Find Adults Only Resorts & Hotels in Panama City
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Panama City Adults Only Resorts & Hotels
Top Panama City Adults Only Resorts & Hotels
Tantalo Hotel
Casco Viejo
8.8 out of 10, Excellent, (273)
"My favorite place in Casco Viejo. "
Michael
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Panama City Hotel Reviews
Explore a world of travel with Expedia
Top neighborhoods for Adults Only Resorts & Hotels
More Hotel Options in Panama City
- All-inclusive Hotel in Panama City
- Beach Hotels in Panama City
- Boutique Hotels in Panama City
- Casinos in Panama City
- Cheap Hotels in Panama City
- Gay friendly Hotels in Panama City
- Historic Hotels in Panama City
- Hotels with Early Check-in in Panama City
- Hotels with a Pool in Panama City
- Luxury Hotels in Panama City
- Resorts & Hotels with Spas in Panama City
- Winery Hotels in Panama City
More Accommodation Types in Panama City
Panama City Hotels by Star Rating
Explore more hotels
- Decapolis Hotel Panama City
- The Executive Hotel
- Hyatt Regency Panama City
- Waymore Hotel Spa & Casino
- Hotel El Panama by Faranda Grand, a member of Radisson Individuals
- Studio Coliving
- Ramada Plaza by Wyndham Panama Punta Pacifica
- Arcadia Condo Suites
- Sofitel Legend Casco Viejo, Panama City
- The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
- Residence Inn by Marriott Panama City
- American Trade Hotel
- Hilton Panama
- MARINN Tropical Vibes Hotel
- Hotel Ojos del Rio
Expedia's Latest Trends
Hotels
- Melia Paulista
- Meriton Suites North Sydney
- Guest Houses Yokohama
- Hotels in Tomisato
- The Gran Resort Elegante Karuizawa
- ibis Melbourne Hotel and Apartments
- International Garden Hotel Narita
- ART HOTEL Aomori
- The Capitol Hotel Tokyu
- Hotel Yae no Midori Tokyo
- MarriottHotelsResorts Hotels in Hakone
- Ooike Hotel
- Crowne Plaza Hotel Foster City - San Mateo by IHG
- Ka Laʻi Waikiki Beach, LXR Hotels & Resorts
- Hotels near Nishikujo Station
Flights
- Flights from Detroit (DTW) to Nagoya (NGO)
- Flights from Fukuoka (FUK) to Montreal (YUL)
- Flights from Narita (NRT) to Istanbul (SAW)
- Flights from Tokyo (HND) to Manila (MNL)
- Flights from Nagoya (NGO) to Los Angeles (LAX)
- Flights from Manila (MNL) to Naha (OKA)
- Flights to Bali
- Flights from Boston (BOS) to London (LHR)
- Kenya Airways
- Hawaiian Airlines Narita (NRT) to Honolulu (HNL) flights
Activities
Packages
General