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Find hotels near Calle 50, Panama City from ¥6,871

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Our top choices for Calle 50 hotels

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Campo Alegre, 1.2 km from Calle 50
10.0 out of 10, Exceptional, (136)
"Great hotel fair price"
United States
Santiago
The price is ¥24,475
¥26,922 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hyatt Regency Panama City

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 1 km from Calle 50
9.6 out of 10, Exceptional, (1126)
"The room was clean and the location was great."
United States
Wendy
The price is ¥15,302
¥16,832 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Ramada Plaza by Wyndham Panama Punta Pacifica

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco, 0.4 km from Calle 50
9.0 out of 10, Wonderful, (1001)
"Staff was very helpful. Great location."
United States
John
The price is ¥14,506
¥15,957 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Courtyard by Marriott Panama Multiplaza Mall

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 0.7 km from Calle 50
9.0 out of 10, Wonderful, (4722)
"Awesome great place to stay "
United States
Herbert
The price is ¥19,121
¥21,033 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Hotel Riu Plaza Panama

Yoo Panama & Arts Tower

Yoo Panama & Arts Tower
3.0 star property
Bella Vista, 1.3 km from Calle 50
9.6 out of 10, Exceptional, (55)
"Ron was amazing and so was the property!"
United States
John
Yoo Panama & Arts Tower

Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1612)
"Friendly staff. "
United States
Thessely
The price is ¥8,627
¥9,490 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Principe Hotel and Suites

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
Punta Paitilla, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1000)
"I loved my stay! "
United States
Jenniffer Gonzalez De La
The price is ¥24,572
¥27,029 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Las Americas Golden Tower Panama

The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (1005)
"A nice hotel to stay great location"
United States
angela
The Executive Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Campo Alegre, 1.1 km from Calle 50
9.4 out of 10, Exceptional, (1000)
"Great staff, super accommodating. Best place to stay in Panama!"
United States
Sebastian
The price is ¥31,322
¥34,454 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Bristol Panama, a Registry Collection Hotel

Novotel Panama City

Novotel Panama City
4.0 star property
El Cangrejo, 1.1 km from Calle 50
9.2 out of 10, Wonderful, (1039)
"The hotel was very nice and the staff was great."
United States
Cena
The price is ¥17,144
¥18,858 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Novotel Panama City

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 1.3 km from Calle 50
9.4 out of 10, Exceptional, (2140)
"Great location of the hotel with a lovely breakfast and friendly staff"
United States
fouad
The price is ¥16,855
¥18,540 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Plaza Paitilla Inn Hotel

Gran Evenia Panama

Gran Evenia Panama
4.5 star property
El Cangrejo, 1 km from Calle 50
9.2 out of 10, Wonderful, (196)
"The property was conveniently located near shops, restaurants and casinos. The food at breakfast was good. Although the pancakes could be better. "
United States
Nicole
Gran Evenia Panama

Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG
4.0 star property
Campo Alegre, 0.7 km from Calle 50
8.8 out of 10, Excellent, (1001)
"Clean room , friendly staff "
United States
Junique
The price is ¥12,526
¥14,640 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Holiday Inn Panama Distrito Financiero by IHG

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Obarrio, 0.6 km from Calle 50
8.8 out of 10, Excellent, (1001)
"Everything was clean and the staff was very cooperative."
United States
Deangelo
The price is ¥24,826
¥27,309 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

MARINN PLACE Financial District

MARINN PLACE Financial District
3.5 star property
Campo Alegre, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (299)
"Second stay, very nice"
Canada
Xiaozhi
The price is ¥17,488
¥19,237 total
includes taxes & fees
Dec 30 - Dec 31
MARINN PLACE Financial District

Nomada Container Hotel Panama City

Nomada Container Hotel Panama City
3.0 star property
Obarrio, 0.5 km from Calle 50
8.8 out of 10, Excellent, (162)
"Great"
United States
Joel
The price is ¥10,624
¥11,686 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Nomada Container Hotel Panama City

Hostal Familiar Carmencita - Hostel

Hostal Familiar Carmencita - Hostel
2.0 star property
Bella Vista, 1.1 km from Calle 50
9.2 out of 10, Wonderful, (9)
"The manager was very nice. Close to some good restaurants."
United States
Brooke
Hostal Familiar Carmencita - Hostel

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
Punta Paitilla, 1 km from Calle 50
9.0 out of 10, Wonderful, (543)
"It's location is close to everything. "
United States
Sharon
The price is ¥25,153
¥27,668 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Residence Inn by Marriott Panama City

Hotel Milan

Hotel Milan
3.0 star property
El Cangrejo, 1.3 km from Calle 50
9.0 out of 10, Wonderful, (431)
"It was a very pleasant experience the hotel is located in a great neighborhood, staff were friendly and competent, secure property and parking, clean and decent accommodations, especially at the room price point. "
Canada
Roger
The price is ¥6,246
¥6,871 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hotel Milan

San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (56)
"Clean and walkable location"
United States
Tamera
The price is ¥19,392
¥25,235 total
includes taxes & fees
Jan 18 - Jan 19, 2026
San Francisco by Wynwood House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Calle 50 Hotel Reviews

Hotels near other Calle 50 attractions

Frequently asked questions

What's the area like around Calle 50?
Calle 50 is located in Panama City. This welcoming area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 461 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Calle 50?
Hotel Riu Plaza Panama is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and free breakfast. It's located just a short 0.5 mi (0.7 km) from Calle 50. Other good options close by include Las Americas Golden Tower Panama and Megapolis Hotel Panamá.
How many hotels will I be able to find near Calle 50?
Expedia has 461 hotels and other accommodations within a mile from Calle 50.
If I need to cancel the hotel reservation for my stay near Calle 50, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of your booking. Add dates, click "Search", then use the "fully refundable" filter to view the best deals available near Calle 50.
Where can I learn more about changing or cancelling my trip in the area near Calle 50?
To find more details about updating your stay near Calle 50 or cancelling it, go to https://www.expedia.com/service/.
What can I see and do near Calle 50?
You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo, and Colonial Religious Art Museum. Iglesia del Carmen, Panama Viejo, and Panama Canal Railway are notable landmarks to explore if you're in the area. You can catch a show at National Theater, Theater Circle, and Anita Villalaz Theater.
How can I get to Calle 50?
Local metro stations include Iglesia del Carmen Station and Vía Argentina. If you'd like to explore around the surrounding area, you may want a car rental for your journey.

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