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Compare 1,445 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4154)
"I had a great stay there"
The price is ¥16,934
¥18,627 total
includes taxes & fees
Aug 25 - Aug 26
Hotel Riu Plaza Panama

Waymore Hotel Spa & Casino

4.0 star property
9.2 out of 10, Wonderful, (409)
"Great hotel for the price."
The price is ¥11,926
¥13,119 total
includes taxes & fees
Aug 16 - Aug 17
Waymore Hotel Spa & Casino

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (1016)
"Lovely hotel "
The price is ¥18,483
¥20,331 total
includes taxes & fees
Aug 29 - Aug 30
Megapolis Hotel Panamá

Hospedium Princess Hotel Panama

3.5 star property
7.6 out of 10, Good, (585)
"Good option and transport access"
The price is ¥6,388
¥7,027 total
includes taxes & fees
Aug 17 - Aug 18
Hospedium Princess Hotel Panama

TRYP by Wyndham Panamá Centro

3.5 star property
9.0 out of 10, Wonderful, (1002)
"location was amazing and very comfortable for the price"
The price is ¥12,722
¥13,994 total
includes taxes & fees
Aug 24 - Aug 25
TRYP by Wyndham Panamá Centro

Principe Hotel and Suites

3.0 star property
9.0 out of 10, Wonderful, (1433)
"Good to stay, everything around the hotel"
The price is ¥8,614
¥9,475 total
includes taxes & fees
Aug 17 - Aug 18
Principe Hotel and Suites

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (970)
"The hotel is beautiful and in perfect location. On site staff was very friendly and helpful. Would definitely stay here again."
The price is ¥26,947
¥29,642 total
includes taxes & fees
Aug 17 - Aug 18
Central Hotel Panama Casco Viejo

Hyatt Regency Panama City

4.5 star property
10.0 out of 10, Exceptional, (53)
"Friendly staff.. great food and in a convenient location to allow pick up for tours"
The price is ¥22,347
¥24,582 total
includes taxes & fees
Sep 14 - Sep 15
Hyatt Regency Panama City

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2097)
"Wonderful activities during weekends! Great place to stay! "
The price is ¥23,282
¥25,610 total
includes taxes & fees
Aug 17 - Aug 18
Plaza Paitilla Inn Hotel

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1001)
"Always an exceptional stay. "
The price is ¥32,417
¥35,659 total
includes taxes & fees
Aug 30 - Aug 31
JW Marriott Panama

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1282)
"Free internet, breakfast options nice and tasty"
The price is ¥13,992
¥15,391 total
includes taxes & fees
Aug 22 - Aug 23
Decapolis Hotel Panama City

Novotel Panama City

4.0 star property
9.0 out of 10, Wonderful, (1000)
"The best hotel"
The price is ¥14,180
¥15,598 total
includes taxes & fees
Aug 24 - Aug 25
Novotel Panama City

Hotel Coral Suites

3.5 star property
9.0 out of 10, Wonderful, (1000)
"Nice Hotel "
The price is ¥10,204
¥11,224 total
includes taxes & fees
Aug 16 - Aug 17
Hotel Coral Suites

Holiday Inn Panama Distrito Financiero by IHG

4.0 star property
8.8 out of 10, Excellent, (1000)
"Comfortable bed,quiet room, good food"
The price is ¥12,958
¥15,063 total
includes taxes & fees
Aug 30 - Aug 31
Holiday Inn Panama Distrito Financiero by IHG

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1000)
"The food was very good at the hotel. Several options to choose from at the hotel. "
The price is ¥30,313
¥33,344 total
includes taxes & fees
Aug 17 - Aug 18
Hilton Panama

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4.0 star property
7.8 out of 10, Good, (1002)
"The staff was very nice and helpful the hotel very modern and clean. We enjoyed our stay very much."
The price is ¥11,235
¥12,359 total
includes taxes & fees
Aug 18 - Aug 19
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Las Americas Golden Tower Panama

4.0 star property
8.8 out of 10, Excellent, (1002)
"amazing hotel great staff "
The price is ¥21,347
¥23,481 total
includes taxes & fees
Sep 6 - Sep 7
Las Americas Golden Tower Panama

