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Our top choices for Santa Ana hotels

Hotel Riazor
Hotel Riazor
Hotel República
Hotel República
Hostal La Cigarra
Hostal La Cigarra
Casco View Apartments
Casco View Apartments
La Manzana Barrio Vivo by Wynwood
La Manzana Barrio Vivo by Wynwood
ART CASCO The Hotel
ART CASCO The Hotel
Riande Aeropuerto Hotel & Casino
Riande Aeropuerto Hotel & Casino
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
ORHO Hotel Boutique 15 Minutes from PTY Airport
ORHO Hotel Boutique 15 Minutes from PTY Airport
The Executive Hotel
The Executive Hotel
Best Western El Dorado Panama Hotel
Best Western El Dorado Panama Hotel
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
Principe Hotel and Suites
Principe Hotel and Suites
Courtyard by Marriott Panama Metromall
Courtyard by Marriott Panama Metromall
Residence Inn by Marriott Panama City
Residence Inn by Marriott Panama City
Decapolis Hotel Panama City
Decapolis Hotel Panama City
Ramada Plaza by Wyndham Panama Punta Pacifica
Ramada Plaza by Wyndham Panama Punta Pacifica
Holiday Inn Panama Distrito Financiero by IHG
Holiday Inn Panama Distrito Financiero by IHG
Torres de Alba Hotel & Suites
Torres de Alba Hotel & SuitesCompare popular hotels in Santa Ana
Where to stay in Santa Ana

Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista
Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo
The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Calidonia
You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.
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