Find hotels in Mission District, San Francisco

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mission District hotels

Union Hotel

Union Hotel
2.0 star property
Mission District
7.0 out of 10, Good, (292 reviews)
"an outstanding stay in a poverty stricken part of town; I had no doubts related to my safety but it is not one of the best parts of the city; and, will stay in the Union Hotel next time I return"
United States
mauricio
The price is ¥8,542
¥9,953 total
includes taxes & fees
Jan 25 - Jan 26
Union Hotel

1906 Mission

1906 Mission
2.0 star property
Mission District
8.0 out of 10, Very Good, (180 reviews)
"Property is fine on a budget but conditions outside make it u safe to walk around "
United States
Damian
The price is ¥14,395
¥16,743 total
includes taxes & fees
Jan 24 - Jan 25
1906 Mission

Parker Guest House San Francisco

Parker Guest House San Francisco
3.5 star property
Mission District
9.6 out of 10, Exceptional, (456 reviews)
"Best place to stay! Beautiful decorations, felt like I was home for Christmas! "
United States
Alison
The price is ¥31,480
¥36,677 total
includes taxes & fees
Jan 26 - Jan 27
Parker Guest House San Francisco

Noe's Nest Bed and Breakfast

Noe's Nest Bed and Breakfast
3.5 star property
Mission District
9.4 out of 10, Exceptional, (123 reviews)
"A very nice and comfortable B&B place to stay..... nestled in the Noe Valley section of San Francisco"
United States
Lester
The price is ¥37,175
¥43,238 total
includes taxes & fees
Jan 26 - Jan 27
Noe's Nest Bed and Breakfast

Hotel Sunrise

Hotel Sunrise
2.0 star property
Mission District
6.8 out of 10, (640 reviews)
"Sextant coffee good place"
United States
Audrey
The price is ¥10,770
¥12,527 total
includes taxes & fees
Jan 23 - Jan 24
Hotel Sunrise

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 5.3 km from Mission District
9.0 out of 10, Wonderful, (7,287 reviews)
"Nice location, GREAT breakfast, friendly staff, comfortable room"
United States
Gary
The price is ¥17,001
¥26,527 total
includes taxes & fees
Feb 10 - Feb 11
Hotel Riu Plaza Fisherman's Wharf

YOTEL San Francisco

YOTEL San Francisco
3.0 star property
2.4 km from Mission District
8.2 out of 10, Very Good, (1,001 reviews)
"Great place to stay in the city. Rooms are small but modern and clean staff is courteous and friendly. There is 24 hour security its a great place and is affordable."
United States
Sherretha
The price is ¥10,901
¥19,346 total
includes taxes & fees
Jan 24 - Jan 25
YOTEL San Francisco

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
Financial District, 4.1 km from Mission District
8.8 out of 10, Excellent, (2,317 reviews)
"We loved our stay! "
United States
Christine
The price is ¥16,620
¥19,561 total
includes taxes & fees
Jan 25 - Jan 26
Hilton San Francisco Financial District

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 5.2 km from Mission District
9.2 out of 10, Wonderful, (1,677 reviews)
"The hotel was very nice and located near many attractions. "
United States
Sergio
The price is ¥15,786
¥25,277 total
includes taxes & fees
Feb 9 - Feb 10
Hotel Zoe Fisherman's Wharf

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 5.3 km from Mission District
9.0 out of 10, Wonderful, (3,819 reviews)
"Nice place to stay"
United States
Harold Franklin
The price is ¥19,739
¥30,865 total
includes taxes & fees
Jan 23 - Jan 24
Hotel Caza Fisherman's Wharf

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
Fisherman's Wharf, 5.4 km from Mission District
8.6 out of 10, Excellent, (2,383 reviews)
"Great place to stay with kids. Walkable to most everything and seemed very safe "
United States
Amy
The price is ¥19,799
¥29,818 total
includes taxes & fees
Jan 28 - Jan 29
Hotel Zephyr San Francisco

The Dylan at SFO

The Dylan at SFO
3.0 star property
18.2 km from Mission District
9.2 out of 10, Wonderful, (1,833 reviews)
"great hotel, well designed, comfortable beds, easy access to the bart and aiport"
United States
Alan
The price is ¥17,275
¥20,574 total
includes taxes & fees
Jan 23 - Jan 24
The Dylan at SFO

