La Mesa Vacation Rentals

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Check prices for these dates

In two weeks
May 1 - May 3
In two months
Jun 12 - Jun 14
In three months
Jul 10 - Jul 12
In four months
Aug 7 - Aug 9

Our top choices for La Mesa vacation rentals

Dining

Spacious 4BR/2BTH King Bed Ranch Style, Prime Area

Spacious 4BR/2BTH King Bed Ranch Style, Prime Area
La Mesa
The price is ￥22,902
￥54,988 total
includes taxes & fees
Apr 16 - Apr 17
Spacious 4BR/2BTH King Bed Ranch Style, Prime Area
Fridge, microwave, oven, stovetop

SDSU/Downtown <10 Min - GameRoom - Fire Pit - Free Parking - Easy Freeway Access

SDSU/Downtown <10 Min - GameRoom - Fire Pit - Free Parking - Easy Freeway Access
La Mesa
8.8 out of 10, Excellent, (8 reviews)
"Really nice spot. Thanks for letting us stay & enjoy your home! "
United States
Kenneth K.
The price is ￥31,450
￥67,824 total
includes taxes & fees
Apr 21 - Apr 22
SDSU/Downtown <10 Min - GameRoom - Fire Pit - Free Parking - Easy Freeway Access
TV

Mediterranean-inspired 1BR Guesthouse - Full Kitchen, Workspace & Garden

Mediterranean-inspired 1BR Guesthouse - Full Kitchen, Workspace & Garden
Mount Helix
The price is ￥19,855
￥48,446 total
includes taxes & fees
Apr 23 - Apr 24
Mediterranean-inspired 1BR Guesthouse - Full Kitchen, Workspace & Garden
Living area

La Mesa Hillside Escape

La Mesa Hillside Escape
Mount Helix
The price is ￥46,461
￥72,352 total
includes taxes & fees
Apr 26 - Apr 27
La Mesa Hillside Escape
Living area

Large 3BR Oasis with Pool and Games!

Large 3BR Oasis with Pool and Games!
Mount Helix
9.0 out of 10, Wonderful, (2 reviews)
"Yes, Excellent workspace."
United States
Stanley H.
The price is ￥38,360
￥96,972 total
includes taxes & fees
Apr 26 - Apr 27
Large 3BR Oasis with Pool and Games!
Beach

4BR/3Bth King Bed, Big Yard, Prime Area, Ranch

4BR/3Bth King Bed, Big Yard, Prime Area, Ranch
La Mesa
The price is ￥22,053
￥60,314 total
includes taxes & fees
Apr 22 - Apr 23
4BR/3Bth King Bed, Big Yard, Prime Area, Ranch
Interior

4 Bedroom 3 Bathroom Ranch-Style w Gated Yard, Parking

4 Bedroom 3 Bathroom Ranch-Style w Gated Yard, Parking
La Mesa
The price is ￥141,226
￥197,614 total
includes taxes & fees
Apr 16 - Apr 17
4 Bedroom 3 Bathroom Ranch-Style w Gated Yard, Parking
Beach towels

Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (50 reviews)
"Sparkling clean, friendly host and thoughtful layout"
United States
Griff V.
The price is ￥22,015
￥38,744 total
includes taxes & fees
Apr 21 - Apr 22
Adorable 1 bedroom house 8 min from La Jolla!
Rooftop terrace

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (833 reviews)
"Great location"
United States
Ethan
The price is ￥21,467
￥29,493 total
includes taxes & fees
Apr 23 - Apr 24
Sentral Gaslamp Quarter
Terrace/patio

Grand Studio with exclusive resort amenities.

Grand Studio with exclusive resort amenities.
Alpine
10.0 out of 10, Exceptional, (3 reviews)
"This was such a beautiful and peaceful spot — quiet, super adorable, and truly a must-stay when coming into town! The host was incredibly helpful and responsive, which made everything feel effortless. The room itself was quaint, very clean, and had such a cozy charm that made it easy to relax and unwind.I would absolutely stay here again and highly recommend it to anyone looking for a comfortable and delightful place to stay!"
United States
Heather S.
The price is ￥29,385
￥44,792 total
includes taxes & fees
Apr 19 - Apr 20
Grand Studio with exclusive resort amenities.
Smart TV

'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!

