
Southwest Illinois Vacations
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Photo by Southernmost Illinois Tourism Bureau
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Where to stay in Southwest Illinois
Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois

Eastport
If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.
Find the Best Southwest Illinois Vacation Packages
Southwest Illinois Hotel Deals

Drury Plaza Hotel Mt. Vernon
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is ¥14,051 per night from Oct 5 to Oct 6
¥14,051
¥15,892 total
Oct 5 - Oct 6
includes taxes & fees
9.6/10 Exceptional! (1,468 reviews)
"Clean room… friendly staff… pool looks amazing and so does the hot tub… food is close by …"
Reviewed on Sep 25, 2025

Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr, East St. Louis, IL
Fully refundableReserve now, pay when you stay
The price is ¥10,337 per night from Oct 26 to Oct 27
¥10,337
¥11,681 total
Oct 26 - Oct 27
includes taxes & fees
7.4/10 Good! (1,011 reviews)
"Great hotel for the price"
Reviewed on Sep 21, 2025

Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr, Fairview Heights, IL
Fully refundableReserve now, pay when you stay
The price is ¥13,976 per night from Oct 2 to Oct 3
¥13,976
¥15,789 total
Oct 2 - Oct 3
includes taxes & fees
9/10 Wonderful! (1,020 reviews)
Housekeeping problem
"They need to teach the housekeeping staff to not park their carts in the middle of the hallway. This makes it really hard to navigate the hallway with luggage."
Reviewed on Sep 18, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Southwest Illinois

Southern Illinois University
Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Ferne Clyffe State Park
You can take time to visit Ferne Clyffe State Park during your travels to Goreville. While you're in the area, wander around the parks.
What to do in Southwest Illinois

Immersive Potsticker Cooking Class in Chicago
¥11,135
per adult
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.