Find Business Hotels in Downtown San Diego, CA

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Downtown San Diego Business Hotels

This weekend
Next weekend

Top Downtown San Diego Business Hotels

Our top choices for Downtown San Diego business-friendly hotels

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2884)
"Great stay overall"
The price is ¥20,676
¥23,766 total
includes taxes & fees
Sep 28 - Sep 29
Legacy Resort Hotel & Spa

Hampton Inn & Suites San Diego Seaworld

2.5 star property
8.8 out of 10, Excellent, (84)
"Enjoyed our stay."
The price is ¥18,080
¥20,783 total
includes taxes & fees
Sep 29 - Sep 30
Hampton Inn & Suites San Diego Seaworld

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1094)
"Very nice clean hotel "
The price is ¥22,747
¥25,066 total
includes taxes & fees
Oct 6 - Oct 7
Ayres Hotel San Diego South - Chula Vista

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
9.0 out of 10, Wonderful, (1135)
"Great stay! "
The price is ¥24,985
¥28,969 total
includes taxes & fees
Sep 25 - Sep 26
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
8.8 out of 10, Excellent, (460)
"Great place to stay! "
The price is ¥17,607
¥20,415 total
includes taxes & fees
Sep 29 - Sep 30
The DEXTRO Little Italy, BW Premier Collection

The Sofia Hotel

3.5 star property
8.4 out of 10, Very Good, (1591)
"I was very happy with my stay."
The Sofia Hotel

Embassy Suites by Hilton San Diego Bay Downtown

4.0 star property
9.0 out of 10, Wonderful, (1439)
"Its a very nice hotel to stay at.. very convenient "
The price is ¥30,800
¥41,070 total
includes taxes & fees
Oct 11 - Oct 12
Embassy Suites by Hilton San Diego Bay Downtown

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very Good, (5990)
"Great stay near the airport."
The price is ¥22,474
¥29,750 total
includes taxes & fees
Sep 28 - Sep 29
Wyndham San Diego Bayside

La Pensione Hotel

3.0 star property
8.6 out of 10, Excellent, (1879)
"Great place to stay they are right in the middle of everything "
La Pensione Hotel

Courtyard by Marriott San Diego Gaslamp/Convention Center

3.0 star property
8.6 out of 10, Excellent, (1004)
"Very clean and great location "
The price is ¥24,963
¥28,944 total
includes taxes & fees
Sep 28 - Sep 29
Courtyard by Marriott San Diego Gaslamp/Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Price trends for hotels in Downtown San Diego

Price trends for hotels in Downtown San Diego

Less expensive
More expensive
Next month
December
June
¥30,146
Month
Price
January
¥33,378
February
¥38,137
March
¥39,228
April
¥42,523
May
¥45,701
June
¥51,834
July
¥48,631
August
¥41,162
September
¥28,974
October
¥30,146
November
¥29,136
December
¥25,133
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Downtown San Diego.

Top Downtown San Diego Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Why book your business-friendly hotel in Downtown San Diego with Expedia?
Expedia is here to help you find a fantastic business-friendly hotel when work takes you out of town. From free parking and WiFi to on-site restaurants and cafés, our stays come with all you'll need to settle that big contract.
How can I find cheap business-friendly hotels in Downtown San Diego?
Expedia can help you easily find cheap business-friendly hotels in Downtown San Diego. Head to our "traveler experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work and rest comfortably, like free WiFi and included breakfast. You can also choose your budget and hotel star rating to keep costs down.