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Our top choices for Panama City luxury hotels

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (259)
"Great location!"
United States
Erik
The price is ¥53,500
¥58,850 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Hotel La Compañía Casco Antiguo

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (566)
"Amazing hotel , location , staff and amenities . Clean, elegant , great service. "
United States
Nicole
The price is ¥57,226
¥62,949 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Sofitel Legend Casco Viejo, Panama City

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1003)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is ¥49,946
¥54,940 total
includes taxes & fees
Jan 3 - Jan 4, 2026
JW Marriott Panama

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
4.0 star property
Veracruz
7.6 out of 10, Good, (1005)
"Food and drinks were amazing! "
Canada
Adrienne
The price is ¥62,784
¥62,784 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Dreams Playa Bonita Panama - All Inclusive

La Concordia Boutique Hotel

La Concordia Boutique Hotel
4.0 star property
Casco Viejo
9.6 out of 10, Exceptional, (194)
"Beautiful room Good location"
United States
Karla
The price is ¥46,684
¥51,353 total
includes taxes & fees
Jan 12 - Jan 13, 2026
La Concordia Boutique Hotel

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very Good, (1000)
"Great place and location, excellent food choices! "
United States
Francisco
The price is ¥37,063
¥40,770 total
includes taxes & fees
Jan 7 - Jan 8, 2026
The Westin Playa Bonita Panama

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (644)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ¥35,111
¥38,623 total
includes taxes & fees
Jan 25 - Jan 26, 2026
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1007)
"Nice hotel in the historic center, excellent location for sightseeing and walking around at night."
United States
Antonio
The price is ¥55,786
¥61,365 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Central Hotel Panama Casco Viejo

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1314)
"Clean convenient beautiful hotel. "
United States
Daniel
The price is ¥36,565
¥40,222 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Megapolis Hotel Panamá

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1001)
"I loved everything about my stay "
United States
Stephanie
The price is ¥34,536
¥37,990 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Waldorf Astoria Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Panama City Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 23 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best luxury accommodation in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Megapolis Hotel Panamá and W Panama are other upscale choices for your trip.
How many luxury hotels will I be able to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 23 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Panama City are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Crown Casino.
How can I get around Panama City?
It's easier to get around town in style when you know your options. You can walk to nearby metro stations including Iglesia del Carmen Station, Vía Argentina, and Santo Tomas Station. If you want to venture outside of the area, hop on a train at Panama City Passenger Station.

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