Find hotels in La Mesa, CA from ￥9,264

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Dec 9 - Dec 10
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Dec 10 - Dec 11
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Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

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Our top choices for La Mesa hotels

Lobby
Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego

2.5 star property
La Mesa
8.2 out of 10, Very Good, (1007)
"Clean room, great breakfast, pleasant staff. It was comfortable. "
United States
Vonda
The price is ￥15,098
￥16,608 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Best Western Plus La Mesa San Diego
Outdoor pool, pool umbrellas, sun loungers
Heritage Inn La Mesa

Heritage Inn La Mesa

2.0 star property
La Mesa
7.0 out of 10, Good, (1194)
"room was clean and staff very friendly"
United States
Charles
The price is ￥8,878
￥9,797 total
includes taxes & fees
Dec 14 - Dec 15
Heritage Inn La Mesa
Suite, Multiple Beds, Kitchenette | Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Holiday Inn Express La Mesa Near SDSU by IHG

Holiday Inn Express La Mesa Near SDSU by IHG

3.0 star property
La Mesa
8.2 out of 10, Very Good, (449)
"Very accommodating "
United States
Todd
The price is ￥21,032
￥23,177 total
includes taxes & fees
Dec 17 - Dec 18
Holiday Inn Express La Mesa Near SDSU by IHG
Blackout drapes, free WiFi, bed sheets
Motel 6 La Mesa, CA

Motel 6 La Mesa, CA

2.0 star property
La Mesa
7.2 out of 10, Good, (1001)
"Easy parking, clean, nice staff, safe"
United States
Martha
The price is ￥14,020
￥15,422 total
includes taxes & fees
Dec 14 - Dec 15
Motel 6 La Mesa, CA
Blackout drapes, free WiFi, bed sheets
Motel 6 La Mesa, CA - San Diego

Motel 6 La Mesa, CA - San Diego

2.0 star property
La Mesa
7.4 out of 10, Good, (976)
"Room was clean. Quick and easy check in. "
United States
Brian
The price is ￥13,396
￥14,759 total
includes taxes & fees
Dec 14 - Dec 15
Motel 6 La Mesa, CA - San Diego
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 star property
National City
9.2 out of 10, Wonderful, (3510)
"Great friendly staff "
United States
mohammed
The price is ￥18,089
￥19,933 total
includes taxes & fees
Dec 16 - Dec 17
Best Western Plus Marina Gateway Hotel
Outdoor pool
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3148)
"Great stay"
United States
Laurence
The price is ￥23,555
￥34,477 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hard Rock Hotel San Diego
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
Downtown San Diego
8.4 out of 10, Very Good, (6036)
"Always an amazing stay"
United States
Jana
The price is ￥20,993
￥28,845 total
includes taxes & fees
Dec 24 - Dec 25
Wyndham San Diego Bayside
Exterior
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1230)
"Very nice clean room and amenities and staff was pleasant and we love the location. "
United States
Arnold
The price is ￥21,293
￥24,687 total
includes taxes & fees
Dec 14 - Dec 15
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Front of property - evening/night
Ayres Lodge Alpine

Ayres Lodge Alpine

3.0 star property
Alpine
9.2 out of 10, Wonderful, (1004)
"Great hotel."
United States
TOMLINSON,
The price is ￥15,283
￥16,536 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Ayres Lodge Alpine
Serves dinner and happy hour
The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2694)
"Clean facilities and friendly staff!"
United States
EMMA
The Horton Grand, Downtown/Gaslamp Quarter
Exterior
Viejas Casino & Willows Hotel

Viejas Casino & Willows Hotel

4.0 star property
Alpine
9.2 out of 10, Wonderful, (1002)
"Nice location and the ambient was the best."
United States
ivan
The price is ￥19,212
￥23,951 total
includes taxes & fees
Dec 10 - Dec 11
Viejas Casino & Willows Hotel
Property entrance
The Bristol Hotel San Diego

The Bristol Hotel San Diego

3.5 star property
Downtown San Diego
8.6 out of 10, Excellent, (1445)
"So clean, Very Nice staff, convenient location ! "
United States
Cindy
The Bristol Hotel San Diego
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

3.5 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1010)
"very good location, good and quiet AC system (not the noise window AC)."
United States
Henry
The price is ￥17,293
￥19,671 total
includes taxes & fees
Dec 10 - Dec 11
Gaslamp Plaza Suites
Exterior
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 star property
Point Loma
9.2 out of 10, Wonderful, (3182)
"Great stay and location!"
United States
Jason
The price is ￥18,367
￥21,112 total
includes taxes & fees
Dec 15 - Dec 16
Bay Club Hotel & Marina
Garden
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2957)
"Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego."
United States
Eric
The price is ￥23,703
￥27,245 total
includes taxes & fees
Dec 14 - Dec 15
Legacy Resort Hotel & Spa
Premium bedding, pillowtop beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1000)
"Great location "
United States
Mohammad
The price is ￥16,125
￥23,198 total
includes taxes & fees
Dec 30 - Dec 31
Staypineapple, Hotel Z, Gaslamp San Diego
2 outdoor pools, a heated pool, sun loungers
The Dana on Mission Bay

The Dana on Mission Bay

3.5 star property
Mission Bay
9.0 out of 10, Wonderful, (3914)
"The room was spotless the bed was so comfy the Amenities were great!! The food at the restaurant very delish"
United States
Emily
The price is ￥23,144
￥29,710 total
includes taxes & fees
Jan 8 - Jan 9, 2026
The Dana on Mission Bay
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Diego Mission Bay

