Find hotels in Midtown, Key West

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Midtown hotels

The Laureate Key West

The Laureate Key West
3.5 star property
New Town, 3 km from Midtown
9.0 out of 10, Wonderful, (1,014 reviews)
"Great hotel "
United States
David Zion
The price is ¥58,203
¥69,799 total
includes taxes & fees
Mar 1 - Mar 2
The Laureate Key West

Sugar Loaf Lodge

Sugar Loaf Lodge
2.5 star property
24.2 km from Midtown
8.2 out of 10, Very Good, (1,006 reviews)
"Clean, convenient location. "
United States
Michael
The price is ¥45,657
¥51,365 total
includes taxes & fees
Feb 22 - Feb 23
Sugar Loaf Lodge

Two Bedroom Residence With Balcony

Two Bedroom Residence With Balcony
2.0 star property
3.6 km from Midtown
10.0 out of 10, Exceptional, (1 review)
"The roosters crowing early morning was irritating "
United States
Catherine
The price is ¥107,710
¥154,363 total
includes taxes & fees
Mar 2 - Mar 3
Two Bedroom Residence With Balcony

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
3.5 star property
Old Town Key West, 1.4 km from Midtown
9.8 out of 10, Exceptional, (142 reviews)
"We absolutely loved finding this gem to stay on our first visit to Key West. Great location, wonderful staff, and excellent room. "
United States
Sammy
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Coconut Beach Resort

Coconut Beach Resort
2.5 star property
Casa Marina, 1.2 km from Midtown
9.0 out of 10, Wonderful, (153 reviews)
"Room was clean, staff was very helpful, beach was small, close to southernmost point"
United States
Paul
The price is ¥70,247
¥79,027 total
includes taxes & fees
Mar 4 - Mar 5
Coconut Beach Resort

The Saint Hotel Key West, Autograph Collection, Adult Only

The Saint Hotel Key West, Autograph Collection, Adult Only
3.5 star property
Historic Seaport, 2.1 km from Midtown
9.0 out of 10, Wonderful, (350 reviews)
"Fantastic spot, close to everything, but just far enough away. "
United States
Ruth
The price is ¥69,937
¥78,679 total
includes taxes & fees
Mar 4 - Mar 5
The Saint Hotel Key West, Autograph Collection, Adult Only

Fairfield Inn and Suites by Marriott Key West

Fairfield Inn and Suites by Marriott Key West
3.0 star property
New Town, 1.1 km from Midtown
7.8 out of 10, Good, (1,169 reviews)
"Friendly Staff, clean hotel, great breakfast"
United States
Akiem
The price is ¥64,807
¥77,227 total
includes taxes & fees
Mar 15 - Mar 16
Fairfield Inn and Suites by Marriott Key West

The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
4.0 star property
Uptown - Upper Duval, 1.4 km from Midtown
8.6 out of 10, Excellent, (1,006 reviews)
"Hotel was very nice in all respects, but its location on the beach was the best."
United States
Stephen
The price is ¥87,960
¥109,261 total
includes taxes & fees
Mar 8 - Mar 9
The Reach Key West, Curio Collection by Hilton

Seascape Tropical Inn - Adult Exclusive

Seascape Tropical Inn - Adult Exclusive
3.0 star property
Downtown Key West, 1.8 km from Midtown
9.0 out of 10, Wonderful, (419 reviews)
"GOOD PLACE"
United States
Sharad Anilkumar
The price is ¥70,184
¥86,687 total
includes taxes & fees
Mar 15 - Mar 16
Seascape Tropical Inn - Adult Exclusive

The Key West Hotel

The Key West Hotel
2.5 star property
Historic Seaport, 2.1 km from Midtown
9.2 out of 10, Wonderful, (528 reviews)
"Great location, very clean, and great staff"
United States
William
The price is ¥77,267
¥95,324 total
includes taxes & fees
Feb 22 - Feb 23
The Key West Hotel

Weatherstation Inn

Weatherstation Inn
2.5 star property
Truman Annex, 2.4 km from Midtown
9.4 out of 10, Exceptional, (1,001 reviews)
"Awesome location, comfortable, clean room. Very helpful and nice staff"
United States
Kyle
The price is ¥63,081
¥70,966 total
includes taxes & fees
Feb 24 - Feb 25
Weatherstation Inn

