Find hotels near International Museum of Surgical Science, Chicago from ￥19,144

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Compare 4,213 hotels close to International Museum of Surgical Science with room rates, reviews, and availability. Most hotels are fully refundable.

Private kitchen
The Sono Chicago

The Sono Chicago

3.5 star property
Old Town Chicago, 1.2 km from International Museum of Surgical Science
10.0 out of 10, Exceptional, (484)
"The Sono was welcoming, clean and very comfortable. It was easy to find and provided parking! We would absolutely stay here again and would recommend it to friends. "
United States
Ellen
The price is ￥21,063
￥24,726 total
includes taxes & fees
Dec 9 - Dec 10
The Sono Chicago
Front of property - evening/night
The Peninsula Chicago

The Peninsula Chicago

5.0 star property
Streeterville, 1.6 km from International Museum of Surgical Science
9.8 out of 10, Exceptional, (1001)
"Excellent service throughout the hotel"
United States
Karen
The price is ￥73,782
￥86,611 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Peninsula Chicago
Lobby
The Langham, Chicago

The Langham, Chicago

5.0 star property
River North, 2.4 km from International Museum of Surgical Science
9.8 out of 10, Exceptional, (1001)
"Langham is always a superior stay"
United States
THADDEUS LAMONT
The price is ￥64,190
￥75,351 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Langham, Chicago
Suite, Terrace (Water Tower) | Premium bedding, down comforters, pillowtop beds, minibar
Park Hyatt Chicago

Park Hyatt Chicago

5.0 star property
Magnificent Mile, 1.5 km from International Museum of Surgical Science
9.6 out of 10, Exceptional, (1000)
"Stay was amazing!!! The staff was so friendly, kind, and thoughtful! The rooms were soooo beyond perfect and lovely! And the food at the restaurant was amazing.. especially breakfast! You won’t regret staying here!!! "
United States
Larissa
The price is ￥67,569
￥79,319 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Park Hyatt Chicago
Aerial view
Residence Inn Chicago Downtown Magnificent Mile

Residence Inn Chicago Downtown Magnificent Mile

4.0 star property
River North, 1.8 km from International Museum of Surgical Science
9.6 out of 10, Exceptional, (405)
"Great stay"
United States
John E
The price is ￥19,727
￥23,158 total
includes taxes & fees
Dec 21 - Dec 22
Residence Inn Chicago Downtown Magnificent Mile
Interior
Viceroy Chicago

Viceroy Chicago

4.5 star property
0.9 km from International Museum of Surgical Science
9.4 out of 10, Exceptional, (1145)
"Clean room and lovely staff. Loved the extra holiday vibes! It made our trip to Chicago magical!"
United States
Amanda
The price is ￥26,639
￥35,832 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Viceroy Chicago
Business center
Kasa River North Chicago

Kasa River North Chicago

4.0 star property
Near North Side, 1.6 km from International Museum of Surgical Science
9.6 out of 10, Exceptional, (181)
"Awesome stay "
United States
Sally
The price is ￥34,809
￥55,450 total
includes taxes & fees
Dec 12 - Dec 13
Kasa River North Chicago
Exterior
Sofitel Chicago Magnificent Mile

Sofitel Chicago Magnificent Mile

4.5 star property
1.3 km from International Museum of Surgical Science
9.4 out of 10, Exceptional, (2252)
"The staff, food, and service were great. "
United States
Randy
The price is ￥26,422
￥35,575 total
includes taxes & fees
Dec 11 - Dec 12
Sofitel Chicago Magnificent Mile
Exterior
Waldorf Astoria Chicago

Waldorf Astoria Chicago

5.0 star property
1.2 km from International Museum of Surgical Science
9.4 out of 10, Exceptional, (1003)
"Absolutely fantastic hotel great service, you couldn’t ask for more."
United States
J Michael
The price is ￥61,511
￥72,209 total
includes taxes & fees
Dec 14 - Dec 15
Waldorf Astoria Chicago
Exterior
L7 Chicago by LOTTE

L7 Chicago by LOTTE

4.5 star property
Theatre District, 2.6 km from International Museum of Surgical Science
9.6 out of 10, Exceptional, (3345)
"I loved the location."
United States
Laura
The price is ￥21,893
￥25,700 total
includes taxes & fees
Jan 1 - Jan 2, 2026
L7 Chicago by LOTTE
Reception
Four Seasons Hotel Chicago

Four Seasons Hotel Chicago

5.0 star property
Streeterville, 1.2 km from International Museum of Surgical Science
9.4 out of 10, Exceptional, (1000)
"Amazing hotel"
United States
David
The price is ￥65,239
￥76,584 total
includes taxes & fees
Dec 28 - Dec 29
Four Seasons Hotel Chicago
Restaurant
Thompson Chicago, by Hyatt

Thompson Chicago, by Hyatt

4.5 star property
Gold Coast, 1 km from International Museum of Surgical Science
9.2 out of 10, Wonderful, (1289)
"Nice hotel and awesome location"
United States
Michael
The price is ￥20,992
￥29,225 total
includes taxes & fees
Dec 21 - Dec 22
Thompson Chicago, by Hyatt
Front of property
Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago

4.0 star property
Streeterville, 1.9 km from International Museum of Surgical Science
9.4 out of 10, Exceptional, (2939)
"Excellent stay great location and great rooms"
United States
Joseph
The price is ￥15,378
￥22,429 total
includes taxes & fees
Dec 9 - Dec 10
Hotel Riu Plaza Chicago
Room, 2 Queen Beds, Corner (View) | In-room safe, desk, laptop workspace, blackout drapes
Aloft Chicago Downtown River North

