Panama City Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ¥109,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
A waterfront cityscape with historic buildings and a prominent clock tower.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A cityscape with modern skyscrapers, including a distinctive twisting tower.

Bella Vista

2 out of top 10 points of interest in this area

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Luxor Towers might round out your trip.

A bridge over a body of water with several boats.

San Francisco

1 out of top 10 points of interest in this area

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

A cityscape at sunset with tall buildings silhouetted against the sky.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Find the Best Panama City Vacation Packages

Things to do in and around Panama City

Shopping

In Panama City, visit Albrook Shopping Mall for a vibrant mix of entertainment and shopping. Explore Uruguay Street for local boutiques and family-friendly vibes. For a unique experience, check out the National Craft Market for authentic Panamanian crafts and souvenirs.

Recreation

Estadio Rommel Fernandez offers an energetic atmosphere for sports enthusiasts, perfect for invigorating workouts or enjoying local games. For a cultural experience, the National Theater showcases captivating performances, blending romance and entertainment in a vibrant setting. Meanwhile, Estadio Nacional Rod Carew provides an exciting venue for sports events, fueling your adrenaline.

Adventure

Embark on the Honeycreeper Ridge Trail, a scenic hiking experience 40.2km from Panama City, where lush landscapes await. For thrill-seekers, Gatun Eco Adventures offers an exhilarating zipline course 46.7km away, surrounded by vibrant nature and adventure vibes that will leave you breathless.

Nightlife

In Panama City, experience vibrant nightlife in areas like Casco Viejo and the Avenida Balboa. Enjoy lively bars, trendy clubs, and rooftop lounges offering stunning skyline views. Dance the night away at venues like La Tana and Teatro Amador, where local DJs and live music create an unforgettable atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in Panama City

Panama City, located in Panamá Province, is ideal for family, city, and business-themed vacations. Visitors can explore various points of interest, including vibrant streets, event venues, and urban parks, all catering to those seeking cultural and family experiences. Don't miss the beautiful Panama City beaches for relaxation and fun. This dynamic city offers a perfect blend of urban excitement and natural beauty for every type of traveler.

  • Avenida Balboa: Stroll along this vibrant street that runs parallel to the coastline, offering stunning views of the Pacific Ocean and the Panama City skyline. Enjoy a variety of shops, restaurants, and parks that embody the city's lively atmosphere.
  • Panama Canal Railway: Experience a historic journey on this iconic railway, which connects the Atlantic and Pacific Oceans. The scenic ride through lush landscapes and alongside the famous Panama Canal provides a unique glimpse into the region's rich cultural heritage.
  • Metropolitan Nature Park: Escape the urban hustle at this expansive nature reserve, featuring diverse flora and fauna. Enjoy hiking trails that offer breathtaking views of the city and opportunities for birdwatching and picnicking in a serene environment.

Best time to go to Panama City

The best time to visit Panama City can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Panama City falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Panama City falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnySlightly HighSlightly High
February79.2°F (26.2°C)No RainMostly SunnyAverageAverage
March79.7°F (26.5°C)No RainMostly SunnyAverageSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageAverage
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudyAverageAverage
July79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudySlightly LowSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly LowSlightly High

Tips to save on your trip to Panama City

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Panama City.
  • Consider traveling during the off-peak season (typically September to November) for more affordable package holidays to Panama City.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Panama City Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
¥21,950
¥24,145 total
Sep 13 - Sep 14
includes taxes & fees
Hotel Riu Plaza Panama
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
¥29,247
¥32,172 total
Sep 13 - Sep 14
includes taxes & fees
9.2/10 Wonderful! (1,001 reviews)
"Nice hotel. Great location. Good breakfast. Our only complaint is about noise. The hotel has live music in the atrium from early in the morning until about 10 pm. Our room, along with many others, had windows facing into the atrium, and the noise from the music, and sometimes large tour groups at ..."

Reviewed on Aug 10, 2026

Central Hotel Panama Casco Viejo
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
¥31,252
¥34,377 total
Aug 29 - Aug 30
includes taxes & fees
8.4/10 Very Good! (1,657 reviews)
"Fantastic hotel great price. Has its own mall. Everything within walking distance. All employees spoke fantastic English. Nice tapas as well. Shame the pool was undergoing some renovations but these things happen. Would highly recommend"

Reviewed on Aug 13, 2026

Megapolis Hotel Panamá
See all 1,728 properties in Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Panama City attractions

A modern building facade with vertical reflective panels and the word "GUCCI" prominently displayed.
Photo by Fabiola Tile

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
Panama's premier shopping destination houses over 500 stores, from luxury brands like Gucci to popular retailers like Apple. Obtain the Panama Shopping Card at reception for exclusive discounts throughout the mall.
See properties
A city skyline with tall buildings along a waterfront.
Photo by Rob Gosse

Cinta Costera

9.2/10 (3,823 reviews)
This scenic 7 km waterfront promenade showcases Panama City's dramatic skyline against the Pacific Ocean. Stroll through gardens, cycle along dedicated paths, or sample fresh seafood at the nearby Mercado de Mariscos.
See properties
A marina with numerous boats, a bridge in the background, and lush green hills.