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

3.0 star property
Pacific Beach
8.0 out of 10, Very Good, (1422)
"Great place We will stay here again. "
United States
Derek
The price is ￥15,218
￥17,496 total
includes taxes & fees
Dec 15 - Dec 16
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
Front of property
The Sofia Hotel

The Sofia Hotel

3.5 star property
Downtown San Diego
8.4 out of 10, Very Good, (1645)
"Great location and history to the hotel "
United States
Stephanie
The price is ￥17,390
￥23,870 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Sofia Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Great weekend hotel deals in La Mesa, CA

Showing deals for:Dec 19 - Dec 21

Image gallery for Cozy Casita

Fridge, microwave, oven, stovetop

Cozy Casita

La Mesa
9.4/10Exceptional (8 reviews)
10% off
Price is ￥22,013
￥76,058 total
includes taxes & fees
Cozy Casita
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Where to stay in La Mesa

Find the best La Mesa areas and neighborhoods for the activities you enjoy most. Learn more about La Mesa
Learn more about La Mesa

Mount Helix

While there might not be top attractions in Mount Helix, you can explore the larger area and discover places like Mount Helix Park and The Magnolia.

Windsor Hills

If you're looking for some top things to see and do in Windsor Hills and surrounding area, you can visit Cal Coast Credit Union Open Air Theater and Viejas Arena.

Learn more about La Mesa

Nestled between rolling hills, this charming suburb offers hiking trails through Mission Trails Park and Lake Murray's scenic waterfront paths. Visit the vibrant farmers market on Fridays, then explore the antique shops and local breweries along La Mesa Boulevard's historic district.

See all hotels in La Mesa
View from Mount Helix, in La Mesa, near San Diego, California

Top La Mesa Hotel Reviews

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla

10/10 Excellent
"I stayed here every time we would come down here when I was younger on family trips. Now I’m back years later with my boyfriend everything was Perfect and great service all around "
katherine 3-night trip
Posted 23 hours ago
Embassy Suites by Hilton San Diego La Jolla

More cheap stays in La Mesa

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2485 Hotel Circle Place San Diego CA
The price is ￥18,500 per night from Dec 16 to Dec 17
￥18,500
￥21,265 total
Dec 16 - Dec 17
includes taxes & fees
8/10 Very Good! (2,305 reviews)

Frequently asked questions

What's the best place for a stay in La Mesa?
Best Western Plus La Mesa San Diego is a favorite property for Expedia customers. This hotel offers free breakfast and an outdoor pool. Reviews from our site also recommend Holiday Inn Express La Mesa Near SDSU by IHG and Motel 6 La Mesa, CA as top choices for your visit. See all available top hotels, or vacation rentals in La Mesa.
What's the top vacation rental in La Mesa?
Spanish Casita in the Village of La Jolla - Walk to Everything: This vacation home near La Mesa is located near the beach and has a balcony, a selection of games, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a microwave, and a coffee maker. See all vacation rentals in La Mesa.
If I need to cancel my hotel reservation in La Mesa, will I receive a refund?
Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.
Where can I learn more about changing or cancelling my trip to La Mesa?
To find more details about changing or cancelling your trip to La Mesa, head over to our customer service page.
What's the best place to stay for a family vacation in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a hotel with an outdoor pool and free breakfast, and it's a top choice on Expedia for families. Kids of all ages will also enjoy a visit to Computer Museum of America. Find more child-friendly accommodations in La Mesa.
What is the top LGBTQ-friendly hotel in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Heritage Inn La Mesa is another good option for your trip. See all available hotels listed as LGBTQ-friendly in La Mesa.
What's the best pet-friendly accommodation in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a top hotel for people traveling with their pets, and offers an outdoor pool and free WiFi for its human guests. Two other good options for you and your pet's trip include Motel 6 La Mesa, CA - San Diego and Motel 6 La Mesa, CA. See more pet-friendly hotel accommodations in La Mesa.
What are some accommodations with pools in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a top hotel with a pool, free buffet breakfast, and free WiFi. Private Detatched Guest House in Mt. Helix is another choice with an onsite pool. View all hotels with pools in La Mesa.
What's the top hotel in La Mesa with an on-site water park or a water park nearby?
Private Detatched Guest House in Mt. Helix is a popular guesthouse featuring water park access, an outdoor pool, and in-room kitchens. Check out all hotels with or near waterparks in La Mesa.
What is the best hotel near San Diego International Airport (SAN)?
Sheraton San Diego Hotel and Marina is a popular 4-star hotel featuring a marina and 3 outdoor pools. It's located a short 0.4 mi (0.6 km) from San Diego Intl. Airport. Other places to stay near the airport are  Hampton Inn & Suites San Diego Airport Liberty Station and Wyndham San Diego Bayside.
What is staying in La Mesa like?
Families will find kid-friendly activities in La Mesa, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its shopping, zoo, and entertainment choices. Around the area, top sights include San Diego Zoo, Petco Park, and Port of San Diego. In La Mesa, there are 155 hotels and other accommodations to choose from. Find out more about La Mesa.
What should I see while I'm in La Mesa?
A couple of favorite places to visit are Mount Helix Park and Computer Museum of America. You'll also find San Diego Zoo and Petco Park in the area. Check out what more to see and do in Expedia's La Mesa guide.
What's the best way to get around La Mesa?
You can take advantage of metro transit at La Mesa Boulevard Station, Spring St Trolley Station, and 70th St. Trolley Station. If you want to venture out around the area, you may want a rental car in La Mesa for your journey.
What's the seasonal weather like in La Mesa?
The hottest months are usually August and September with an average temp of 72°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for La Mesa is 12 inches.

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