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Check prices for these dates

Next weekend
Jun 12 - Jun 14
In two weeks
Jun 19 - Jun 21

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Our top choices for Santa Ana hotels

Bar (on property)

Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is ￥4,112
￥4,545 total
includes taxes & fees
Jul 7 - Jul 8
Hotel Riazor
Beach shuttle

Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (195 reviews)
"Very good ."
United States
Denice
The price is ￥4,219
￥14,305 total
includes taxes & fees
Jun 7 - Jun 8
Hotel República
Bar (on property)

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (71 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is ￥4,031
￥4,474 total
includes taxes & fees
Jun 17 - Jun 18
Hostal La Cigarra
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (97 reviews)
"Always an amazing stay"
United States
chris
The price is ￥14,152
￥20,376 total
includes taxes & fees
Jun 29 - Jun 30
Casco View Apartments
Apartment (20) | Iron/ironing board, free WiFi, bed sheets

La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.4 out of 10, Good, (17 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is ￥8,591
￥13,858 total
includes taxes & fees
Jun 7 - Jun 8
La Manzana Barrio Vivo by Wynwood
Front of property

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is ￥5,370
￥5,960 total
includes taxes & fees
Jun 7 - Jun 8
ART CASCO The Hotel
Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very Good, (1,829 reviews)
"This hotel is very clean and the Staff are very friendly."
United States
Doreen
The price is ￥18,930
￥20,823 total
includes taxes & fees
Jun 7 - Jun 8
Riande Aeropuerto Hotel & Casino
Outdoor pool, sun loungers

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (5,563 reviews)
"Excellent breakfast and very nice staff"
United States
Sandra
The price is ￥22,281
￥24,509 total
includes taxes & fees
Jun 29 - Jun 30
Hotel Riu Plaza Panama
Outdoor pool, pool umbrellas, sun loungers

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,580 reviews)
"Great place to stay, restaurant is great also"
United States
Janet
The price is ￥21,799
￥25,037 total
includes taxes & fees
Jul 4 - Jul 5
Crowne Plaza Panama Airport by IHG
Superior Double Room, Garden View | Free WiFi

ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (134 reviews)
"Lovely property, staff was always smiling and it's close to restaurants."
United States
Luis
The price is ￥16,393
￥21,278 total
includes taxes & fees
Jun 7 - Jun 8
ORHO Hotel Boutique 15 Minutes from PTY Airport
Lobby

The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 3.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,139 reviews)
"The Hotel was in a good spot...walking distance to Casinos, Clubs and Restaurants.Staff were helpful and the atmosphere was great"
United States
Samantha Samara
The price is ￥13,304
￥14,634 total
includes taxes & fees
Jun 25 - Jun 26
The Executive Hotel
Free daily buffet breakfast

Best Western El Dorado Panama Hotel

Best Western El Dorado Panama Hotel
3.0 star property
Bethania, 5.5 km from Santa Ana
9.0 out of 10, Wonderful, (722 reviews)
"Great hotel for family visit"
United States
ZULEMA MARTA PHUN
The price is ￥14,490
￥15,939 total
includes taxes & fees
Jun 27 - Jun 28
Best Western El Dorado Panama Hotel
Terrace/patio

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,171 reviews)
"One of my favorite hotels in Panama City, always a great experience and lots of things to do close by, the best breakfast buffet in the area."
United States
Danny
The price is ￥16,552
￥18,207 total
includes taxes & fees
Jun 21 - Jun 22
Plaza Paitilla Inn Hotel
Front of property - evening/night

Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 3.9 km from Santa Ana
9.0 out of 10, Wonderful, (1,883 reviews)
"Great place to stay, wish they had more amenities, but otherwise I will be staying again on my next trip"
United States
Kevin
The price is ￥9,088
￥9,997 total
includes taxes & fees
Jun 8 - Jun 9
Principe Hotel and Suites
Food and drink

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
14.7 km from Santa Ana
9.0 out of 10, Wonderful, (1,009 reviews)
"The staff was phenomenal, the room was clean, and the location was excellent."
United States
Laura
The price is ￥17,492
￥19,241 total
includes taxes & fees
Jun 28 - Jun 29
Courtyard by Marriott Panama Metromall
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
Punta Paitilla, 4 km from Santa Ana
9.2 out of 10, Wonderful, (626 reviews)
"Had a wonderful stay."
Canada
Shawn
The price is ￥25,751
￥28,326 total
includes taxes & fees
Jun 27 - Jun 28
Residence Inn by Marriott Panama City
Front of property

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
Punta Paitilla, 3.6 km from Santa Ana
8.6 out of 10, Excellent, (1,676 reviews)
"Great place to stay in Panama"
United States
EMELY GABRIELA
The price is ￥16,106
￥17,717 total
includes taxes & fees
Jul 5 - Jul 6
Decapolis Hotel Panama City
Breakfast, lunch and dinner served

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 5.1 km from Santa Ana
9.6 out of 10, Exceptional, (1,231 reviews)
"Beautiful and conveniently located.So clean enjoyed the complimentary breakfast close to shopping food .Would stay again."
United States
Alethia
The price is ￥20,197
￥22,217 total
includes taxes & fees
Jun 19 - Jun 20
Ramada Plaza by Wyndham Panama Punta Pacifica
Outdoor pool

Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG
4.0 star property
Campo Alegre, 3.7 km from Santa Ana
8.8 out of 10, Excellent, (1,006 reviews)
"Was a ok stay nothing to complain about Love the breakfast options."
United States
ALDURINE
The price is ￥12,983
￥15,163 total
includes taxes & fees
Jul 3 - Jul 4
Holiday Inn Panama Distrito Financiero by IHG
Reception

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
El Cangrejo, 3.4 km from Santa Ana
8.8 out of 10, Excellent, (553 reviews)
"Nice clean room..and good breakfast"
United States
GEORGE
The price is ￥14,801
￥16,281 total
includes taxes & fees
Jun 8 - Jun 9
Torres de Alba Hotel & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Ana

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
97 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
71 reviews
View
Beach shuttle
Hotel República
2.0 star property
6.8
195 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View
Bar (on property)
Hotel Riazor
3.0 star property
3.8
11 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
Panama City view old casco viejo antiguo

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Photo by My World
Open Photo by My World

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

Panama City Old Town streets and buildings

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

The Bridge of the Americas in summer, Panama City

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Panoramic view of Panama City Skyline - Panama City, Panama

Calidonia

You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Top Santa Ana Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Beautiful lobby. Clean room. Fabulous experience."
Malisa 2-night trip
Posted less than an hour ago
Hotel Riu Plaza Panama

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Avenida Balboa and El Machetazo Santa Ana while you're in the neighborhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveler data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 117 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.
What is there to do in this Panama City neighborhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.

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