Find Resorts & Hotels with Spas in Panama City

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Check availability on Panama City Resorts & Hotels with Spas

Tonight
Dec 30 - Dec 31
Tomorrow
Dec 31 - Jan 1
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Panama City hotels with a spa

Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1851)
"Better than expected: Location, transportation to and from airport, pool area tropical and comfortable. "
United States
Marty
The price is ￥19,504
￥21,454 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Riande Aeropuerto Hotel & Casino
Couples treatment rooms, sauna, hot tub, steam room, Turkish bath
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1327)
"Lovely breakfast and very clean and friendly staff!!!"
United States
Ravindra
The price is ￥36,425
￥40,068 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Megapolis Hotel Panamá
Couples treatment rooms, sauna, hot tub, steam room, Turkish bath
Decapolis Hotel Panama City

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1470)
"Excellent stay. Wonderful staff, good location and excellent breakfast"
United States
Michael
The price is ￥21,932
￥24,125 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Decapolis Hotel Panama City
Executive Suite, 1 King Bed, Partial Ocean View | Bathroom | Separate tub and shower, designer toiletries, hair dryer, slippers
JW Marriott Panama

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1005)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is ￥41,956
￥46,151 total
includes taxes & fees
Jan 30 - Jan 31, 2026
JW Marriott Panama
Couples treatment rooms, sauna, steam room, body treatments
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very Good, (1003)
"Great place and location, excellent food choices! "
United States
Francisco
The price is ￥36,921
￥40,613 total
includes taxes & fees
Jan 11 - Jan 12, 2026
The Westin Playa Bonita Panama
View from property
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2148)
"Great location of the hotel with a lovely breakfast and friendly staff"
United States
fouad
The price is ￥16,837
￥18,521 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Plaza Paitilla Inn Hotel
Couples treatment rooms, body treatments, aromatherapy
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (568)
"Amazing hotel , location , staff and amenities . Clean, elegant , great service. "
United States
Nicole
The price is ￥55,681
￥61,249 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Sofitel Legend Casco Viejo, Panama City
Couples treatment rooms, steam room, Turkish bath, body treatments
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (644)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ￥33,806
￥37,187 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Couples treatment rooms, sauna, hot tub, steam room, body treatments
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
4.0 star property
Veracruz
7.6 out of 10, Good, (1000)
"Food and drinks were amazing! "
Canada
Adrienne
The price is ￥62,544
￥62,544 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Dreams Playa Bonita Panama - All Inclusive
Massage in accommodation
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1000)
"Nice hotel in the historic center, excellent location for sightseeing and walking around at night."
United States
Antonio
The price is ￥55,572
￥61,129 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Central Hotel Panama Casco Viejo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Great Staff. Wonderful berakfast. Pool guy worked very hard to straighten lounge chairs, bring freah towels, lower umbrella. Room was on 27th floor with fogged over window. So we requested a different room with a view. They accommodated and gave us 31st floor with a great view. Overall a great experience. We took Uber everywhere we needed to go. Was inexpensive to Uber. For day trips old town was our favorite, Anton Hill hike, and the Causway were fun. "
Jacque 5-night trip
Posted 12 hours ago
Hotel Riu Plaza Panama

Frequently asked questions

Looking to vacation at a spa hotel in Panama City?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers highly recommend Panama City for its array of shops and gourmet restaurants—your day tour starts here. Be sure to enjoy the cafes during your stay. Spa hotels are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping mall, and a rooftop terrace. Enjoy a facial, body scrub, or detox wrap at the onsite spa. Other popular spa hotels in Panama City include Las Americas Golden Tower Panama and Sheraton Grand Panama.
How many spa hotels are there in Panama City?
Expedia has 24 spa hotels to choose from in Panama City.
What's there to see and do in Panama City?
Enjoy Panama City with a stop at Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have a little extra time during your trip, you might want to check out Uruguay Street and Crown Casino.
What is a Panama City spa hotel?
Spa hotels in Panama City have full on-site spas which offer services like massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.

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