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1000)
"We had an amazing time, great hotel and great breakfast. "
The price is ¥29,375
¥32,313 total
includes taxes & fees
Sep 13 - Sep 14
Bristol Panama, a Registry Collection Hotel

Ramada Plaza By Wyndham Panama Punta Pacífica

4.0 star property
9.6 out of 10, Exceptional, (1008)
"Great stay, breakfast was excellent! Excellent location for touring Panama City, easy acess to bus stops and Metro."
The price is ¥16,583
¥18,241 total
includes taxes & fees
Sep 13 - Sep 14
Ramada Plaza By Wyndham Panama Punta Pacífica

Marriott Panama Hotel

4.0 star property
9.0 out of 10, Wonderful, (1004)
"Excellent location, staff were pleasant and professional "
The price is ¥19,768
¥21,746 total
includes taxes & fees
Aug 31 - Sep 1
Marriott Panama Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
Learn more about Panama City
Casco Viejo map

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Bella Vista map

Bella Vista

1 out of top 10 points of interest in this area

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo map

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Punta Paitilla map

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

San Francisco map

San Francisco

1 out of top 10 points of interest in this area

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Stay near popular Panama City attractions

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

Best guest reviews of Panama City

Top Panama City Hotel Reviews

Frequently asked questions

What's the best place to stay in Panama City?

Hyatt Regency Panama City is a favorite property for Expedia customers. This hotel is a short 4-minute walk from Via Espana, and it offers a full-service spa and 2 bars. Reviews from our site also recommend Sofitel Legend Casco Viejo, Panama City and Hotel La Compania, in the Unbound Collection by Hyatt as top options for your stay. See all available top hotels, or vacation rentals in Panama City.

Casco Viejo is a top neighborhood that travelers like for its bars and historic landmarks.

What's the top vacation rental that Panama City has to offer?

Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces: This highly rated vacation home rental in Panama City offers a balcony, a selection of games, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 6 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. Some other homes for rent in Panama City include Charming Maison 4Bdr + 4Bth in Historic Center of Casco Viejo and Panama View House – A Hilltop Retreat with Stunning Canal Views. See all vacation rentals in Panama City.

If I need to cancel my hotel reservation in Panama City, will I receive a refund?

Yes, most hotel reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Panama City.

Where can I learn more about changing or cancelling my trip to Panama City?

To access more information about rescheduling or cancelling your trip to Panama City, go to https://www.expedia.com/service/.

What's the best budget-friendly hotel in Panama City?

Based on reviews, Hotel Riu Plaza Panama is a popular hotel for our travelers who want a more economical choice, and features free buffet breakfast and free WiFi. Other choices to stay on the cheap include Principe Hotel and Suites and The Executive Hotel. View all budget hotels in Panama City.

Where is the best hotel for a stay in Casco Viejo?

With 20 hotels and other accommodations to choose from in this neighborhood, you should find the perfect place for your trip. Based on Expedia customer reviews, American Trade Hotel is the highest ranked property in Casco Viejo. This 4.5-star hotel offers a restaurant and an outdoor pool. It is located a short 3-minute walk from Metropolitan Cathedral of Panama. Other top choices in the neighborhood include Magnolia Inn and Tantalo Hotel / Kitchen / Roofbar.

What's the best place to stay for a family trip to Panama City?

JW Marriott Panama is a hotel with 4 outdoor pools and 3 restaurants, and it's a top choice on Expedia for families. Other choices for your kid-friendly vacation include Sheraton Grand Panama and W Panama. Attractions like Biomuseo and Summit Botanical Gardens & Zoo are also fun for kids of all ages. Find more child-friendly accommodations in Panama City.

What's the best hotel for a romantic getaway to Panama City?

Megapolis Hotel Panamá is a favorite hotel for couples, and features a full-service spa and 2 restaurants. Other good choices for your romantic getaway include Decapolis Hotel Panama City and JW Marriott Panama. See all romantic hotels in Panama City.

What's the best LGBTQ-friendly hotel in Panama City?

Hotel Riu Plaza Panama is a top LGBTQ-friendly hotel, and features 3 restaurants and free WiFi. JW Marriott Panama and AC Hotel by Marriott Panama City are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Panama City.

