Lodging Image

Find hotels in Midtown, St. Louis

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Midtown hotels

1. Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown
3.0 star property
Midtown
8.8 out of 10, Excellent, (846 reviews)
"Would stay again!"
United States
Julie
The price is ¥20,893
¥24,429 total
includes taxes & fees
Oct 25 - Oct 26
Element by Marriott St. Louis Midtown

2. Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.6 out of 10, Good, (1,000 reviews)
"Suite with two rooms and a pullout bed was very convenient for a family of 5."
United States
Patrick
The price is ¥17,411
¥20,706 total
includes taxes & fees
Nov 1 - Nov 2
Residence Inn by Marriott St Louis Downtown

3. Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
3.0 star property
Downtown West, 1.3 km from Midtown
9.2 out of 10, Wonderful, (1,004 reviews)
"Nice stay!"
United States
Brooke
The price is ¥18,376
¥21,907 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn & Suites by Marriott St. Louis Downtown

4. Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station
3.0 star property
Downtown West, 1.2 km from Midtown
8.8 out of 10, Excellent, (2,259 reviews)
"Great location and loved the happy hour drinks and snacks"
United States
Larry
The price is ¥16,460
¥19,246 total
includes taxes & fees
Oct 25 - Oct 26
Pear Tree Inn St. Louis Near Union Station

5. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West, 2.1 km from Midtown
9.0 out of 10, Wonderful, (2,129 reviews)
"Wonderful Stay!"
United States
A.R.
The price is ¥22,737
¥27,377 total
includes taxes & fees
Nov 15 - Nov 16
21C Museum Hotel St Louis

6. Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station
3.0 star property
Downtown West, 1.5 km from Midtown
9.4 out of 10, Exceptional, (1,604 reviews)
"Amazing food and friendly staff"
United States
Andrea
The price is ¥17,884
¥21,269 total
includes taxes & fees
Nov 1 - Nov 2
Drury Plaza Hotel St. Louis Union Station

7. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West, 1.7 km from Midtown
8.8 out of 10, Excellent, (1,003 reviews)
"Beautiful property. We enjoyed the food & the light shows in the Grand Hall. We also enjoyed riding the St. Louis Wheel & visiting the Aquarium. The “Whispering Wall” caught our attention as well."
United States
Donna
The price is ¥25,828
¥30,716 total
includes taxes & fees
Oct 31 - Nov 1
St. Louis Union Station Hotel, Curio Collection by Hilton

8. Comfort Inn & Suites Saint Louis Lafayette Square

Comfort Inn & Suites Saint Louis Lafayette Square
2.5 star property
The Gate, 2 km from Midtown
8.2 out of 10, Very good, (422 reviews)
"Great breakfeast and the room was clean. Also lot of room to park!"
United States
greg
The price is ¥18,120
¥21,187 total
includes taxes & fees
Oct 28 - Oct 29
Comfort Inn & Suites Saint Louis Lafayette Square

9. Aloft by Marriott St Louis Central West End

Aloft by Marriott St Louis Central West End
3.0 star property
Central West End, 2.2 km from Midtown
8.6 out of 10, Excellent, (1,002 reviews)
"Very nice staff and helped us with all our needs and was close to the event we were going to and loved the pool table and pool they had there"
United States
Brittany
The price is ¥18,028
¥21,079 total
includes taxes & fees
Oct 25 - Oct 26
Aloft by Marriott St Louis Central West End

10. Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 2.9 km from Midtown
9.0 out of 10, Wonderful, (1,009 reviews)
"One of the best hotels I have stayed in . Clean spacious and very comfortable, Would defiantly stay here again. Super close to convention center"
United States
Jed
The price is ¥16,683
¥19,841 total
includes taxes & fees
Nov 15 - Nov 16
Courtyard by Marriott St. Louis Downtown/Convention Center

11. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 3.4 km from Midtown
8.6 out of 10, Excellent, (4,361 reviews)
"Great place to stay"
United States
David
The price is ¥21,256
¥25,068 total
includes taxes & fees
Oct 30 - Oct 31
Hyatt Regency St. Louis at The Arch

12. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 3 km from Midtown
8.6 out of 10, Excellent, (1,002 reviews)
"Very clean room staff was awesome. Recommend."
United States
MARY
The price is ¥24,609
¥28,777 total
includes taxes & fees
Oct 25 - Oct 26
Home2 Suites by Hilton St. Louis/Forest Park

13. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 3 km from Midtown
9.4 out of 10, Exceptional, (1,351 reviews)
"Great place to stay."
United States
brandon
The price is ¥22,001
¥26,166 total
includes taxes & fees
Nov 15 - Nov 16
Live by Loews - St.Louis

14. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 3.1 km from Midtown
9.0 out of 10, Wonderful, (1,362 reviews)
"Big rooms, good location, great breakfast, friendly staff."
United Kingdom
Luke
The price is ¥18,701
¥22,242 total
includes taxes & fees
Oct 27 - Oct 28
Embassy Suites by Hilton St. Louis Downtown

15. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 3.4 km from Midtown
9.6 out of 10, Exceptional, (3,809 reviews)
"Clean,friendly staff. Would definitely stay there again"
United States
Theresa
The price is ¥21,366
¥24,983 total
includes taxes & fees
Oct 25 - Oct 26
Drury Plaza Hotel St. Louis at the Arch

16. AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End, 3.4 km from Midtown
9.0 out of 10, Wonderful, (858 reviews)
"Everything at this hotel was perfect. From the valet to the front desk to the breakfast were so friendly and nice. We will definitely stay here again. The location is also perfect"
United States
Janice
The price is ¥22,737
¥26,814 total
includes taxes & fees
Oct 25 - Oct 26
AC Hotel St. Louis Central West End

17. Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West, 2.5 km from Midtown
7.8 out of 10, Good, (1,010 reviews)
"Its a nice hotel with good breakfast"
United States
Arthur
The price is ¥14,665
¥17,146 total
includes taxes & fees
Nov 1 - Nov 2
Tru By Hilton St. Louis Downtown

18. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
3.5 star property
Downtown St. Louis, 3.5 km from Midtown
8.8 out of 10, Excellent, (1,447 reviews)
"Would stay here again with my family"
United States
Andrew
The price is ¥17,392
¥20,337 total
includes taxes & fees
Oct 27 - Oct 28
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

19. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End, 3.6 km from Midtown
9.2 out of 10, Wonderful, (1,010 reviews)
"The Sonesta is a lovely hotel with a beautiful pool. Our stay was a relaxing getaway and pleasant in every way."
United States
Kristina
The price is ¥25,483
¥34,717 total
includes taxes & fees
Nov 15 - Nov 16
The Royal Sonesta Chase Park Plaza St. Louis

20. Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 3.4 km from Midtown
8.8 out of 10, Excellent, (1,152 reviews)
"Enjoyed our stay"
United States
Mary
The price is ¥17,355
¥20,293 total
includes taxes & fees
Nov 15 - Nov 16
Hilton Pennywell St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Midtown

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
An outdoor patio area with seating, planters, and a grill.
Element by Marriott St. Louis Midtown
3.0 star property
8.8
Excellent
846 reviews
View
An outdoor patio area with seating, a fire pit, and a grill.
Residence Inn by Marriott St Louis Downtown
3.0 star property
7.6
Good
1,000 reviews
View
A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.
Fairfield Inn & Suites by Marriott St. Louis Downtown
3.0 star property
9.2
Wonderful
1,004 reviews
View
An indoor pool area with a hot tub, seating, and a stone wall.
Drury Plaza Hotel St. Louis Union Station
3.0 star property
9.4
Exceptional
1,604 reviews
View
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
21C Museum Hotel St Louis
4.5 star property
9.0
Wonderful
2,129 reviews
View

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top Midtown Hotel Reviews

Frequently asked questions

What is Midtown like?
Travelers are sure to enjoy a stay in St. Louis's Midtown neighborhood. Be sure to check out Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on our traveler data, Element by Marriott St. Louis Midtown is one of the top choices for your stay in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 36 Midtown hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best options available in Midtown.
Where can I learn more about changing or cancelling my trip to Midtown?
To access more information about picking new dates or cancelling your trip to Midtown, go to https://www.expedia.com/service/.
What are the top things to see and do in Midtown?
Sights like Red Flag, Scott Joplin House State Historic Site, and Museum of Contemporary Religious Art can be part of your cultural tour of Midtown. Chaifetz Arena and Washington Avenue Historic District are also a couple of places to visit in the neighborhood. St. Louis Union Station, Hermann Stadium, and .ZACK Theater are just a few of the places to visit in and around Midtown. While you're out sightseeing, Fubar and The Sovereign - St. Louis are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.

Explore a world of travel with Expedia