Find hotels in Midtown, St. Louis

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Midtown hotels

Element St. Louis Midtown

Element St. Louis Midtown
3.0 star property
Midtown
9.0 out of 10, Wonderful, (704 reviews)
"Hotel staff and the valet staff were very helpful. This hotel is in an excellent location and there are many places to walk to for food and shopping. Breakfast was amazing with a lot of choices."
United States
Lori
The price is ¥21,642
¥25,305 total
includes taxes & fees
Apr 8 - Apr 9
Element St. Louis Midtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.8 out of 10, Good, (1,002 reviews)
"Beds are nice. Bedrooms are clean. Breakfast was good. Front end staff was attentive and kind. The floors, carpets and elevators need better cleaning"
United States
Maria
The price is ¥18,858
¥22,427 total
includes taxes & fees
Apr 6 - Apr 7
Residence Inn by Marriott St Louis Downtown

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
17.3 km from Midtown
9.4 out of 10, Exceptional, (2,891 reviews)
"Great stay, super clean and friendly staff."
United States
Edmarie
The price is ¥14,381
¥16,932 total
includes taxes & fees
Apr 14 - Apr 15
Pear Tree Inn St. Louis Airport

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
16 km from Midtown
9.2 out of 10, Wonderful, (1,003 reviews)
"The rooms were clean and very quiet."
United States
Erin
The price is ¥17,579
¥21,616 total
includes taxes & fees
Apr 8 - Apr 9
Hyatt Select St. Louis Airport

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
27.6 km from Midtown
8.6 out of 10, Excellent, (684 reviews)
"Room was great,staff friendly! All together a great stay."
United States
Zachary
The price is ¥22,214
¥25,541 total
includes taxes & fees
Apr 5 - Apr 6
Country Hearth Inn & Suites Edwardsville St. Louis

Hampton Inn O'Fallon

Hampton Inn O'Fallon
2.5 star property
26.3 km from Midtown
9.2 out of 10, Wonderful, (831 reviews)
"We had a peaceful, clean and friendly stay. Very nice location. "
United States
Carl
The price is ¥17,620
¥20,436 total
includes taxes & fees
Apr 3 - Apr 4
Hampton Inn O'Fallon

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
27.8 km from Midtown
9.2 out of 10, Wonderful, (855 reviews)
"Very pleasant and accommodating. "
United States
Diana
The price is ¥22,283
¥25,622 total
includes taxes & fees
Apr 5 - Apr 6
Holiday Inn Express & Suites Edwardsville by IHG

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
25.8 km from Midtown
9.6 out of 10, Exceptional, (1,002 reviews)
"Very clean place with great food and friendly staff. "
Canada
Kara
The price is ¥19,176
¥22,433 total
includes taxes & fees
Apr 8 - Apr 9
Drury Inn & Suites Southwest St. Louis

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
17.2 km from Midtown
9.2 out of 10, Wonderful, (1,570 reviews)
"Great location room was nice and clean "
United States
Gabriela
The price is ¥17,458
¥20,555 total
includes taxes & fees
Apr 5 - Apr 6
Wingate by Wyndham St. Louis Airport

Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
16.7 km from Midtown
9.2 out of 10, Wonderful, (1,165 reviews)
"Friendly staff, clean and convenient"
United States
Bethany
The price is ¥18,377
¥21,564 total
includes taxes & fees
Apr 13 - Apr 14
Drury Inn & Suites St. Louis Airport

Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
2.5 star property
Dogtown, 4.8 km from Midtown
9.4 out of 10, Exceptional, (1,008 reviews)
"Great stay, great location"
United States
Michelle
The price is ¥19,526
¥23,027 total
includes taxes & fees
Apr 12 - Apr 13
Hampton Inn & Suites St. Louis at Forest Park

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
23.2 km from Midtown
8.0 out of 10, Very Good, (1,174 reviews)
"Everything was great for overnight stay. "
United States
Regina
The price is ¥14,263
¥16,473 total
includes taxes & fees
Apr 5 - Apr 6
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
29.2 km from Midtown
9.8 out of 10, Exceptional, (1,117 reviews)
"It’s a great place very happy!"
United States
Chris
The price is ¥21,733
¥25,207 total
includes taxes & fees
Apr 12 - Apr 13
Drury Plaza Hotel St. Louis Chesterfield

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
11.9 km from Midtown
9.0 out of 10, Wonderful, (1,507 reviews)
"Nice room, nice stay."
United States
Kailey
The price is ¥16,395
¥21,412 total
includes taxes & fees
Apr 5 - Apr 6
River City Casino & Hotel

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
29.2 km from Midtown
8.0 out of 10, Very Good, (1,006 reviews)
"Great room at low cost. Clean, comfortable, walking distance to Cracker Barrel."
United States
Jerry
The price is ¥11,546
¥12,815 total
includes taxes & fees
Apr 7 - Apr 8
Super 8 by Wyndham Troy IL/St. Louis Area

The Principal Hotel

The Principal Hotel
3.5 star property
21.4 km from Midtown
9.8 out of 10, Exceptional, (222 reviews)
"I love staying here whenever i come to town."
United States
bonnie
The price is ¥15,866
¥17,608 total
includes taxes & fees
Apr 8 - Apr 9
The Principal Hotel

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
29.4 km from Midtown
9.4 out of 10, Exceptional, (746 reviews)
"Shower was amazing, clean room, nice staff, decent breakfast"
United States
Paula
The price is ¥19,558
¥21,706 total
includes taxes & fees
Apr 19 - Apr 20
Holiday Inn Express Troy by IHG

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
2.5 star property
24.8 km from Midtown
9.4 out of 10, Exceptional, (1,000 reviews)
"Will definitely stay here again! "
United States
Sharon
The price is ¥14,381
¥16,625 total
includes taxes & fees
Apr 13 - Apr 14
Pear Tree Inn St. Louis Arnold

Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur
3.0 star property
Creve Coeur, 19.6 km from Midtown
9.2 out of 10, Wonderful, (1,009 reviews)
"Great stay! "
United States
Amy
The price is ¥20,454
¥23,775 total
includes taxes & fees
Apr 12 - Apr 13
Drury Plaza Hotel St. Louis Creve Coeur

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
21 km from Midtown
8.6 out of 10, Excellent, (1,896 reviews)
"Great place to stay"
United States
Kerry
The price is ¥10,405
¥12,720 total
includes taxes & fees
Apr 14 - Apr 15
Motel 6 Hazelwood, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Top Midtown Hotel Reviews

Frequently asked questions

What is Midtown like?
Travelers are sure to enjoy a stay in St. Louis's Midtown neighborhood. Be sure to check out Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on Expedia customer reviews, Element St. Louis Midtown is the highest ranked property in Midtown. This hotel offers free breakfast and an indoor pool. Another top choice in the area is Residence Inn by Marriott St Louis Downtown.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 35 Midtown hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best options available in Midtown.
Where can I learn more about changing or cancelling my trip to Midtown?
To access more information about picking new dates or cancelling your trip to Midtown, go to https://www.expedia.com/service/.
What are the top things to see and do in Midtown?
Explore Midtown's landmarks like Washington Avenue Historic District, Scott Joplin House State Historic Site, and Samuel Cupples House and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighborhood. Favorite places to visit in the surrounding area include St. Louis Union Station, Enterprise Center, and Busch Stadium. While you're out sightseeing, Gateway Arch and .ZACK Theater are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.

Explore a world of travel with Expedia