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Our top choices for Midtown hotels

Element St. Louis Midtown

Element St. Louis Midtown
3.0 star property
Midtown
9.0 out of 10, Wonderful, (668 reviews)
"Staff was amazing and hotel was super clean. Great locations with easy access. Valet was fast and took great care of us. "
United States
Kyle
The price is ¥20,624
¥24,116 total
includes taxes & fees
Mar 2 - Mar 3
Element St. Louis Midtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.8 out of 10, Good, (1,002 reviews)
"All good"
United States
Christopher-Joi
The price is ¥16,805
¥19,985 total
includes taxes & fees
Feb 22 - Feb 23
Residence Inn by Marriott St Louis Downtown

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
27.6 km from Midtown
8.6 out of 10, Excellent, (666 reviews)
"Room was great,staff friendly! All together a great stay."
United States
Zachary
The price is ¥13,902
¥15,984 total
includes taxes & fees
Feb 15 - Feb 16
Country Hearth Inn & Suites Edwardsville St. Louis

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
16 km from Midtown
9.2 out of 10, Wonderful, (1,000 reviews)
"Great hotel"
United States
Leon
The price is ¥17,737
¥21,777 total
includes taxes & fees
Mar 1 - Mar 2
Hyatt Select St. Louis Airport

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
29.4 km from Midtown
9.4 out of 10, Exceptional, (734 reviews)
"Super breakfast, kind and efficient staff, clean"
United States
Sarah
The price is ¥17,110
¥18,988 total
includes taxes & fees
Mar 1 - Mar 2
Holiday Inn Express Troy by IHG

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
29.2 km from Midtown
8.0 out of 10, Very Good, (1,001 reviews)
"I enjoy staying here."
United States
Kelley
The price is ¥9,739
¥10,808 total
includes taxes & fees
Feb 20 - Feb 21
Super 8 by Wyndham Troy IL/St. Louis Area

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
24.2 km from Midtown
8.4 out of 10, Very Good, (823 reviews)
"Great staff, breakfast was excellent and rooms were clean"
United States
Carlos
The price is ¥14,935
¥17,172 total
includes taxes & fees
Feb 22 - Feb 23
Comfort Inn Edwardsville - St. Louis

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
21 km from Midtown
8.6 out of 10, Excellent, (1,761 reviews)
"Clean rooms, enough set of towels, bathroom was clean & good hot water, staff was very nice, I would recommend this location & hotel"
United States
Jaziel
The price is ¥8,065
¥9,858 total
includes taxes & fees
Mar 1 - Mar 2
Motel 6 Hazelwood, MO

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
19.7 km from Midtown
8.0 out of 10, Very Good, (612 reviews)
"Clean room, friendly staff, good breakfast "
United States
Saulius
The price is ¥9,212
¥10,430 total
includes taxes & fees
Feb 15 - Feb 16
Red Lion Inn & Suites Pontoon Beach

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
17.2 km from Midtown
9.2 out of 10, Wonderful, (1,523 reviews)
"Great stay "
United States
Sandra
The price is ¥14,788
¥17,411 total
includes taxes & fees
Feb 19 - Feb 20
Wingate by Wyndham St. Louis Airport

Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
2.5 star property
Dogtown, 4.8 km from Midtown
9.4 out of 10, Exceptional, (1,000 reviews)
"Was perfect for a family stay. Nice rooms, quiet, close to Zoo and Science center."
United States
Joseph
The price is ¥18,665
¥22,012 total
includes taxes & fees
Feb 19 - Feb 20
Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport
2.5 star property
16.3 km from Midtown
8.8 out of 10, Excellent, (122 reviews)
"Great stay!"
United States
Allyn
The price is ¥18,164
¥21,676 total
includes taxes & fees
Feb 22 - Feb 23
Hampton Inn By Hilton St Louis Airport

Comfort Inn & Suites Saint Louis Lafayette Square

Comfort Inn & Suites Saint Louis Lafayette Square
2.5 star property
The Gate, 2 km from Midtown
8.0 out of 10, Very Good, (283 reviews)
"Very clean and quiet"
United States
Adrienne
The price is ¥15,005
¥17,545 total
includes taxes & fees
Feb 22 - Feb 23
Comfort Inn & Suites Saint Louis Lafayette Square

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
23.2 km from Midtown
8.0 out of 10, Very Good, (1,096 reviews)
"Great room, great people, great breakfast "
United States
Jaiden
The price is ¥13,635
¥15,748 total
includes taxes & fees
Feb 15 - Feb 16
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
27.8 km from Midtown
9.2 out of 10, Wonderful, (846 reviews)
"Very good staff and great breakfast service."
United States
Denise
The price is ¥20,929
¥24,065 total
includes taxes & fees
Feb 22 - Feb 23
Holiday Inn Express & Suites Edwardsville by IHG

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
11.9 km from Midtown
9.0 out of 10, Wonderful, (1,482 reviews)
"Clean and comfy great food "
United States
Theresa A
The price is ¥13,346
¥17,751 total
includes taxes & fees
Feb 19 - Feb 20
River City Casino & Hotel

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 3.4 km from Midtown
9.4 out of 10, Exceptional, (3,310 reviews)
"Nice staff, clean rooms, dinner and breakfast for quests. "
United States
Brad
The price is ¥21,997
¥25,721 total
includes taxes & fees
Feb 17 - Feb 18
Drury Plaza Hotel St. Louis at the Arch

Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach
3.0 star property
18.3 km from Midtown
8.6 out of 10, Excellent, (823 reviews)
"Everything was very nice"
United States
Todd
The price is ¥12,220
¥13,562 total
includes taxes & fees
Feb 15 - Feb 16
Best Western Plus Pontoon Beach

Best Western St. Louis Inn

Best Western St. Louis Inn
2.5 star property
22.7 km from Midtown
8.0 out of 10, Very Good, (1,001 reviews)
"Great little hotel "
United States
Marisa
The price is ¥10,388
¥11,945 total
includes taxes & fees
Feb 22 - Feb 23
Best Western St. Louis Inn

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
23.3 km from Midtown
8.0 out of 10, Very Good, (1,137 reviews)
"Clean place in friendly service"
United States
David
The price is ¥12,076
¥13,947 total
includes taxes & fees
Feb 15 - Feb 16
Wingate by Wyndham St. Louis/Fenton Route 66
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Soulard

You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Top Midtown Hotel Reviews

Frequently asked questions

What is Midtown like?
Travelers are sure to enjoy a stay in St. Louis's Midtown neighborhood. Be sure to check out Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on Expedia customer reviews, Element St. Louis Midtown is the highest ranked property in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool. Another top choice in the area is Residence Inn by Marriott St Louis Downtown.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 35 Midtown hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best options available in Midtown.
Where can I learn more about changing or cancelling my trip to Midtown?
To access more information about picking new dates or cancelling your trip to Midtown, go to https://www.expedia.com/service/.
What are the top things to see and do in Midtown?
Explore Midtown's landmarks like Washington Avenue Historic District, Scott Joplin House State Historic Site, and Samuel Cupples House and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighborhood. Favorite places to visit in the surrounding area include St. Louis Union Station, Busch Stadium, and Gateway Arch. While you're out sightseeing, .ZACK Theater and The MOTO Museum are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.

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