A calm lake surrounded by trees and vegetation.

Find 4 Star Hotels in Southwest Illinois, IL from ￥22,107

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Check availability on Southwest Illinois 4 Star Hotels

This weekend
Jul 3 - Jul 5
Next weekend
Jul 10 - Jul 12

Our top choices for Southwest Illinois 4-star hotels

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Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights
3.0 star property
Fairview Heights
9.2 out of 10, Wonderful, (1,016 reviews)
"Great place to stay"
United States
Brad
The price is ￥15,220
￥17,195 total
includes taxes & fees
Jul 26 - Jul 27
Drury Inn & Suites St. Louis Fairview Heights
Lobby lounge

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.5 star property
Mount Vernon
9.6 out of 10, Exceptional, (1,713 reviews)
"A nice stay"
United States
DAVID
The price is ￥21,049
￥23,684 total
includes taxes & fees
Jul 5 - Jul 6
Drury Plaza Hotel Mt. Vernon
Deluxe Studio Suite, 1 King Bed, Non Smoking | Pillowtop beds, in-room safe, desk, laptop workspace

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon
2.0 star property
O'Fallon
6.6 out of 10, (1,019 reviews)
"Bed was comfy and shower was hot. No complaints as I was passing through and just looking for a place to lay my head! Would stay here again!"
United States
Rebekah
The price is ￥8,744
￥10,054 total
includes taxes & fees
Jul 1 - Jul 2
Super 8 by Wyndham O'Fallon
Breakfast, dinner and brunch served

The Principal Hotel

The Principal Hotel
3.5 star property
Columbia
9.6 out of 10, Exceptional, (324 reviews)
"Great hotel and nice staff!"
United States
Michelle
The price is ￥16,834
￥18,683 total
includes taxes & fees
Jul 2 - Jul 3
The Principal Hotel
Standard King Room with Whirlpool - Non Smoking | Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Inn O'Fallon IL - St. Louis

Quality Inn O'Fallon IL - St. Louis
3.0 star property
O'Fallon
7.4 out of 10, Good, (1,006 reviews)
"Great place to stay"
United States
Tammy
The price is ￥11,424
￥13,135 total
includes taxes & fees
Jul 6 - Jul 7
Quality Inn O'Fallon IL - St. Louis
2 Queen Bed Suites | Desk, blackout drapes, iron/ironing board, free WiFi

Welcome Suites

Welcome Suites
2.0 star property
O'Fallon
6.0 out of 10, (284 reviews)
"Was a nice place to stay very affordable "
United States
Daren
Welcome Suites
Free daily buffet breakfast

Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights
2.5 star property
Fairview Heights
7.4 out of 10, Good, (22 reviews)
"The room was clean well kept and a good location!!"
United States
Landra
The price is ￥12,940
￥14,620 total
includes taxes & fees
Jul 8 - Jul 9
Best Western St. Louis Fairview Heights
Indoor pool, outdoor pool

Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
3.0 star property
O'Fallon
9.6 out of 10, Exceptional, (1,008 reviews)
"Very clean hotel, there are a nice pool,tasted breakfast."
United States
Vitalii
The price is ￥20,078
￥23,287 total
includes taxes & fees
Jul 6 - Jul 7
Drury Inn & Suites St. Louis O'Fallon, IL
Lobby

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1,012 reviews)
"Clean room, great breakfast and evening drinks & food. Friendly staff."
United States
Brandy
The price is ￥20,240
￥24,283 total
includes taxes & fees
Jul 5 - Jul 6
Drury Inn & Suites Marion
In-room safe, desk, iron/ironing board, free WiFi

Comfort Suites Fairview Heights - St. Louis

Comfort Suites Fairview Heights - St. Louis
2.5 star property
Fairview Heights
6.4 out of 10, (1,005 reviews)
"Very nice rooms. "
United States
Jennifer
The price is ￥12,922
￥14,599 total
includes taxes & fees
Jul 6 - Jul 7
Comfort Suites Fairview Heights - St. Louis
Suite, 1 King Bed, Non Smoking (Accessible Tub) | Desk, iron/ironing board, free WiFi, bed sheets

Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255
2.5 star property
Cahokia
7.4 out of 10, Good, (1,002 reviews)
"Decent place to stay. I appreciate the breakfast option. Staff very friendly."
United States
Rafael
The price is ￥12,541
￥14,172 total
includes taxes & fees
Jul 13 - Jul 14
Quality Inn & Suites near St. Louis and I-255
Lobby

