Mission District Vacations from ￥149,832

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ￥45,448 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Mission District Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Castle Inn

Castle Inn

2 out of 5
Downtown San Francisco
Price was ￥179,440, price is now ￥149,832 per person
￥149,832
per person
May 16 - May 20
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to San Francisco (SFO)
9.2/10 Wonderful! (1,001 reviews)
Place was clean, staff was nice.

Reviewed on Feb 14, 2026

The Grove Inn

The Grove Inn

3 out of 5
Western Addition
Price was ￥274,966, price is now ￥188,432 per person
￥188,432
per person
May 16 - May 20
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to San Francisco (SFO)
9.2/10 Wonderful! (670 reviews)
We had a deluxe king room. The room was small and basic, but sparkly clean and had a very comfortable bed. We really liked the location. It was very central to everything we wanted to do.

Reviewed on Feb 12, 2026

Marriott San Francisco Fisherman's Wharf

Marriott San Francisco Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Price was ￥202,400, price is now ￥163,318 per person
￥163,318
per person
May 16 - May 20
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to San Francisco (SFO)
8.8/10 Excellent! (1,000 reviews)
Staff was excellent

Reviewed on Feb 21, 2026

White Swan Inn

White Swan Inn

3.5 out of 5
Union Square
Price was ￥243,014, price is now ￥198,450 per person
￥198,450
per person
May 16 - May 20
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to San Francisco (SFO)
9.2/10 Wonderful! (1,000 reviews)
Charming hotel! Very nice continental breakfast. Very clean property. Fireplaces are nice for a quick warm-up.

Reviewed on Feb 24, 2026

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

4 out of 5
Fisherman's Wharf
Price was ￥196,152, price is now ￥160,306 per person
￥160,306
per person
May 16 - May 20
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to San Francisco (SFO)
8.6/10 Excellent! (2,277 reviews)
Friendly and helpful Management and Staff.

Reviewed on Feb 26, 2026

Where to stay in Mission District

Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Vibrant activity in Union Square, San Francisco with palm trees and bustling city life

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Mission District Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundable
The price is ￥19,741 per night from Mar 1 to Mar 2
￥19,741
￥23,234 total
Mar 1 - Mar 2
includes taxes & fees
9/10 Wonderful! (5,342 reviews)
Helpful staff, amenities, and overall great vibes

Reviewed on Feb 27, 2026

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is ￥22,073 per night from Mar 3 to Mar 4
￥22,073
￥32,407 total
Mar 3 - Mar 4
includes taxes & fees
9/10 Wonderful! (7,323 reviews)
Save environment, save water, the water flow in sink made me exhausted, this is waste time instead of waste water.

Reviewed on Feb 28, 2026

Hotel Riu Plaza Fisherman's Wharf
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
The price is ￥24,433 per night from Mar 1 to Mar 2
￥24,433
￥28,756 total
Mar 1 - Mar 2
includes taxes & fees
8.8/10 Excellent! (2,876 reviews)
Room was nice and clean, the staff are amazing, especially to Shiley she was the best 👍

Reviewed on Feb 27, 2026

Handlery Union Square Hotel
See all 4,947 properties in Mission District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission District vacation package cost?
Our Mission District packages, which begin at just ￥149,832, are an awesome way to save big. Pick your favorite flights, hotels and rental cars to create a customized escape.
How do I get a cheap travel package to Mission District?
By bundling. Flights, rental cars and hotels — combine whatever you need into a Mission District vacation package to save a pile of cash. Score even more deals when you add extras such as sightseeing tours to your booking. But that's not the only impressive part. You have the freedom to customize your vacation your own way. We offer more than 550 partner airlines and 1,000,000 hotels worldwide, so that everyone has a chance to travel and live out those vacation dreams.
Where should I stay in Mission District?
A visit to Mission District isn't complete until you've seen Pier 39 and Alcatraz Island. Book a room close by for quick access to these popular attractions.
What are the top hotels in Mission District?
If it's your first time staying in Mission District, lock in a room at 1906 Mission or Charming And Cozy Dolores Park Condo By Redawning. Both will make you feel at home and are favorites among lots of travelers.
How far in advance should I book my Mission District vacation?
To bag rock-bottom prices, book ASAP. Airlines usually start selling tickets, along with some of the lowest fares, around 12 months ahead of time. Hotels, car rental and experiences should also be booked early so you can have the pick of the bunch. If you've decided on a last-minute getaway in Mission District, there are always lots of great deals to be had on Expedia. Book your escape today!
What does an Expedia Mission District travel package include?
It all boils down to what sort of getaway you want to have. Mission District vacation deals can include car rentals, hotels and flights. You can mix and match to create the travel package that fits your needs. You can also add on activities and experiences after you've booked to pick up even bigger discounts.
What should I know before booking a Mission District travel package?
Booking all the parts of your escape together is one of the best ways to save. Bundle your car rentals, airfares and hotels into a convenient package. But you're not restricted to hotels. Expedia has all types of properties, including vacation rentals like beachfront villas and serviced residences. You've got loads of choices!
Can I choose my airline with a Mission District Expedia vacation package?
With a vacation package, you're always in charge. Whether you want to fly to Mission District in first class or coach, simply select from the available airline options. Expedia has access to more than 550 airline partners around the world.
If I'm not able to travel, can I cancel my Mission District vacation package?
You sure can, and we're here to help. You may be able to cancel or change your Mission District vacation package for free if you booked in the last 24 hours. But you may incur a fee from your airline, hotel or car rental company if you booked more than 24 hours ago. If your travel plans unexpectedly change, visit our Customer Service Portal for more information.

Discover the most popular places to visit in Mission District

Mission Dolores Park showing picnicing and a park as well as a small group of people

Mission Dolores Park

Mission Dolores Park is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Discover the beautiful sunsets and top-notch restaurants in this vibrant area.

Mission Dolores Park
Balmy Alley which includes outdoor art

Balmy Alley

Balmy Alley is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Experience the fascinating museums and acclaimed art scene in this vibrant area.

Balmy Alley
Mission San Francisco de Asís was founded 29 June 1776 by Padre Francisco Palóu and Padre Pedro Benito Cambón. The mission is named for Saint Francis of Assisi. The current site was picked in 1782 because of the harsh conditions at the original mission. It is considered to be the oldest intact building in San Francisco. The Mission is located in the San Francisco Mission District at the corner of 16th and Dolores Streets. #Details #golden #troveontuesday #Trovember

Mission San Francisco de Asís

Learn about the local history of San Francisco when you spend time at Mission San Francisco de Asís. Visit the shops and notable monuments in this vibrant area.

Mission San Francisco de Asís

Things to do

Alcatraz Island Prison Tour Package

Official Alcatraz Island Prison Tour with Free App Audio Packages

￥11,918
per adult
100% of travellers recommend
Official Alcatraz Island Prison Tour with Free App Audio Packages
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

￥7,584
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise

San Francisco City Lights Cruise (2-hours)

￥8,977
per adult
94% of travellers recommend
San Francisco City Lights Cruise (2-hours)
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.