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Our top choices for Midtown hotels

Element St. Louis Midtown
Element St. Louis Midtown
Residence Inn by Marriott St Louis Downtown
Residence Inn by Marriott St Louis Downtown
Country Hearth Inn & Suites Edwardsville St. Louis
Country Hearth Inn & Suites Edwardsville St. Louis
Hyatt Select St. Louis Airport
Hyatt Select St. Louis Airport
Holiday Inn Express Troy by IHG
Holiday Inn Express Troy by IHG
Super 8 by Wyndham Troy IL/St. Louis Area
Super 8 by Wyndham Troy IL/St. Louis Area
Comfort Inn Edwardsville - St. Louis
Comfort Inn Edwardsville - St. Louis
Motel 6 Hazelwood, MO
Motel 6 Hazelwood, MO
Red Lion Inn & Suites Pontoon Beach
Red Lion Inn & Suites Pontoon Beach
Wingate by Wyndham St. Louis Airport
Wingate by Wyndham St. Louis Airport
Hampton Inn & Suites St. Louis at Forest Park
Hampton Inn & Suites St. Louis at Forest Park
Hampton Inn By Hilton St Louis Airport
Hampton Inn By Hilton St Louis Airport
Comfort Inn & Suites Saint Louis Lafayette Square
Comfort Inn & Suites Saint Louis Lafayette Square
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Holiday Inn Express & Suites Edwardsville by IHG
Holiday Inn Express & Suites Edwardsville by IHG
River City Casino & Hotel
River City Casino & Hotel
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
Best Western Plus Pontoon Beach
Best Western Plus Pontoon Beach
Best Western St. Louis Inn
Best Western St. Louis Inn
Wingate by Wyndham St. Louis/Fenton Route 66
Wingate by Wyndham St. Louis/Fenton Route 66Where to stay in Midtown

Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Soulard
You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Top Midtown Hotel Reviews

Clayton Plaza Hotel & Extended Stay
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