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
Edwardsville
8.4 out of 10, Very Good, (881 reviews)
"Enjoyed my stay! Hotel was nice and convenient"
United States
Renita M.
The price is ￥15,416
￥17,725 total
includes taxes & fees
Jul 27 - Jul 28
Comfort Inn Edwardsville - St. Louis
Sauna, hot tub, body treatments, hot stone massages

Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
4.5 star property
Carterville
9.4 out of 10, Exceptional, (471 reviews)
"Nice hotel!"
United States
Monique
The price is ￥21,038
￥23,348 total
includes taxes & fees
Jul 5 - Jul 6
Walker's Bluff Casino Resort
Breakfast, lunch and dinner served

Radisson Hotel Fairview Heights - St. Louis

Radisson Hotel Fairview Heights - St. Louis
3.0 star property
Fairview Heights
7.6 out of 10, Good, (645 reviews)
"Friendly staff, food on site"
United States
Tami
The price is ￥15,284
￥17,268 total
includes taxes & fees
Jul 29 - Jul 30
Radisson Hotel Fairview Heights - St. Louis
Lobby

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,055 reviews)
"Quick and easy check in, fruendly staff, bed and pillows were super comfy and the breakfast was great. "
United States
Todd
The price is ￥19,845
￥22,348 total
includes taxes & fees
Jul 5 - Jul 6
Comfort Suites Mount Vernon
Indoor pool

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
Troy
8.0 out of 10, Very Good, (1,000 reviews)
"Good customer service well put together hotel"
United States
Donta
The price is ￥11,659
￥12,940 total
includes taxes & fees
Jul 1 - Jul 2
Super 8 by Wyndham Troy IL/St. Louis Area
Room, 1 Queen Bed, Jetted Tub | Blackout drapes, free WiFi, bed sheets

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
Granite City
7.8 out of 10, Good, (684 reviews)
"My room was clean with a comfortable bed at a reasonable price. A better option than other similar hotels in the vicinity."
United States
Jim
The price is ￥11,645
￥13,183 total
includes taxes & fees
Jul 1 - Jul 2
Red Lion Inn & Suites Pontoon Beach
Lobby

Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville
3.0 star property
Eastport
9.6 out of 10, Exceptional, (1,014 reviews)
"We returned to this property after staying there last week. It was a great value."
United States
Maryanna
The price is ￥17,163
￥19,734 total
includes taxes & fees
Jul 5 - Jul 6
Drury Inn & Suites St. Louis Collinsville
Soundproofing, free WiFi

Red Lion Inn & Suites Caseyville

Red Lion Inn & Suites Caseyville
2.0 star property
Caseyville
5.2 out of 10, (291 reviews)
"Good place to get a night's sleep, plenty of parking, not far from Cahokia Mounds"
United States
Michael
The price is ￥10,185
￥11,465 total
includes taxes & fees
Jul 1 - Jul 2
Red Lion Inn & Suites Caseyville
Indoor pool

Best Western Troy Hotel

Best Western Troy Hotel
2.5 star property
Troy
8.0 out of 10, Very Good, (998 reviews)
"We stayed at the best western in May 2026. The room was very clean, staff was helpful, we had all that we needed. The breakfast was also great. We would definitely stay here again."
United States
Joyce
The price is ￥12,810
￥14,217 total
includes taxes & fees
Jul 6 - Jul 7
Best Western Troy Hotel
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Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

See all hotels in Southwest Illinois
A swampy area with tall, thin trees and water reflecting the sky.
Photo by Carl Anderson
Open Photo by Carl Anderson

Top Southwest Illinois Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southwest Illinois?
According to reviews by Expedia customers, DoubleTree by Hilton Collinsville - St. Louis is among the favorites in Southwest Illinois. Offering lots of handy amenities and an unrivaled level of service, this 4-star hotel in Collinsville promises an enjoyable stay.
How much does it cost to stay in a 4-star hotel in Southwest Illinois?
We can help you quickly track down the perfect 4-star hotel for your stay in Southwest Illinois. Use our handy filter tool to fine-tune your search by things like budget, amenities and property star rating and get access to terrific deals in a few clicks.

  • Search for the lowest price from ￥22,107

What's the difference between 5-star and 4-star hotels in Southwest Illinois?
If you decide to vacation at a 4-star hotel in Southwest Illinois, you'll typically find loads of amenities to ensure you're relaxed, such as a gym, pool and restaurant. You can enjoy high-quality service and upscale surroundings. Opt for a 5-star hotel and you'll have access to a few more perks — think on-site spas, concierge assistance and indulgent turndown services. You're likely to get additional amenities and first-rate services at a 5-star retreat, but both are superb options for luxury travelers.

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