Photo by PhotoJoy
Resorts & Hotels with Spas in Panama from ￥20,615
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Panama Resorts & Hotels with Spas
Our top choices for Panama hotels with a spa
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by MarriottBella Vista
8.8 out of 10, Excellent, (1,002 reviews)
- Luxurious spa retreat in the heart of Panama with 10 treatment rooms and pampering Ayurvedic services for a complete wellness journey.
The price is ￥26,608
￥29,268 total
includes taxes & fees
Jun 28 - Jun 29
8.6 out of 10, Excellent, (2,594 reviews)
The price is ￥21,937
￥25,195 total
includes taxes & fees
Jun 28 - Jun 29
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama CityJuan Diaz
9.6 out of 10, Exceptional, (703 reviews)
- Discover tranquility at this luxury spa oasis with 5 treatment rooms and a garden retreat for the ultimate wellness escape.
The price is ￥43,362
￥47,698 total
includes taxes & fees
Jul 2 - Jul 3
The price is ￥27,260
￥29,986 total
includes taxes & fees
Jun 27 - Jun 28
9.4 out of 10, Exceptional, (1,000 reviews)
- Immerse in luxurious tranquility at this Art Deco hotel with 6 treatment rooms and an outdoor pool for a rejuvenating retreat.
The price is ￥36,251
￥39,876 total
includes taxes & fees
Jul 18 - Jul 19
Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free MallBarrio Sur
8.2 out of 10, Very Good, (941 reviews)
- Rejuvenate at this waterfront hotel featuring couples spa treatments, an outdoor pool, and hot stone massages for a serene escape.
The price is ￥18,741
￥20,615 total
includes taxes & fees
Jul 5 - Jul 6
9.8 out of 10, Exceptional, (669 reviews)
- Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel.
The price is ￥48,632
￥53,495 total
includes taxes & fees
Jul 12 - Jul 13
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Panama Hotel Reviews
Hotel Riu Plaza Panama
10/10 Excellent
Explore a world of travel with Expedia
- Hostels in Santiago
- Resorts & Hotels with Spas in Panama City
- Resorts in Guna Yala
- Aparthotels in La Laguna
- Aparthotels in Los Angeles
- Lodges in San Blas Islands
- B&B in La Loma
- Resorts in Maria Chiquita
- Panama City Hotels
- Romantic Hotels in San Jose
- Business Hotels in Bugaba
- Luxury Hotels in Buena Vista
- Guest Houses in Herrera
- Resorts in Narganá
- Cheap Hotels in Boquete
- San Jose Hotels
- Resorts in Coco Key
- Cheap Hotels in Los Angeles
- Pet-Friendly Hotels in San Carlos
- Santa Clara Hotels
- Adults Only Resorts & in Panamá Province
- Historic Hotels in Boca Chica
- Beach Hotels in Boca Chica
- Cheap Hotels in Frances
- Lodges in La Laguna
- Ranches in Bocas del Toro Province
- Aparthotels in Panama City
- Cheap Hotels in Santa Catalina
- Cheap Hotels in Nata
- B&B in Sorá
- Resorts in San Blas Islands
- Luxury Hotels in Río Sereno
- Tocumen Hotels
- San Blas Islands Hotels
- Scuba Diving Hotels in Panama City
- Resorts in La Loma
- B&B in Narganá
- Family Hotels in Anton
- Panamá Province Hotels
- Villas in Colón
- Resorts in Los Angeles
- Hostels in Sorá
- Luxury Hotels in Los Angeles
- Guest Houses in Sorá
- Resorts in Boquete
- B&B in Bugába
- Cheap Hotels in Palenque
- Resorts in La Laguna
- Resorts in Buenaventura
- Luxury Hotels in Santa Catalina
- Los Angeles Hotels
- Resorts in Bugába
- Adults Only Resorts & in Panama City
- Luxury Hotels in Coco Key
- Guna Yala Hotels
- Beach Hotels in Bocas del Toro
- Hostels in San Blas Islands
- Resorts in San Juan Bautista
- Residences in Los Naranjos
- Beach Hotels in Bugaba
- Isla Grande Hotels
- Beach Hotels in La Arena
- Cheap Hotels in Guna Yala
- Santiago Hotels
- Hotels with a Pool in Panama City
- All-Inclusive Hotel Hotels in Bugaba
- Nata Hotels
- Villas in Los Angeles
- Adults Only Resorts & in Bocas del Toro Province
- Resorts in Isla Grande
- Aparthotels in Panamá Province
- Boquete Hotels
- Beach Hotels in Rio Hato
- Cheap Hotels in La Laguna
- Cheap Hotels in San Carlos
- Luxury Hotels in Panama City
- Resorts & Hotels with Spas in Bugaba
- Hostels in Nata
- Resorts in Bugaba
- Resorts in Rio Hato
- La Laguna Hotels
- All-Inclusive Hotel Hotels in Cambutal
- Beach Hotels in Panama City
- Ranches in Bugaba
- Cheap Hotels in Panama City
- Hostels in Bocas del Toro Province
- Luxury Hotels in Bugaba
- Shopping Hotels in Santa Clara
- Resorts in Bocas del Toro Province
- All-Inclusive Hotel Hotels in Rio Hato
- Capsule Hotels in Narganá
- Capsule Hotels in Coclé
- Sorá Hotels
- Hotels with Early Check-in in Panama City