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Our top choices for Clayton hotels
8.8 out of 10, Excellent, (3048)
"Clean room, good breakfast and good location "
Martin
The price is ￥14,750
￥17,219 total
includes taxes & fees
Jan 30 - Jan 31, 2026
9.0 out of 10, Wonderful, (230)
"Staff was amazing "
Sham
The price is ￥20,276
￥23,670 total
includes taxes & fees
Jan 18 - Jan 19, 2026
8.8 out of 10, Excellent, (681)
"The gym was amazing! "
Hannah
The price is ￥21,087
￥24,829 total
includes taxes & fees
Jan 2 - Jan 3, 2026
9.2 out of 10, Wonderful, (554)
"The stay was ok even though nothing was explained to be. The hours of restaurant, where the gym is located about the bar in the room nothing. "
Shemelle
The price is ￥77,829
￥90,856 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hampton Inn & Suites Clayton/St. Louis-Galleria AreaClayton
9.0 out of 10, Wonderful, (921)
"Clean room, friendly staff."
Patrick George
The price is ￥17,777
￥20,930 total
includes taxes & fees
Jan 19 - Jan 20, 2026
9.2 out of 10, Wonderful, (195)
"Clean rooms. Great location. Get a room facing the park. "
Gerhardt
The price is ￥25,111
￥30,193 total
includes taxes & fees
Jan 23 - Jan 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Clayton
Find the best Clayton areas and neighborhoods for the activities you enjoy most.
Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Busch Stadium or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.
Top Clayton Hotel Reviews
Drury Plaza Hotel St. Louis at the Arch
10/10 Excellent
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