What's the best pet-friendly place to stay in Panama City?

JW Marriott Panama is a top hotel for people traveling with their pets, and offers 3 restaurants and 4 outdoor pools for its human guests. Other good options for you and your pet's trip include Sheraton Grand Panama and W Panama. See more pet-friendly hotel accommodations in Panama City.

What's the best place to stay close to Albrook Shopping Mall?

Wyndham Panama Albrook Mall Hotel & Convention Center is one of the top choices for your stay based on our traveler data, and this 4-star hotel offers 2 restaurants and 2 bars. It's located just a short 0.4 mi (0.6 km) from Albrook Shopping Mall. Another good option is GM Lodge, located just 0.3 mi (0.5 km) away.

What about the best place to stay close to Multiplaza Pacific Mall?

One of the top choices for your stay is Courtyard by Marriott Panama Multiplaza Mall, located next to Multiplaza Pacific Mall, and this 4-star hotel offers a restaurant and an outdoor pool. Hotel Riu Plaza Panama and JW Marriott Panama are other good choices nearby.

What's the best accommodation for a beach vacation in Panama City?

Akwadup Lodge is a top beachfront lodge with a restaurant, and it's located close to Veracruz Beach. See more stays near the beach in Panama City.

What's the best luxury accommodation in Panama City?

Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. JW Marriott Panama and Megapolis Hotel Panamá are two other upscale options for your trip. Find more luxury hotels in Panama City.

What's the best boutique hotel in Panama City?

De Ville Hotel is a favorite hotel with our travelers looking for a stylish accommodation, and features 33 guestrooms, free breakfast, and free valet parking. If you'd prefer to stay at a boutique hotel, you can also take a look at Gatto Blanco Party Hotel. See all boutique hotels in Panama City.

What's the best accommodation to visit the local casinos in Panama City?

Megapolis Hotel Panamá is a top hotel featuring a casino and free stocked minibars. Other good options to try your luck include Decapolis Hotel Panama City and Renaissance Panama City Hotel . See more casino hotels in Panama City.

Where is the best area of Panama City for tourists?

Casco Viejo is one of the best areas of the city for sightseeing with 15 places to visit including Metropolitan Cathedral of Panama, Interoceanic Canal Museum, and Casco viejo panama basilica.

What are some accommodations with pools in Panama City?

JW Marriott Panama is a top hotel with 4 outdoor pools, a children's pool, and 3 restaurants. A couple of other options that feature an onsite pool include Sheraton Grand Panama and Marriott Panama Hotel. View all hotels with pools in Panama City.

What is the best spa hotel in Panama City?

Waymore Hotel Spa & Casino is a top spa hotel featuring a bar, an outdoor pool, and a restaurant. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. Other popular spa hotels in Panama City include Megapolis Hotel Panamá and Sheraton Grand Panama. See all spa hotels in Panama City.

What is the best hotel near Tocumen International Airport (PTY)?

Crowne Plaza Panama Airport is a popular 4-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.4 km) from Tocumen Intl. Airport. Other good options within close proximity to the airport include Riande Aeropuerto Hotel & Casino and Express Inn Panama International Airport Hostel.

How is it to stay in Panama City?

Travelers to Panama City give high marks for the shopping, casinos, and top-notch restaurants. Tourists who journey to this scenic city can discover its cafes, bars, and local tours. A top sight in the city is Albrook Shopping Mall. In Panama City, there are 1331 hotels and other accommodations to choose from. Find out more about Panama City.

What should I do while I'm visiting Panama City?

Cultural venues include National Theater, Interoceanic Canal Museum, and Biomuseo. Landmarks like Iglesia del Carmen, Calle 50, and Metropolitan Cathedral of Panama might be worth a visit. Natural beauty is on display at Cinta Costera, Miraflores Locks, and Metropolitan Nature Park. Check out what more to see and do in Expedia's Panama City guide.

How can I get around Panama City?

You can walk to nearby metro stations including Iglesia del Carmen Station, Vía Argentina, and Santo Tomas Station. If you want to explore the larger area, hop aboard a train at Panama City Passenger Station. If you want to venture out around the area, you may want a rental car in Panama City for your journey.

What's the weather like in Panama City?

The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Panama City are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.