Duval Inn

Duval Inn
3.0 star property
Downtown Key West, 1.8 km from Midtown
8.6 out of 10, Excellent, (741 reviews)
"Great little place, just off of Duval St. This was a perfect place as all of old town was walkable. Staff was nice and accomidating, breakfast was ok."
United States
Robert
Duval Inn

Grand Marina Suite by Brightwild Waterfront

Grand Marina Suite by Brightwild Waterfront
2.0 star property
Stock Island, 6 km from Midtown
10.0 out of 10, Exceptional, (3 reviews)
"Nice place "
United States
Pawel
The price is ¥92,018
¥142,345 total
includes taxes & fees
Feb 23 - Feb 24
Grand Marina Suite by Brightwild Waterfront

Aqua Lodges at Hurricane Hole Marina

Aqua Lodges at Hurricane Hole Marina
2.0 star property
Stock Island, 4.1 km from Midtown
8.8 out of 10, Excellent, (178 reviews)
"Unique place to stay! We loved the nature and the location! "
United States
Sara
The price is ¥33,038
¥62,909 total
includes taxes & fees
Mar 1 - Mar 2
Aqua Lodges at Hurricane Hole Marina

Key West Villas

Key West Villas
3.5 star property
Downtown Key West, 1.8 km from Midtown
9.8 out of 10, Exceptional, (252 reviews)
"Awsome staff great location "
United States
Jeffrey
Key West Villas

Colors on White

Colors on White
3.0 star property
Old Town Key West, 1 km from Midtown
8.0 out of 10, Very Good, (407 reviews)
"Beautiful pool with a waterfall. Rooms had everything we needed. "
United States
Chadwick
Colors on White

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West, 0.9 km from Midtown
9.6 out of 10, Exceptional, (1,004 reviews)
"Great location and really nice room. Def stay here again. "
United States
Daniel
The Grand Guesthouse

The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West, 1.4 km from Midtown
9.8 out of 10, Exceptional, (153 reviews)
"Large clean room and excellent staff! Made for a great stay. "
United States
Daniel
The price is ¥74,762
¥84,107 total
includes taxes & fees
Feb 25 - Feb 26
The Conch House Heritage Inn

The Mermaid & Alligator

The Mermaid & Alligator
3.5 star property
Old Town Key West, 1.3 km from Midtown
9.8 out of 10, Exceptional, (285 reviews)
"Clean great staff wonderful breakfast"
United States
Kat
The Mermaid & Alligator

Courtyard by Marriott Key West Waterfront

Courtyard by Marriott Key West Waterfront
3.0 star property
Northside Resort, 2 km from Midtown
8.8 out of 10, Excellent, (1,005 reviews)
"Nice location."
United States
Yongxian
The price is ¥73,099
¥82,236 total
includes taxes & fees
Mar 2 - Mar 3
Courtyard by Marriott Key West Waterfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most. Learn more about Midtown
Learn more about Midtown

Old Town Key West

Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.

Key West Historic District

Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.

Downtown Key West

If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

New Town

Though New Town might not have many top sights, you can venture to the surrounding area to see attractions like Smathers Beach and Fort East Martello Museum and Gallery.

Uptown - Upper Duval

If you're spending some time in Uptown - Upper Duval, Duval Street and Key West Butterfly and Nature Conservatory are top sights worth seeing.

Top Midtown Hotel Reviews

Frequently asked questions

What is Midtown like?
Travelers to the Midtown neighborhood in Key West will be sure to enjoy their stay. Consider a visit to Florida Keys Beaches as part of your Midtown travel plans.
How many hotels will I find in Midtown?
If you're searching for places to stay in Key West, Expedia has something to meet your needs with 54 Midtown hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view top deals in Midtown.
Where can I learn more about changing or cancelling my trip to Midtown?
To access more information about rescheduling or cancelling your trip to Midtown, head over to our customer service page.
What is there to do in this Key West neighborhood?
Florida Keys Beaches is an attraction you might want to check out while you're in Midtown. When you're sightseeing in Key West, Duval Street and Bayview Park are also worth a stop.

Explore a world of travel with Expedia