
Panama City Vacations
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Where to stay in Panama City
Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City

Casco Viejo
4.5/5(178 area reviews)
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.
Find the Best Panama City Vacation Packages
Panama City Hotel Deals

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
The price is ¥17,632 per night from Oct 5 to Oct 6
¥17,632
¥19,395 total
Oct 5 - Oct 6
includes taxes & fees
9/10 Wonderful! (4,338 reviews)
"Breakfast was amazing"
Reviewed on Sep 26, 2025

Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ¥19,927 per night from Oct 12 to Oct 13
¥19,927
¥21,920 total
Oct 12 - Oct 13
includes taxes & fees
8.4/10 Very Good! (952 reviews)
"The Sheraton is a large property, so the size lends itself to several dining options, a very large gym, spacious areas to hang out. WiFi coverage was excellent."
Reviewed on Sep 24, 2025

Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is ¥13,374 per night from Oct 18 to Oct 19
¥13,374
¥14,711 total
Oct 18 - Oct 19
includes taxes & fees
9/10 Wonderful! (503 reviews)
"Very comfortable bed, thick carpets, all good quality. Lovely view from the 8th floor pool. Would be great if breakfast could start a little earlier than 6.30am but otherwise perfect."
Reviewed on Sep 25, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Panama City

Avenida Balboa
4/5(554 reviews)
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Panama Canal Railway
4/5(10 reviews)
Enjoy an outing to Panama Canal Railway during your stay in Ancon. Stroll along the seaside or visit the shops in this culturally rich area.
Albrook Shopping Mall
4/5(605 reviews)
You can enjoy some retail therapy with a trip to Albrook Shopping Mall, a favorite shopping spot in Ancon. Amble around this culturally rich area's seaside and enjoy its top-notch restaurants.
What to do in Panama City

Day Tour in San Blas Islands All Included Visiting 4 Islands
¥21,826
per adult
94% of travellers recommend

Panama City Visit an Indian town Embera and waterfall with lunch
¥7,324
per adult
94% of travellers recommend
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