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Compare 1,453 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Panama City hotels

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2202)
"I love how convenient it is for people to get to the hotel , the food was great , service was great too! "
The price is ¥16,789
¥18,468 total
includes taxes & fees
Sep 25 - Sep 26
Crowne Plaza Panama Airport by IHG

Waymore Hotel Spa & Casino

4.0 star property
9.2 out of 10, Wonderful, (442)
"Thank you really like staying there first time"
The price is ¥11,927
¥13,120 total
includes taxes & fees
Aug 29 - Aug 30
Waymore Hotel Spa & Casino

Arcadia Condo Suites

2.5 star property
9.2 out of 10, Wonderful, (57)
"its a very nice place "
The price is ¥8,350
¥15,989 total
includes taxes & fees
Aug 29 - Aug 30
Arcadia Condo Suites

Summit Rainforest & Golf Resort

4.0 star property
8.4 out of 10, Very Good, (1002)
"Lovely hotel set next to a rainforest. Loved the tour of the butterfly garden and nature trail. Clean premises and pleasant staff. "
The price is ¥10,788
¥11,867 total
includes taxes & fees
Sep 7 - Sep 8
Summit Rainforest & Golf Resort

Radisson Hotel Panama Canal

4.5 star property
8.4 out of 10, Very Good, (1001)
"Very nice hotel!"
The price is ¥12,643
¥13,907 total
includes taxes & fees
Sep 27 - Sep 28
Radisson Hotel Panama Canal

Courtyard by Marriott Panama Metromall

4.0 star property
8.8 out of 10, Excellent, (1008)
"Lovely hotel in a great and safe location"
The price is ¥14,447
¥15,891 total
includes taxes & fees
Sep 6 - Sep 7
Courtyard by Marriott Panama Metromall

Hotel Milan

3.0 star property
9.0 out of 10, Wonderful, (385)
"I enjoyed my stay "
The price is ¥5,891
¥6,480 total
includes taxes & fees
Sep 9 - Sep 10
Hotel Milan

Principe Hotel and Suites

3.0 star property
9.0 out of 10, Wonderful, (1444)
"Perfect stay as always!!! "
The price is ¥8,615
¥9,477 total
includes taxes & fees
Aug 29 - Aug 30
Principe Hotel and Suites

Hyatt Regency Panama City

4.5 star property
10.0 out of 10, Exceptional, (62)
"Friendly staff.. great food and in a convenient location to allow pick up for tours"
The price is ¥24,506
¥26,957 total
includes taxes & fees
Sep 14 - Sep 15
Hyatt Regency Panama City

Riande Aeropuerto Hotel & Casino

4.0 star property
8.4 out of 10, Very Good, (1891)
"Lovely setting with quick shuttle service to the airport!"
The price is ¥21,364
¥23,500 total
includes taxes & fees
Sep 24 - Sep 25
Riande Aeropuerto Hotel & Casino

The Beach House

3.0 star property
8.4 out of 10, Very Good, (394)
"This was a great stay! We enjoyed the view from our balcony, I mean, on one side Panama City and on the other side Amador and the Pacific. We even enjoyed watching raccoons play on the surf. The breakfast was ok. But Nextdoor was the great Ranchito Restaurant which served like the best sangria ever. I had a seafood soup which was very tasty. So I am definitely going back on my next stay."
The Beach House

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (936)
"A great stay. "
The price is ¥19,749
¥21,724 total
includes taxes & fees
Sep 12 - Sep 13
Sheraton Grand Panama

Panama House Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (171)
"Was amazing the host and the people there was super friendly and welcoming. Also has amazing local food spots within walking distance."
The price is ¥6,084
¥6,692 total
includes taxes & fees
Sep 7 - Sep 8
Panama House Bed & Breakfast

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1297)
"Easy to reach and valet parking"
The price is ¥13,994
¥15,393 total
includes taxes & fees
Aug 29 - Aug 30
Decapolis Hotel Panama City

Renaissance Panama City Hotel

5.0 star property
8.8 out of 10, Excellent, (49)
"Staff very friendly and accommodating. We extended our stay at this hotel because of the property and the staff. "
The price is ¥15,169
¥16,686 total
includes taxes & fees
Sep 20 - Sep 21
Renaissance Panama City Hotel

