Missouri Resorts & Hotels with Spas from ￥18,589

A city square with a fountain, modern buildings, and a historic tower.

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A cityscape with a prominent historic building featuring arched entrances and a large central dome, surrounded by modern skyscrapers and a well-maintained park with a fountain.

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Our top choices for Missouri hotels with a spa

Couples treatment rooms, hot tub, body treatments, hydrotherapy

The Elms Hotel & Spa, a Destination by Hyatt Hotel

Excelsior Springs

Immerse in a rejuvenating spa retreat with 17 treatment rooms, hot tubs, and beautiful garden views at this historic hotel.

￥32,132 total

includes taxes & fees

Aug 17 - Aug 18

Couples treatment rooms, body treatments, hydrotherapy, aromatherapy

Camden on the Lake Resort & Spa

Lake Ozark

Relax at this lakeside resort with four treatment rooms at Spa 54, featuring hot stone massages, hydrotherapy, and couples' services.

￥31,259 total

includes taxes & fees

Aug 10 - Aug 11

Couples treatment rooms, hot tub, body treatments, aromatherapy

Four Seasons Hotel St Louis

Downtown St. Louis

Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.

￥71,209 total

includes taxes & fees

Jul 22 - Jul 23

Margaritaville Lake Resort Lake of the Ozarks

Osage Beach

Lakeside spa resort with golf course offers rejuvenating massages, body treatments, and poolside relaxation.

￥38,825 total

includes taxes & fees

Aug 2 - Aug 3

Embassy Suites by Hilton St. Louis St. Charles

St. Charles

￥27,395 total

includes taxes & fees

Aug 9 - Aug 10

Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

￥29,052 total

includes taxes & fees

Aug 17 - Aug 18

Hyatt Regency St. Louis at The Arch

Downtown St. Louis

￥29,129 total

includes taxes & fees

Jul 31 - Aug 1

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Clayton

￥24,930 total

includes taxes & fees

Aug 9 - Aug 10

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Top Missouri Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent

"We stayed for 4 nights and it was great! Staff was helpful, room was clean. We didn't use the pool so I can't speak on that. I was glad they had guest laundry and vending machines. There was plenty of parking. Breakfast was ok, what you expect from a hotel breakfast. This is where I will stay anytime I'm in the area."

Best Western Plus Kansas City Sports Complex Hotel

10/10 Excellent

"Was this the most aesthetically updated hotel I’ve ever stayed at? No. But it was very clean and comfortable. And, when we ended up staying an extra night because our car broke down, the staff (especially Mercedes) was exceedingly helpful and caring. They made a terrible situation bearable. So thankful! Also, the breakfast buffet was phenomenal! We were there during World Cup matches and the patrons resembled the United Nations. It was great to hear staff members use Spanish to help to communicate with visitors. Such a great stay! Super convenient to stadiums."

University Plaza Hotel and Convention Center Springfield

10/10 Excellent

"Always a nice stay at the University Plaza. Would love if there were more food options at the hotel (the coffee shop does not have a good variety of breakfast or lunch options, and there’s no restaurant on site for those without a vehicle.) Otherwise, accommodations are very nice. Beds are very comfortable."

Lodge Of The Ozarks

10/10 Excellent

"No complaints. Nice hotel close to several restaurants and fun and things to do. Only slight word of caution, if you aren't Christian and are offended by Christianity, they play christian music in the public spaces and have bibles out and open to a specific page in your room. No one is trying to persuade you, but it is definitely run by Christians. Personally, I like it as a Christian. However, I respect all belief systems and felt it was worth mentioning."

Thousand Hills Resort Hotel

8/10 Good

"Rooms are outdated, but clean. Beds are comfortable. Bathrooms are small and the toilet are really low. Breakfast is a buffet, not bad. Dinner I had chicken fried steak really good, hubby had meatloaf he didn’t like it at all. The bar is really nice the bartender is very nice and social. Not crazy about the parking lot, not very many handicap spaces for this size of a hotel. The pool is not really very big, to many kids, adult swim is at 10pm to 12 well there no sun then and that sucks."

Westgate Branson Woods Resort and Cabins

8/10 Good

"The grounds were beautiful. They put us in a cabin split into 4 rooms. It was a nice room, although smaller than the pictures. Maid service is not available in the cabins, but the desk will bring anything needed. The big outdoor pool has the hot tub. It's hot, but there aren't jets, just bubbles. The pool and area are nice. There's a convenience store near the pool, but a short drive to Dollar General is less expensive. When checking in, opt out of the next day breakfast, unless you want to hear the sales presentation on owning vacation usage of the property, but you might qualify for a free show. Make sure to take to hike to the waterfall. It's worth the walk, but the trail is not for everyone, as there are many of rocks and snakes. All in all, we are glad we stayed."

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Top Cities in Missouri

Kansas City

Check availability on Missouri Resorts & Hotels with Spas

Our top choices for Missouri hotels with a spa

The Elms Hotel & Spa, a Destination by Hyatt Hotel

Camden on the Lake Resort & Spa

Four Seasons Hotel St Louis

Margaritaville Lake Resort Lake of the Ozarks

Embassy Suites by Hilton St. Louis St. Charles

Drury Plaza Hotel St. Louis at the Arch

Hyatt Regency St. Louis at The Arch

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Drury Inn & Suites St. Louis Arnold

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Top Missouri Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Best Western Plus Kansas City Sports Complex Hotel

University Plaza Hotel and Convention Center Springfield

Lodge Of The Ozarks

Forest Park Hotel by MDR

Thousand Hills Resort Hotel

Hyatt Vacation Club at The Lodges at Timber Ridge, Branson

Westgate Branson Woods Resort and Cabins

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Resorts & Hotels with Spas in Missouri from ￥18,589

Change your mind

Treat yourself

Be picky

Top Cities in Missouri

Kansas City

Check availability on Missouri Resorts & Hotels with Spas

Our top choices for Missouri hotels with a spa

The Elms Hotel & Spa, a Destination by Hyatt Hotel

Camden on the Lake Resort & Spa

Four Seasons Hotel St Louis

Margaritaville Lake Resort Lake of the Ozarks

Embassy Suites by Hilton St. Louis St. Charles

Drury Plaza Hotel St. Louis at the Arch

Hyatt Regency St. Louis at The Arch

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Drury Inn & Suites St. Louis Arnold

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Top Missouri Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Explore a world of travel with Expedia