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Check prices for these dates

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Jun 12 - Jun 14
Next weekend
Jun 19 - Jun 21

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Our top choices for Santa Ana hotels

Beach shuttle

Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (195 reviews)
"Very good ."
United States
Denice
The price is ￥4,216
￥14,294 total
includes taxes & fees
Jun 26 - Jun 27
Hotel República
Bar (on property)

Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is ￥3,936
￥4,368 total
includes taxes & fees
Jun 30 - Jul 1
Hotel Riazor
Bar (on property)

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (71 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is ￥4,028
￥4,471 total
includes taxes & fees
Jul 10 - Jul 11
Hostal La Cigarra
Apartment (20) | Iron/ironing board, free WiFi, bed sheets

La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.4 out of 10, Good, (17 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is ￥9,738
￥15,116 total
includes taxes & fees
Jun 15 - Jun 16
La Manzana Barrio Vivo by Wynwood
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (97 reviews)
"Always an amazing stay"
United States
chris
The price is ￥14,140
￥20,359 total
includes taxes & fees
Jun 29 - Jun 30
Casco View Apartments
Front of property

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is ￥5,366
￥5,956 total
includes taxes & fees
Jul 7 - Jul 8
ART CASCO The Hotel
Front of property

Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
Bella Vista, 4.6 km from Santa Ana
9.0 out of 10, Wonderful, (210 reviews)
"This was just an overnight stay, however, staff was super friendly and helpful! Would stay here again!"
United States
Liliana
The price is ￥3,385
￥3,723 total
includes taxes & fees
Jun 17 - Jun 18
Panama House Bed & Breakfast
Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very Good, (1,831 reviews)
"This hotel is very clean and the Staff are very friendly."
United States
Doreen
The price is ￥18,915
￥20,806 total
includes taxes & fees
Jun 12 - Jun 13
Riande Aeropuerto Hotel & Casino
Reception

Hotel Lisboa

Hotel Lisboa
3.0 star property
Calidonia, 1.5 km from Santa Ana
7.6 out of 10, Good, (58 reviews)
"Needs to be updated but the stay was ok. "
United States
Faith
The price is ￥4,217
￥4,649 total
includes taxes & fees
Jul 10 - Jul 11
Hotel Lisboa
Outdoor pool, pool umbrellas, sun loungers

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,587 reviews)
"Great place to stay, restaurant is great also"
United States
Janet
The price is ￥21,782
￥25,017 total
includes taxes & fees
Jun 30 - Jul 1
Crowne Plaza Panama Airport by IHG
Superior Double Room, Garden View | Free WiFi

ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (136 reviews)
"Lovely property, staff was always smiling and it's close to restaurants."
United States
Luis
The price is ￥16,381
￥21,262 total
includes taxes & fees
Jun 12 - Jun 13
ORHO Hotel Boutique 15 Minutes from PTY Airport
View from property

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 12.7 km from Santa Ana
9.6 out of 10, Exceptional, (701 reviews)
"Stunning ! Beautiful Hotel ! Excelent Service Delicious Food Luxury modern room Can’t wait to go back ! Love it so much !"
United States
Marina
The price is ￥38,318
￥42,151 total
includes taxes & fees
Jun 12 - Jun 13
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Exterior

Hotel Milan

Hotel Milan
3.0 star property
El Cangrejo, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (533 reviews)
"Great place to stay"
United States
Kelly
The price is ￥6,406
￥7,047 total
includes taxes & fees
Jun 17 - Jun 18
Hotel Milan
Restaurant

Hotel Costa Inn

Hotel Costa Inn
3.0 star property
Calidonia, 2.1 km from Santa Ana
7.0 out of 10, Good, (599 reviews)
"Rooms are outdated but kept clean. If you are just a one to two day stay, this is worth it. Friendly staff, clean place, restaurant and bar also."
United States
John
The price is ￥4,980
￥5,478 total
includes taxes & fees
Jun 15 - Jun 16
Hotel Costa Inn
Front of property

Hotel California Panama

Hotel California Panama
3.0 star property
Bella Vista, 2.3 km from Santa Ana
8.0 out of 10, Very Good, (100 reviews)
"Clean room, shops and restaurants close by more important the friendly and helpful staff"
United States
Sandra L
The price is ￥5,535
￥6,089 total
includes taxes & fees
Jun 18 - Jun 19
Hotel California Panama
Outdoor pool

Euro Hotel

Euro Hotel
3.0 star property
Calidonia, 2.1 km from Santa Ana
7.8 out of 10, Good, (663 reviews)
"Very convenient for an over night airport stay.. was please with hotel."
United States
Shellyann
The price is ￥5,606
￥6,167 total
includes taxes & fees
Jun 12 - Jun 13
Euro Hotel
Reception

Residencial & Hotel Palazzo

Residencial & Hotel Palazzo
3.0 star property
Calidonia, 1.4 km from Santa Ana
7.4 out of 10, Good, (137 reviews)
"Friendliest guard and night shift workers ive ever met anyplace I’ve traveled"
United States
Cristhian
The price is ￥4,837
￥5,387 total
includes taxes & fees
Jul 10 - Jul 11
Residencial & Hotel Palazzo
Exterior

Hotel Marparaiso

Hotel Marparaiso
3.0 star property
Calidonia, 1.7 km from Santa Ana
7.8 out of 10, Good, (179 reviews)
"Would stay at this hotel all the time. Nice staff"
United States
john
The price is ￥5,823
￥6,406 total
includes taxes & fees
Jun 10 - Jun 11
Hotel Marparaiso
50-inch LED TV with satellite channels

Arcadia Condo Suites

Arcadia Condo Suites
4.0 star property
Costa del Este, 10.2 km from Santa Ana
9.2 out of 10, Wonderful, (302 reviews)
"Everything was amazing"
United States
James
The price is ￥15,055
￥25,017 total
includes taxes & fees
Jun 17 - Jun 18
Arcadia Condo Suites
Reception

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador, 4.8 km from Santa Ana
8.0 out of 10, Very Good, (256 reviews)
"The breakfast was good and lots of parking in a safe place "
United States
Tessa
The price is ￥14,233
￥15,657 total
includes taxes & fees
Jun 22 - Jun 23
MARINN Tropical Vibes Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Ana

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
97 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
71 reviews
View
Beach shuttle
Hotel República
2.0 star property
6.8
195 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View
Bar (on property)
Hotel Riazor
3.0 star property
3.8
11 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
Panama City view old casco viejo antiguo

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Photo by My World
Open Photo by My World

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

Panama City Old Town streets and buildings

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

The Bridge of the Americas in summer, Panama City

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Panoramic view of Panama City Skyline - Panama City, Panama

Calidonia

You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Top Santa Ana Hotel Reviews

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

6/10 Okay
"Terrible guest service. No one answers phone at front desk, housekeeping is very difficult to get through. Bathroom supplies are very limited, towels rarely enough. Rooms and bathrooms broom clean. Every day about the same food in restaurants, no branded alcohol, everything is generic hotel brand. Quiet resort but not very classy. 3 stars the most."
Jerry 5-night trip
Posted less than an hour ago
Dreams Playa Bonita Panama - All Inclusive

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Avenida Balboa and El Machetazo Santa Ana while you're in the neighborhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveler data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 117 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.
What is there to do in this Panama City neighborhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.

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