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Our top choices for Panama City luxury hotels

Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down comforters, pillowtop beds, minibar
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (555)
"Great hotel and location "
United Kingdom
Russell
The price is ￥58,076
￥63,884 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Sofitel Legend Casco Viejo, Panama City
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (258)
"Great location!"
United States
Erik
The price is ￥51,518
￥56,670 total
includes taxes & fees
Dec 20 - Dec 21
Hotel La Compañía Casco Antiguo
4 outdoor pools, free cabanas, pool umbrellas
JW Marriott Panama

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1004)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is ￥40,526
￥44,578 total
includes taxes & fees
Jan 4 - Jan 5, 2026
JW Marriott Panama
View from property
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (638)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ￥36,109
￥39,720 total
includes taxes & fees
Dec 14 - Dec 15
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Breakfast, lunch served; local and international cuisine, garden views
American Trade Hotel

American Trade Hotel

American Trade Hotel
4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (603)
"Excellent service and great rooms on a beautiful and historical building"
Canada
Manuel
The price is ￥45,341
￥49,875 total
includes taxes & fees
Jan 13 - Jan 14, 2026
American Trade Hotel
Front of property
La Concordia Boutique Hotel

La Concordia Boutique Hotel

La Concordia Boutique Hotel
4.0 star property
Casco Viejo
9.6 out of 10, Exceptional, (194)
"Beautiful room Good location"
United States
Karla
The price is ￥35,070
￥38,577 total
includes taxes & fees
Dec 15 - Dec 16
La Concordia Boutique Hotel
4 outdoor pools, open 8:00 AM to 8:00 PM, free cabanas, sun loungers
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
4.0 star property
Veracruz
7.6 out of 10, Good, (1001)
"Everything was great especially the view and food"
United States
Leroy
The price is ￥44,159
￥44,159 total
includes taxes & fees
Dec 16 - Dec 17
Dreams Playa Bonita Panama - All Inclusive
3 outdoor pools, pool umbrellas, sun loungers
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very Good, (1002)
"Our stay was very nice, the service the hotel provides is wonderful, I highly recommend it"
United States
Mayra Alexandra Montes
The price is ￥30,943
￥34,037 total
includes taxes & fees
Dec 16 - Dec 17
The Westin Playa Bonita Panama
Front of property
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (1003)
"Excellent hotel , good breakfast, great location, would highly recommend "
United States
Glen
The price is ￥31,060
￥34,166 total
includes taxes & fees
Dec 16 - Dec 17
Central Hotel Panama Casco Viejo
2 restaurants, local cuisine
W Panama

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1002)
"It is a hotel with very comfortable and nicely designed rooms in the heart of Panama City. The hotel staff is efficient, attentive and friendly."
United States
SVETLANA
The price is ￥33,702
￥37,072 total
includes taxes & fees
Jan 12 - Jan 13, 2026
W Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Panama City Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Everything was amazing"
shalena 7-night trip
Posted 1 day ago
Hotel Riu Plaza Panama

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Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 23 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best luxury accommodation in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Megapolis Hotel Panamá and W Panama are other upscale choices for your trip.
How many luxury hotels will I be able to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 23 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Panama City are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Crown Casino.
How can I get around Panama City?
It's easier to get around town in style when you know your options. You can walk to nearby metro stations including Iglesia del Carmen Station, Vía Argentina, and Santo Tomas Station. If you want to venture outside of the area, hop on a train at Panama City Passenger Station.