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Find Luxury Hotels in Mission Bay, CA

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Check availability on Mission Bay Luxury Hotels

Tonight
Dec 28 - Dec 29
Tomorrow
Dec 29 - Dec 30
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

Our top choices for Mission Bay luxury hotels

Exterior
LUMA Hotel San Francisco

LUMA Hotel San Francisco

LUMA Hotel San Francisco
4.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (2398)
"Staff were so nice, the rooms were clean will definitely come back "
United States
Karla
The price is ￥30,531
￥35,934 total
includes taxes & fees
Jan 4 - Jan 5, 2026
LUMA Hotel San Francisco
Lobby sitting area
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
Fisherman's Wharf
9.0 out of 10, Wonderful, (7250)
"Great place to stay!"
United States
Isaiah
The price is ￥15,606
￥24,819 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel Riu Plaza Fisherman's Wharf
Front of property - evening/night
Hilton San Francisco Financial District

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
Downtown San Francisco
8.8 out of 10, Excellent, (2201)
"Great hotel "
United States
Tanya
The price is ￥17,204
￥20,248 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton San Francisco Financial District
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
Fisherman's Wharf
9.0 out of 10, Wonderful, (3836)
"Excellent stay and great location! "
United States
CHRISTINE
The price is ￥19,830
￥30,526 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Caza Fisherman's Wharf
Exterior
Lafayette Park Hotel & Spa

Lafayette Park Hotel & Spa

Lafayette Park Hotel & Spa
4.0 star property
Lafayette
9.4 out of 10, Exceptional, (1002)
"Very clean room, great staff and service, and the meal at the Park Bistro was exceptional!"
United States
Ahsan
The price is ￥34,469
￥37,811 total
includes taxes & fees
Jan 22 - Jan 23, 2026
Lafayette Park Hotel & Spa
Interior
Hotel Shattuck Plaza

Hotel Shattuck Plaza

Hotel Shattuck Plaza
4.0 star property
Downtown Berkeley
8.8 out of 10, Excellent, (1095)
"Wonderful, will stay here again."
United States
Jennifer
Hotel Shattuck Plaza
Exterior
Graduate by Hilton Berkeley

Graduate by Hilton Berkeley

Graduate by Hilton Berkeley
4.0 star property
Telegraph District
8.4 out of 10, Very Good, (1003)
"Great location and service, and a very comfortable stay"
United States
Carina
The price is ￥20,414
￥28,304 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Graduate by Hilton Berkeley
3 outdoor pools, open 6:00 AM to 9:00 PM, pool umbrellas, sun loungers
Claremont Resort & Club

Claremont Resort & Club

Claremont Resort & Club
5.0 star property
Claremont Hills
8.8 out of 10, Excellent, (1007)
"Great hotel"
United States
Peter
The price is ￥34,273
￥48,749 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Claremont Resort & Club
Exterior
DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina
4.0 star property
Berkeley Marina
8.2 out of 10, Very Good, (4039)
"Clean rooms, great breakfast options & friendly staff"
United States
Beth
The price is ￥18,600
￥21,426 total
includes taxes & fees
Jan 18 - Jan 19, 2026
DoubleTree by Hilton Hotel Berkeley Marina
Exterior
Residence Inn by Marriott Berkeley

Residence Inn by Marriott Berkeley

Residence Inn by Marriott Berkeley
4.0 star property
Downtown Berkeley
9.2 out of 10, Wonderful, (538)
"Staff were excellent. Room was spacious. Good breakfast and really nice bar upstairs. "
United States
Rona
The price is ￥25,677
￥29,579 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Residence Inn by Marriott Berkeley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mission Bay Hotel Reviews

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

10/10 Excellent
" Everything looked great"
Alma Isayana 4-night trip
Posted 15 hours ago
Holiday Inn Golden Gateway by IHG

Frequently asked questions

Are you looking for a luxury hotel for your Mission Bay vacation?
Use Expedia to arrange your flight to Oakland Intl. Airport (OAK) airport or San Francisco Intl. Airport (SFO) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a trip, so we make it easy to find what you'd like to make your stay special. If you want a posh hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Mission Bay offers. Mission Bay has some interesting things to see and do including Chase Center and Lefty O'Doul Bridge, so you might want to take in the local sights during your visit.
What's there to see and do in Mission Bay?
When you're in Mission Bay, enjoy exploring the sights and attractions here including Chase Center, Lefty O'Doul Bridge, and Lucky Strike San Francisco. If you have some spare time during your trip, you might want to check out Oracle Park and Pier 39.
How can I get around Mission Bay?
It's easier to get around town in style when you know your options. You can walk to nearby metro stations including UCSF/Chase Center Stop, Mission Rock Station, and UCSF Mission Bay Stop.

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