Amador Causeway

9.0/10 (1,902 reviews)
This man-made causeway connects Panama City to four islands using excavated material from the Panama Canal. Rent a bicycle to explore its entire length, stopping for waterfront dining with skyline views.
See properties
A nighttime cityscape with illuminated skyscrapers and a river reflecting the lights.

Avenida Balboa

8.8/10 (3,608 reviews)
Panama City's iconic waterfront boulevard offers spectacular views of the Pacific Ocean and skyline. Stroll along the Cinta Costera at sunset for a perfect blend of urban energy and coastal tranquility.
See properties
A historic stone tower amidst ruins, surrounded by grassy terrain.

Panama Viejo

9.2/10 (3,752 reviews)
Panama Viejo stands as the oldest European settlement on the Pacific coast of the Americas, founded in 1519. Wander among colonial ruins and climb the cathedral tower for a unique perspective on Panama's layered history.
See properties

Albrook Shopping Mall

8.6/10 (4,561 reviews)
One of Central America's largest shopping destinations, Albrook Mall features animal-themed corridors with matching statues. Explore 600+ stores, dine at diverse restaurants, or enjoy cinema and bowling.
See properties

Via Espana

8.4/10 (2,902 reviews)
Vía España pulses as Panama City's commercial backbone, lined with shops and diverse dining options. Explore this vibrant thoroughfare during late morning when the urban energy is at its peak.
See properties

El Dorado Mall

8.2/10 (1,337 reviews)
El Dorado Mall offers a blend of retail stores, dining options, and entertainment in Panama City. Browse electronic shops, enjoy Asian cuisine, or catch the latest films at the modern cinema complex.
See properties

What to do in Panama City

Panama City: Zip Line Experience Over The City & a Cocktail

Panama City: Zip Line Experience Over The City

¥6,384
per adult
96% of travellers recommend
Panama City: Zip Line Experience Over The City
Panama Canal: The Most Complete Monkey Island Experience

Panama Canal: The Most Complete Wildlife Experience

¥9,577
per adult
94% of travellers recommend
Panama Canal: The Most Complete Wildlife Experience
From Panama City: Monkey Islands Tour on Gatun Lake

From Panama City: Monkey Islands Tour on Gatun Lake

¥4,788
per adult
94% of travellers recommend
From Panama City: Monkey Islands Tour on Gatun Lake
See all activities in Panama City

Frequently asked questions

How much does a Panama City vacation package cost?
You can pick up a vacation package to this destination on Expedia. However, how much your vacation to Panama City costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Panama City?
You're likely to find lower rates and better availability in September, October and November. Take a look at our cheap Panama City vacation packages and you could get some great off-season discounts.
How many days is enough for Panama City?
Dedicate around 3 days for your Panama City vacation in order to discover everything that makes this destination special. Stroll around popular areas, including San Francisco and Campo Alegre. Then check out major sights such as Metropolitan Cathedral of Panama and National Theater. With a good itinerary, you can keep busy with room for some rest time too. Want to travel beyond Panama City? Consider squeezing in an excursion or two.
Is it worth booking a vacation package to Panama City?
Popular for its nature, nightlife and culture, a Panama City vacation is a hit with all types of travelers. Be sure to visit leading sights like Albrook Shopping Mall and Cinta Costera, and consider renting a car for day trips to explore even more.
How to find the best Panama City package deals?
Landing a cheap Panama City package deal is a cinch with Expedia. After you've entered your destination and travel dates under our "Packages" tab, set your budget range, add some filters and browse what's available. You can tweak your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most wallet-friendly Panama City package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Panama City vacation as a package?
You can enjoy significant savings on your Panama City getaway by booking a personalized vacation package. Click on the "Package" heading, then select your travel dates and destination to see the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Panama City?
Enjoy incredible discounts by booking your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for a spur-of-the-moment Panama City trip.
How to plan a trip to Panama City?
  1. Choose when to go: Check your schedule and get your bags packed. Your preferred time of year and the available activities will also help you decide when to visit Panama City.
  2. Plan your budget wisely: As well as the cost of your stay, you'll need to factor in other expenses too. These include food, flights and transportation. Also, put aside a little extra for unexpected costs that could arise during your trip to Panama City.
  3. Work out your trip length: Think about how long you want to spend exploring Panama City. Plan your itinerary so you can get to all the attractions and activities you're interested in at a leisurely pace.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a customized Panama City vacation package.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.