American Trade Hotel

4.5 star property
9.4 out of 10, Exceptional, (553)
"Beautiful property and friendly staff!"
The price is ¥37,642
¥41,406 total
includes taxes & fees
Sep 9 - Sep 10
American Trade Hotel

Casa Orquídea

2.0 star property
The price is ¥9,469
¥10,416 total
includes taxes & fees
Sep 10 - Sep 11
Casa Orquídea

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (1049)
"Had a wonderful stay the staff is very friendly and attentive "
The price is ¥18,438
¥20,282 total
includes taxes & fees
Sep 21 - Sep 22
Megapolis Hotel Panamá

La Residence Panamá

2.5 star property
The price is ¥19,145
¥21,060 total
includes taxes & fees
Sep 10 - Sep 11
La Residence Panamá

Hotel San Felipe

4.0 star property
9.4 out of 10, Exceptional, (186)
"Friendly staff! Spacious rooms. "
The price is ¥18,556
¥20,412 total
includes taxes & fees
Sep 9 - Sep 10
Hotel San Felipe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
Learn more about Panama City

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

1 out of top 10 points of interest in this area

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

San Francisco

1 out of top 10 points of interest in this area

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Stay near popular Panama City attractions

Learn more about Panama City

Experience Panama City: its casinos, cafes, and more!

Top Panama City Hotel Reviews

More cheap stays in Panama City

More cheap stays in Panama City

Hotels in Panama City with star-rating

Hotels in Panama City with star-rating

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's the best place to stay in Panama City?

Hyatt Regency Panama City is a favorite property for Expedia customers. This hotel is a short 4-minute walk from Via Espana, and it offers a full-service spa and 2 bars. Reviews from our site also recommend Sofitel Legend Casco Viejo, Panama City and Hotel La Compania, in the Unbound Collection by Hyatt as top options for your stay. See all available top hotels, or vacation rentals in Panama City.

Casco Viejo is a top neighborhood that travelers like for its bars and historic landmarks.

What's the top vacation rental that Panama City has to offer?

Panama View House – A Hilltop Retreat with Stunning Canal Views: This highly rated vacation home rental in Panama City has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Some other homes for rent in Panama City include Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces and Breathtaking Views Mansion w/King Beds. See all vacation rentals in Panama City.

If I need to cancel my hotel reservation in Panama City, will I receive a refund?

Yes, most hotel reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Panama City.

Where can I learn more about changing or cancelling my trip to Panama City?

To access more information about rescheduling or cancelling your trip to Panama City, go to https://www.expedia.com/service/.

What's the best budget-friendly hotel in Panama City?

Based on reviews, Hotel Riu Plaza Panama is a popular hotel for our travelers who want a more economical choice, and features free buffet breakfast and free WiFi. Other choices to stay on the cheap include Principe Hotel and Suites and The Executive Hotel. View all budget hotels in Panama City.

Where is the best hotel for a stay in Casco Viejo?

With 20 hotels and other accommodations to choose from in this neighborhood, you should find the perfect place for your trip. Based on Expedia customer reviews, American Trade Hotel is the highest ranked property in Casco Viejo. This 4.5-star hotel offers a restaurant and an outdoor pool. It is located a short 3-minute walk from Metropolitan Cathedral of Panama. Other top choices in the neighborhood include Magnolia Inn and Tantalo Hotel / Kitchen / Roofbar.

What's the best place to stay for a family trip to Panama City?

JW Marriott Panama is a hotel with 4 outdoor pools and 3 restaurants, and it's a top choice on Expedia for families. Other choices for your kid-friendly vacation include Sheraton Grand Panama and Marriott Panama Hotel. Attractions like Biomuseo and Summit Botanical Gardens & Zoo are also fun for kids of all ages. Find more child-friendly accommodations in Panama City.

What's the best LGBTQ-friendly hotel in Panama City?

Hotel Riu Plaza Panama is a top LGBTQ-friendly hotel, and features 3 restaurants and free WiFi. JW Marriott Panama and AC Hotel by Marriott Panama City are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Panama City.

What's the best pet-friendly place to stay in Panama City?

