Midtown, MO
St. Louis





Visit Midtown
Midtown Hotel Deals

Element St. Louis Midtown
Nice property Convenient location
Reviewed on Mar 25, 2026

Residence Inn by Marriott St Louis Downtown
Pulled out the sofa bed and stains all over. Third person (that I paid for was not able to sleep on the mattress). Took pictures showed to front desk and they took the pictures from my phone and said “ok” . Absolutely disgusting.
Reviewed on Mar 9, 2026

Drury Plaza Hotel St. Louis at the Arch
Perfect location for visiting the Gateway Arch and/or a Cardinals game. The happy hour and breakfast were great. Very nice staff and clean, spacious room.
Reviewed on Mar 25, 2026

Pear Tree Inn St. Louis Near Union Station
Great breakfast and loved the daily happy hour!
Reviewed on Mar 25, 2026

Clayton Plaza Hotel & Extended Stay
Stay was wonderful. Would definitely recommend.
Reviewed on Mar 23, 2026

21C Museum Hotel St Louis
Overall a great hotel, nice location, easy valet. It was inconvenient that an elevator was down, we waited for 5 cycles to run before we were able to get to the lobby around breakfast.
Reviewed on Mar 24, 2026
Other neighborhoods around Midtown

The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.

Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.

Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.

The Grove
The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.

Shaw
While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