Hotel Del Sol

Hotel Del Sol
3.0 star property
Cow Hollow, 4.7 km from Mission District
8.6 out of 10, Excellent, (1,003 reviews)
"Absolutely strong wi fi - excellent staff - "
United States
CAMILO
The price is ¥16,433
¥24,213 total
includes taxes & fees
Jan 27 - Jan 28
Hotel Del Sol

Handlery Union Square Hotel

Handlery Union Square Hotel
3.5 star property
Union Square, 3.2 km from Mission District
8.8 out of 10, Excellent, (2,834 reviews)
"Great location, room was clean and staff was helpful."
United States
Laura
The price is ¥20,069
¥23,620 total
includes taxes & fees
Jan 25 - Jan 26
Handlery Union Square Hotel

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
19.9 km from Mission District
8.6 out of 10, Excellent, (2,880 reviews)
"The room and breakfast was perfect "
United States
Daniel
The price is ¥16,733
¥19,025 total
includes taxes & fees
Jan 31 - Feb 1
Hilton San Francisco Airport Bayfront

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
3.3 km from Mission District
9.4 out of 10, Exceptional, (3,157 reviews)
"Everything and everyone made the stay amazing"
United States
Angela
The price is ¥15,518
¥18,313 total
includes taxes & fees
Jan 25 - Jan 26
Chancellor Hotel on Union Square

King George Hotel

King George Hotel
3.0 star property
Union Square, 3.1 km from Mission District
8.6 out of 10, Excellent, (2,094 reviews)
"The staff were all friendly and courteous, the room and bathroom were very clean, the beds were comfortable and a very good location."
United States
Jamie
The price is ¥14,095
¥18,959 total
includes taxes & fees
Jan 23 - Jan 24
King George Hotel

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
Financial District, 4.2 km from Mission District
9.0 out of 10, Wonderful, (2,912 reviews)
"nice location"
United Kingdom
Natthaya
The price is ¥16,863
¥19,847 total
includes taxes & fees
Feb 16 - Feb 17
Club Quarters Hotel in San Francisco

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
19.6 km from Mission District
8.6 out of 10, Excellent, (1,437 reviews)
"Very nice hotel"
United States
Mary Ann
The price is ¥15,177
¥17,256 total
includes taxes & fees
Jan 30 - Jan 31
DoubleTree by Hilton San Francisco Airport

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
Nob Hill, 3.4 km from Mission District
9.0 out of 10, Wonderful, (5,158 reviews)
"Great stay!"
United States
Carlos Emiro
The price is ¥18,858
¥22,195 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Golden Gateway by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission District

Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Learn more about Mission District

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Top Mission District Hotel Reviews

Frequently asked questions

What is Mission District like?
Mission District is a neighborhood that travelers like for its bars. Are you looking for Mission District travel tips? Be sure to check out SF Armory and SOMA Pilipinas while you're in the neighborhood.
Where is the best place to stay in Mission District?
Based on Expedia customer reviews, Parker Guest House San Francisco is the highest ranked property in Mission District. This B&B offers free breakfast and free WiFi. Other top choices in the neighborhood include Noe's Nest Bed and Breakfast and 1906 Mission.
How many hotels should I expect to find in the Mission District area?
Expedia has 70 hotels and other accommodations in Mission District to choose from, making this an ideal home base for exploring the greater San Francisco area.
If I need to cancel my hotel reservation in Mission District, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get top deals in Mission District.
Where can I learn more about changing or cancelling my trip to Mission District?
To access more information about rescheduling or cancelling your trip to Mission District, click here.
What are the top things to see and do in Mission District?
Mission District's sights and attractions like Marsh Theater, Victoria Theatre, and Creativity Explored offer insight into the local culture. SF Armory and SOMA Pilipinas are also a couple of places to visit in the neighborhood. Chase Center and Oracle Park are some favorite places to visit in the area around Mission District. While you're out sightseeing in San Francisco, be sure to visit other sights like Paxton Gate or Incline Gallery.
How can I get around Mission District and the greater San Francisco area?
For a quick way to explore the city, catch a ride on metro transit at 16th Street Mission Station, 24th Street Mission Station, or Right Of Way/20th St Stop.

Explore a world of travel with Expedia