Find 4 Star Hotels in Panama City from ¥6,138
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Panama City 4 Star Hotels
Compare Panama City 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
8.4 out of 10, Very Good, (2150)
The price is ¥18,392
¥20,231 total
includes taxes & fees
Aug 3 - Aug 4

Sheraton Grand Panama
Sheraton Grand Panama
8.6 out of 10, Excellent, (902)
The price is ¥18,555
¥20,411 total
includes taxes & fees
Jul 25 - Jul 26

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
7.8 out of 10, Good, (1005)
The price is ¥14,951
¥16,446 total
includes taxes & fees
Aug 11 - Aug 12

Waymore Hotel Spa & Casino
Waymore Hotel Spa & Casino
9.0 out of 10, Wonderful, (346)
The price is ¥11,880
¥13,068 total
includes taxes & fees
Jul 20 - Jul 21

Ramada Plaza By Wyndham Panama Punta Pacífica
Ramada Plaza By Wyndham Panama Punta Pacífica
9.6 out of 10, Exceptional, (1002)
The price is ¥15,573
¥17,130 total
includes taxes & fees
Jul 27 - Jul 28

Studio Coliving
Studio Coliving
8.0 out of 10, Very Good, (409)
The price is ¥6,138
¥6,752 total
includes taxes & fees
Jul 20 - Jul 21

Novotel Panama City
Novotel Panama City
9.0 out of 10, Wonderful, (1002)
The price is ¥14,016
¥15,418 total
includes taxes & fees
Aug 3 - Aug 4

Megapolis Hotel Panamá
Megapolis Hotel Panamá
8.4 out of 10, Very Good, (957)
The price is ¥18,842
¥20,726 total
includes taxes & fees
Jul 20 - Jul 21
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama City.

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
The price is ¥19,134 per night from Aug 3 to Aug 4
¥19,134
¥21,047 total
Aug 3 - Aug 4
includes taxes & fees
9/10 Wonderful! (4,091 reviews)
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Panama City
Experience Panama City: its casinos, cafes, and more!

Top Panama City Hotel Reviews

Waymore Hotel Spa & Casino
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
More Hotel Options in Panama City
- Adults Only Resorts & Hotels in Panama City
- All-inclusive Hotel in Panama City
- Beach Hotels in Panama City
- Boutique Hotels in Panama City
- Casinos in Panama City
- Cheap Hotels in Panama City
- Gay friendly Hotels in Panama City
- Historic Hotels in Panama City
- Hotels with Early Check-in in Panama City
- Hotels with a Pool in Panama City
- Luxury Hotels in Panama City
- Resorts & Hotels with Spas in Panama City
- Winery Hotels in Panama City
More Accommodation Types in Panama City
Explore more hotels
- Decapolis Hotel Panama City
- Studio Coliving
- Waldorf Astoria Panama
- W Panama
- Sofitel Legend Casco Viejo, Panama City
- TRYP by Wyndham Panamá Centro
- Las Americas Golden Tower Panama
- The Executive Hotel
- Marriott Panama Hotel
- Plaza Paitilla Inn Hotel
- Hotel Ojos del Rio
- Residence Inn by Marriott Panama City
- Hyatt Regency Panama City
- Courtyard by Marriott Panama Multiplaza Mall
- Hilton Panama
Expedia's Latest Trends
Hotels
- Agora Kyoto Karasuma
- Hotels near Onjuku Beach
- Hotels near Takeshita Station
- Ryokan KANADE
- Chateraise Gateaux Kingdom Sapporo Hotel and Spa Resort
- Capsule Hotels Sendai
- Smile Hotel Okinawa Naha
- Hotels in Hongdae
- Grande Centre Point Hotel Terminal 21
- Green Rich Hotel Osaka Airport
- Century Park Hotel
- Hotel Eldia Yamanashi - Adult only
- Hotels in Marina District
- Melia Kuala Lumpur
- Hotel Plumm
- Seawood Hotel
- Hotels in Kozushima-mura
Flights
Packages