Aloft Chicago Downtown River North

3.5 star property
River North, 2.1 km from International Museum of Surgical Science
9.4 out of 10, Exceptional, (1160)
"Modern vibes, a lot to see, eat and do at walking distance, spotless room and very comfy bed. Very friendly staff. Definitely would stay there again."
United States
Cristina
The price is ￥16,310
￥19,144 total
includes taxes & fees
Dec 21 - Dec 22
Aloft Chicago Downtown River North
Daily full breakfast for a fee
Hotel EMC2, Autograph Collection

Hotel EMC2, Autograph Collection

4.0 star property
Streeterville, 1.9 km from International Museum of Surgical Science
9.4 out of 10, Exceptional, (1002)
"Great stay!"
United States
Bethany
The price is ￥27,959
￥32,822 total
includes taxes & fees
Dec 15 - Dec 16
Hotel EMC2, Autograph Collection
Exterior
Moxy Chicago Downtown

Moxy Chicago Downtown

3.0 star property
River North, 2.1 km from International Museum of Surgical Science
9.4 out of 10, Exceptional, (849)
"Great place to stay"
United States
Mason
The price is ￥17,475
￥20,513 total
includes taxes & fees
Dec 14 - Dec 15
Moxy Chicago Downtown
2 bars/lounges
Hyatt Regency Chicago

Hyatt Regency Chicago

4.0 star property
The Loop, 2.5 km from International Museum of Surgical Science
9.4 out of 10, Exceptional, (3391)
"Everything was amazing, from the staff to the room, amenities simply perfect.!! "
United States
TERESA
The price is ￥21,125
￥29,357 total
includes taxes & fees
Dec 22 - Dec 23
Hyatt Regency Chicago
Lobby
LondonHouse Chicago, Curio Collection by Hilton

LondonHouse Chicago, Curio Collection by Hilton

4.5 star property
The Loop, 2.5 km from International Museum of Surgical Science
9.4 out of 10, Exceptional, (3429)
"Great Hotel!"
United States
Siranush
The price is ￥20,252
￥23,775 total
includes taxes & fees
Jan 4 - Jan 5, 2026
LondonHouse Chicago, Curio Collection by Hilton
Property amenity
citizenM Chicago Downtown

citizenM Chicago Downtown

4.0 star property
Theatre District, 2.6 km from International Museum of Surgical Science
9.4 out of 10, Exceptional, (4094)
"I enjoyed my stay with this hotel and would stay here again"
United States
Kim Leticia Terrelle
The price is ￥16,620
￥19,511 total
includes taxes & fees
Dec 14 - Dec 15
citizenM Chicago Downtown
Property amenity
The Gwen, a Luxury Collection Hotel, Michigan Avenue Chicago

The Gwen, a Luxury Collection Hotel, Michigan Avenue Chicago

4.5 star property
River North, 2.1 km from International Museum of Surgical Science
9.4 out of 10, Exceptional, (1000)
"Perfect stay. Highly recommend "
United States
David
The price is ￥31,555
￥41,602 total
includes taxes & fees
Jan 2 - Jan 3, 2026
The Gwen, a Luxury Collection Hotel, Michigan Avenue Chicago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top International Museum of Surgical Science Hotel Reviews

DoubleTree by Hilton Chicago - Magnificent Mile

DoubleTree by Hilton Chicago - Magnificent Mile

10/10 Excellent
"Friendly staff, clean rooms"
Jill 3-night trip
Posted 8 hours ago
DoubleTree by Hilton Chicago - Magnificent Mile

Hotels near other International Museum of Surgical Science attractions

Exploring exhibits highlighting Chicago's history and development at the Chicago History Museum

Chicago History Museum

Take a stroll through time, with historical artifacts that explore the city’s rich and colorful history.
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North Avenue Beach

Why not spend a carefree afternoon at North Avenue Beach during your travels in Chicago? Experience the entertainment choices and fascinating museums in this vibrant area.
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Frequently asked questions

What's the area like around International Museum of Surgical Science?
International Museum of Surgical Science is located in a vibrant area of Chicago known for its popular theater scene and stunning architecture. If you're looking for a convenient place to stay, check out the 271 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay close to International Museum of Surgical Science?
Hilton Chicago/Magnificent Mile Suites is one of the top choices for your stay based on our traveler data, and this hotel offers a fitness center and valet parking. It's located just a short 0.8 mi (1.2 km) from International Museum of Surgical Science. Other good choices within a short distance include The Whitehall Hotel, BW Premier Collection and The Chicago Hotel Collection Ambassador Gold Coast.
How many hotels are there close to International Museum of Surgical Science?
Expedia has 271 hotels and other accommodations within a mile from International Museum of Surgical Science.
If I need to cancel the hotel reservation for my stay near International Museum of Surgical Science, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view top deals close to International Museum of Surgical Science.
Where can I learn more about changing or cancelling my trip in the area near International Museum of Surgical Science?
To access more information about updating your stay near International Museum of Surgical Science or cancelling it, go to https://www.expedia.com/service/.
What can I see and do near International Museum of Surgical Science?
You might want to spend some time browsing the exhibits at Chicago History Museum, Museum of Contemporary Art Chicago, or Peggy Notebaert Nature Museum. Sights like Chicago Water Tower, Holy Name Cathedral, and Tribune Tower are landmarks to visit in the area. You can watch performances at Second City, Park West, and Broadway Playhouse if you're interested in local theater.
How can I get to International Museum of Surgical Science?
With so many choices for transportation, seeing the area around International Museum of Surgical Science is easy. You can walk to nearby metro stations including State Station, Clark-Lake Station, and Lake Station. If you'd like to explore more of the area, jump aboard a train from Millennium Station, Chicago Van Buren Street Station, or Chicago Union Station.

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