'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!
Encanto
8.8 out of 10, Excellent, (32 reviews)
"This was a good central location and convenient to all of San Diego, both in and out of town."
United States
Samuel B.
The price is ￥14,137
￥38,398 total
includes taxes & fees
Apr 28 - Apr 29
'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!
1 bedroom, iron/ironing board, WiFi, bed sheets

Cozy Private Studio in El Cajon

Cozy Private Studio in El Cajon
Mount Helix
8.6 out of 10, Excellent, (20 reviews)
"Everything was great, Sergio was a great host. "
United States
Michael L.
The price is ￥12,151
￥15,328 total
includes taxes & fees
Apr 21 - Apr 22
Cozy Private Studio in El Cajon
Interior

3bd with TV and AC, 2 air mattress, 2ba, 15-20 minute to everything in San Diego

3bd with TV and AC, 2 air mattress, 2ba, 15-20 minute to everything in San Diego
Mount Hope
10.0 out of 10, Exceptional, (23 reviews)
"Yes and very close to all the things we wanted to do, extremely clean and extremely well maintained and extras that were nice like bottles of water"
United States
Brent H.
3bd with TV and AC, 2 air mattress, 2ba, 15-20 minute to everything in San Diego
Smart TV

Casita Sol - Bright Modern Private 10 mins to downtown

Casita Sol - Bright Modern Private 10 mins to downtown
National City
10.0 out of 10, Exceptional, (8 reviews)
"Very cute home, I definitely enjoyed the stay"
United States
Lena _.
The price is ￥18,359
￥31,268 total
includes taxes & fees
Apr 16 - Apr 17
Casita Sol - Bright Modern Private 10 mins to downtown
Fridge, microwave, oven, stovetop

Beautiful Normal Heights Living

Beautiful Normal Heights Living
Mid-City
10.0 out of 10, Exceptional, (82 reviews)
"Great location, nice cozy place, had everything we needed. Would definitely stay again."
United States
Sheila S.
The price is ￥39,710
￥50,492 total
includes taxes & fees
Apr 16 - Apr 17
Beautiful Normal Heights Living
Lobby

Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very Good, (118 reviews)
"Perfect stay!"
United States
Kaylee
The price is ￥17,232
￥19,601 total
includes taxes & fees
Apr 28 - Apr 29
Little Italy Inn - Limited Service Apart Hotel
Terrace/patio

Cozy 2-Bedroom Cottage Near Balboa Park

Cozy 2-Bedroom Cottage Near Balboa Park
Mid-City
9.6 out of 10, Exceptional, (4 reviews)
"This is such a charming cottage in San Diego! Loved our convenient stay and were close to everything that we needed. Thanks!"
United States
Ryne R.
The price is ￥20,490
￥47,726 total
includes taxes & fees
May 3 - May 4
Cozy 2-Bedroom Cottage Near Balboa Park
Outdoor spa tub

Private Resort "La Casita" Spa and Mini Golf Course

Private Resort "La Casita" Spa and Mini Golf Course
ALPINE
10.0 out of 10, Exceptional, (27 reviews)
"Awesome Ola Vibe of Magnificent Lush Property Oasis!!!"
United States
Marcy
The price is ￥27,019
￥49,004 total
includes taxes & fees
Apr 19 - Apr 20
Private Resort "La Casita" Spa and Mini Golf Course
Property grounds

Private Cozy Clean, close to EVERYTHING

Private Cozy Clean, close to EVERYTHING
Mid-City
9.8 out of 10, Exceptional, (61 reviews)
"Great stay! Host was responsive and house was tidy and comfortable. The yard adds an additional living space. "
United States
Helen P.
The price is ￥20,826
￥56,651 total
includes taxes & fees
May 4 - May 5
Private Cozy Clean, close to EVERYTHING
Property grounds

La Casita Guest House, private fenced yard & with heat and AC, pet friendly

La Casita Guest House, private fenced yard & with heat and AC, pet friendly
Mount Helix
9.6 out of 10, Exceptional, (10 reviews)
"Host and amenities were both very nice. "
United States
Juergen S.
The price is ￥17,929
￥48,005 total
includes taxes & fees
Apr 27 - Apr 28
La Casita Guest House, private fenced yard & with heat and AC, pet friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

The Dana on Mission Bay

The Dana on Mission Bay

10/10 Excellent
"My family and I had a great time, friendly staff "
Brandon 4-night trip
Posted 4 hours ago
The Dana on Mission Bay

Find out more about La Mesa

Search for holiday rentals in La Mesa on Expedia! You can easily find your home rentals, villas, holiday apartments in La Mesa using one of the methods below:

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Frequently asked questions

Are there vacation rentals in La Mesa?

Yes, you can find vacation rentals in La Mesa near La Mesa Memorial Fine Arts Center, or you can choose a secluded option if you'd like a relaxing place to stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

What are some of the best vacation rentals that La Mesa has to offer?

Charming 3-bedroom Private Home with Pool & Hot-tub in sunny San Diego: You might want to consider this vacation home rental near La Mesa, which offers a patio, a selection of games, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms and a kitchen with an oven.

How many vacation rentals are there in La Mesa?

With 71 Expedia vacation rentals, you're sure to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

Explore the area and cultural attractions such as Computer Museum of America, or visit a family-friendly sight such as San Diego Zoo. While in the area, you can also visit popular places like Mission Bay and Petco Park.

What are vacation rentals like in La Mesa?

Vacation rentals are privately owned properties you can book for several days or more in La Mesa. Vacation rentals feature amenities such as WiFi and washers and dryers so you'll have everything you need. If you're concerned about a clean environment, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great choice for families.