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Check availability on Panama City Luxury Hotels

Tonight
Dec 3 - Dec 4
Tomorrow
Dec 4 - Dec 5
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Top Panama City Luxury Hotels

4 outdoor pools, free cabanas, pool umbrellas
JW Marriott Panama

JW Marriott Panama

5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1015)
"Spotless, friendly and great food. Great pools a restaurants. "
Canada
David
The price is ￥36,941
￥40,635 total
includes taxes & fees
Dec 15 - Dec 16
JW Marriott Panama
Couples treatment rooms, sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1010)
"Love this hotel. Busy area, but hotel and restaurant make up for it."
United States
Allen
The price is ￥26,932
￥29,625 total
includes taxes & fees
Dec 6 - Dec 7
Bristol Panama, a Registry Collection Hotel
View from property
Waldorf Astoria Panama

Waldorf Astoria Panama

5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1011)
"I loved everything about my stay "
United States
Stephanie
The price is ￥27,973
￥30,770 total
includes taxes & fees
Dec 15 - Dec 16
Waldorf Astoria Panama
Front of property - evening/night
American Trade Hotel

American Trade Hotel

4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (600)
"Excellent service and great rooms on a beautiful and historical building"
Canada
Manuel
The price is ￥45,423
￥49,965 total
includes taxes & fees
Jan 4 - Jan 5, 2026
American Trade Hotel
Meeting facility
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1006)
"Clean room nice location "
United States
daniel
The price is ￥24,767
￥27,244 total
includes taxes & fees
Dec 6 - Dec 7
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Outdoor pool
Hilton Panama

Hilton Panama

5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1006)
"Great place to stay."
United States
Salvador
The price is ￥28,997
￥31,897 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hilton Panama
View from property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

5.0 star property
San Francisco
8.4 out of 10, Very Good, (1001)
"Great stay! Very safe!"
United States
MARVIN
Megapolis Hotel Panamá
Outdoor pool
Manrey Boutique Hotel

Manrey Boutique Hotel

3.5 star property
Panama City
7.6 out of 10, Good, (255)
"Hotel was closed when we arrived. Had not told us about the closure so we had to scramble to find another hotel"
United States
Anonymous traveler
Manrey Boutique Hotel
View from property
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1032)
"Wonderful stay!"
United States
Martha
The price is ￥23,803
￥26,183 total
includes taxes & fees
Dec 17 - Dec 18
Las Americas Golden Tower Panama
Terrace/patio
Marriott Panama Hotel

Marriott Panama Hotel

4.0 star property
Panama City
9.0 out of 10, Wonderful, (1017)
"Great breakfast "
United States
Amina
The price is ￥22,080
￥24,289 total
includes taxes & fees
Dec 7 - Dec 8
Marriott Panama Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

JW Marriott Panama

JW Marriott Panama

10/10 Excellent
"Staff was excellent, very nice room , amenities were great, location was perfect "
Robert 4-night trip
Posted 2 days ago
JW Marriott Panama

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Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 23 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best luxury accommodation in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Megapolis Hotel Panamá and W Panama are other upscale choices for your trip.
How many luxury hotels will I be able to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 23 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Panama City are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Crown Casino.
How can I get around Panama City?
It's easier to get around town in style when you know your options. You can walk to nearby metro stations including Iglesia del Carmen Station, Vía Argentina, and Santo Tomas Station. If you want to venture outside of the area, hop on a train at Panama City Passenger Station.