. See all romantic hotels in La Mesa.

What is the top LGBTQ-friendly hotel in La Mesa?

Heritage Inn La Mesa is a top LGBTQ-friendly hotel that features free parking and a sauna. Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is another good option for your trip. See all available hotels listed as LGBTQ-friendly in La Mesa.

What's the best pet-friendly accommodation in La Mesa?

Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is a top hotel for people traveling with their pets, and offers an outdoor pool and free WiFi for its human guests. Two other good options for you and your pet's trip include Motel 6 La Mesa, CA and Motel 6 La Mesa, CA - San Diego. See more pet-friendly hotel accommodations in La Mesa.

Where is the best hotel to stay close to Computer Museum of America?

Lodge of La Mesa (A Quiet Hotel For Adults Only) is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free WiFi. It's located just a short 1 mi (1.6 km) from Computer Museum of America. Other good choices close by include Motel 6 San Diego - La Mesa and Days Inn & Suites by Wyndham San Diego SDSU.

What's the best hotel for a beach vacation in La Mesa?

Lodge of La Mesa (A Quiet Hotel For Adults Only) is a top hotel for a beach vacation, and features free breakfast and free WiFi. Other good choices for your stay near the beach include Days Inn & Suites by Wyndham San Diego SDSU and Heritage Inn La Mesa. Head to Coronado Beach or Mission Bay for some quality time by the water.

What are some accommodations with pools in La Mesa?

Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is a top hotel with a pool, free WiFi, and in-room flat-screen TVs. View all hotels with pools in La Mesa.

What is the best spa hotel in La Mesa?

Best Western Plus La Mesa San Diego is a top spa hotel featuring a fitness center and an outdoor pool. Kick back and relax in the spa tub. See all spa hotels in La Mesa.

What's the top hotel in La Mesa with an on-site water park or a water park nearby?

Quite Peaceful Mountain Retreat is a popular vacation home featuring water park access, an outdoor pool, and in-room kitchens. Another top water park hotel you might want to consider is Top-secret Luxury on Hillside Estate Property, Minutes From Downtown San Diego.

What is the best hotel near San Diego International Airport (SAN)?

Sheraton San Diego Hotel and Marina is a popular 4-star hotel featuring a marina and 3 outdoor pools. It's located a short 0.4 mi (0.6 km) from San Diego Intl. Airport. Other places to stay near the airport are  Hampton Inn & Suites San Diego Airport Liberty Station and Wyndham San Diego Bayside.

What is staying in La Mesa like?

Families will find kid-friendly activities in La Mesa, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its shopping, zoo, and entertainment choices. Around the area, top sights include San Diego Zoo, Mission Bay, and Mission Beach. In La Mesa, there are 148 hotels and other accommodations to choose from. Find out more about La Mesa.

What should I see while I'm in La Mesa?

A couple of favorite places to visit are Mount Helix Park and Computer Museum of America. You'll also find San Diego Zoo and Mission Bay in the area. Check out what more to see and do in Expedia's La Mesa guide.

What's the best way to get around La Mesa?

You can take advantage of metro transit at La Mesa Boulevard Station, Spring St Trolley Station, and 70th St. Trolley Station. If you want to venture out around the area, you may want a rental car in La Mesa for your journey.

What's the seasonal weather like in La Mesa?

The hottest months are usually August and September with an average temp of 72°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for La Mesa is 12 inches.