JW Marriott Panama is a top hotel for people traveling with their pets, and offers 3 restaurants and 4 outdoor pools for its human guests. Other good options for you and your pet's trip include Sheraton Grand Panama and Marriott Panama Hotel. See more pet-friendly hotel accommodations in Panama City.

What's the best place to stay close to Albrook Shopping Mall?

Wyndham Panama Albrook Mall Hotel & Convention Center is one of the top choices for your stay based on our traveler data, and this 4-star hotel offers 2 restaurants and 2 bars. It's located just a short 0.4 mi (0.6 km) from Albrook Shopping Mall. Another good option is GM Lodge, located just 0.3 mi (0.5 km) away.

What about the best place to stay close to Multiplaza Pacific Mall?

One of the top choices for your stay is Courtyard by Marriott Panama Multiplaza Mall, located next to Multiplaza Pacific Mall, and this 4-star hotel offers a restaurant and an outdoor pool. Hotel Riu Plaza Panama and JW Marriott Panama are other good choices nearby.

What's the best accommodation for a beach vacation in Panama City?

Akwadup Lodge is a top beachfront lodge with a restaurant, and it's located close to Veracruz Beach. See more stays near the beach in Panama City.

What's the best luxury accommodation in Panama City?

Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Megapolis Hotel Panamá and JW Marriott Panama are two other upscale options for your trip. Find more luxury hotels in Panama City.

What's the best boutique hotel in Panama City?

De Ville Hotel is a favorite hotel with our travelers looking for a stylish accommodation, and features 33 guestrooms, free breakfast, and free valet parking. If you'd prefer to stay at a boutique hotel, you can also take a look at Gatto Blanco Party Hotel. See all boutique hotels in Panama City.

What's the best accommodation to visit the local casinos in Panama City?

Megapolis Hotel Panamá is a top hotel featuring a casino and free stocked minibars. Other good options to try your luck include Decapolis Hotel Panama City and Hilton Panama. See more casino hotels in Panama City.

Where is the best area of Panama City for tourists?

Casco Viejo is one of the best areas of the city for sightseeing with 15 places to visit including Metropolitan Cathedral of Panama, Interoceanic Canal Museum, and Casco viejo panama basilica.

What are some accommodations with pools in Panama City?

JW Marriott Panama is a top hotel with 4 outdoor pools, a children's pool, and 3 restaurants. A couple of other options that feature an onsite pool include Sheraton Grand Panama and Marriott Panama Hotel. View all hotels with pools in Panama City.

What is the best spa hotel in Panama City?

Waymore Hotel Spa & Casino is a top spa hotel featuring a bar, an outdoor pool, and a restaurant. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. Other popular spa hotels in Panama City include Megapolis Hotel Panamá and Sheraton Grand Panama. See all spa hotels in Panama City.

What is the best hotel near Tocumen International Airport (PTY)?

Crowne Plaza Panama Airport is a popular 4-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.4 km) from Tocumen Intl. Airport. Other good options within close proximity to the airport include Riande Aeropuerto Hotel & Casino and Express Inn Panama International Airport Hostel.

How is it to stay in Panama City?

Travelers to Panama City give high marks for the shopping, casinos, and top-notch restaurants. Tourists who journey to this scenic city can discover its cafes, bars, and local tours. A top sight in the city is Albrook Shopping Mall. In Panama City, there are 1346 hotels and other accommodations to choose from. Find out more about Panama City.

What should I do while I'm visiting Panama City?

Cultural venues include National Theater, Interoceanic Canal Museum, and Biomuseo. Landmarks like Iglesia del Carmen, Calle 50, and Panama Canal Railway might be worth a visit. Natural beauty is on display at Cinta Costera, Miraflores Locks, and Metropolitan Nature Park. Check out what more to see and do in Expedia's Panama City guide.

How can I get around Panama City?

You can walk to nearby metro stations including Iglesia del Carmen Station, Vía Argentina, and Santo Tomas Station. If you want to explore the larger area, hop aboard a train at Panama City Passenger Station. If you want to venture out around the area, you may want a rental car in Panama City for your journey.

What's the weather like in Panama City?

The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Panama City are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.