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Find hotels in South San Mateo, San Francisco

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Our top choices for South San Mateo hotels

The Catrina Hotel

The Catrina Hotel
2.5 star property
South San Mateo
8.2 out of 10, Very Good, (943)
"Great stay, would recommend. "
United States
Jesse
The price is ¥13,246
¥15,226 total
includes taxes & fees
Jan 16 - Jan 17, 2026
The Catrina Hotel

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
31.6 km from South San Mateo
9.0 out of 10, Wonderful, (7237)
"Great place to stay!"
United States
Isaiah
The price is ¥15,606
¥24,819 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel Riu Plaza Fisherman's Wharf

Handlery Union Square Hotel

Handlery Union Square Hotel
3.5 star property
29.4 km from South San Mateo
8.8 out of 10, Excellent, (2792)
"Clean hotel, great location, kind staff! "
United States
Felix
The price is ¥19,863
¥23,378 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Handlery Union Square Hotel

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
30.1 km from South San Mateo
8.8 out of 10, Excellent, (2189)
"Great hotel "
United States
Tanya
The price is ¥17,204
¥20,248 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton San Francisco Financial District

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
30 km from South San Mateo
9.0 out of 10, Wonderful, (5039)
"Rooms were great, staff was great, location was great. "
United States
Jonathan
The price is ¥17,536
¥20,640 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Holiday Inn Golden Gateway by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG
3.0 star property
31.6 km from South San Mateo
9.0 out of 10, Wonderful, (2230)
"This was a very nice hotel. Clean, friendly staff, close to everything but also not in the middle of the business of San Francisco. I will definetly stay here again. "
United States
Christina
The price is ¥16,910
¥24,599 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
30 km from South San Mateo
8.8 out of 10, Excellent, (2831)
"Clean room, friendly staff and good location"
United States
Jose Eduardo
The price is ¥15,701
¥18,479 total
includes taxes & fees
Dec 29 - Dec 30
Club Quarters Hotel in San Francisco

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
31.7 km from South San Mateo
9.0 out of 10, Wonderful, (3829)
"Excellent stay and great location! "
United States
CHRISTINE
The price is ¥19,830
¥30,526 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Caza Fisherman's Wharf

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
6.8 km from South San Mateo
8.6 out of 10, Excellent, (2774)
"Breakfast was very good, many options to choose. "
United States
Hourn
The price is ¥16,421
¥18,669 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hilton San Francisco Airport Bayfront

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
9.6 km from South San Mateo
9.0 out of 10, Wonderful, (2242)
"Spotless — not fancy but clean open and comfortable !!! Great airport hotel!!!!"
United States
Michael
The price is ¥16,258
¥18,688 total
includes taxes & fees
Dec 29 - Dec 30
Aloft San Francisco Airport

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
9.6 km from South San Mateo
8.8 out of 10, Excellent, (2018)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
United States
Carole
The price is ¥16,114
¥23,105 total
includes taxes & fees
Dec 30 - Dec 31
The Westin San Francisco Airport

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
29.5 km from South San Mateo
9.4 out of 10, Exceptional, (3112)
"Great hotel, great location, super friendly all staff "
Mexico
Claudia
The price is ¥11,858
¥14,011 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Chancellor Hotel on Union Square

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
31.7 km from South San Mateo
8.6 out of 10, Excellent, (2337)
"This place is wonderful. Would definitely stay again!!"
United States
Jenna
The price is ¥19,667
¥28,676 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Hotel Zephyr San Francisco

King George Hotel

King George Hotel
3.0 star property
29.4 km from South San Mateo
8.6 out of 10, Excellent, (2101)
"Great place!"
United States
Troy
The price is ¥12,466
¥17,023 total
includes taxes & fees
Jan 4 - Jan 5, 2026
King George Hotel

Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco
4.0 star property
31.6 km from South San Mateo
8.6 out of 10, Excellent, (1479)
"Not so special but nice place to stay "
United States
Claire
The price is ¥21,137
¥31,327 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hyatt Centric Fisherman's Wharf San Francisco

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
7.2 km from South San Mateo
8.6 out of 10, Excellent, (1383)
"Great location and staff"
United States
Ernest Dean
The price is ¥18,002
¥20,467 total
includes taxes & fees
Jan 17 - Jan 18, 2026
DoubleTree by Hilton San Francisco Airport

Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto
5.0 star property
24.4 km from South San Mateo
9.4 out of 10, Exceptional, (1213)
"Perfect place to stay and enjoy "
United States
Ali
The price is ¥21,607
¥23,810 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Shashi Hotel Mountain View Palo Alto

Radisson Hotel Sunnyvale – Silicon Valley

Radisson Hotel Sunnyvale – Silicon Valley
3.5 star property
30.6 km from South San Mateo
9.0 out of 10, Wonderful, (1002)
"Clean rooms and amazing staff!"
United States
Grace
The price is ¥17,168
¥19,348 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Radisson Hotel Sunnyvale – Silicon Valley

Maple Tree Inn

Maple Tree Inn
3.0 star property
32.1 km from South San Mateo
9.0 out of 10, Wonderful, (2510)
"Great room and beds, breakfast was amazing "
United States
Donald
The price is ¥14,335
¥16,190 total
includes taxes & fees
Dec 29 - Dec 30
Maple Tree Inn

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf
4.0 star property
31.6 km from South San Mateo
9.2 out of 10, Wonderful, (1637)
"Great location, service, and rooms!"
United States
Joyce
The price is ¥18,178
¥28,050 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel Zoe Fisherman's Wharf
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South San Mateo

Find the best South San Mateo areas and neighborhoods for the activities you enjoy most. Learn more about South San Mateo
Learn more about South San Mateo

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Top South San Mateo Hotel Reviews

Frequently asked questions

What is South San Mateo like?
Guests are sure to enjoy their time checking out all that San Mateo's South San Mateo neighborhood has to offer. Be sure to check out Hillsdale Shopping Center and San Mateo County Event Center as part of your South San Mateo travel plans.
What's the best accommodation in South San Mateo?
Based on Expedia customer reviews, The Catrina Hotel is the highest ranked property in South San Mateo. This hotel offers free parking and free WiFi.
How many hotels are there in the South San Mateo area?
Expedia has 29 hotels and other accommodations in South San Mateo to choose from, making this an ideal home base for exploring the greater San Mateo area.
If I need to cancel my hotel reservation in South San Mateo, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to get the top deals on offer in South San Mateo.
Where can I learn more about changing or cancelling my trip to South San Mateo?
For more information about changing or cancelling your trip to South San Mateo, go to https://www.expedia.com/service/.
What can I see and do in this San Mateo neighborhood?
Spend some time exploring the great outdoors at Sugarloaf Mountain, Paddock Park, and Bay Meadows Park. Hillsdale Shopping Center and San Mateo County Event Center are also a couple of places to visit in the neighborhood. A few places to visit in the area around South San Mateo include Lakeshore Park Beach, The San Mateo Japanese Garden, and Peninsula Museum of Art. While you're out sightseeing, Oceanic Foot Spa and Cinemark Century San Mateo 12 are a couple of additional sights to visit in San Mateo.
How can I get around South San Mateo and the greater San Mateo area?
To venture out of town, take a train from Hillsdale Station.

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